ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Zou, L., & Elledge, S. J. (2003) · Science · doi:10.1126/science.1083430 · Cited by 2,693

ATM and related protein kinases: safeguarding genome integrity

Shiloh, Y. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1011 · Cited by 2,577

Cell cycle checkpoint signaling through the ATM and ATR kinases

Abraham, R. T. (2001) · Genes & Development · doi:10.1101/gad.914401 · Cited by 1,966

Chk1 is an essential kinase that is regulated by Atr and required for the G 2 /M DNA damage checkpoint

Liu, Q., Guntuku, S., Cui, X.-S., Matsuoka, S., Cortez, D., Tamai, K., Luo, G., Carattini-Rivera, S., DeMayo, F., Bradley, A., et al. (2000) · Genes & Development · doi:10.1101/gad.14.12.1448 · Cited by 1,625

Chk1 and Chk2 kinases in checkpoint control and cancer

Bartek, J., & Lukas, J. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00110-7 · Cited by 1,513

ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Lee, J.-H., & Paull, T. T. (2005) · Science · doi:10.1126/science.1108297 · Cited by 1,424

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Falck, J., Coates, J., & Jackson, S. P. (2005) · Nature · doi:10.1038/nature03442 · Cited by 1,304

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

Hickson, I., Zhao, Y., Richardson, C. J., Green, S. J., Martin, N. M. B., Orr, A. I., Reaper, P. M., Jackson, S. P., Curtin, N. J., & Smith, G. C. M. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-2727 · Cited by 1,220

Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle

Rothkamm, K., Krüger, I., Thompson, L. H., & Lübrich, M. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.16.5706-5715.2003 · Cited by 1,187

ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Zhao, H., & Piwnica-Worms, H. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.13.4129-4139.2001 · Cited by 1,091

Novel modulators of p53-signaling encoded by unknown genes of emerging viruses

Alzhanova, D. V., Corcoran, K., Bailey, A., Long, K. M., Taft-Benz, S., Graham, R. L., Broussard, G. S., Heise, M. T., Neumann, G., Halfmann, P., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009033 · Cited by 17

CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts

Ramírez-Lugo, J. S., Yoo, H. Y., Yoon, S. J., & Dunphy, W. G. (2011) · Cell Cycle · doi:10.4161/cc.10.3.14711 · Cited by 18

A Point Mutation in theAspergillus nidulans sonBNup98 Nuclear Pore Complex Gene Causes Conditional DNA Damage Sensitivity

Souza, C. P. C. D., Hashmi, S. B., Horn, K. P., & Osmani, S. A. (2006) · Genetics · doi:10.1534/genetics.106.063438 · Cited by 17

5-FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53-mutated colon cancer cells

Akasaka, T., Tsujii, M., Kondo, J., Hayashi, Y., YING, J., Lu, Y., Kato, M., Yamada, T., Yamamoto, S., Inoue, T., et al. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2693 · Cited by 17

Checkpoint kinase phosphorylation in response to endogenous oxidative DNA damage in repair-deficient stationary-phase Saccharomyces cerevisiae

Pawar, V., Liu, J., Patel, N., Kaur, N., Doetsch, P. W., Shadel, G. S., Zhang, H., & Siede, W. (2009) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2009.06.002 · Cited by 17

Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response

Ragland, R. L., Arlt, M. F., Hughes, E. D., Saunders, T. L., & Glover, T. W. (2009) · Mammalian Genome · doi:10.1007/s00335-009-9195-4 · Cited by 17

Damage‐induced reactivation of cohesin in postreplicative DNA repair

Ball, A. R., & Yokomori, K. (2007) · BioEssays · doi:10.1002/bies.20691 · Cited by 17

Regulation of non-homologous end joining via post-translational modifications of components of the ligation step

Durdíková, K., & Chovanec, M. (2016) · Current Genetics · doi:10.1007/s00294-016-0670-7 · Cited by 16

