ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
Jazayeri, Ali, Falck, Jacob, Lukas, Claudia, Bartek, Jiri, Smith, Graeme C. M., Lukas, Jiri, Jackson, Stephen P.·2006·Nature Cell Biology
DOI 10.1038/ncb1337
Cited by (1,000)
Items 301–400 of 1,000
- Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1Lin Feng, Nan Li, Yujing Li, Jiadong Wang, Min Gao, Wenqi Wang, Junjie Chen · 2015 · Cell Discovery
- Regulators of homologous recombination repair as novel targets for cancer treatmentMałgorzata Krajewska, Rudolf S.N. Fehrmann, Elisabeth G.E. de Vries, Marcel A.T.M. van Vugt · 2015 · Frontiers in Genetics
- Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapiesTheodora Mantso, George Goussetis, Rodrigo Franco, Sotiris Botaitis, Aglaia Pappa, Mihalis I. Panayiotidis · 2016 · Seminars in Cancer Biology
- ATR maintains select progenitors during nervous system developmentYoungsoo Lee, Erin R.P. Shull, Pierre‐Olivier Frappart, Sachin Katyal, Vanessa D. Enriquez-Rios, Jingfeng Zhao, Helen R Russell, Eric J. Brown, Peter J. McKinnon · 2012 · The EMBO Journal
- Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2Naihan Xu, Nadia Hégarat, Elizabeth J. Black, Mary T. Scott, Helfrid Hochegger, David A. Gillespie · 2010 · The Journal of Cell Biology
- A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiationValentine, Jane M, Kumar, Sonia, Moumen, Abdeladim · 2011 · BMC Cancer
- CDK6 protects epithelial ovarian cancer from platinum‐induced death via FOXO3 regulationAlessandra Dall’Acqua, Maura Sonego, Ilenia Pellizzari, Ilenia Pellarin, Vincenzo Canzonieri, Sara D’Andrea, Sara Benevol, Roberto Sorio, Giorgio Giorda, Daniela Califano et al. · 2017 · EMBO Molecular Medicine
- Persistent repair intermediates induce senescenceFemke M. Feringa, Jonne A. Raaijmakers, Michael A. Hadders, Chantal Vaarting, Libor Macůrek, Luuk S. Heitink, Lenno Krenning, René H. Medema · 2018 · Nature Communications
- Saturated Fatty Acids Modulate Cell Response to DNA Damage: Implication for Their Role in TumorigenesisLi Zeng, Guangzhi Wu, Kim Jee Goh, Yew Mun Lee, Chuo Chung Ng, Ang Ben You, Jianhe Wang, Deyong Jia, Aijun Hao, Qiang Yu et al. · 2008 · PLoS ONE
- Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycleVanessa Oakes, Weili Wang, Brittney S. Harrington, Won Jae Lee, Heather Beamish, Kee Ming Chia, Alex Pinder, Hidemasa Goto, Masaki Inagaki, Sandra J. Pavey et al. · 2014 · Cell Cycle
- Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicksLianne E. M. Vriend, Rohit Prakash, Chun-Chin Chen, Fabio Vanoli, Francesca Cavallo, Yu Zhang, Maria Jasin, Przemek M. Krawczyk · 2016 · Nucleic Acids Research
- The Response to DNA Damage at Telomeric Repeats and Its Consequences for Telomere FunctionYlli Doksani · 2019 · Genes
- WRN Is Required for ATM Activation and the S-Phase Checkpoint in Response to Interstrand Cross-Link–Induced DNA Double-Strand BreaksWen‐Hsing Cheng, Diana Muftic, Meltem Müftüoğlu, Lale Dawut, Christa Morris, Thomas Helleday, Yosef Shiloh, Vilhelm A. Bohr · 2008 · Molecular Biology of the Cell
- DNA double‐strand break response in stem cells: Mechanisms to maintain genomic integrityPratik K. Nagaria, Carine Robert, Feyruz Virgilia Rassool · 2012 · Biochimica et Biophysica Acta (BBA) - General Subjects
- An ATR- and BRCA1-Mediated Fanconi Anemia Pathway Is Required for Activating the G2/M Checkpoint and DNA Damage Repair upon RereplicationWenge Zhu, Anindya Dutta · 2006 · Molecular and Cellular Biology
