Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

Nanotubular Highways for Intercellular Organelle Transport

Rustom, A., Saffrich, R., Markovic, I., Walther, P., & Gerdes, H.-H. (2004) · Science · doi:10.1126/science.1093133 · Cited by 2,038

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Mattapallil, J. J., Douek, D. C., Hill, B. J., Nishimura, Y., Martin, M. A., & Roederer, M. (2005) · Nature · doi:10.1038/nature03501 · Cited by 1,269

Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells

Li, Q., Duan, L., Estes, J. D., Ma, Z.-M., Rourke, T., Wang, Y., Reilly, C., Carlis, J. V., Miller, C. J., & Haase, A. T. (2005) · Nature · doi:10.1038/nature03513 · Cited by 942

The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges

Stinchcombe, J. C., Bossi, G., Booth, S., & Griffiths, G. M. (2001) · Immunity · doi:10.1016/s1074-7613(01)00234-5 · Cited by 817

Imaging of Germinal Center Selection Events During Affinity Maturation

Allen, C. D. C., Okada, T., Tang, H. L., & Cyster, J. G. (2006) · Science · doi:10.1126/science.1136736 · Cited by 784

HIV-1 Gag proteins: diverse functions in the virus life cycle

Freed, E. O. (1998) · Virology · doi:10.1006/viro.1998.9398 · Cited by 717

Recruitment of HIV and Its Receptors to Dendritic Cell-T Cell Junctions

McDonald, D., Wu, L., Bohks, S. M., KewalRamani, V. N., Unutmaz, D., & Hope, T. J. (2003) · Science · doi:10.1126/science.1084238 · Cited by 707

HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse

Jolly, C., Kashefi, K., Hollinshead, M., & Sattentau, Q. J. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20030648 · Cited by 623

Imaging the Single Cell Dynamics of CD4+ T Cell Activation by Dendritic Cells in Lymph Nodes

Miller, M. J., Safrina, O., Parker, I., & Cahalan, M. D. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20041236 · Cited by 545

GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission

Roux, A., Uyhazi, K., Frost, A., & Camilli, P. D. (2006) · Nature · doi:10.1038/nature04718 · Cited by 524

Brain tumour cells interconnect to a functional and resistant network

Osswald, M., Jung, E., Sahm, F., Solecki, G. M., Venkataramani, V., Blaes, J., Heuer, S., Horstmann, H., Wiestler, B., Syed, M., et al. (2015) · Nature · doi:10.1038/nature16071 · Cited by 1,180

Mechanisms of mesenchymal stem/stromal cell function

Spees, J. L., Lee, R. H., & Gregory, C. A. (2016) · Stem Cell Research & Therapy · doi:10.1186/s13287-016-0363-7 · Cited by 912

HIV-1 assembly, budding, and maturation

Sundquist, W. I., & Krausslich, H.-G. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006924 · Cited by 814

Prions hijack tunnelling nanotubes for intercellular spread

Gousset, K., Schiff, E., Langevin, C., Marijanovic, Z., Caputo, A., Browman, D., Chenouard, N., de Chaumont, F., Martino, A., Enninga, J., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1841 · Cited by 639

Avoiding the void: Cell-to-cell spread of human viruses

Sattentau, Q. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1972 · Cited by 614

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

Okoye, I., Coomes, S. M., Pelly, V. S., Czieso, S., Papayannopoulos, V., Tolmachova, T., Seabra, M. C., & Wilson, M. S. (2014) · Immunity · doi:10.1016/j.immuni.2014.05.019 · Cited by 619

Setting the stage: host invasion by HIV

Hladik, F., & McElrath, M. J. (2008) · Nature reviews. Immunology · doi:10.1038/nri2302 · Cited by 611

Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells

Wang, X., & Gerdes, H.-H. (2015) · Cell Death and Differentiation · doi:10.1038/cdd.2014.211 · Cited by 529

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

Pasquier, J., Guerrouahen, B. S., Al-Thawadi, H., Ghiabi, P., Maleki, M., Abu-Kaoud, N., Jacob, A., Mirshahi, M., Galas, L., Rafii, S., et al. (2013) · Journal of Translational Medicine · doi:10.1186/1479-5876-11-94 · Cited by 514

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF-β1 Signaling Pathway

Ye, X.-Z., Xu, S., Xin, Y.-H., Yu, S., Ping, Y., Chen, L., Xiao, H., Wang, B., Liang, Y., Wang, Q., et al. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103248 · Cited by 477

Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma

Lou, E., Fujisawa, S., Morozov, A., Barlas, A., Romin, Y., Dogan, Y., Gholami, S., Moreira, A. L., Manova-Todorova, K., & Moore, M. A. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033093 · Cited by 420

Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes

Abounit, S., Bousset, L., Loria, F., Zhu, S., de Chaumont, F., Pieri, L., Olivo‐Marin, J., Melki, R., & Zurzolo, C. (2016) · The EMBO Journal · doi:10.15252/embj.201593411 · Cited by 414

Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells

Saha, T., Dash, C. P., Jayabalan, R., Khiste, S., Kulkarni, A., Kurmi, K., Mondal, J., Majumder, P. K., Bardia, A., Jang, H. L., et al. (2021) · Nature Nanotechnology · doi:10.1038/s41565-021-01000-4 · Cited by 427

Tunneling-nanotube development in astrocytes depends on p53 activation

Wang, Y., Cui, J., Sun, X., & Zhang, Y. (2010) · Cell Death and Differentiation · doi:10.1038/cdd.2010.147 · Cited by 422

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

Hase, K., Kimura, S., Takatsu, H., Ohmae, M., Kawano, S., Kitamura, H., Ito, M., Watarai, H., Hazelett, C. C., Yeaman, C., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1990 · Cited by 402

Wiring through tunneling nanotubes--from electrical signals to organelle transfer

Abounit, S., & Zurzolo, C. (2012) · Journal of Cell Science · doi:10.1242/jcs.083279 · Cited by 386

The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system

van Riel, D., Verdijk, R., & Kuiken, T. (2015) · The Journal of Pathology · doi:10.1002/path.4461 · Cited by 394

Itinerant exosomes: emerging roles in cell and tissue polarity

Lakkaraju, A., & Rodriguez-Boulan, E. J. (2008) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.03.002 · Cited by 408

Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts

Torralba, D., Baixauli, F., Villarroya‐Beltri, C., Fernández‐Delgado, I., Latorre, A., Acín‐Pérez, R., Martin-Cofreces, N. B., Jaso-Tamame, A. L., Iborra, S., Jorge, I., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05077-9 · Cited by 386

Membrane nanotubes: dynamic long-distance connections between animal cells

Davis, D. M., & Sowinski, S. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2399 · Cited by 377

Virus cell-to-cell transmission

Mothes, W., Sherer, N. M., Jin, J., & Zhong, P. (2010) · Journal of Virology · doi:10.1128/jvi.00443-10 · Cited by 353

Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels

Wang, X., Veruki, M. L., Bukoreshtliev, N. V., Hartveit, E., & Gerdes, H. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006785107 · Cited by 331

Transfer of extracellular vesicles during immune cell‐cell interactions

Gutiérrez‐Vázquez, C., Villarroya‐Beltri, C., Mittelbrunn, M., & Sánchez‐Madrid, F. (2012) · Immunological Reviews · doi:10.1111/imr.12013 · Cited by 324

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

Tardivel, M., Bégard, S., Bousset, L., Dujardin, S., Coens, A., Melki, R., Buée, L., & Colin, M. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-016-0386-4 · Cited by 305

HIV-infected T cells are migratory vehicles for viral dissemination

Murooka, T. T., Deruaz, M., Marangoni, F., Vrbanac, V. D., Seung, E., von Andrian, U. H., Tager, A. M., Luster, A. D., & Mempel, T. R. (2012) · Nature · doi:10.1038/nature11398 · Cited by 322

Intercellular transfer mediated by tunneling nanotubes

Gerdes, H., & Carvalho, R. (2008) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2008.03.005 · Cited by 324

Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor-Like State Through Partial Cell Fusion and Mitochondria Transfer

Acquistapace, A., Bru, T., Lesault, P., Figeac, F., Coudert, A. E., Coz, O. L., Christov, C., Baudin, X., Auber, F., Yiou, R., et al. (2011) · Stem Cells · doi:10.1002/stem.632 · Cited by 312

Design and properties of functional nanotubes from the self-assembly of cyclic peptide templates

Chapman, R., Danial, M., Koh, M. L., Jolliffe, K. A., & Perrier, S. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35172b · Cited by 310

Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

Eugenin, E. A., Gaskill, P. J., & Berman, J. W. (2009) · Cellular Immunology · doi:10.1016/j.cellimm.2008.08.005 · Cited by 304

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

Xu, W., Santini, P. A., Sullivan, J. S., He, B., Shan, M., Ball, S. C., Dyer, W. B., Ketas, T. J., Chadburn, A., Cohen-Gould, L., et al. (2009) · Nature Immunology · doi:10.1038/ni.1753 · Cited by 302

