Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

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   Anand V. R. Kornepati, Ratna K. Vadlamudi, Tyler Jay Curiel · 2022 · Nature reviews. Cancer
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4. Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment
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   Karl L. Banta, Xiaozheng Xu, Avantika S. Chitre, Amelia Au‐Yeung, Chikara Takahashi, William E. O’Gorman, Thomas D. Wu, Stephanie Mittman, Rafael A. Cubas, Laëtitia Comps‐Agrar et al. · 2022 · Immunity
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   Weiting Qin, Li-Peng Hu, Xueli Zhang, Shuheng Jiang, Jun Li, Zhigang Zhang, Xu Wang · 2019 · Frontiers in Immunology
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    Lanitis, E., Dangaj, D., Irving, M., Coukos, G. · 2017 · Annals of Oncology
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    Xiao Qian Wang, Esther Danenberg, Chiun‐Sheng Huang, Daniel Egle, Maurizio Callari, Begoña Bermejo, Matteo Dugo, Claudio Zamagni, Marc Thill, Anton Anton et al. · 2023 · Nature
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    Ilaria Elia, Jared H. Rowe, Sheila E. Johnson, Shakchhi Joshi, Giulia Notarangelo, Kiran Kurmi, Sarah A. Weiss, Gordon James Freeman, Arlene H. Sharpe, Marcia C. Haigis · 2022 · Cell Metabolism
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    Kelly Kersten, Kenneth H. Hu, Alexis J. Combes, Bushra Samad, Tory Harwin, Arja Ray, Arjun Arkal Rao, En Cai, Kyle Marchuk, Jordan Artichoker et al. · 2021 · Cancer Cell
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    Englinger, Bernhard, Pirker, Christine, Heffeter, Petra, Terenzi, Alessio, Kowol, Christian R., Keppler, Bernhard K., Berger, Walter · 2019 · Chemical Reviews
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    Alireza Saeidi, Keivan Zandi, Yi Ying Cheok, Hamidreza Saeidi, Won Fen Wong, Chalystha Yie Qin Lee, Heng Choon Cheong, Yean Kong Yong, Marie Larsson, Esaki Muthu Shankar · 2018 · Frontiers in Immunology
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    Hyungseok Seo, Edahí González‐Avalos, Wade Zhang, Payal Ramchandani, Chao Yang, Chan‐Wang Jerry Lio, Anjana Rao, Patrick G. Hogan · 2021 · Nature Immunology
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    Chao Liu, Xue Liu, Xinchu Xiang, Xin Pang, Siyuan Chen, Yunming Zhang, En Ren, Lili Zhang, Xuan Liu, Peng Lv et al. · 2022 · Nature Nanotechnology
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    Vidhya Madapusi Ravi, Nicolas Noel Neidert, Paulina Will, Kevin Joseph, Julian P. Maier, Jan Kückelhaus, Lea Vollmer, Jonathan M. Goeldner, Simon P. Behringer, Florian Scherer et al. · 2022 · Nature Communications
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    Hongbo Chi, Marion Pepper, Paul Glyndwr Thomas · 2024 · Cell
22. Exhausted CD8+T Cells in the Tumor Immune Microenvironment: New Pathways to Therapy
    Weiqin Jiang, Yinjun He, Wenguang He, Guosheng S. Wu, Xile Zhou, Qinsong Sheng, Weixiang Zhong, Yimin Lu, Yongfeng Ding, Lu Qi et al. · 2021 · Frontiers in Immunology
23. Targeting the Latent Reservoir for HIV-1
    Srona Sengupta, Robert F. Siliciano · 2018 · Immunity
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    Anliang Xia, Yan Zhang, Xu Jiang, Tailang Yin, Xiaojie Lu · 2019 · Frontiers in Immunology
25. High-dimensional single cell analysis identifies stem-like cytotoxic CD8+ T cells infiltrating human tumors