- APC/CCdh1 controls CtIP stability during the cell cycle and in response to DNA damageLorenzo Lafranchi, H. Rudolf de Boer, Elisabeth G.E. de Vries, Shao‐En Ong, Alessandro A. Sartori, Marcel A.T.M. van Vugt · 2014 · The EMBO Journal
- BTK Modulates p53 Activity to Enhance Apoptotic and Senescent ResponsesMohammad Althubiti, Miran Rada, Jesvin Samuel, Josep M. Escorsa, Hishyar Najeeb, Koon-Guan Lee, Kong‐Peng Lam, George D.D. Jones, Nickolai A. Barlev, Salvador Macip · 2016 · Cancer Research
- ATM and ATR signaling at a glancePoorwa Awasthi, Marco Foiani, Amit Kumar · 2016 · Journal of Cell Science
- Nek1 kinase associates with ATR–ATRIP and primes ATR for efficient DNA damage signalingShizhou Liu, Chu Kwen Ho, Jian Ouyang, Lee Zou · 2013 · Proceedings of the National Academy of Sciences
- Dancing on Damaged Chromatin: Functions of ATM and the RAD50/MRE11/NBS1 Complex in Cellular Responses to DNA DamageKenta Iijima, Maki Ohara, Ryota Seki, Hiroshi Tauchi · 2008 · Journal of Radiation Research
- Overexpression of Sp1 leads to p53‐dependent apoptosis in cancer cellsJian‐Ying Chuang, Chien‐Hsing Wu, Ming‐Derg Lai, Wen‐Chang Chang, Jan‐Jong Hung · 2009 · International Journal of Cancer
- Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiationPetra Groth, Manuel Luís Orta, Ingegerd Elvers, Muntasir Mamun Majumder, Anne Lagerqvist, Thomas Helleday · 2012 · Nucleic Acids Research
- The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATMHae Yong Yoo, Akiko Kumagai, Anna Shevchenko, Andrej Shevchenko, William G. Dunphy · 2009 · Molecular Biology of the Cell
- Regulation of the DNA Damage Response by Cyclin-Dependent KinasesCamilla Trovesi, Nicola Manfrini, Marco Falcettoni, Maria Pia Longhese · 2013 · Journal of Molecular Biology
- Sequential Combination Therapy of CDK Inhibition and Doxorubicin Is Synthetically Lethal in p53-Mutant Triple-Negative Breast CancerNatalie A. Jabbour-Leung, Xian Chen, Tuyen N. Bui, Yufeng Jiang, Dong Yang, Smruthi Vijayaraghavan, Mark J. McArthur, Kelly K. Hunt, Khandan Keyomarsi · 2016 · Molecular Cancer Therapeutics
- PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage responseLiang Xie, Xinchun Pi, Ashutosh Mishra, Guo‐Hua Fong, Junmin Peng, Cam Patterson · 2012 · Journal of Clinical Investigation
- ATR signaling at a glanceBunsyo Shiotani, Lee Zou · 2009 · Journal of Cell Science
- The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylationGuangjian Fan, Lianhui Sun, Ling Hua Meng, Hu Chen, Xing Wang, Zhan Shi, Congli Hu, Yang Han, Qingqing Yang, Liu Cao et al. · 2021 · Nature Communications
- Cellular senescence: a hitchhiker’s guideAloysious Dominic Aravinthan · 2015 · Human Cell
- CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiationArne Nedergaard Kousholt, Kasper Fugger, Saskia Hoffmann, Brian Daniel Larsen, Tobias Menzel, Alessandro A. Sartori, Claus Storgaard Sørensen · 2012 · The Journal of Cell Biology
- RPA Mediates Recombination Repair During Replication Stress and Is Displaced from DNA by Checkpoint Signalling in Human CellsKate M. Sleeth, Claus Storgaard Sørensen, Natalia Issaeva, Jaroslaw Dziegielewski, Jiří Bártek, Thomas Helleday · 2007 · Journal of Molecular Biology
- Targeting Wee1 kinase as a therapeutic approach in Hematological MalignanciesSajjad Vakili‐Samiani, Abduladheem Turki Jalil, Walid Kamal Abdelbasset, Alexei Valerievich Yumashev, Vahid Karpisheh, Pooya Jalali, Sara Adibfar, Majid Ahmadi, Abbas Ali Hosseinpour Feizi, Farhad Jadidi‐Niaragh · 2021 · DNA repair
- SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathwayChing-Shyi Peter Wu, Jian Ouyang, Eiichiro Mori, Hai Dang Nguyen, Alexandre Maréchal, Alexander Hallet, David J. Chen, Lee Zou · 2014 · Genes & Development
- Keeping checkpoint kinases in line: new selective inhibitors in clinical trialsSusan Ashwell, James W. Janetka, Sonya Z abludoff · 2008 · Expert Opinion on Investigational Drugs
- DNA Structure and Integrity Checkpoints during the Cell Cycle and Their Role in Drug Targeting and Sensitivity of Tumor Cells to Anticancer TreatmentAndrzej Składanowski, Przemyslaw M. Bozko, Michał Sabisz · 2009 · Chemical Reviews
- Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis Are Required for Genomic StabilityLaura L. Pontano, Priya Aggarwal, Olena Barbash, Eric J. Brown, Craig H. Bassing, John Alan Diehl · 2008 · Molecular and Cellular Biology
- Bclaf1 is an important NF-κB signaling transducer and C/EBPβ regulator in DNA damage-induced senescenceA-w Shao, Hui Sun, Yunyun Geng, Q Peng, Peigang Wang, Jingxian Chen, Tao Xiong, Runmeng Cao, Jun Tang · 2016 · Cell Death and Differentiation
- Rad17 Plays a Central Role in Establishment of the Interaction between TopBP1 and the Rad9-Hus1-Rad1 Complex at Stalled Replication ForksJoon Lee, William G. Dunphy · 2010 · Molecular Biology of the Cell
- Wee1 Kinase: A Potential Target to Overcome Tumor Resistance to TherapyFrancesca Esposito, Raffaella Giuffrida, Gabriele Raciti, Caterina Puglisi, Stefano Forte · 2021 · International Journal of Molecular Sciences
- ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damageArmin M. Gamper, Reza Rofougaran, Simon C. Watkins, Joel S. Greenberger, Jan Hendrik Beumer, Christopher J. Bakkenist · 2013 · Nucleic Acids Research
- MCL-1 localizes to sites of DNA damage and regulates DNA damage responseSarwat Jamil, Cezar Stoica, Tillie‐Louise Hackett, Vincent Duronio · 2010 · Cell Cycle
- The Checkpoint Kinase 1 Inhibitor Prexasertib Induces Regression of Preclinical Models of Human NeuroblastomaCaitlin D. Lowery, Alle B. VanWye, Michele S. Dowless, Wayne D. Blosser, Beverly L. Falcón, Julie A. Stewart, Jennifer Rachelle Stephens, Richard Paul Beckmann, Aimee K. Bence, Louis F. Stancato · 2017 · Clinical Cancer Research
- Cell Signaling Pathways That Promote Radioresistance of Cancer CellsMichel M. Ouellette, Sumin Zhou, Ying Yan · 2022 · Diagnostics
- Bridging the gap between in vitro and in vivo: Dose and schedule predictions for the ATR inhibitor AZD6738Stephen Checkley, Linda MacCallum, James W.T. Yates, Paul Jasper, Haobin Luo, John Tolsma, Claus Bendtsen · 2015 · Scientific Reports
- Inhibiting homologous recombination for cancer therapySophia B. Chernikova, John C. Game, J. Martin Brown · 2012 · Cancer Biology & Therapy
- Serine/threonine phosphatases in the DNA damage response and cancerA Peng, James L. Maller · 2010 · Oncogene
- The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forksJoon Lee, William G. Dunphy · 2013 · Molecular Biology of the Cell
- DNA-dependent Protein Kinase Regulates DNA End Resection in Concert with Mre11-Rad50-Nbs1 (MRN) and Ataxia Telangiectasia-mutated (ATM)Yi Zhou, Tanya T. Paull · 2013 · Journal of Biological Chemistry
- Pot1 and cell cycle progression cooperate in telomere length regulationChurikov, Dmitri, Price, Carolyn M · 2008 · Nature Structural & Molecular Biology
- DNA damage repair: anytime, anywhere?Essers, Jeroen, Vermeulen, Wim, Houtsmuller, Adriaan B · 2006 · Current Opinion in Cell Biology
