Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

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Items 101–200 of 947

1. Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
   Lei, Yong, Zhang, Xiaotian, Su, Jianzhong, Jeong, Mira, Gundry, Michael C., Huang, Yung-Hsin, Zhou, Yubin, Li, Wei, Goodell, Margaret A. · 2017 · Nature Communications
2. Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs
   Peiqing Zhang, Susanto Woen, Tianhua Wang, Brian Liau, Sophie Zhao, Chen Chen, Yuansheng Yang, Zhiwei Song, Mark R. Wormald, Chuanfei Yu et al. · 2016 · Drug Discovery Today
3. Structural basis for Cas9 off-target activity
   Pacesa, Martin, Lin, Chun-Han, Cléry, Antoine, Saha, Aakash, Arantes, Pablo R., Bargsten, Katja, Irby, Matthew J., Allain, Frédéric H.-T., Palermo, Giulia, Cameron, Peter et al. · 2022 · Cell
4. CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems
   Wenyan Jiang, Luciano A. Marraffini · 2015 · Annual Review of Microbiology
5. Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9
   Taeyoung Koo, Jungjoon Lee, Jin‐Soo Kim · 2015 · Molecules and Cells
6. Simple and Rapid In Vivo Generation of Chromosomal Rearrangements using CRISPR/Cas9 Technology
   Rafael B. Blasco, Elif Karaca, Chiara Ambrogio, Taek-Chin Cheong, Emre Karayol, Valerio Giacomo Minero, Claudia Voena, Roberto Chiarle · 2014 · Cell Reports
7. The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit
   Karthik Murugan, Kesavan Babu, Ramya Sundaresan, Rakhi Rajan, Dipali G. Sashital · 2017 · Molecular Cell
8. Discovery of proteins associated with a predefined genomic locus via dCas9–APEX-mediated proximity labeling
   Samuel A. Myers, Jason B. Wright, Ryan Peckner, Brian Thomas Kalish, Feng Zhang, Steven A. Carr · 2018 · Nature Methods
9. High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
   Evan A. Boyle, Johan O. L. Andreasson, Lauren M. Chircus, Samuel H. Sternberg, Michelle J. Wu, Chantal K. Guegler, Jennifer A. Doudna, William James Greenleaf · 2017 · Proceedings of the National Academy of Sciences
10. Computational approaches for effective CRISPR guide RNA design and evaluation
    Guanqing Liu, Yong Zhang, Tao Zhang · 2019 · Computational and Structural Biotechnology Journal
11. Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system
    Xiaoxi Liu, Ayaka Homma, Jamasb Joshua Sayadi, Shu Yang, Jun Ohashi, Toru Takumi · 2016 · Scientific Reports
12. Efficiency and Inheritance of Targeted Mutagenesis in Maize Using CRISPR-Cas9
    Jinjie Zhu, Ning Song, Silong Sun, Weilong Yang, Haiming Zhao, Weibin Song, Jinsheng Lai · 2015 · Journal of genetics and genomics/Journal of Genetics and Genomics
13. A machine learning approach for predicting CRISPR-Cas9 cleavage efficiencies and patterns underlying its mechanism of action
    Shiran Abadi, Winston X. Yan, David Amar, Itay Mayrose · 2017 · PLoS Computational Biology
14. CRISPR-Cas9: a new and promising player in gene therapy
    Xiao-Jie, Lu, Hui-Ying, Xue, Zun-Ping, Ke, Jin-Lian, Chen, Li-Juan, Ji · 2015 · Journal of Medical Genetics
15. Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway
    Jae Seong Lee, Thomas Beuchert Kallehauge, Lasse Ebdrup Pedersen, Helene Faustrup Kildegaard · 2015 · Scientific Reports
16. Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design