Targeting WEE1 Kinase in Gynecological Malignancies

Zhang, W., Li, Q., & Yin, R. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s462056 · Cited by 16

A Kinase-Independent Role for the Rad3ATR-Rad26ATRIP Complex in Recruitment of Tel1ATM to Telomeres in Fission Yeast

Subramanian, L., & Nakamura, T. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000839 · Cited by 16

CGK733 enhances multinucleated cell formation and cytotoxicity induced by taxol in Chk1-deficient HBV-positive hepatocellular carcinoma cells

Wang, H., Zuo, B., Wang, H., Ren, L., Yang, P. H., Zeng, M., Duan, D., Liu, C., & Li, M. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.04.115 · Cited by 16

Influence of Human p53 on Plant Development

Ma, H., Song, T., Wang, T., & Wang, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162840 · Cited by 16

Pot1a Prevents Telomere Dysfunction and ATM-Dependent Neuronal Loss

Lee, Y., Brown, E. J., Chang, S. S., & McKinnon, P. J. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4245-13.2014 · Cited by 16

Tumor Cell Death Mediated by Peptides That Recognize Branched Intermediates of DNA Replication and Repair

Dey, M., Patra, S., Su, L. Y., & Segall, A. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078751 · Cited by 16

Genetic Interactions of the Aspergillus nidulans atmAATM Homolog With Different Components of the DNA Damage Response Pathway

Malavazi, I., Lima, J. F., de Castro, P. A., Savoldi, M., Goldman, M. H. S., & Goldman, G. H. (2008) · Genetics · doi:10.1534/genetics.107.080879 · Cited by 15

Exploiting DNA Replication Stress as a Therapeutic Strategy for Breast Cancer

Zhang, J., Chan, D. W., & Lin, S. (2022) · Biomedicines · doi:10.3390/biomedicines10112775 · Cited by 14

Mechanism of T‐oligo‐induced cell cycle arrest in Mia‐Paca pancreatic cancer cells

Rankin, A. M., Sarkar, S., & Faller, D. V. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22997 · Cited by 15

Working hard for recovery: mitotic kinases in the DNA damage checkpoint

Peng, A. (2013) · Cell & Bioscience · doi:10.1186/2045-3701-3-20 · Cited by 13

Anti-tumoral effect of arsenic compound, sodium metaarsenite (KML001), in non-Hodgkin’s lymphoma: an in vitro and in vivo study

Yoon, J. S., Hwang, D. W., Kim, E. S., Kim, J. S., Kim, S., Chung, H. J., Lee, S. K., Yi, J. H., Uhm, J., Won, Y., et al. (2015) · Investigational New Drugs · doi:10.1007/s10637-015-0301-z · Cited by 15

DNA damage response is hijacked by human papillomaviruses to complete their life cycle

Hong, S.-Y. (2017) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b1600306 · Cited by 17

The POU-Domain Transcription Factor Oct-6/POU3F1 as a Regulator of Cellular Response to Genotoxic Stress

Fionda, C., Bona, D. D., Kosta, A., Stabile, H., Santoni, A., & Cippitelli, M. (2019) · Cancers · doi:10.3390/cancers11060810 · Cited by 16

SCFSKP2 regulates APC/CCDH1-mediated degradation of CTIP to adjust DNA-end resection in G2-phase

Li, F., Mladenov, E., Mortoga, S., & Iliakis, G. E. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-02755-9 · Cited by 16

FBXO31: A New Player in the Ever-Expanding DNA Damage Response Orchestra

Shiloh, Y. (2009) · Science Signaling · doi:10.1126/scisignal.296pe73 · Cited by 15

CBP-93872 Inhibits NBS1-Mediated ATR Activation, Abrogating Maintenance of the DNA Double-Strand Break–Specific G2 Checkpoint