    Brummelman, Jolanda, Mazza, Emilia M.C., Alvisi, Giorgia, Colombo, Federico S., Grilli, Andrea, Mikulak, Joanna, Mavilio, Domenico, Alloisio, Marco, Ferrari, Francesco, Lopci, Egesta et al. · 2018 · Journal of Experimental Medicine
26. Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer
    Christiane Sigrid Eberhardt, Haydn Thomas Kissick, Mihir R. Patel, Maria Andrea Cardenas, Nataliya Prokhnevska, Rebecca C. Obeng, Tahseen H. Nasti, Christopher C. Griffith, Se Jin Im, Xu Wang et al. · 2021 · Nature
27. Immune evasion through mitochondrial transfer in the tumour microenvironment
    Ikeda, Hideki, Kawase, Katsushige, Nishi, Tatsuya, Watanabe, Tomofumi, Takenaga, Keizo, Inozume, Takashi, Ishino, Takamasa, Aki, Sho, Lin, Jason, Kawashima, Shusuke et al. · 2025 · Nature
28. Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans
    Galletti, Giovanni, De Simone, Gabriele, Mazza, Emilia M. C., Puccio, Simone, Mezzanotte, Claudia, Bi, Timothy M., Davydov, Alexey N., Metsger, Maria, Scamardella, Eloise, Alvisi, Giorgia et al. · 2020 · Nature Immunology
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    Hao Wu, Xiufeng Zhao, Sophia M. Hochrein, Miriam Eckstein, Gabriela Farias Gubert, Konrad Knöpper, Ana Maria Mansilla, Arman Öner, Rémi Doucet-Ladevèze, Werner Schmitz et al. · 2023 · Nature Communications
30. CD8 T-cell subsets: heterogeneity, functions, and therapeutic potential
    Choong‐Hyun Koh, Suyoung Lee, Minkyeong Kwak, Byung‐Seok Kim, Yeonseok Chung · 2023 · Experimental & Molecular Medicine
31. PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
    Masao Hashimoto, Koichi Araki, Maria Andrea Cardenas, Peng Li, Rohit R. Jadhav, Haydn Thomas Kissick, William H. Hudson, Donald J. McGuire, Rebecca C. Obeng, Andreas Wieland et al. · 2022 · Nature
32. Epigenetic regulation of T cell exhaustion
    Julia A. Belk, Bence Dániel, Ansuman T. Satpathy · 2022 · Nature Immunology
33. Mechanisms of action and rationale for the use of checkpoint inhibitors in cancer
    Clémence Granier, Éléonore De Guillebon, Charlotte Blanc, Helene Roussel, Cécile Badoual, Elia Colin, Antonin Saldmann, Alain Gey, Stéphane Marie. Oudard, Éric Tartour · 2017 · ESMO Open
34. Extended release of perioperative immunotherapy prevents tumor recurrence and eliminates metastases
    Chun Gwon Park, Christina Hartl, Daniela Schmid, Ellese M. Carmona, Hye‐Jung Kim, Michael S. Goldberg · 2018 · Science Translational Medicine
35. Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells
    Bertram Bengsch, Takuya Ohtani, Omar Khan, Manu N. Setty, Sasikanth Manne, Shaun O’Brien, Pier Federico Gherardini, Ramin S. Herati, Alexander Chan Chi Huang, Kyong‐Mi Chang et al. · 2018 · Immunity
36. Early precursor T cells establish and propagate T cell exhaustion in chronic infection
    Daniel T. Utzschneider, Sarah S. Gabriel, David Chisanga, Renee Gloury, Patrick M. Gubser, Ajithkumar Vasanthakumar, Wei Shi, Axel Kallies · 2020 · Nature Immunology
37. CD8+ T cell exhaustion
    Makoto Kurachi · 2019 · Seminars in Immunopathology
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    Chuansheng Guo, Zhiyuan You, Hao Shi, Yu Sun, Xingrong Du, Gustavo F. Palacios, Cliff S. Guy, Sujing Yuan, Nicole M. Chapman, Seon Ah Lim et al. · 2023 · Nature
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    Anna-Maria Globig, Steven Zhao, Jessica Roginsky, Vivien Ileana Maltez, Juan Güiza, Natalia Avina-Ochoa, Maximilian Heeg, Filipe Araujo Hoffmann, Omkar Chaudhary, Jiawei Wang et al. · 2023 · Nature