    Justin Smith, Sundari Suresh, Ulrich Schlecht, Manhong Wu, Omar Wagih, Gary Peltz, Ronald Wayne Davis, Lars Michael Steinmetz, Leopold Parts, Robert P. St.Onge · 2016 · Genome biology
17. High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli
    Suhyung Cho, Donghui Choe, Eun‐Ju Lee, Sun Chang Kim, Bernhard Ørn Palsson, Byung‐Kwan Cho · 2018 · ACS Synthetic Biology
18. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
    Daniel Fuentes, Tomek Swigut, Joanna Wysocka · 2018 · eLife
19. Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
    Jennifer L. Gori, Patrick D. Hsu, Morgan L. Maeder, Shen Shen, G. Grant Welstead, David A. Bumcrot · 2015 · Human Gene Therapy
20. Expanding the CRISPR imaging toolset withStaphylococcus aureusCas9 for simultaneous imaging of multiple genomic loci
    Baohui Chen, Jeffrey Hu, Ricardo Almeida, Harrison Liu, Sanjeev Balakrishnan, Christian Covill‐Cooke, Wendell A. Lim, Bo Huang · 2016 · Nucleic Acids Research
21. A genome-scale screen for synthetic drivers of T cell proliferation
    Mateusz Legut, Zoran Z. Gajic, Maria Guarino, Zharko Daniloski, Jahan A. Rahman, Xinhe Xue, Congyi Lu, Lu Lu, Eleni P. Mimitou, Stephanie Hao et al. · 2022 · Nature
22. CRISPR /Cas9‐mediated knockout of Ms1 enables the rapid generation of male‐sterile hexaploid wheat lines for use in hybrid seed production
    Anzu Okada, Taj Arndell, Nikolai V. Borisjuk, Niharika Sharma, Nathan S. Watson‐Haigh, Elise J. Tucker, Ute Baumann, Peter Langridge, Ryan Whitford · 2019 · Plant Biotechnology Journal
23. Evaluating and enhancing target specificity of gene-editing nucleases and deaminases
    Kim, Daesik, Luk, Kevin, Wolfe, Scot A., Kim, Jin-Soo · 2019 · Annual Review of Biochemistry
24. CRISPR/Cas9 Immune System as a Tool for Genome Engineering
    Magdalena Hryhorowicz, Daniel Lipiński, Joanna Zeyland, Ryszard Słomski · 2016 · Archivum Immunologiae et Therapiae Experimentalis
25. A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors
    Lior Izhar, Britt Adamson, Alberto Ciccia, Jedd Lewis, Laura Pontano Vaites, Yumei Leng, Anthony C. T. Liang, Thomas F. Westbrook, J. Wade Harper, Stephen Joseph Elledge · 2015 · Cell Reports
26. Recent Progress in CRISPR/Cas9 Technology
    Yue Mei, Yan Wang, Huiqian Chen, Zhong Sheng Sun, Xing‐Da Ju · 2016 · Journal of genetics and genomics/Journal of Genetics and Genomics
27. The Impact of Chromatin Dynamics on Cas9-Mediated Genome Editing in Human Cells
    René Daer, Josh Cutts, David A. Brafman, Karmella Ann Haynes · 2016 · ACS Synthetic Biology
28. Efficient and Allele-Specific Genome Editing of Disease Loci in Human iPSCs
    Cory J. Smith, Leire Abalde-Atristain, Chaoxia He, Brett R. Brodsky, Evan M. Braunstein, Pooja Chaudhari, Yoon-Young Jang, Linzhao Cheng, Zhaohui Ye · 2014 · Molecular Therapy
29. CRISPR-Cas9D10A nickase-based genotypic and phenotypic screening to enhance genome editing
    Ting-Wei Will Chiang, Carlos le Sage, Delphine Larrieu, Mukerrem Demir, Stephen P. Jackson · 2016 · Scientific Reports
30. Saturation variant interpretation using CRISPR prime editing
    Erwood, Steven, Bily, Teija M. I., Lequyer, Jason, Yan, Joyce, Gulati, Nitya, Brewer, Reid A., Zhou, Liangchi, Pelletier, Laurence, Ivakine, Evgueni A., Cohn, Ronald D. · 2022 · Nature Biotechnology