Understanding wiring and volume transmission

Agnati, L. F., Guidolin, D., Guescini, M., Genedani, S., & Fuxé, K. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.03.003 · Cited by 296

The discovery of central monoamine neurons gave volume transmission to the wired brain

Fuxé, K., Dahlström, A. B., JONSSON, G., Marcellino, D. J., Guescini, M., Dam, M., Manger, P. R., & Agnati, L. F. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.10.012 · Cited by 285

Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II+ Cells in the Mouse Cornea

Chinnery, H. R., Pearlman, E. M., & McMenamin, P. G. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.9.5779 · Cited by 278

Trophic Effects of Mesenchymal Stem Cells in Tissue Regeneration

Fu, Y., Karbaat, L., Wu, L., Leijten, J., Both, S. K., & Karperien, M. (2017) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2016.0365 · Cited by 277

Paracrine induction of endothelium by tumor exosomes

Hood, J. L., Pan, H., Lanza, G. M., & Wickline, S. A. (2009) · Laboratory Investigation · doi:10.1038/labinvest.2009.94 · Cited by 273

Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells

Sartori-Rupp, A., Cervantes, D. C., Pepe, A., Gousset, K., Delage, E., Corroyer-Dulmont, S., Schmitt, C., Locker, J. K., & Zurzolo, C. (2019) · Nature Communications · doi:10.1038/s41467-018-08178-7 · Cited by 274

Viral effects on the content and function of extracellular vesicles

Raab‐Traub, N., & Dittmer, D. P. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.60 · Cited by 270

Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion

Mineo, M., Garfield, S. H., Taverna, S., Flugy, A. M., Leo, G. D., Alessandro, R., & Kohn, E. C. (2011) · Angiogenesis · doi:10.1007/s10456-011-9241-1 · Cited by 276

Tunneling Nanotubes and Gap Junctions–Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions

Ariazi, J. L., Benowitz, A. B., de Biasi, V., den Boer, M. L., Cherqui, S., Cui, H., Douillet, N., Eugenín, E. A., Favre, D., Goodman, S. M., et al. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00333 · Cited by 250

HIV interactions with monocytes and dendritic cells: viral latency and reservoirs

Coleman, C. M., & Wu, L. J. (2009) · Retrovirology · doi:10.1186/1742-4690-6-51 · Cited by 257

Cytonemes and tunneling nanotubules in cell–cell communication and viral pathogenesis

Sherer, N. M., & Mothes, W. (2008) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.07.003 · Cited by 246

Exosomes as a Nanodelivery System: a Key to the Future of Neuromedicine?

Aryani, A., & Denecke, B. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-9054-5 · Cited by 242

The Extracellular Matrix in Skin Inflammation and Infection

Pfisterer, K., Shaw, L. E., Symmank, D., & Weninger, W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.682414 · Cited by 258

Tunneling nanotubes

Austefjord, M. W., Gerdes, H., & Wang, X. (2014) · Communicative & Integrative Biology · doi:10.4161/cib.27934 · Cited by 240

Cell-to-cell transmission of viruses

Zhong, P., Agosto, L. M., Munro, J. B., & Mothes, W. (2013) · Current Opinion in Virology · doi:10.1016/j.coviro.2012.11.004 · Cited by 231

Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells

Bukoreshtliev, N. V., Wang, X., Hodneland, E., Gurke, S., Barroso, J., & Gerdes, H. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.03.065 · Cited by 226

Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies

Abela, I. A., Berlinger, L., Schanz, M., Reynell, L., Günthard, H. F., Rusert, P., & Trkola, A. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002634 · Cited by 241

Simultaneous Cell-to-Cell Transmission of Human Immunodeficiency Virus to Multiple Targets through Polysynapses

Rudnicka, D., Feldmann, J., Porrot, F., Wietgrefe, S., Guadagnini, S., Prévost, M.-C., Estaquier, J., Haase, A. T., Sol-Foulon, N., & Schwartz, O. (2009) · Journal of Virology · doi:10.1128/jvi.00282-09 · Cited by 229

Single-Virus Tracking: From Imaging Methodologies to Virological Applications

Liu, S., Wang, Z., Xie, H., Liu, A., Lamb, D. C., & Pang, D. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00692 · Cited by 230

Tunneling nanotubes, an emerging intercellular communication route in development

Gerdes, H., Rustom, A., & Wang, X. (2012) · Mechanisms of Development · doi:10.1016/j.mod.2012.11.006 · Cited by 215

Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells

Chauveau, A., Aucher, A., Eissmann, P., Vivier, É., & Davis, D. M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910074107 · Cited by 210

Role of connexin 43 in different forms of intercellular communication – gap junctions, extracellular vesicles and tunnelling nanotubes

Ribeiro‐Rodrigues, T., Martins‐Marques, T., Morel, S., Kwak, B. R., & Girão, H. (2017) · Journal of Cell Science · doi:10.1242/jcs.200667 · Cited by 209

The art of cellular communication: tunneling nanotubes bridge the divide

Gurke, S., Barroso, J. F., & Gerdes, H. (2008) · Histochemistry and Cell Biology · doi:10.1007/s00418-008-0412-0 · Cited by 210

Virological Synapse-Mediated Spread of Human Immunodeficiency Virus Type 1 between T Cells Is Sensitive to Entry Inhibition

Martin, N., Welsch, S., Jolly, C., Briggs, J. A. G., Vaux, D., & Sattentau, Q. J. (2010) · Journal of Virology · doi:10.1128/jvi.02651-09 · Cited by 199

A Family of Plasmodesmal Proteins with Receptor-Like Properties for Plant Viral Movement Proteins

Amari, K., Boutant, E., Hofmann, C., Schmitt‐Keichinger, C., Fernández‐Calvino, L., Didier, P., Lerich, A., Mutterer, J., Thomas, C. L., Heinlein, M., et al. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001119 · Cited by 213

Myo10 is a key regulator of TNT formation in neuronal cells

Gousset, K., Marzo, L., Commère, P., & Zurzolo, C. (2013) · Journal of Cell Science · doi:10.1242/jcs.129239 · Cited by 208

Mechanisms for Cell-to-Cell Transmission of HIV-1

Bracq, L., Xie, M., Bénichou, S., & Bouchet, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00260 · Cited by 215

Host factors involved in retroviral budding and release

Martin‐Serrano, J., & Neil, S. J. D. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2596 · Cited by 219

HIV Traffics through a Specialized, Surface-Accessible Intracellular Compartment during trans-Infection of T Cells by Mature Dendritic Cells

Yu, H. J., Reuter, M. A., & McDonald, D. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.1000134 · Cited by 193

Automatic transportation of biological cells with a robot-tweezer manipulation system

Hu, S., & Sun, D. B. (2011) · The International Journal of Robotics Research · doi:10.1177/0278364911413479 · Cited by 188

Tunneling Nanotubes: Intimate Communication between Myeloid Cells

Dupont, M., Souriant, S., Lugo‐Villarino, G., Maridonneau‐Parini, I., & Vérollet, C. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00043 · Cited by 194

Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy

Vignais, M., Caicedo, A., Brondello, J., & Jørgensen, C. (2017) · Stem Cells International · doi:10.1155/2017/6917941 · Cited by 196

Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes

He, K., Shi, X., Zhang, X., Dang, S., Ma, X., Liu, F., Xu, M., Lv, Z., Han, D. C., Fang, X., et al. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr189 · Cited by 189

Cell-Cell Spread of Human Immunodeficiency Virus Type 1 Overcomes Tetherin/BST-2-Mediated Restriction in T cells

Jolly, C. L., Booth, N. J., & Neil, S. J. D. (2010) · Journal of Virology · doi:10.1128/jvi.01447-10 · Cited by 185

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

Polak, R., de Rooij, B., Pieters, R., & den Boer, M. L. (2015) · Blood · doi:10.1182/blood-2015-03-634238 · Cited by 188

Peering into tunneling nanotubes—The path forward

Cervantes, D. C., & Zurzolo, C. (2021) · The EMBO Journal · doi:10.15252/embj.2020105789 · Cited by 175

Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission

Van Prooyen, N., Gold, H., Andresen, V., Schwartz, O., Jones, K., Ruscetti, F., Lockett, S., Gudla, P., Venzon, D., & Franchini, G. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009635107 · Cited by 178

Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts

Crespo, Â. C., Mulik, S., Dotiwala, F., Ansara, J., Santara, S. S., Omdahl, K. I., Ovies, C., Junqueira, C., Tilburgs, T., Strominger, J. L., et al. (2020) · Cell · doi:10.1016/j.cell.2020.07.019 · Cited by 180

Production of Papillomavirus‐Based Gene Transfer Vectors

Buck, C. B., & Thompson, C. D. (2007) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb2601s37 · Cited by 173