40. Single-cell meta-analyses reveal responses of tumor-reactive CXCL13+ T cells to immune-checkpoint blockade
    Liu, Baolin, Zhang, Yuanyuan, Wang, Dongfang, Hu, Xueda, Zhang, Zemin · 2022 · Nature Cancer
41. FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells
    Meng, Xiangbo, Liu, Xiwei, Guo, Xingdong, Jiang, Shutan, Chen, Tingting, Hu, Zhiqiang, Liu, Haifeng, Bai, Yibing, Xue, Manman, Hu, Ronggui et al. · 2018 · Nature
42. Mechanisms and dynamics of T cell-mediated cytotoxicity in vivo
    Halle, Stephan, Halle, Olga, Förster, Reinhold · 2017 · Trends in Immunology
43. Reversing T-cell Exhaustion in Cancer: Lessons Learned from PD-1/PD-L1 Immune Checkpoint Blockade
    Natalija Budimir, Graham D. Thomas, Joseph S. Dolina, Shahram Salek‐Ardakani · 2021 · Cancer Immunology Research
44. Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
    Jason M. Schenkel, Rebecca H. Herbst, David A. Canner, Amy Li, Michelle Hillman, Sean-Luc Shanahan, Grace Gibbons, Olivia C. Ghirardelli Smith, Jonathan Y. Kim, Peter M.K. Westcott et al. · 2021 · Immunity
45. PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
    Laura Codarri Deak, Valeria Nicolini, Masao Hashimoto, Maria Karagianni, Petra Catalina Schwalie, Laura Lauener, Eleni Maria Varypataki, Marine Richard, Esther Bommer, Johannes Sam et al. · 2022 · Nature
46. Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity
    Vignali, Paolo D. A., DePeaux, Kristin, Watson, McLane J., Ye, Chenxian, Ford, B. Rhodes, Lontos, Konstantinos, McGaa, Nicole K., Scharping, Nicole E., Menk, Ashley V., Robson, Simon C. et al. · 2023 · Nature Immunology
47. Advances in cancer immunotherapy: historical perspectives, current developments, and future directions
    Mei‐Yin Zhang, Chao-jun Liu, Jing Tu, Min Tang, Milad Ashrafizadeh, Noushin Nabavi, Gautam Sethi, Peiqing Zhao, Shijian Liu · 2025 · Molecular Cancer
48. Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy
    J. Justin Milner, Clara Toma, Zhaoren He, Nadia S. Kurd, Quynh Nguyen, Bryan McDonald, Lauren K. Quezada, Christella E. Widjaja, Deborah A. Witherden, John T. Crowl et al. · 2020 · Immunity
49. Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
    Schnell, Alexandra, Huang, Linglin, Singer, Meromit, Singaraju, Anvita, Barilla, Rocky M., Regan, Brianna M.L., Bollhagen, Alina, Thakore, Pratiksha I., Dionne, Danielle, Delorey, Toni M. et al. · 2021 · Cell
50. Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey
    Mohamed A. ElTanbouly, Randolph J. Noelle · 2020 · Nature reviews. Immunology
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    Jianjun Qin, Liyan Xue, Anlin Hao, Xiaofeng Guo, Tao Jiang, Yunfeng Ni, Shuoyan Liu, Yujie Chen, Hongjing Jiang, Chen Zhang et al. · 2024 · Nature Medicine
52. MYB orchestrates T cell exhaustion and response to checkpoint inhibition
    Carlson Tsui, Lorenz Kretschmer, Svenja Rapelius, Sarah S. Gabriel, David Chisanga, Konrad Knöpper, Daniel T. Utzschneider, Simone Nüssing, Yang Liao, Teisha Mason et al. · 2022 · Nature
53. Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
    Giles, Josephine R., Ngiow, Shin Foong, Manne, Sasikanth, Baxter, Amy E., Khan, Omar, Wang, Ping, Staupe, Ryan, Abdel-Hakeem, Mohamed S., Huang, Hua, Mathew, Divij et al. · 2022 · Nature Immunology
54. A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer
    Ning Cheng, Rebekah Watkins-Schulz, Robert D. Junkins, Clément N. David, Brandon M. Johnson, Stephanie A. Montgomery, Kevin J. Peine, David B. Darr, Hong Yuan, Karen P. McKinnon et al. · 2018 · JCI Insight