31. Zebrafish Genome Engineering Using the CRISPR–Cas9 System
    Mingyu Li, Liyuan Zhao, Patrick Page-McCaw, Wenbiao Chen · 2016 · Trends in Genetics
32. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells
    Susan M. Byrne, Luis Ortiz, Prashant Mali, John Aach, George McDonald Church · 2014 · Nucleic Acids Research
33. Genome-wide tracking of dCas9-methyltransferase footprints
    Christina Galonska, Jocelyn Charlton, Alexandra L. Mattei, Julie Donaghey, Kendell Clement, Hongcang Gu, Arman W. Mohammad, Elena K. Stamenova, Davide Cacchiarelli, Sven Klages et al. · 2018 · Nature Communications
34. IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications
    Karen E. Johnson, Virginie Bottero, Stephanie Flaherty, Sujoy Dutta, Vivek Vikram Singh, Bala Chandran · 2014 · PLoS Pathogens
35. Generation of Genomic Deletions in Mammalian Cell Lines via CRISPR/Cas9
    Daniel E. Bauer, Matthew C. Canver, Stuart H. Orkin · 2014 · Journal of Visualized Experiments
36. Targeted activation of diverse CRISPR-Cas systems for mammalian genome editing via proximal CRISPR targeting
    Fuqiang Chen, Xiao Lan Ding, Yongmei Feng, Timothy Seebeck, Yanfang Jiang, Gregory D. Davis · 2017 · Nature Communications
37. CRISPR interference-based specific and efficient gene inactivation in the brain
    Yi Zheng, Wei Shen, Jian Zhang, Bo Yang, Yaonan Liu, Huihui Qi, Xia Yu, Si‐Yao Lu, Yun Chen, Yuzhou Xu et al. · 2018 · Nature Neuroscience
38. Quantifying on- and off-target genome editing
    Ayal Hendel, Eli J. Fine, Gang Bao, Matthew Hebden Porteus · 2015 · Trends in biotechnology
39. Conditional Knockouts Generated by Engineered CRISPR-Cas9 Endonuclease Reveal the Roles of Coronin in C. elegans Neural Development
    Zhongfu Shen, Xianliang Zhang, Yongping Chai, Zhiwen Zhu, Peishan Yi, Guoxin Feng, Wei Li, Guangshuo Ou · 2014 · Developmental Cell
40. Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression
    Aliaksandra Radzisheuskaya, Daria Shlyueva, I. Müller, K. Helin · 2016 · Nucleic Acids Research
41. Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans
    Xiangyang Chen, Fei Xu, Chengming Zhu, Jiaojiao Ji, Xufei Zhou, Xuezhu Feng, Shouhong Guang · 2014 · Scientific Reports
42. CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects
    Karthik Murugan, Arun Somwarpet Seetharam, Andrew Josef Severin, Dipali G. Sashital · 2020 · Journal of Biological Chemistry
43. Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives
    Magdy M. Mahfouz, Agnieszka Piatek, C. Neal Stewart · 2014 · Plant Biotechnology Journal
44. Chromatin accessibility: methods, mechanisms, and biological insights
    Andrés Mansisidor, Viviana I. Risca · 2022 · Nucleus
45. Genome-wide profiling of adenine base editor specificity by EndoV-seq
    Liang, Puping, Xie, Xiaowei, Zhi, Shengyao, Sun, Hongwei, Zhang, Xiya, Chen, Yu, Chen, Yuxi, Xiong, Yuanyan, Ma, Wenbin, Liu, Dan et al. · 2019 · Nature Communications
46. Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9
    Alberto Stolfi, Shashank Gandhi, Farhana Salek, Lionel Christiaen · 2014 · Development
47. CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus
    HyunJun Kang, Petra Minder, Mi Ae Park, Walatta-Tseyon Mesquitta, Bruce Edward Torbett, Igor I. Slukvin · 2015 · Molecular Therapy — Nucleic Acids