- Mec1/ATR regulates the generation of single‐stranded DNA that attenuates Tel1/ATM signaling at DNA endsMichela Clerici, Camilla Trovesi, Alessandro Galbiati, Giovanna Lucchini, Maria Pia Longhese · 2013 · The EMBO Journal
- Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phaseEmil Mladenov, Xiaoxiang Fan, Rositsa Dueva, Aashish Soni, George E. Iliakis · 2019 · Scientific Reports
- The involvement of ataxia-telangiectasia mutated protein activation in nucleotide excision repair-facilitated cell survival with cisplatin treatmentColton, Stephanie L., Xu, Xiaoxin S., Wang, Y. Alan, Wang, Gan · 2006 · Journal of Biological Chemistry
- Transient ATM Kinase Inhibition Disrupts DNA Damage–Induced Sister Chromatid ExchangeWhite, Jason S., Choi, Serah, Bakkenist, Christopher J. · 2010 · Science Signaling
- Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatmentLindsey M. Jackson, George‐Lucian Moldovan · 2022 · NAR Cancer
- Cyclin-Dependent Kinase 2–Dependent Phosphorylation of ATRIP Regulates the G2-M Checkpoint Response to DNA DamageJeremy S. Myers, Runxiang Zhao, Xin Xu, Amy‐Joan L. Ham, David Cortez · 2007 · Cancer Research
- ATM- and ATR-Mediated Phosphorylation of XRCC3 Regulates DNA Double-Strand Break-Induced Checkpoint Activation and RepairKumar Somyajit, Shivakumar Basavaraju, Ralph Scully, Ganesh Nagaraju · 2013 · Molecular and Cellular Biology
- High resolution imaging of changes in the structure and spatial organization of chromatin, γ-H2A.X and the MRN complex within etoposide-induced DNA repair fociGraham Dellaire, Rosemarie Kepkay, David P. Bazett‐Jones · 2009 · Cell Cycle
- ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNAHui Zhang, PamelaSara E. Head, Waaqo B. Daddacha, Seong‐Hoon Park, Xingzhe Li, Yunfeng Pan, Matthew Z. Madden, Duc Minh Duong, Maohua Xie, Bing Yu et al. · 2016 · Cell Reports
- Integrating DNA damage repair with the cell cycleJohanne M. Murray, Antony M. Carr · 2018 · Current Opinion in Cell Biology
- Aurora‐A expressing tumour cells are deficient for homology‐directed DNA double strand‐break repair and sensitive to PARP inhibitionTony Sourisseau, Despina Maniotis, Afshan McCarthy, Chan Tang, Christopher J. Lord, Alan Ashworth, Spiros Linardopoulos · 2010 · EMBO Molecular Medicine
- Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cellsYu Wang, Qiao Liu, Zhaojian Liu, Boxuan Li, Zhao-Liang Sun, Haibin Zhou, Xiyu Zhang, Yaoqin Gong, Changshun Shao · 2012 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- ATR mediates cisplatin resistance in a p53 genotype-specific mannerNiquiche Sangster‐Guity, Bogdan Conrad, N Papadopoulos, Fred Bunz · 2011 · Oncogene
- The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeastKarine Dubrana, Haico van Attikum, Florence Hediger, Susan M. Gasser · 2007 · Journal of Cell Science
- Inhibition of checkpoint kinase 1 abrogates G2/M checkpoint activation and promotes apoptosis under heat stressYukihiro Furusawa, Takashi Iizumi, Yoshisada Fujiwara, Qing‐Li Zhao, Yoshiaki Tabuchi, Takaharu Nomura, Takashi Kondo · 2011 · APOPTOSIS
- ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repairChun-Chin Chen, Elizabeth M. Kass, Wei-Feng Yen, Thomas Ludwig, Mary Ellen Moynahan, Jayanta Chaudhuri, Maria Jasin · 2017 · Proceedings of the National Academy of Sciences
- RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to RadiotherapyWenjing Liu, Min Zheng, Rou Zhang, Qiuyun Jiang, Guangshi Du, Yingying Wu, Chuanyu Yang, Fubing Li, Wei Li, Luzhen Wang et al. · 2022 · Advanced Science
