Transmission and spreading of tauopathy in transgenic mouse brain

Clavaguera, Florence, Bolmont, Tristan, Crowther, R. Anthony, Abramowski, Dorothee, Frank, Stephan, Probst, Alphonse, Fraser, Graham, Stalder, Anna K. +5 more·2009·Nature Cell Biology

Cited by (1,006)

Items 501–600 of 1,006

  1. Tau at the interface between neurodegeneration and neuroinflammation
    Didonna, Alessandro · 2020 · Genes & Immunity
  2. Beyond α-synuclein transfer: pathology propagation in Parkinson's disease
    Christian Hansen, Jiayi Li · 2012 · Trends in Molecular Medicine
  3. Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy
    Stacy A. Hussong, Andy Q. Banh, Candice E. Van Skike, Angela O. Dorigatti, Stephen F. Hernandez, Matthew J. Hart, Beatriz Ferrán, Haneen Makhlouf, Maria E. Gaczynska, Paweł A. Osmulski et al. · 2023 · Nature Communications
  4. Frontotemporal degeneration, the next therapeutic frontier: Molecules and animal models for frontotemporal degeneration drug development
    Adam L. Boxer, Michael Gold, Edward D. Huey, Fen‐Biao Gao, Edward A. Burton, Tiffany W. Chow, Aimee W. Kao, Blair R. Leavitt, Bruce T. Lamb, Megan E. Grether et al. · 2012 · Alzheimer s & Dementia
  5. Atypical parkinsonian syndromes: a general neurologist's perspective
    Angela Deutschländer, Owen A. Ross, Dennis W. Dickson, Zbigniew K. Wszołek · 2017 · European Journal of Neurology
  6. The Neurotoxic Role of Extracellular Tau Protein
    Álvaro Sebastián‐Serrano, Laura de Diego-García, Miguel Dı́az-Hernández · 2018 · International Journal of Molecular Sciences
  7. Alzheimer Disease
    Caselli, Richard J., Beach, Thomas G., Knopman, David S., Graff-Radford, Neill R. · 2017 · Mayo Clinic Proceedings
  8. Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice
    Héraud, Céline, Goufak, Doris, Ando, Kunie, Leroy, Karelle, Suain, Valérie, Yilmaz, Zehra, De Decker, Robert, Authelet, Michèle, Laporte, Vincent, Octave, Jean-Noël et al. · 2014 · Neurobiology of Disease
  9. Current Understanding of Neurodegenerative Diseases Associated With the Protein Tau
    Keith A. Josephs · 2017 · Mayo Clinic Proceedings
  10. Tau monomer encodes strains
    Apurwa M Sharma, Talitha L. Thomas, DaNae R. Woodard, Omar M. Kashmer, Marc I. Diamond · 2018 · eLife
  11. Tauopathies and Tau Oligomers
    Akihiko Takashima · 2013 · Journal of Alzheimer s Disease
  12. Spontaneous generation of anchorless prions in transgenic mice
    Jan Stöhr, Joel C. Watts, Giuseppe Legname, Abby Oehler, Azucena Lemus, Hoang-Oanh B. Nguyen, Joshua Sussman, Holger Wille, Stephen J. DeArmond, Stanley B. Prusiner et al. · 2011 · Proceedings of the National Academy of Sciences
  13. Murine models of Alzheimer's disease and their use in developing immunotherapies
    Thomas Wısnıewskı, Einar M. Sigurdsson · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  14. Accelerated Human Mutant Tau Aggregation by Knocking Out Murine Tau in a Transgenic Mouse Model
    Kunié Ando, Karelle Leroy, Céline Héraud, Zehra Yilmaz, Michèle Authelet, Valérie Suain, Robert De Decker, Jean‐Pierre Brion · 2011 · American Journal Of Pathology
  15. Interneurons, tau and amyloid-β in the piriform cortex in Alzheimer’s disease
    Saiz-Sanchez, Daniel, De la Rosa-Prieto, Carlos, Ubeda-Banon, Isabel, Martinez-Marcos, Alino · 2015 · Brain Structure and Function
  16. Cellular mechanisms of protein aggregate propagation
    Brandon B. Holmes, Marc I. Diamond · 2012 · Current Opinion in Neurology
  17. Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer's Disease
    Xilin Wu, Juan Piña-Crespo, Yun‐wu Zhang, Xiaochun Chen, Huaxi Xu · 2017 · Chinese Medical Journal
  18. Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading
    Franziska Kundel, Liu Hong, Benjamin Falcon, William A. McEwan, Thomas C. T. Michaels, Georg Meisl, Noemí Esteras, Andrey Y. Abramov, Tuomas P. J. Knowles, Michel Goedert et al. · 2018 · ACS Chemical Neuroscience
  19. Fate and propagation of endogenously formed Tau aggregates in neuronal cells
    Patricia Chastagner, Frida Loría, Jessica Vargas, Josh Tois, Marc I. Diamond, George N. Okafo, Christel Brou, Chiara Zurzolo · 2020 · EMBO Molecular Medicine
  20. Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer's disease variants
    Manja Lehmann, Cindee M. Madison, Pia Marie Ghosh, Zachary Miller, Michael D. Greicius, Joel H. Kramer, Giovanni Coppola, Bruce L. Miller, William J. Jagust, Maria Luisa Gorno‐Tempini et al. · 2015 · Neurobiology of Aging
  21. Animal models reveal role for tau phosphorylation in human disease
    Jürgen Götz, Amadeus Gladbach, Luis Pennanen, Janet van Eersel, Andreas Schild, Della C. David, Lars Matthias Ittner · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  22. Current directions in tau research: Highlights from Tau 2020
    Claire E. Sexton, Heather M. Snyder, Dirk Beher, Adam L. Boxer, Patrick Brannelly, Jean‐Pierre Brion, Luc Buée, Angela M. Cacace, Gaël Chételat, Martin Citron et al. · 2021 · Alzheimer s & Dementia
  23. Secretion of human tau fragments resembling CSF‐tau in Alzheimer's disease is modulated by the presence of the exon 2 insert
    WonHee Kim, Sangmook Lee, Garth F. Hall · 2010 · FEBS Letters
  24. Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes
    Christian Rungsted Andersson, Jeppe Falsig, Jeffrey B. Stavenhagen, Søren Christensen, Fredrik Kartberg, Nina Rosenqvist, Bente R. Finsen, Jan T. Pedersen · 2019 · Scientific Reports
  25. Military- and Sports-Related Mild Traumatic Brain Injury: Clinical Presentation, Management, and Long-Term Consequences
    Elaine R. Peskind, David L. Brody, Ibolja Černak, Ann Carolyn McKee, Robert Louis Ruff · 2013 · The Journal of Clinical Psychiatry
  26. From molecule to molecule and cell to cell: Prion-like mechanisms in amyotrophic lateral sclerosis
    Leslie I. Grad, Sarah M. Fernando, Neil R. Cashman · 2015 · Neurobiology of Disease
  27. Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates
    E-J Bae, N Y Yang, C Lee, S Kim, H-J Lee, SJ Lee · 2015 · Cell Death and Disease
  28. Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo
    Charisse N. Winston, Brent D. Aulston, Edward M. Rockenstein, Anthony Adame, Olga Prikhodko, Kishan N. Dave, Priyanka Mishra, Robert A. Rissman, Shauna H. Yuan · 2018 · Journal of Alzheimer s Disease
  29. Complement System in Alzheimer’s Disease
    Akash Shah, Uday Kishore, Abhishek Shastri · 2021 · International Journal of Molecular Sciences
  30. Analysis of in vivo turnover of tau in a mouse model of tauopathy
    Kaoru Yamada, Tirth K. Patel, Katja Hochgräfe, Thomas E. Mahan, Hong Jiang, Floy R. Stewart, Eva‐Maria Mandelkow, David M. Holtzman · 2015 · Molecular Neurodegeneration
  31. Involvement of Oligodendrocytes in Tau Seeding and Spreading in Tauopathies
    Isidró Ferrer, Meritxell Aguiló, Margarita Carmona, Pol Andrés‐Benito, Benjamı́n Torrejón-Escribano, Paula Garcia‐Esparcia, José Antonio del Rı́o · 2019 · Frontiers in Aging Neuroscience
  32. Misfolded Truncated Protein τ Induces Innate Immune Response via MAPK Pathway
    Kovac, Andrej, Zilka, Norbert, Kazmerova, Zuzana, Cente, Martin, Zilkova, Monika, Novak, Michal · 2011 · The Journal of Immunology
  33. Prions and protein-folding diseases: Review: Prions and protein-folding diseases
    Norrby, E. · 2011 · Journal of Internal Medicine
  34. SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation
    Rafaa Zeineddine, Jay Pundavela, Lisa Corcoran, Elise M. Stewart, Dzung Do‐Ha, Monique Bax, Gilles J. Guillemin, Kara L. Vine, Danny M. Hatters, Heath W. Ecroyd et al. · 2015 · Molecular Neurodegeneration
  35. Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau
    Siddiqua, Ayisha, Luo, Yin, Meyer, Virginia, Swanson, Michael A., Yu, Xiang, Wei, Guanghong, Zheng, Jie, Eaton, Gareth R., Ma, Buyong, Nussinov, Ruth et al. · 2012 · Journal of the American Chemical Society
  36. Aging‐related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes
    Isidró Ferrer, Meritxell Aguiló, Irene López González, Daniela Diaz Lucena, Aina Roig, Margarita Carmona, Franc Llorens, Paula Garcia‐Esparcia, Alejandra Martínez-Maldonado, Margalida A. Frau‐Méndez et al. · 2018 · Brain Pathology
  37. Potential mechanisms and implications for the formation of tau oligomeric strains
    Julia E. Gerson, Amritpal K. Mudher, Rakez Kayed · 2016 · Critical Reviews in Biochemistry and Molecular Biology
  38. Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
    Douglas M. Lopes, Sophie K. Llewellyn, Ian F. Harrison · 2022 · Translational Neurodegeneration
  39. Potential of the Antibody Against cis–Phosphorylated Tau in the Early Diagnosis, Treatment, and Prevention of Alzheimer Disease and Brain Injury
    Kun Ping Lu, Asami Kondo, Önder Albayram, Megan K. Herbert, Hekun Liu, Xiao Zhen Zhou · 2016 · JAMA Neurology
  40. Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease
    Morabito, Samuel, Miyoshi, Emily, Michael, Neethu, Swarup, Vivek · 2020 · Human Molecular Genetics
  41. Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
    Clément Danis, Elian Dupré, Orgeta Zejneli, Raphaëlle Caillierez, Alexis Arrial, Séverine Bégard, Justine Mortelecque, Sabiha Eddarkaoui, Anne Loyens, François‐Xavier Cantrelle et al. · 2022 · Molecular Therapy
  42. The necroptosis cell death pathway drives neurodegeneration in Alzheimer’s disease
    Sriram Balusu, Bart De Strooper · 2024 · Acta Neuropathologica
  43. Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?
    Ilaria Dal Prà, Anna Chiarini, Li Gui, Balu Chakravarthy, Raffaella Pacchiana, Emanuela Gardenal, James F. Whitfield, Ubaldo Armato · 2014 · The Neuroscientist
  44. Extracellular Tau Oligomers Induce Invasion of Endogenous Tau into the Somatodendritic Compartment and Axonal Transport Dysfunction
    Eric Swanson, Leigham Breckenridge, Lloyd P. McMahon, Sreemoyee Som, Ian McConnell, George S. Bloom · 2017 · Journal of Alzheimer s Disease
  45. The <scp>NLRP3</scp> inflammasome modulates tau pathology and neurodegeneration in a tauopathy model
    Stancu, Ilie Cosmin, Lodder, Chritica, Botella Lucena, Pablo, Vanherle, Sarah, Gutiérrez de Ravé, Manuel, Terwel, Dick, Bottelbergs, Astrid, Dewachter, Ilse · 2022 · Glia
  46. Tau and Amyloid Relationships with Resting-state Functional Connectivity in Atypical Alzheimer’s Disease
    Irene Sintini, Jonathan Graff‐Radford, David Thomas Jones, Hugo Botha, Peter R. Martin, Mary M. Machulda, Christopher G. Schwarz, Matthew L. Senjem, Jeffrey L. Gunter, Clifford R. Jack et al. · 2020 · Cerebral Cortex
  47. Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
    Airi Tarutani, Sofia Lövestam, Xianjun Zhang, Abhay Kotecha, Andrew Robinson, David M. A. Mann, Yuko Saito, Shigeo Murayama, Taisuke Tomita, Michel Goedert et al. · 2023 · FEBS Open Bio
  48. Corruption and Spread of Pathogenic Proteins in Neurodegenerative Diseases
    Lary C. Walker, Harry LeVine · 2012 · Journal of Biological Chemistry
  49. Regulatable transgenic mouse models of A lzheimer disease: onset, reversibility and spreading of T au pathology