Hirokawa, T., Shiotani, B., Shimada, M., Murata, K., Johmura, Y., Haruta, M., Tahara, H., Takeyama, H., & Nakanishi, M. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-3604 · Cited by 15

Chromatin modification and NBS1: their relationship in DNA double-strand break repair

Saito, Y., Zhou, H., & Kobayashi, J. (2015) · Genes & Genetic Systems · doi:10.1266/ggs.15-00010 · Cited by 15

PCNA-Ub polyubiquitination inhibits cell proliferation and induces cell-cycle checkpoints

Qin, Z., Bai, Z., Sun, Y. J., Niu, X., & Xiao, W. (2016) · Cell Cycle · doi:10.1080/15384101.2016.1245247 · Cited by 16

ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in Trypanosoma brucei

Marín, P. M., Obonaga, R., Pavani, R., da Silva, M. S., de Araujo, C. B., Lima, A. A., Avila, C. C., Cestari, I. D. S., Machado, C. R., & Elias, M. C. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.602956 · Cited by 15

Response to Ovarian Stimulation for Urgent Fertility Preservation before Gonadotoxic Treatment in BRCA-Pathogenic-Variant-Positive Breast Cancer Patients

Moujahed, L. E., Philis, R., Grynberg, M., Laot, L., Mur, P., Amsellem, N., Mayeur, A., Benoit, A., Rakrouki, S., Sifer, C., et al. (2023) · Cancers · doi:10.3390/cancers15030895 · Cited by 14

Telomere capping and cellular checkpoints: clues from fruit flies

Ciapponi, L., & Cenci, G. (2008) · Cytogenetic and Genome Research · doi:10.1159/000167824 · Cited by 14

The fellowship of the RING: BRCA1, its partner BARD1 and their liaison in DNA repair and cancer

Russi, M., Marson, D., Fermeglia, A., Aulić, S., Fermeglia, M., Laurini, E., & Pricl, S. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.108009 · Cited by 14

Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis

Longhese, M. P., Guerini, I., Baldo, V., & Clerici, M. (2007) · DNA repair · doi:10.1016/j.dnarep.2007.09.006 · Cited by 15

NBS 1 directly activates ATR independently of MRE 11 and TOPBP 1

Kobayashi, M., Hayashi, N., Takata, M., & Yamamoto, K. (2013) · Genes to Cells · doi:10.1111/gtc.12031 · Cited by 14

Radiosensibilité, radiocurabilité et réparation

Vogin, G. (2011) · Cancer/Radiothérapie · doi:10.1016/j.canrad.2010.10.004 · Cited by 14

Identification of potential radiation-responsive biomarkers based on human orthologous genes with possible roles in DNA repair pathways by comparison between Arabidopsis thaliana and homo sapiens

Zhao, L., He, X., Shang, Y., Bao, C., Peng, A., Lei, X., Han, P. D., Mi, D., & Sun, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.135076 · Cited by 14

Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis

Gobbini, E., Trovesi, C., Cassani, C., & Longhese, M. P. (2014) · Molecular & Cellular Oncology · doi:10.4161/mco.29901 · Cited by 15

The role of the Fanconi anemia network in the response to DNA replication stress

Gari, K., & Constantinou, A. (2009) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230903154150 · Cited by 14

Haploinsufficiency of DNA Damage Response Genes and their Potential Influence in Human Genomic Disorders

O’Driscoll, M. (2008) · Current Genomics · doi:10.2174/138920208784340795 · Cited by 15

The mechanism and clinical application of DNA damage repair inhibitors combined with immune checkpoint inhibitors in the treatment of urologic cancer

Xie, D., Jiang, B., Wang, S., Wang, Q., & Wu, G. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1200466 · Cited by 15

Lyn tyrosine kinase promotes silencing of ATM-dependent checkpoint signaling during recovery from DNA double-strand breaks

Fukumoto, Y., Kuki, K., Morii, M., Miura, T., Honda, T., Ishibashi, K., Hasegawa, H., Kubota, S., Ide, Y., Yamaguchi, N., et al. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.08.113 · Cited by 13