Mitochondrial Transfer in Cancer: A Comprehensive Review

Zampieri, L. X., Silva‐Almeida, C., Rondeau, J. D., & Sonveaux, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22063245 · Cited by 179

Viral and host heterogeneity and their effects on the viral life cycle

Jones, J. E., Sage, V. L., & Lakdawala, S. S. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-00449-9 · Cited by 173

Multifaceted Roles of Tunneling Nanotubes in Intercellular Communication

Marzo, L., Gousset, K., & Zurzolo, C. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00072 · Cited by 177

The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis

Hanna, S. J., McCoy-Simandle, K., Miskolci, V., Guo, P., Cammer, M., Hodgson, L., & Cox, D. (2017) · Scientific Reports · doi:10.1038/s41598-017-08950-7 · Cited by 171

Cell Carriers for Oncolytic Viruses: Fed Ex for Cancer Therapy

Willmon, C. L., Harrington, K. J., Kottke, T. J., Prestwich, R. J. D., Melcher, A. A., & Vile, R. G. (2009) · Molecular Therapy · doi:10.1038/mt.2009.194 · Cited by 167

Influenza virus exploits tunneling nanotubes for cell-to-cell spread

Kumar, A., Kim, J. H., Ranjan, P., Metcalfe, M. G., Cao, W., Mishina, M., Gangappa, S., Guo, Z., Boyden, E. S., Zaki, S. R., et al. (2017) · Scientific Reports · doi:10.1038/srep40360 · Cited by 166

Sculpting and fusing biomimetic vesicle networks using optical tweezers

Bolognesi, G., Friddin, M. S., Salehi‐Reyhani, A., Barlow, N. E., Brooks, N. J., Ces, O., & Elani, Y. (2018) · Nature Communications · doi:10.1038/s41467-018-04282-w · Cited by 173

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

Muratori, C., Cavallin, L. E., Krätzel, K., Tinari, A., De Milito, A., Fais, S., D'Aloja, P., Federico, M., Vullo, V., Fomina, A., et al. (2009) · Cell Host & Microbe · doi:10.1016/j.chom.2009.06.009 · Cited by 164

Nanotubes, exosomes, and nucleic acid–binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease

Belting, M., & Wittrup, A. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200810038 · Cited by 163

Tunneling Nanotubes: The Fuel of Tumor Progression?

Pinto, G., Brou, C., & Zurzolo, C. (2020) · Trends in cancer · doi:10.1016/j.trecan.2020.04.012 · Cited by 158

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

Casartelli, N., Sourisseau, M., Feldmann, J., Guivel‐Benhassine, F., Mallet, A., Marcelin, A., Guatelli, J., & Schwartz, O. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000955 · Cited by 167

Microscale electroporation: challenges and perspectives for clinical applications

Lee, W. G., Demirci, U., & Khademhosseini, A. (2009) · Integrative Biology · doi:10.1039/b819201d · Cited by 154

Mechanisms of cellular communication through intercellular protein transfer

Ahmed, K. A., & Xiang, J. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01008.x · Cited by 153

The Ways of Actin: Why Tunneling Nanotubes Are Unique Cell Protrusions

Ljubojević, N., Henderson, J. M., & Zurzolo, C. (2020) · Trends in Cell Biology · doi:10.1016/j.tcb.2020.11.008 · Cited by 150

Pathways of cell-cell transmission of HTLV-1

Pique, C., & Jones, K. S. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00378 · Cited by 166

Tunneling nanotube (TNT)-like structures facilitate a constitutive, actomyosin-dependent exchange of endocytic organelles between normal rat kidney cells

Gurke, S., Barroso, J. F., Hodneland, E., Bukoreshtliev, N. V., Schlicker, O., & Gerdes, H. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.08.022 · Cited by 148

Senescent cells communicate via intercellular protein transfer

Biran, A., Perelmutter, M., Gal, H., Burton, D. G. A., Ovadya, Y., Vadai, E., Geiger, T., & Krizhanovsky, V. (2015) · Genes & Development · doi:10.1101/gad.259341.115 · Cited by 139

Tunneling nanotubes provide a route for SARS-CoV-2 spreading

Pepe, A., Pietropaoli, S., Vos, M. R. J., Spaeth, G. B., & Zurzolo, C. (2022) · Science Advances · doi:10.1126/sciadv.abo0171 · Cited by 144

HIV Proteins and Endothelial Dysfunction: Implications in Cardiovascular Disease

Anand, A. R., Rachel, G., & Parthasarathy, D. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2018.00185 · Cited by 142

Nanowired Bioelectric Interfaces

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