    Katja Hochgräfe, Astrid Sydow, Eva‐Maria Mandelkow · 2013 · FEBS Journal
  50. Molecular Mechanisms in the Pathogenesis of Alzheimer’s disease and Tauopathies-Prion-Like Seeded Aggregation and Phosphorylation
    Masato Hasegawa · 2016 · Biomolecules
  51. Identification of disulfide cross-linked tau dimer responsible for tau propagation
    Do‐Hee Kim, Sungsu Lim, Md. Mamunul Haque, Nayeon Ryoo, Hyun‐Seok Hong, Hyewhon Rhim, Dong‐Eun Lee, Young‐Tae Chang, Jun‐Seok Lee, Eunji Cheong et al. · 2015 · Scientific Reports
  52. On the identification of low allele frequency mosaic mutations in the brains of Alzheimer’s disease patients
    Sala Frigerio, Carlo, Lau, Pierre, Troakes, Claire, Deramecourt, Vincent, Gele, Patrick, Van Loo, Peter, Voet, Thierry, De Strooper, Bart · 2015 · Alzheimer's &amp; Dementia
  53. Variably Protease-Sensitive Prionopathy: a Novel Disease of the Prion Protein
    Pierluigi L. Gambetti, Gianfranco Puoti, Wen‐Quan Zou · 2011 · Journal of Molecular Neuroscience
  54. Progression of Alzheimer’s disease, tau propagation, and its modifiable risk factors
    Shuko Takeda · 2018 · Neuroscience Research
  55. Ordered Assembly of Tau Protein and Neurodegeneration
    Michel Goedert, Maria Grazia Spillantini · 2019 · Advances in experimental medicine and biology
  56. Mortalin – a multipotent chaperone regulating cellular processes ranging from viral infection to neurodegeneration
    Zuzana Flachbartova, Branislav Kováčech · 2013 · Acta Virologica
  57. Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model
    Pavan Krishnamurthy, Yan Deng, Einar M. Sigurdsson · 2011 · Frontiers in Psychiatry
  58. Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau
    Irene López‐González, Ester Aso, Margarita Carmona, Mercedes Armand‐Ugón, Rosi Blanco, Alba Naudí, Rosanna Cabré, Manuel Portero‐Otín, Reinald Pamplona, Isidró Ferrer · 2015 · Journal of Neuropathology & Experimental Neurology
  59. Sphingolipid-Enriched Extracellular Vesicles and Alzheimer’s Disease: A Decade of Research
    Michael B. Dinkins, Guanghu Wang, Erhard Bieberich · 2016 · Journal of Alzheimer s Disease
  60. Amplification of Tau Fibrils from Minute Quantities of Seeds
    Virginia Meyer, Paul D. Dinkel, Emily Rickman Hager, Martin Margittai · 2014 · Biochemistry
  61. Physiological and Pathophysiological Implications of Synaptic Tau
    Philip L. Regan, Daniel J. Whitcomb, Kwangwook Cho · 2016 · The Neuroscientist
  62. FTD and ALS—translating mouse studies into clinical trials
    Lars Matthias Ittner, Glenda Margaret Halliday, Jillian J. Kril, Jürgen Götz, John R. Hodges, Matthew C. Kiernan · 2015 · Nature Reviews Neurology
  63. Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
    Manuel Schweighauser, Alexey G. Murzin, Jennifer A. Macdonald, Isabelle Lavenir, R. Anthony Crowther, Sjors H. W. Scheres, Michel Goedert · 2023 · Acta Neuropathologica Communications
  64. Proteins Recruited to Exosomes by Tau Overexpression Implicate Novel Cellular Mechanisms Linking Tau Secretion with Alzheimer's Disease
    Sudad Saman, Norman C.Y. Lee, Itoro E. Inoyo, Jun Jin, Zhihan Li, Thomas Doyle, Ann Carolyn McKee, Garth F. Hall · 2014 · Journal of Alzheimer s Disease
  65. Antisense-mediated Exon Skipping Decreases Tau Protein Expression: A Potential Therapy For Tauopathies
    Reeteka Sud, Evan T. Geller, Gerard D. Schellenberg · 2014 · Molecular Therapy — Nucleic Acids
  66. Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice
    Wencheng Liu, Lingzhi Zhao, Brittany A. Blackman, Mayur S. Parmar, Man Ying Wong, Thomas Woo, Fangmin Yu, Marı́a J. Chiuchiolo, Dolan Sondhi, Stephen M. Kaminsky et al. · 2016 · Journal of Neuroscience
