Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

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The new frontier of genome engineering with CRISPR-Cas9

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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

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Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

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Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

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Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

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Genome Engineering With Zinc-Finger Nucleases

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MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

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Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

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Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

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Targeted genome editing in human repopulating haematopoietic stem cells

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Fok I dimerization is required for DNA cleavage

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High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

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Cas9 specifies functional viral targets during CRISPR–Cas adaptation

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Determining kinetics and affinities of protein interactions using a parallel real-time label-free biosensor, the Octet

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Optimization of scarless human stem cell genome editing

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Dynamics of CRISPR-Cas9 genome interrogation in living cells

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Chromatin Immunoprecipitation for Determining the Association of Proteins with Specific Genomic Sequences In Vivo

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CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems

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Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair

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In Vitro Enzymology of Cas9

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Conservative Repair of a Chromosomal Double-Strand Break by Single-Strand DNA through Two Steps of Annealing

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Genome Editing Using Cas9 Nickases

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In Vitro Assessment of Zinc Finger Nuclease Activity

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Cas9 RNP nucleofection for cell lines using Lonza 4D Nucleofector v1Preprint

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CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

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CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

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Correction of a pathogenic gene mutation in human embryos

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Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

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Advances in the delivery of RNA therapeutics: from concept to clinical reality

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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex

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Past, present, and future of CRISPR genome editing technologies

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Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations

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Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq

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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

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A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9

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Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning

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Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

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Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing

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Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing

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Precision genome editing using cytosine and adenine base editors in mammalian cells

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Bispecific antibodies targeting mutant <i>RAS</i> neoantigens

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In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human disease

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Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing

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Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models

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Customizing the genome as therapy for the β-hemoglobinopathies.

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Current Strategies for Increasing Knock-In Efficiency in CRISPR/Cas9-Based Approaches

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Genetic medicines for CF: Hype versus reality

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Emerging applications of gene editing technologies for the development of climate-resilient crops

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A Mixed Culture of Bacterial Cells Enables an Economic DNA Storage on a Large Scale

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WDR41 supports lysosomal response to changes in amino acid availability

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Design of efficacious somatic cell genome editing strategies for recessive and polygenic diseases

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Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing

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Editing Aspergillus terreus using the CRISPR-Cas9 system

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Increasing the efficiency of CRISPR‐Cas9‐VQR precise genome editing in rice

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Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

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CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery

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