55. Cancer therapy with antibodies
    Suman Paul, Maximilian F. Konig, Drew M. Pardoll, Chetan Bettegowda, Nickolas Papadopoulos, Katharine M. Wright, Sandra B. Gabelli, Mitchell Ho, Andrea van Elsas, Shibin Zhou · 2024 · Nature reviews. Cancer
56. Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
    Jeremy Baldwin, Christoph Heuser-Loy, Tanmoy Saha, Roland Christian Schelker, Dragana Slavkovic‐Lukic, Nicholas Strieder, Inmaculada Hernandez-Lopez, Nisha Rana, Markus Barden, Fabio Mastrogiovanni et al. · 2024 · Cell
57. The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells
    Henrique Borges da Silva, Lalit K. Beura, Haiguang Wang, Eric Allan Hanse, Reshma Gore, Milcah C. Scott, Daniel Walsh, Katharine E. Block, Raíssa Fonseca, Yan Yan et al. · 2018 · Nature
58. Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer
    James D. Clarke, Bharat Panwar, Ariel Madrigal, Divya Kumari Singh, Ravindra Gujar, Oliver Wood, Serena Chee, Simon Eschweiler, Emma Victoria King, Amiera S. Awad et al. · 2019 · The Journal of Experimental Medicine
59. Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation
    Mohamed S. Abdel-Hakeem, Sasikanth Manne, Jean‐Christophe Beltra, Erietta Stelekati, Zeyu Chen, Kito Nzingha, Mohammed-Alkhatim Ali, John L. Johnson, Josephine Ruth Giles, Divij Mathew et al. · 2021 · Nature Immunology
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    Aung Naing, Jeffrey R. Infante, Kyriakos P. Papadopoulos, Ivan H. Chan, Cong Shen, Navneet P. Ratti, Bianca Rojo, Karen A. Autio, Deborah J. L. Wong, Manish R. Patel et al. · 2018 · Cancer Cell
61. Multiplexed imaging mass cytometry of the chemokine milieus in melanoma characterizes features of the response to immunotherapy
    Tobias Hoch, Daniel Schulz, Nils Eling, Julia M. Martínez Gómez, Mitchell P. Levesque, Bernd Bodenmiller · 2022 · Science Immunology
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    Martin W. LaFleur, Thao H. Nguyen, Matthew A. Coxe, Brian C. Miller, Kathleen B. Yates, Jacob E. Gillis, Debattama R. Sen, Emily F. Gaudiano, Rose Al Abosy, Gordon James Freeman et al. · 2019 · Nature Immunology
63. TCF1 in T cell immunity: a broadened frontier
    Xudong Zhao, Qiang Shan, Hai‐Hui Xue · 2021 · Nature reviews. Immunology
64. Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity
    Collier, Jenna L., Weiss, Sarah A., Pauken, Kristen E., Sen, Debattama R., Sharpe, Arlene H. · 2021 · Nature Immunology
65. Signaling networks in immunometabolism
    Jordy Saravia, Jana L. Raynor, Nicole M. Chapman, Seon Ah Lim, Hongbo Chi · 2020 · Cell Research
66. Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells
    Masahiro Okada, Shunsuke Chikuma, Taisuke Kondo, Sana Hibino, Hiroaki Machiyama, Tadashi Yokosuka, Miyako Nakano, Akihiko Yoshimura · 2017 · Cell Reports
67. Cellular metabolism regulates the differentiation and function of T-cell subsets
    Sicong Ma, Yanan Ming, Jingxia Wu, Guoliang Cui · 2024 · Cellular and Molecular Immunology
68. Androgen conspires with the CD8 + T cell exhaustion program and contributes to sex bias in cancer
    Hyunwoo Kwon, Johanna M. Schafer, No‐Joon Song, Satoshi Kaneko, Anqi Li, Tong Xiao, Anjun Ma, Carter Allen, Komal Das, Lei Zhou et al. · 2022 · Science Immunology
69. Cellular networks controlling T cell persistence in adoptive cell therapy
    Jack D. Chan, Junyun Lai, Clare Y. Slaney, Axel Kallies, Paul A. Beavis, Phillip Kevin Darcy · 2021 · Nature reviews. Immunology
70. Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment
    Victor Andrés Arrieta, Crismita Dmello, Daniel James McGrail, Daniel Jay Brat, Catalina Lee-Chang, Amy B. Heimberger, Dhan Sidhartha Chand, Roger Stupp, Adam M. Sonabend · 2023 · Journal of Clinical Investigation
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    David Mark Francis, Margaret Patricia Manspeaker, Alex Schudel, Lauren F. Sestito, Meghan J. O’Melia, Haydn Thomas Kissick, Brian P. Pollack, Edmund K. Waller, Susan Napier Thomas · 2020 · Science Translational Medicine
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    Divij Mathew, Melina Elpi Marmarelis, Caitlin Foley, Joshua Michael Bauml, Darwin Ye, Reem Ghinnagow, Shin Foong Ngiow, Max Klapholz, Soyeong Jun, Zhaojun Zhang et al. · 2024 · Science
73. TOX is expressed by exhausted and polyfunctional human effector memory CD8 + T cells
    Takuya Sekine, André Perez‐Potti, Son Nguyen, Jean‐Baptiste Gorin, Vincent H. Wu, Emma Gostick D, Sian Llewellyn‐Lacey, Quirin Hammer, Sara Falck‐Jones, Sindhu Vangeti et al. · 2020 · Science Immunology
74. Hodgkin lymphoma
    Joseph Michael Connors, Wendy Cozen, Christian Steidl, Antonino Carbone, Richard T. Hoppe, Hans‐Henning Flechtner, Nancy L. Bartlett · 2020 · Nature Reviews Disease Primers
75. Rheumatic immune-related adverse events from cancer immunotherapy
    Leonard H. Calabrese, Cassandra M. Calabrese, Laura C. Cappelli · 2018 · Nature Reviews Rheumatology
76. Impact of PD-1 Blockade on Severity of COVID-19 in Patients with Lung Cancers
    Jia Luo, Hira A. Rizvi, Jacklynn V. Egger, Isabel Ruth Preeshagul, Jedd D. Wolchok, Matthew David Hellmann · 2020 · Cancer Discovery
77. Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8 + T cells
    Anthony Kusnadi, Ciro Ramírez-Suástegui, Vicente Fajardo, Serena Chee, Benjamin J. Meckiff, Hayley A. Simon, Emanuela Pelosi, Grégory Seumois, Ferhat Ay, Pandurangan Vijayanand et al. · 2021 · Science Immunology
78. Memory T cell, exhaustion, and tumor immunity
    Makoto Ando, Minako Ito, Tanakorn Srirat, Taisuke Kondo, Akihiko Yoshimura · 2019 · Immunological Medicine
79. CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
    Moran Yang, Jiaqi Lu, Guodong Zhang, Yiying Wang, Mengdi He, Qing Xu, Congjian Xu, Haiou Liu · 2021 · Journal for ImmunoTherapy of Cancer
80. TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy
    Eugene Y. Chiang, Ira Mellman · 2022 · Journal for ImmunoTherapy of Cancer
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    Dietmar Zehn, Robert Thimme, Enrico Lugli, Gustavo Pereira de Almeida, Annette Oxenius · 2022 · Nature Immunology
82. FOXO1 is a master regulator of memory programming in CAR T cells
    Alexander E. Doan, Katherine P. Mueller, Andy Y. Chen, Geoffrey T. Rouin, Yingshi Chen, Bence Dániel, John Lattin, Martina Markovska, Brett Mozarsky, Jose Arias-Umana et al. · 2024 · Nature
83. Divergent clonal differentiation trajectories of T cell exhaustion
    Bence Dániel, Kathryn E. Yost, Sunnie Hsiung, Katalin Sándor, Yu Xia, Yanyan Qi, Kamir J. Hiam-Galvez, Mollie Black, Colin J. Raposo, Quanming Shi et al. · 2022 · Nature Immunology
84. Rational design of anti-GITR-based combination immunotherapy
    Roberta Zappasodi, Cynthia A. Sirard, Yanyun Li, Sadna Budhu, Mohsen Abu-Akeel, Cailian Liu, Xia Yang, Hong Zhong, Walter Newman, Jingjing Qi et al. · 2019 · Nature Medicine
85. Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells
    Johnson, John L., Georgakilas, Georgios, Petrovic, Jelena, Kurachi, Makoto, Cai, Stanley, Harly, Christelle, Pear, Warren S., Bhandoola, Avinash, Wherry, E. John, Vahedi, Golnaz · 2018 · Immunity