Role of NBS1 in DNA damage response and its relationship with cancer development

Saito, Y., Fujimoto, H., & Kobayashi, J. (2013) · Institutional Repositories DataBase (IRDB) · doi:10.21037/1097 · Cited by 13

Protective Mechanisms Against DNA Replication Stress in the Nervous System

Charlier, C. F., & Martins, R. A. P. (2020) · Genes · doi:10.3390/genes11070730 · Cited by 16

ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions

Soni, A., Duan, X., Stuschke, M., & Iliakis, G. E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147506 · Cited by 13

Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation

Zhou, S., Xi, Y., Chen, Y., Fu, F., Yan, W., Li, M., Wu, Y., Luo, A., Li, Y., & Wang, S. (2022) · Cells · doi:10.3390/cells11233920 · Cited by 13

The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway

Song, J., Ma, J., Liu, X., Huang, Z., Li, L., Li, L., Luo, L., Ni, R., & He, J. (2023) · npj Regenerative Medicine · doi:10.1038/s41536-023-00294-3 · Cited by 13

Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ)

Hu, X., Li, Z., Ding, Y., Geng, Q., Xiahou, Z., Ru, H., Dong, M., Xu, X., & Li, J. (2017) · Cell Cycle · doi:10.1080/15384101.2017.1418235 · Cited by 13

Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy

Chen, Y., Li, Z., Xu, Z., Tang, H., Guo, W., Sun, X., Zhang, W., Zhang, J., Wan, X., Jiang, Y., et al. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0453-9 · Cited by 13

The DNA damage inducible lncRNA SCAT7 regulates genomic integrity and topoisomerase 1 turnover in lung adenocarcinoma

Statello, L., Ali, M. M., Reischl, S., Mahale, S. P., Kosalai, S. T., Huarte, M., & Kanduri, C. (2021) · NAR Cancer · doi:10.1093/narcan/zcab002 · Cited by 13

Molecular Carcinogenesis

Zachariadis, M., Evangelou, K., Kastrinakis, N. G., Papanagnou, P., & Gorgoulis, V. G. (2010) · Springer eBooks · doi:10.1007/978-3-540-71915-1_74 · Cited by 13

Changing of the Guard: How ATM Hands Off DNA Double-Strand Break Signaling to ATR

Rhind, N. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.03.004 · Cited by 13

Cellular responses to DNA damage: Current state of the field and review of the 52nd Benzon Symposium

Lukas, J., Bohr, V. A., & Halazonetis, T. D. (2006) · DNA repair · doi:10.1016/j.dnarep.2006.01.006 · Cited by 13

Loss of anchorage in checkpoint-deficient cells increases genomic instability and promotes oncogenic transformation

Cremona, C. A., & Lloyd, A. C. (2009) · Journal of Cell Science · doi:10.1242/jcs.047126 · Cited by 14

ATM localization and gene expression in the adult mouse eye.

Leemput, J., Masson, C., Bigot, K., Errachid, A., Dansault, A., Provost, A. C., Gadin, S., Aoufouchi, S., Ménasche, M., & Abitbol, M. M. (2009) · PubMed Central · Cited by 12

Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling

Dibitetto, D., Sims, J. R., Ascenção, C. F. R., Feng, K., Kim, D.-S., Oberly, S., Freire, R., & Smolka, M. B. (2020) · NAR Cancer · doi:10.1093/narcan/zcaa006 · Cited by 13

Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition

Whiteaker, J. R., Wang, T., Zhao, L., Schoenherr, R. M., Kennedy, J. J., Voytovich, U. J., Ivey, R. G., Huang, D., Lin, C., Colantonio, S., et al. (2021) · Cancers · doi:10.3390/cancers13153843 · Cited by 12

A Novel Role for RNF126 in the Promotion of G2 Arrest via Interaction With 14-3-3σ