48. CRISPR technologies for bacterial systems: Current achievements and future directions
    Kyeong Rok Choi, Sang Yup Lee · 2016 · Biotechnology Advances
49. Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9
    Qingyan Lv, Lin Yuan, Jichao Deng, Mao Chen, Yong Wang, Jian Zeng, Zhanjun Li, Liangxue Lai · 2016 · Scientific Reports
50. Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
    Eric A. Josephs, D. Dewran Koçak, Christopher J. Fitzgibbon, Joshua McMenemy, Charles A. Gersbach, Piotr E. Marszałek · 2015 · Nucleic Acids Research
51. CRISPR-Cas9 for in vivo Gene Therapy: Promise and Hurdles
    Wei-Jing Dai, Liyao Zhu, Zhongyi Yan, Yong Xu, Qilong Wang, Xiaojie Lu · 2016 · Molecular Therapy — Nucleic Acids
52. Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing
    Nicolas Wyvekens, Ved V. Topkar, Cyd Khayter, J. Keith Joung, Shengdar Q. Tsai · 2015 · Human Gene Therapy
53. Probing the impact of chromatin conformation on genome editing tools
    Xiaoyu Chen, Marrit Rinsma, Josephine M. Janssen, Jin Liu, Ignazio Maggio, Manuel A.F.V. Gonçalves · 2016 · Nucleic Acids Research
54. The influence of eukaryotic chromatin state on CRISPR–Cas9 editing efficiencies
    Sebald A. N. Verkuijl, Marianne G. Rots · 2018 · Current Opinion in Biotechnology
55. The chemistry of Cas9 and its CRISPR colleagues
    Janice S. Chen, Jennifer A. Doudna · 2017 · Nature Reviews Chemistry
56. DNA stretching induces Cas9 off-target activity
    Matthew D. Newton, Ben Taylor, Rosalie P.C. Driessen, Leonie Roos, Nevena Cvetešić, Shenaz Allyjaun, Boris Lenhard, Maria Emanuela Cuomo, David Rueda · 2019 · Nature Structural & Molecular Biology
57. In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila
    Shuailiang Lin, Ben Ewen‐Campen, Xiaochun Ni, Benjamin E. Housden, Norbert Perrimon · 2015 · Genetics
58. Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia
    Francis P. Pankowicz, Mercedes Barzi, Xavier D. Legras, Leroy Hubert, Mi Tian, Julie Tomolonis, Milan Ravishankar, Qin Sun, Diane Yang, Malgorzata Borowiak et al. · 2016 · Nature Communications
59. Induced Pluripotent Stem Cells: Reprogramming Platforms and Applications in Cell Replacement Therapy
    Akram Al Abbar, Siew Ching Ngai, Nadine Nograles, Suleiman Yusuf Alhaji, Syahril Abdullah · 2020 · BioResearch open access
60. One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment
    Grav, Lise Marie, Lee, Jae Seong, Gerling, Signe, Kallehauge, Thomas Beuchert, Hansen, Anders Holmgaard, Kol, Stefan, Lee, Gyun Min, Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup · 2015 · Biotechnology Journal
61. Genetic advances in systemic lupus erythematosus: an update
    Lingyan Chen, David Lester Morris, Timothy James Vyse · 2017 · Current Opinion in Rheumatology
62. Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
    Lovorka Stojic, Aaron T. L. Lun, Jasmin Mangei, Patrice Mascalchi, Valentina Quarantotti, Alexis R. Barr, Chris Bakal, John C. Marioni, Fanni V. Gergely, Duncan T. Odom · 2018 · Nucleic Acids Research
63. CRISPR/Cas-based genome engineering in natural product discovery
    Yaojun Tong, Tilmann Weber, Sang Yup Lee · 2018 · Natural Product Reports