  67. A multilevel view of the development of Alzheimer's Disease.
    J. Ávila, George Perry · 2020 · Neuroscience
  68. Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus–pericoerulear complex by three-dimensional imaging
    Abris Gilvesy, Evelina Husén, Zsófia Maglóczky, Orsolya Salamonné Mihály, Tibor Hortobágyi, Shigeaki Kanatani, Helmut Heinsen, Nicolas Renier, Tomas G. M. Hökfelt, Jan Mulder et al. · 2022 · Acta Neuropathologica
  69. Cross-seeding and Conformational Selection between Three- and Four-repeat Human Tau Proteins
    Xiang Yu, Yin Luo, Paul D. Dinkel, Jie Zheng, Guanghong Wei, Martin Margittai, Ruth Nussinov, Buyong Ma · 2012 · Journal of Biological Chemistry
  70. Prions: Generation and Spread Versus Neurotoxicity
    Mark Halliday, Helois Radford, Giovanna R. Mallucci · 2014 · Journal of Biological Chemistry
  71. Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses
    Anna Wilkaniec, Grzegorz Arkadiusz Czapski, Agata Adamczyk · 2015 · Journal of Neurochemistry
  72. High–Molecular-Weight Paired Helical Filaments from Alzheimer Brain Induces Seeding of Wild-Type Mouse Tau into an Argyrophilic 4R Tau Pathology in Vivo
    Emilie Audouard, Sarah Houben, Caterina Masaracchia, Zehra Yilmaz, Valérie Suain, Michèle Authelet, Robert De Decker, Luc Buée, Alain Boom, Karelle Leroy et al. · 2016 · American Journal Of Pathology
  73. The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau)
    Yin Xu, Sheng Zhang, Hui Zheng · 2018 · Autophagy
  74. Tau immunotherapies for Alzheimer’s disease
    Justin L. Hoskin, Marwan Noel Sabbagh, Yazan M. Al-Hasan, Boris Decourt · 2019 · Expert Opinion on Investigational Drugs
  75. Tau pathology in children and young adults: can you still be unconditionally baptist?
    Charles J. Duyckaerts · 2011 · Acta Neuropathologica
  76. Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta
    Emily Miyoshi, Tina V. Bilousova, Mikhail Melnik, Danyl Fakhrutdinov, Wayne W. Poon, Harry V. Vinters, Carol A. Miller, María M. Corrada, Claudia H. Kawas, Ryan C. Bohannan et al. · 2021 · Laboratory Investigation
  77. The Molecular Pathology of Alzheimer's Disease
    Charles R. Harrington · 2012 · Neuroimaging Clinics of North America
  78. The “Jekyll and Hyde” Actions of Nucleic Acids on the Prion-like Aggregation of Proteins
    Jerson Lima Silva, Yraima Cordeiro · 2016 · Journal of Biological Chemistry
  79. Presence of tau pathology within foetal neural allografts in patients with Huntington’s and Parkinson’s disease
    Giulia Cisbani, Alexander Maxan, Jeffrey H. Kordower, Emmanuel Planel, Thomas B Freeman, Francesca Cicchetti · 2017 · Brain
  80. The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage
    Cecilia Wallin, Yoshitaka Hiruma, Sebastian K.T.S. Wärmländer, Isabelle Huvent, Jüri Jarvet, Jan Pieter Abrahams, Astrid Gräslund, Guy M. Lippens, Jinghui Luo · 2018 · Journal of the American Chemical Society
  81. Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration
    Carlo Scialò, Elena De Cecco, Paolo Manganotti, Giuseppe Legname · 2019 · Viruses
  82. Erratum: De novo induction of amyloid-β deposition in vivo
    Rodrigo Morales, Claudia A. Duran-Aniotz, Joaquı́n Castilla, Lisbell D. Estrada, Claudio A. Soto · 2012 · Molecular Psychiatry
  83. The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties
    Matsumoto, Shin-Ei, Motoi, Yumiko, Ishiguro, Koichi, Tabira, Takeshi, Kametani, Fuyuki, Hasegawa, Masato, Hattori, Nobutaka · 2015 · Human Molecular Genetics
  84. Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit
    Will C. Guest, Judith M. Silverman, Edward Pokrishevsky, Megan A. O’Neill, Leslie I. Grad, Neil R. Cashman · 2011 · Journal of Toxicology and Environmental Health
  85. Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells
    Vinod Sundaramoorthy, Adam K. Walker, Justin J. Yerbury, Kai Ying Soo, Manal A. Farg, Vy Hoang, Rafaa Zeineddine, Damian M. S. Spencer, Julie D. Atkin · 2013 · Cellular and Molecular Life Sciences
  86. Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders
    Masato Hasegawa, Takashi Nonaka, Masami Masuda‐Suzukake · 2016 · Pharmacology & Therapeutics
  87. Recapitulation of Endogenous 4R Tau Expression and Formation of Insoluble Tau in Directly Reprogrammed Human Neurons
    Capano, Lucia S., Sato, Chihiro, Ficulle, Elena, Yu, Anan, Horie, Kanta, Kwon, Ji-Sun, Burbach, Kyle F., Barthélemy, Nicolas R., Fox, Susan G., Karch, Celeste M. et al. · 2022 · Cell Stem Cell
  88. Spinal cord extracts of amyotrophic lateral sclerosis spread TDP-43 pathology in cerebral organoids
    Yoshitaka Tamaki, Jay P. Ross, Paria Alipour, Charles-Etienne Castonguay, Boting Li, Hélène Catoire, Daniel L. Rochefort, Makoto Urushitani, Ryōsuke Takahashi, Joshua Aaron Sonnen et al. · 2023 · PLoS Genetics
  89. Alzheimer’s disease patient brain extracts induce multiple pathologies in novel vascularized neuroimmune organoids for disease modeling and drug discovery
    Yanru Ji, Xiaoling Chen, Zhen Wang, Connor Joseph Meek, Jenna Lillie McLean, Yang Yang, Chongli Yuan, Jean‐Christophe Rochet, Fei Liu, Ranjie Xu · 2025 · Molecular Psychiatry
  90. Prion-like features of misfolded Aβ and tau aggregates
    Rodrigo Morales, Keri Callegari, Claudio A. Soto · 2015 · Virus Research
  91. Three- and Four-repeat Tau Coassemble into Heterogeneous Filaments
    Ayisha Siddiqua, Martin Margittai · 2010 · Journal of Biological Chemistry
  92. Prion-like mechanisms in Alzheimer disease
    Lary C. Walker · 2018 · Handbook of clinical neurology
  93. Models of Network Spread and Network Degeneration in Brain Disorders
    Ashish Raj, Fon Powell · 2018 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
  94. Normal and Pathological Tau Uptake Mediated by M1/M3 Muscarinic Receptors Promotes Opposite Neuronal Changes
    Viktoriya Morozova, Leah S. Cohen, Ali El-Hadi Makki, Alison Shur, Guillermo R. Pilar, Abdeslem El Idrissi, Alejandra del C. Alonso · 2019 · Frontiers in Cellular Neuroscience
  95. The role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseases
    Rafaa Zeineddine, Justin J. Yerbury · 2015 · Frontiers in Physiology
  96. Protein Tau: Prime Cause of Synaptic and Neuronal Degeneration in Alzheimer's Disease
    Natàlia Crespo‐Biel, Clara Theunis, Fred VAN LEUVEN · 2012 · International Journal of Alzheimer s Disease
  97. Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?
    Michael Beekes, Achim Thomzig, Walter Schulz‐Schaeffer, Reinhard Burger · 2014 · Acta Neuropathologica
  98. Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease
    Yijun Xu, Ngan Pan Bennett Au, Chi Him Eddie Ma · 2022 · Frontiers in Aging Neuroscience
  99. Neuronal identity defines α-synuclein and tau toxicity
    Roman Praschberger, Sabine Kuenen, Nils Schoovaerts, Natalie Kaempf, Jeevanjot Singh, Jasper Janssens, Jef Swerts, Eliana Nachman, Carles Calatayud, Stein Aerts et al. · 2023 · Neuron
  100. Downregulation of canonical Wnt signaling in hippocampus of SAMP8 mice
    Sergi Bayod, Paolo Felice, Pol Andrés‐Benito, Paolo Rosa, Antoni Camins, Mercè Pallàs, Anna-Maria Canudas · 2014 · Neurobiology of Aging