- Behind the wheel and under the hood: Functions of cyclin-dependent kinases in response to DNA damageLara Wohlbold, Robert P. Fisher · 2009 · DNA repair
- Interplay between ATM and ATR in the regulation of common fragile site stabilityEfrat Ozeri-Galai, Michal Schwartz, A Rahat, Batsheva Kerem · 2007 · Oncogene
- Resilient and resourceful: Genome maintenance strategies in hematopoietic stem cellsSietske T. Bakker, Emmanuelle A. Passegue · 2013 · Experimental Hematology
- Recovery from a DNA‐damage‐induced G2 arrest requires Cdk‐dependent activation of FoxM1Mónica Álvarez‐Fernández, Vincentius A. Halim, Lenno Krenning, Melinda Aprelia, Shabaz Mohammed, Albert J. R. Heck, René H. Medema · 2010 · EMBO Reports
- Genes Regulating Spermatogenesis and Sperm Function Associated With Rare DisordersEmma Linn, Lillian Ghanem, Hanisha Bhakta, Cory Greer, Matteo Avella · 2021 · Frontiers in Cell and Developmental Biology
- Regulation of the Life Cycle of HPVs by Differentiation and the DNA Damage ResponseShiyuan Hong, Laimonis A. Laimins · 2013 · Future Microbiology
- Persistent activation of DNA damage signaling in response to complex mixtures of PAHs in air particulate matterIan W. H. Jarvis, Christoffer Bergvall, Matteo Bottai, Roger N. Westerholm, Ulla Stenius, Kristian Dreij · 2012 · Toxicology and Applied Pharmacology
- Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O‐GlcNAc in the DNA damage response pathwayJun Zhong, Marissa R. Martinez, Srona Sengupta, Albert Lee, Xinyan Wu, Raghothama Chaerkady, Aditi Chatterjee, Robert N. O’Meally, Robert Norman Cole, Akhilesh Pandey et al. · 2014 · PROTEOMICS
- Chromatin dynamics during repair of chromosomal DNA double-strand breaksManisha Sinha, Craig L. Peterson · 2009 · Epigenomics
- Inhibition of ATM kinase activity does not phenocopy ATM protein disruptionSerah Choi, Armin M. Gamper, Jason Scott White, Christopher J. Bakkenist · 2010 · Cell Cycle
- Sonic Hedgehog signaling impairs ionizing radiation–induced checkpoint activation and induces genomic instabilityJennifer M. Leonard, Hong Ye, Cynthia Wetmore, Larry M. Karnitz · 2008 · The Journal of Cell Biology
- A Mutant Allele ofMRE11Found in Mismatch Repair-deficient Tumor Cells Suppresses the Cellular Response to DNA Replication Fork Stress in a Dominant Negative MannerQin Wen, Jennifer Scorah, Geraldine A. Phear, Gary R. Rodgers, Sheila Rodgers, Mark Meuth · 2008 · Molecular Biology of the Cell
- Interplay between the DNA Damage Proteins MDC1 and ATM in the Regulation of the Spindle Assembly CheckpointYifat Eliezer, Liron Argaman, Maya Kornowski, Maayan Roniger, Michal Goldberg · 2014 · Journal of Biological Chemistry
- Structural and functional analysis of the Crb2–BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repairMairi Louise Kilkenny, Andrew S. Doré, Stephen Mark Roe, Konstantinos Nestoras, Jenny Chung-Yee Ho, Felicity Z. Watts, Laurence H. Pearl · 2008 · Genes & Development
- An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63Eloise Smith, Donniphat Dejsuphong, Alessia Balestrini, Martin Hampel, Christof Lenz, Shunichi Takeda, Alessandro Vindigni, Vincenzo Costanzo · 2009 · Nature Cell Biology
- Similarities and differences between “uncapped” telomeres and DNA double-strand breaksJames M. Dewar, David A. Lydall · 2011 · Chromosoma
- Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human CellsLara Wohlbold, Karl A. Merrick, Saurav De, Ramon Amat, Jun Hyun Kim, Stéphane Larochelle, Jasmina J. Allen, Chao Zhang, Kevan M. Shokat, John H.J. Petrini et al. · 2012 · PLoS Genetics
