The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Midbrain circuits for defensive behaviour
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Citations
Cites
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Neuronal circuits for fear and anxiety
Tovote, P., Fadok, J. P., & Lüthi, A. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3945 · Cited by 1,786
Self-citationRethinking the Emotional Brain
LeDoux, J. (2012) · Neuron · doi:10.1016/j.neuron.2012.02.004 · Cited by 1,594
Crouching as an index of fear.
Blanchard, R. J., & Blanchard, D. C. (1969) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0026779 · Cited by 1,077
Evoked axonal oxytocin release in the central amygdala attenuates fear response
Knobloch, H. S., Charlet, A., Hoffmann, L. C., Eliava, M., Khrulev, S., Cetin, A. H., Osten, P., Schwarz, M. K., Seeburg, P. H., Stoop, R., et al. (2012) · Neuron · doi:10.1016/j.neuron.2011.11.030 · Cited by 1,049
Switching on and off fear by distinct neuronal circuits
Herry, C., Ciocchi, S., Senn, V., Demmou, L., Müller, C., & Lüthi, A. (2008) · Nature · doi:10.1038/nature07166 · Cited by 950
Self-citationEncoding of conditioned fear in central amygdala inhibitory circuits
Ciocchi, S., Herry, C., Grenier, F., Wolff, S. B. E., Letzkus, J. J., Vlachos, I., Ehrlich, I., Sprengel, R., Deisseroth, K., Stadler, M. B., et al. (2010) · Nature · doi:10.1038/nature09559 · Cited by 924
Self-citationFrom normal fear to pathological anxiety.
Rosen, J. B., & Schulkin, J. (1998) · Psychological Review · doi:10.1037//0033-295x.105.2.325 · Cited by 882
Functional characteristics of the midbrain periaqueductal gray.
Behbehani, M. M. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(95)00009-k · Cited by 879
A disinhibitory microcircuit for associative fear learning in the auditory cortex
Letzkus, J. J., Wolff, S. B. E., Meyer, E. M. M., Tovote, P., Courtin, J., Herry, C., & Lüthi, A. (2011) · Nature · doi:10.1038/nature10674 · Cited by 840
Self-citation
Cited by
Integration of optogenetics with complementary methodologies in systems neuroscience
Kim, C. K., Adhikari, A., & Deisseroth, K. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.15 · Cited by 690
Self-citationA synaptic threshold mechanism for computing escape decisions
Evans, D. A., Stempel, A. V., Vale, R., Ruehle, S., Lefler, Y., & Branco, T. (2018) · Nature · doi:10.1038/s41586-018-0244-6 · Cited by 449
Synapse-specific astrocyte gating of amygdala-related behavior
Martin-Fernandez, M., Jamison, S., Robin, L. M., Zhao, Z., Martin, E. D., Aguilar, J., Benneyworth, M. A., Marsicano, G., & Araque, A. (2017) · Nature Neuroscience · doi:10.1038/nn.4649 · Cited by 345
A Visual Circuit Related to Habenula Underlies the Antidepressive Effects of Light Therapy
Huang, L., Xi, Y., Peng, Y., Yang, Y., Huang, X., Fu, Y., Tao, Q., Xiao, J., Yuan, T., An, K., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.01.037 · Cited by 300
Dopamine enhances signal-to-noise ratio in cortical-brainstem encoding of aversive stimuli
Vander Weele, C. M., Siciliano, C. A., Matthews, G. A., Namburi, P., Izadmehr, E. M., Espinel, I. C., Nieh, E. H., Schut, E. H. S., Padilla-Coreano, N., Burgos-Robles, A., et al. (2018) · Nature · doi:10.1038/s41586-018-0682-1 · Cited by 298
Metadata
- Authors
- Tovote, P., Esposito, M. S., Botta, P., Chaudun, F., Fadok, J. P., Markovic, M., Wolff, S. B. E., Ramakrishnan, C., Fenno, L., Deisseroth, K., Herry, C., Arber, S., & Lüthi, A.
- Venue
- Nature
- Published
- 2016-06-01
- Volume
- 534
- Issue
- 7606
- Pages
- 206-212
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2415217866
- Cited by
- 732
- References
- 49
- FWCI
- 40.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Midbrain circuits for defensive behaviour. https://app.cochat.ai/papers/10.1038/nature17996
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- Tovote, P., Esposito, M. S., Botta, P., Chaudun, F., Fadok, J. P., Markovic, M., Wolff, S. B. E., Ramakrishnan, C., Fenno, L., Deisseroth, K., Herry, C., Arber, S., & Lüthi, A. (2016). Midbrain circuits for defensive behaviour. Nature. https://doi.org/10.1038/nature17996
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
