Ahmed, Rafi

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Day, C. L., Kaufmann, D. E., Kiepiela, P., Brown, J. A., Moodley, E. S., Reddy, S., Mackey, E. W., Miller, J. D., Leslie, A. J., DePierres, C., et al. (2006) · Nature

HIV Research and TreatmentT-cell and B-cell Immunology

Cited by 2,680

Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

Wherry, E. J., Ha, S.-J., Kaech, S. M., Haining, W. N., Sarkar, S., Kalia, V., Subramaniam, S., Blattman, J. N., Barber, D. L., & Ahmed, R. (2007) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 2,103

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

Im, S. J., Hashimoto, M., Gerner, M. Y., Lee, J., Kissick, H. T., Burger, M. C., Shan, Q., Hale, J. S., Lee, J., Nasti, T. H., et al. (2016) · Nature

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 2,070

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

Zajac, A. J., Blattman, J. N., Murali-Krishna, K., Sourdive, D. J. D., Suresh, M., Altman, J. D., & Ahmed, R. (1998) · The Journal of Experimental Medicine

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,978

Effector and memory T-cell differentiation: implications for vaccine development

Kaech, S. M., Wherry, E. J., & Ahmed, R. (2002) · Nature Reviews Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,865

Lineage relationship and protective immunity of memory CD8 T cell subsets

Wherry, E. J., Teichgräber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H., & Ahmed, R. (2003) · Nature Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,864

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

Kaech, S. M., Tan, J. T., Wherry, E. J., Konieczny, B. T., Surh, C. D., & Ahmed, R. (2003) · Nature Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,830

Immunological memory and protective immunity: understanding their relation

Ahmed, R., & Gray, D. (1996) · Science

T-cell and B-cell ImmunologyImmune responses and vaccinations

Cited by 1,775

mTOR regulates memory CD8 T-cell differentiation

Araki, K., Turner, A. P., Shaffer, V. O., Gangappa, S., Keller, S. A., Bachmann, M. F., Larsen, C. P., & Ahmed, R. (2009) · Nature

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 1,575

Redefining Chronic Viral Infection

Virgin, H. W., Wherry, E. J., & Ahmed, R. (2009) · Cell

Bacteriophages and microbial interactionsHepatitis B Virus Studies

Cited by 1,031

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

Kamphorst, A. O., Wieland, A., Nasti, T., Yang, S., Zhang, R., Barber, D. L., Konieczny, B. T., Daugherty, C. Z., Koenig, L., Yu, K., et al. (2017) · Science

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 1,015

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

Jin, H.-T., Anderson, A. C., Tan, W. G., West, E. E., Ha, S.-J., Araki, K., Freeman, G. J., Kuchroo, V. K., & Ahmed, R. (2010) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 858

Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1–targeted therapy in lung cancer patients

Kamphorst, A. O., Pillai, R. N., Yang, S., Nasti, T. H., Akondy, R. S., Wieland, A., Sica, G. L., Yu, K., Koenig, L., Patel, N. T., et al. (2017) · Proceedings of the National Academy of Sciences

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 854

Cutting edge: long-term B cell memory in humans after smallpox vaccination

Crotty, S., Felgner, P., Davies, H., Glidewell, J., Villarreal, L., & Ahmed, R. (2003) · The Journal of Immunology

Poxvirus research and outbreaksT-cell and B-cell Immunology

Cited by 695

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

Hudson, W. H., Gensheimer, J., Hashimoto, M., Wieland, A., Valanparambil, R. M., Li, P., Lin, J.-X., Konieczny, B. T., Im, S. J., Freeman, G. J., et al. (2019) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 656

Dynamic T cell migration program provides resident memory within intestinal epithelium

Masopust, D., Choo, D., Vezys, V., Wherry, E. J., Duraiswamy, J., Akondy, R., Wang, J., Casey, K. A., Barber, D. L., Kawamura, K. S., et al. (2010) · Journal of Experimental Medicine

T-cell and B-cell ImmunologyCell Adhesion Molecules Research

Cited by 628

Heterologous immunity provides a potent barrier to transplantation tolerance

Adams, A. B., Williams, M. A., Jones, T. R., Shirasugi, N., Durham, M. M., Kaech, S. M., Wherry, E. J., Onami, T., Lanier, J. G., Kokko, K. E., et al. (2003) · Journal of Clinical Investigation

T-cell and B-cell ImmunologyTransplantation: Methods and Outcomes

Cited by 616

Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines

Miller, J. D., van der Most, R. G., Akondy, R. S., Glidewell, J. T., Albott, S., Masopust, D., Murali-Krishna, K., Mahar, P. L., Edupuganti, S., Lalor, S., et al. (2008) · Immunity

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 601

Origin and differentiation of human memory CD8 T cells after vaccination

Akondy, R. S., Fitch, M., Edupuganti, S., Yang, S., Kissick, H. T., Li, K. W., Youngblood, B. A., Abdelsamed, H. A., McGuire, D. J., Cohen, K. W., et al. (2017) · Nature

T-cell and B-cell ImmunologyImmune responses and vaccinations

Cited by 517

Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients

Suthar, M. S., Zimmerman, M. G., Kauffman, R. C., Mantus, G., Linderman, S. L., Hudson, W. H., Vanderheiden, A., Nyhoff, L., Davis, C. W., Adekunle, O., et al. (2020) · Cell Reports Medicine

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 508

Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells

Cohen, K. W., Linderman, S. L., Moodie, Z., Czartoski, J., Lai, L., Mantus, G., Norwood, C., Nyhoff, L. E., Edara, V. V., Floyd, K., et al. (2021) · Cell Reports Medicine

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 441

NFATc1 Regulates PD-1 Expression upon T Cell Activation

Oestreich, K. J., Yoon, H., Ahmed, R., & Boss, J. M. (2008) · The Journal of Immunology

Signaling Pathways in DiseaseT-cell and B-cell Immunology

Cited by 416

Systems analysis of immunity to influenza vaccination across multiple years and in diverse populations reveals shared molecular signatures

Nakaya, H. I., Hagan, T., Duraisingham, S. S., Lee, E. K., Kwissa, M., Rouphael, N., Frasca, D., Gersten, M., Mehta, A. K., Gaujoux, R., et al. (2015) · Immunity

Influenza Virus Research StudiesImmune responses and vaccinations

Cited by 337

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

Ray, J. P., Staron, M. M., Shyer, J. A., Ho, P.-C., Marshall, H. D., Gray, S. M., Laidlaw, B. J., Araki, K., Ahmed, R., Kaech, S. M., et al. (2015) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 315