- MRE11–RAD50–NBS1 is a critical regulator of FANCD2 stability and function during DNA double‐strand break repairCéline Lopez‐Roques, Yan Coulombe, Mathieu Delannoy, Julien Vignard, Simona Grossi, Isabelle Brodeur, Amélie Rodrigue, Jean Gautier, Alicja Z. Stasiak, Andrzej Stasiak et al. · 2009 · The EMBO Journal
- Overall Cdk activity modulates the DNA damage response in mammalian cellsAntonio Cerqueira, David Santamarı́a, Bárbara Martínez-Pastor, Myriam Cuadrado, Óscar Fernández-Capetillo, Mariano Barbacid · 2009 · The Journal of Cell Biology
- The shelterin complex and hematopoiesisMorgan Jones, Kamlesh Kumar Bisht, Sharon A. Savage, Jayakrishnan Nandakumar, Catherine E. Keegan, Ivan P. Maillard · 2016 · Journal of Clinical Investigation
- DNA folds threaten genetic stability and can be leveraged for chemotherapyJoanna Zell, Francesco Rota Sperti, Sébastien Britton, David Monchaud · 2020 · RSC Chemical Biology
- The RING Finger Protein RNF8 Ubiquitinates Nbs1 to Promote DNA Double-strand Break Repair by Homologous RecombinationChi-Sheng Lu, Lan N. Truong, Aaron Aslanian, Linda Zhixia Shi, Yongjiang Li, Patty Yi-Hwa Hwang, Kwi Hye Koh, Tony R. Hunter, John R. Yates, Michael W. Berns et al. · 2012 · Journal of Biological Chemistry
- Replication Checkpoint: Tuning and Coordination of Replication Forks in S PhaseNicole Hustedt, Susan M. Gasser, Kenji Shimada · 2013 · Genes
- Identification of a Bis-guanylhydrazone [4,4′-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a Novel Chemotype for Inhibition of Chk2 KinaseAndrew G. Jobson, John H. Cardellina, Dominic A. Scudiero, Sudhir B. Kondapaka, Hongliang Zhang, Hijoo Kim, Robert H. Shoemaker, Yves G. Pommier · 2007 · Molecular Pharmacology
- Cancer cells that survive checkpoint adaptation contain micronuclei that harbor damaged DNACody Wayne Lewis, Roy M. Golsteyn · 2016 · Cell Cycle
- Characterization, Detection, and Treatment Approaches for Homologous Recombination Deficiency in CancerGrainne Mary O'Kane, Ashton Anthony Connor, Steve Gallinger · 2017 · Trends in Molecular Medicine
- Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy EfficacyZhipeng Hong, Tao Liu, Lingfeng Wan, Pengyan Fa, Pankaj Kumar, Yanan Cao, Chandra Bhushan Prasad, Zhaojun Qiu, Joseph Liu, Hongbing Wang et al. · 2022 · Cancer Research
- Elevated Cyclin G2 Expression Intersects with DNA Damage Checkpoint Signaling and Is Required for a Potent G2/M Checkpoint Arrest Response to DoxorubicinMaike Zimmermann, Aruni S. Arachchige Don, Michaela S. Donaldson, Robert Francis Dallapiazza, Colleen E. Cowan, Mary C. Horne · 2012 · Journal of Biological Chemistry
- Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNACarolyn M. George, Eric Alani · 2012 · Critical Reviews in Biochemistry and Molecular Biology
- HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?Giuseppe Nunnari, Johanna A. Smith, René Daniel · 2008 · Journal of Experimental & Clinical Cancer Research
- ATR-Chk1 activation mitigates replication stress caused by mismatch repair-dependent processing of DNA damageDipika Gupta, Bo Lin, Ann E. Cowan, Christopher D. Heinen · 2018 · Proceedings of the National Academy of Sciences
- Cellular Stress and General Pathological ProcessesEugeny Yu. Gusev, Natalia V. Zotova · 2019 · Current Pharmaceutical Design
- Emerging links between the biological clock and the DNA damage responseSpencer James Collis, Simon J. Boulton · 2007 · Chromosoma