86. The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
    Alexandra Schnell, Lloyd Bod, Asaf Madi, Vijay Kumar Kuchroo · 2020 · Cell Research
87. Effect of immunotherapy time-of-day infusion on overall survival among patients with advanced melanoma in the USA (MEMOIR): a propensity score-matched analysis of a single-centre, longitudinal study
    David C Qian, Troy Kleber, Brianna Brammer, Karen M Xu, Jeffrey M Switchenko, James R Janopaul-Naylor, Jim Zhong, Melinda L Yushak, R Donald Harvey, Chrystal Mary Paulos et al. · 2021 · The Lancet Oncology
88. Autoimmune diseases and immune-checkpoint inhibitors for cancer therapy: Review of the literature and personalized risk-based prevention strategy
    Haanen, J., Ernstoff, M.S., Wang, Y., Menzies, A.M., Puzanov, I., Grivas, P., Larkin, J., Peters, S., Thompson, J.A., Obeid, M. · 2020 · Annals of Oncology
89. Canonical and Non-Canonical Wnt Signaling in Immune Cells
    Chae, Wook-Jin, Bothwell, Alfred L.M. · 2018 · Trends in Immunology
90. Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade
    Rohit R. Jadhav, Se Jin Im, Bin Hu, Masao Hashimoto, Peng Li, Jian‐Xin Lin, Warren J. Leonard, William James Greenleaf, Rafi Ahmed, Jörg J. Goronzy · 2019 · Proceedings of the National Academy of Sciences
91. Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment
    Faezzah Baharom, Ramiro A. Ramirez-Valdez, Ahad Khalilnezhad, Shabnam Khalilnezhad, Marlon Dillon, Dalton Hermans, Sloane Christian Fussell, Kennedy K.S. Tobin, Charles‐Antoine Dutertre, Geoffrey M. Lynn et al. · 2022 · Cell
92. Stem-like exhausted and memory CD8+ T cells in cancer
    Thomas Gebhardt, Simone L. Park, Ian A. Parish · 2023 · Nature reviews. Cancer
93. TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation
    Dominik Wieland, Janine Sophie Kemming, Anita Schuch, Florian Emmerich, Percy Alexander Knolle, Christoph Neumann‐Haefelin, Werner Held, Dietmar Zehn, Maike Hofmann, Robert Thimme · 2017 · Nature Communications
94. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
    Karmaus, Peer W. F., Chen, Xiang, Lim, Seon Ah, Herrada, Andrés A., Nguyen, Thanh-Long M., Xu, Beisi, Dhungana, Yogesh, Rankin, Sherri, Chen, Wenan, Rosencrance, Celeste et al. · 2019 · Nature
95. Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors
    Liangliang Xu, Chang Zou, Shanshan Zhang, Timothy Shun Man Chu, Yan Zhang, Weiwei Chen, Cai‐Ning Zhao, Yang Li, Zhiyuan Xu, Shaowei Dong et al. · 2022 · Journal of Hematology & Oncology
96. T cell factor 1: A master regulator of the T cell response in disease
    Escobar, Giulia, Mangani, Davide, Anderson, Ana C. · 2020 · Science Immunology
97. Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy
    Gregory M. Chen, Changya Chen, Rajat Kumar Das, Peng Gao, Chia‐Hui Chen, Shovik Bandyopadhyay, Yangyang Ding, Yasin Uzun, Wenbao Yu, Qin Zhu et al. · 2021 · Cancer Discovery
98. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
    Zeyu Chen, Eri Arai, Omar Khan, Zhen Zhang, Shin Foong Ngiow, Yuan Ming He, Hua Huang, Sasikanth Manne, Zhendong Cao, Amy E. Baxter et al. · 2021 · Cell
99. Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    Jinjia Zhang, Junhong Li, Yongqiang Hou, Yao Lin, Hao Zhao, Yiran Shi, Kaiyun Chen, Cheng Nian, Jiayu Tang, Lei Pan et al. · 2024 · Cell
100. Chimeric antigen receptor T cell persistence and memory cell formation
     Alexander Donald McLellan, Seyed Mohammad Ali Hosseini Rad · 2019 · Immunology and Cell Biology