64. “Off-Spotter”: very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs
    Venetia Pliatsika, Isidore Rigoutsos · 2015 · Biology Direct
65. Computational Tools and Resources for CRISPR/Cas Genome Editing
    Chao Li, Wen Chu, Rafaqat A. Gill, Shifei Sang, Yuqin Shi, Xuezhi Hu, Yuting Yang, Qamar U. Zaman, Baohong Zhang · 2022 · Genomics Proteomics & Bioinformatics
66. In Silico Meets In Vivo : Towards Computational CRISPR-Based sgRNA Design
    Guohui Chuai, Qilong Wang, Qi Liu · 2016 · Trends in biotechnology
67. Modulating chromatin accessibility by transactivation and targeting proximal dsgRNAs enhances Cas9 editing efficiency in vivo
    Guanwen Liu, Kangquan Yin, Qianwei Zhang, Caixia Gao, Jin‐Long Qiu · 2019 · Genome biology
68. Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
    Lauren R. Polstein, Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley, Peggy J. Bledsoe, Lingyun Song, Alexias Safi, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach · 2015 · Genome Research
69. CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine
    Filipe V. Jacinto, Wolfgang Link, Bibiana I. Ferreira · 2020 · Journal of Cellular and Molecular Medicine
70. The Current State and Future of CRISPR-Cas9 gRNA Design Tools
    Laurence O. W. Wilson, Aidan R. O’Brien, Denis C. Bauer · 2018 · Frontiers in Pharmacology
71. Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage
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72. Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing
    Ciaran M. Lee, Thomas James Cradick, Eli J. Fine, Gang Bao · 2016 · Molecular Therapy
73. CRISPR/Cas9-mediated noncoding RNA editing in human cancers
    Jie Yang, Xiaodan Meng, Jinchang Pan, Nan Jiang, Chengwei Zhou, Zhenhua Wu, Zhaohui Gong · 2017 · RNA Biology
74. Genome editing by natural and engineered CRISPR-associated nucleases
    Wen Y. Wu, Joyce H.G. Lebbink, Roland Kanaar, Niels Geijsen, John van der OOST · 2018 · Nature Chemical Biology
75. A new age in functional genomics using CRISPR/Cas9 in arrayed library screening
    Alexander Agrotis, Robin Ketteler · 2015 · Frontiers in Genetics
76. In Vitro Enzymology of Cas9
    Carolin Anders, Martin Jínek · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
77. CRISPR/Cas9 gene drives in genetically variable and nonrandomly mating wild populations
    Douglas W. Drury, Amy L. Dapper, Dylan J. Siniard, Gabriel E. Zentner, Michael J. Wade · 2017 · Science Advances
78. The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies
    Ralph W. N. Slijkerman, Fei Song, Galuh Astuti, Martijn A. Huynen, Erwin van Wijk, Knut Stieger, Rob W.J. Collin · 2015 · Progress in Retinal and Eye Research
79. Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
    Youngbin Lim, So Young Bak, Keewon Sung, Euihwan Jeong, Seung Hwan Lee, Jin‐Soo Kim, Sangsu Bae, Seong Keun Kim · 2016 · Nature Communications
80. CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects
    Zhao Zhang, Yuelin Zhang, Fei Gao, Shuo Han, Kathryn S.E. Cheah, Hung‐Fat Tse, Qizhou Lian · 2017 · Molecular Therapy — Nucleic Acids
81. Hybridization Kinetics Explains CRISPR-Cas Off-Targeting Rules
    Misha Klein, Behrouz Eslami-Mossallam, Dylan Gonzalez Arroyo, Martin Depken · 2018 · Cell Reports
82. Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes
    A. Vigouroux, Enno Rainer Oldewurtel, Lun Cui, Sven van Teeffelen, David Bikard · 2018 · Molecular Systems Biology
83. Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases
    Lin Lin, Yong Liu, Fengping Xu, Jinrong Huang, Tina Fuglsang Daugaard, Trine Skov Petersen, Bettina Dencker Hansen, Lingfei Ye, Qing Xiao Zhou, Fang Fang et al. · 2018 · GigaScience
84. Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing
    Charlene Babra Waryah, Colette Moses, Mahira Arooj, Pilar Blancafort · 2018 · Methods in molecular biology
85. Targeted mutagenesis using the Agrobacterium tumefaciens-mediated CRISPR-Cas9 system in common wheat
    Shujuan Zhang, Rongzhi Zhang, Guoqi Song, Jie Gao, Wěi Li, Xiaodong Han, Mingli Chen, Yulian Li, Genying Li · 2018 · BMC Plant Biology
86. Regulation of gene expression by altered promoter methylation using a CRISPR/Cas9-mediated epigenetic editing system
    Jeong Gu Kang, Jin Suk Park, Jeong-Heosn Ko, Yong-Sam Kim · 2019 · Scientific Reports
87. CRISPR/Cas9-mediated genome engineering of CHO cell factories: application and perspectives
    Lee, Jae Seong, Grav, Lise Marie, Lewis, Nathan E., Faustrup Kildegaard, Helene · 2015 · Biotechnology Journal
88. Precision cancer mouse models through genome editing with CRISPR-Cas9
    Haiwei Mou, Zachary Kennedy, Daniel G. Anderson, Hao Yin, Wen Xue · 2015 · Genome Medicine
89. Nucleosomes Inhibit Cas9 Endonuclease Activity in Vitro
    John M. Hinz, Marian F. Laughery, John J. Wyrick · 2015 · Biochemistry
90. Tools for experimental and computational analyses of off-target editing by programmable nucleases
    Bao, X. Robert, Pan, Yidan, Lee, Ciaran M., Davis, Timothy H., Bao, Gang · 2021 · Nature Protocols
91. How specific is CRISPR/Cas9 really?
    Henriette O’Geen, Abigail S. Yu, David Jay Segal · 2015 · Current Opinion in Chemical Biology
92. Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery
    Mehmet Fatih Bolukbasi, Ankit Gupta, Scot A. Wolfe · 2015 · Nature Methods
93. A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
    Iman Farasat, Howard M. Salis · 2016 · PLoS Computational Biology
94. CRISPR-mediated Activation of Latent HIV-1 Expression
    Prajit Limsirichai, Thomas Gaj, David V. Schaffer · 2015 · Molecular Therapy
95. A glance at genome editing with CRISPR–Cas9 technology
    Antara Barman, Bornali Deb, Supriyo Chakraborty · 2019 · Current Genetics
96. DIG-Seq: A genome-wide CRISPR off-target profiling method using chromatin DNA
    Kim, Daesik, Kim, Jin-Soo · 2018 · Genome Research
97. Human induced pluripotent stem cells as a platform for personalized and precision cardiovascular medicine
    Matsa, Elena, Ahrens, John H., Wu, Joseph C. · 2016 · Physiological Reviews
98. Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution
    Anna F. Gilles, Michalis Averof · 2014 · EvoDevo
99. Efficient Genome Editing in the Oomycete Phytophthora sojae Using CRISPR/Cas9
    Yufeng “Francis” Fang, Linkai Cui, Biao Gu, Felipe D. Arredondo, Brett M. Tyler · 2017 · Current Protocols in Microbiology
100. Optimizing genome editing strategy by primer-extension-mediated sequencing
     Jianhang Yin, Mengzhu Liu, Yang Liu, Jinchun Wu, Tingting Gan, Weiwei Zhang, Yinghui Li, Yaxuan Zhou, Jiazhi Hu · 2019 · Cell Discovery