Fa, P., Qiu, Z., Wang, Q., Yan, C., & Zhang, J. (2021) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2021.09.025 · Cited by 12

Cdk phosphorylation of Chk1 regulates efficient Chk1 activation and multiple checkpoint proficiency

Xu, N., Libertini, S., Zhang, Y., & Gillespie, D. A. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.08.119 · Cited by 12

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

Evison, B. J., Pastuovic, M., Bilardi, R. A., Forrest, R. A., Pumuye, P. P., Sleebs, B. E., Watson, K. G., Phillips, D. R., & Cutts, S. M. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.08.013 · Cited by 12

RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling

Kar, A., Kaur, M., Ghosh, T., Khan, M. M., Sharma, A., Shekhar, R., Varshney, A., & Saxena, S. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv369 · Cited by 12

Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair

Udayakumar, D., PANDITA, R. K., Horikoshi, N., Liu, Y., Liu, Q., Wong, K., Hunt, C. R., Gray, N. S., Minna, J. D., Pandita, T. K., et al. (2016) · Radiation Research · doi:10.1667/rr14373.1 · Cited by 12

The effect of DHEA on apoptosis and cohesin levels in oocytes in aged mice

Chu, N., Gui, Y., Qiu, X., Zhang, N., Li, L., Li, D., Tang, W., Gober, H.-J., Zhang, B., & Wang, L. (2017) · BioScience Trends · doi:10.5582/bst.2017.01108 · Cited by 12

RMI1 contributes to DNA repair and to the tolerance to camptothecin

Fang, L., Sun, X., Wang, Y., Du, L., Ji, K., Wang, J., He, N., Liu, Y., Wang, Q., Zhai, H., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201802014r · Cited by 12

Overview of genetic signaling pathway interactions within cutaneous malignancies

Maner, B. S., Dupuis, L., Su, A., Jueng, J., Harding, T. P., Meisenheimer, J. L., Siddiqui, F. S., Hardack, M. R., Aneja, S., & Solomon, J. A. (2020) · Journal of Cancer Metastasis and Treatment · doi:10.20517/2394-4722.2020.60 · Cited by 12

The Role of MRN in the S-Phase DNA Damage Checkpoint Is Independent of Its Ctp1-dependent Roles in Double-Strand Break Repair and Checkpoint Signaling

Porter-Goff, M. E., & Rhind, N. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-09-0986 · Cited by 12

ATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stability

Shin, M. H., Yuan, M., Zhang, H., Margolick, J. B., & Kai, M. (2012) · Cell Cycle · doi:10.4161/cc.20161 · Cited by 11

In vivo role of checkpoint kinase 2 in signaling telomere dysfunction

Beccaria, M. G., Martínez, P., Flores, J. M., & Blasco, M. A. (2014) · Aging Cell · doi:10.1111/acel.12237 · Cited by 11

HUS1 regulates in vivo responses to genotoxic chemotherapies

Balmus, G., Lim, P. X., Oswald, A. B., Hume, K. R., Cassano, A., Pierre, J., Hill, A., Huang, W., August, A., Stokol, T., et al. (2015) · Oncogene · doi:10.1038/onc.2015.118 · Cited by 11

UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway

Warmerdam, D. O., Brinkman, E. K., Marteijn, J. A. F., Medema, R. H., Kanaar, R., & Smits, V. A. J. (2013) · Journal of Cell Science · doi:10.1242/jcs.118265 · Cited by 11

Decreased translation of p21waf1mRNA causes attenuated p53 signaling in some p53 wild-type tumors

Chang, L.-J., & Eastman, A. R. (2012) · Cell Cycle · doi:10.4161/cc.20208 · Cited by 11

Sharpening the ends for repair: mechanisms and regulation of DNA resection

Paudyal, S. C., & You, Z. (2016) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmw043 · Cited by 14

Uncoupling Sae2 Functions in Downregulation of Tel1 and Rad53 Signaling Activities

Colombo, C. V., Menin, L., Ranieri, R., Bonetti, D., Clerici, M., & Longhese, M. P. (2018) · Genetics · doi:10.1534/genetics.118.301830 · Cited by 12

Inhibition of DNA repair protein RAD51 affects porcine preimplantation embryo development

Jin, Z., Shen, X., Shuang, L., Kwon, J., Seong, M.-J., & Kim, N. (2019) · Reproduction · doi:10.1530/rep-18-0271 · Cited by 11

Regulatory Approach for Transitioning from Gamma Ray to X-ray Radiation Sterilization

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Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906

Soares, D. G., Battistella, A., Rocca, C. J., Matuo, R., Henriques, J. A. P., Larsen, A. K., & Escargueil, A. E. (2011) · Biochemical Journal · doi:10.1042/bj20101770 · Cited by 11

Cyclooxygenase-2 Up-Regulates Ataxia Telangiectasia and Rad3 Related through Extracellular Signal-Regulated Kinase Activation

Kim, Y., Lee, E. J., Park, S., Cho, K. H., Kim, J. Y., & Pyo, H. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0493 · Cited by 11

Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses

Choi, S. H., & Yoo, H. Y. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.08.158 · Cited by 11

Balancing Life-or-Death Decisions

Bártek, J., & Lukas, J. (2006) · Science · doi:10.1126/science.1133758 · Cited by 11

Systematic transcriptomic analysis and temporal modelling of human fibroblast senescence

Scanlan, R.-L., Pease, L., O’Keefe, H., Guimera, A. M., Rasmussen, L. J., Wordsworth, J., & Shanley, D. P. (2024) · Frontiers in Aging · doi:10.3389/fragi.2024.1448543 · Cited by 11

Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility

Fahmideh, M. A., Lavebratt, C., Schüz, J., Röösli, M., Tynes, T., Grotzer, M. A., Johansen, C., Kuehni, C. E., Lannering, B., Prochazka, M., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.11575 · Cited by 10

ATM and ATR checkpoint kinase pathways: A concise review

Chauhan, N., Wagh, V., Joshi, P., & Jariyal, H. (2020) · Advances in Human Biology · doi:10.4103/aihb.aihb_78_19 · Cited by 9

Inactivation of Mad2B Enhances Apoptosis in Human Cervical Cancer Cell Line upon Cisplatin-Induced DNA Damage

Kim, J. H., Kim, H. R., & Patel, R. (2023) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2022.130 · Cited by 10

Glycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1)

Shin, S., Wolgamott, L., & Yoon, S.-O. (2012) · Cell Cycle · doi:10.4161/cc.11.6.19784 · Cited by 10

Targeted Mutations in the ATR Pathway Define Agent-Specific Requirements for Cancer Cell Growth and Survival

Wilsker, D. F., Chung, J., Pradilla, I. F., Petermann, E., Helleday, T., & Bunz, F. (2011) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-11-0675 · Cited by 10

The Role of RNA in DNA Breaks, Repair and Chromosomal Rearrangements

Murashko, M. M., Stasevich, E. M., Schwartz, A. M., Kuprash, D. V., Uvarova, A. N., & Демин, Д. Э. (2021) · Biomolecules · doi:10.3390/biom11040550 · Cited by 10

PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development

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Dynamic changes to survivin subcellular localization are initiated by DNA damage

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The N-terminus of RPA large subunit and its spatial position are important for the 5′->3′ resection of DNA double-strand breaks

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The Journal of Experimental Medicine CORRESPONDENCE Oscar Fernandez-Capetillo:

Cuadrado, M., Martínez-Pastor, B., Murga, M., & Toledo, L. I. (2013)

P (2011) Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks. Mol Cell Biol 31: 573–583

Limbo, O., Porter-Goff, M. E., Rhind, N., & Russell, P. R. (2016)