Transmission and spreading of tauopathy in transgenic mouse brain

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Items 301–400 of 1,006

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2. Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
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4. Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models
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6. Mechanisms of protein toxicity in neurodegenerative diseases
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7. Widespread tau seeding activity at early Braak stages
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8. NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy
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9. Cell-to-Cell Transmission of Tau and α-Synuclein
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10. Tau Structures
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12. Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia
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13. Tau: From research to clinical development
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14. Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies
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16. Formation and Propagation of Tau Oligomeric Seeds
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17. Nanozyme scavenging ROS for prevention of pathologic α-synuclein transmission in Parkinson’s disease
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18. Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice
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19. Biosensors for Alzheimer's disease biomarker detection: A review
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20. Induction of a transmissible tau pathology by traumatic brain injury
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22. Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
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23. Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits
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24. β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View
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26. Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology
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27. Tau strains shape disease
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28. Cell Cycle Activation and Aneuploid Neurons in Alzheimer's Disease
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29. Acetylation: a new key to unlock tau’s role in neurodegeneration
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30. New Insights Into Drug Discovery Targeting Tau Protein
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31. Tau Oligomers Neurotoxicity
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32. Intercellular Spread of Protein Aggregates in Neurodegenerative Disease
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33. Hyperphosphorylation determines both the spread and the morphology of tau pathology
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34. CB2 Cannabinoid Receptor As Potential Target against Alzheimer's Disease
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35. Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau
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36. Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain
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37. Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
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38. Therapeutic strategies for tau mediated neurodegeneration
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39. “Prion‐Like” Templated Misfolding in Tauopathies
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40. Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases
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41. Interaction between pathogenic proteins in neurodegenerative disorders
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42. Biophysical Insights into How Surfaces, Including Lipid Membranes, Modulate Protein Aggregation Related to Neurodegeneration
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43. Trem2 deletion enhances tau dispersion and pathology through microglia exosomes
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44. Microglia in Alzheimer’s Disease in the Context of Tau Pathology
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45. Tau‐targeted treatment strategies in Alzheimer's disease
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46. Microglial phagocytosis in aging and Alzheimer's disease
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47. In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
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48. P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
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49. The Prion-Like Spreading of Alpha-Synuclein in Parkinson’s Disease: Update on Models and Hypotheses
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51. Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo
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52. Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies
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53. Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein
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54. Connecting the dots between tau dysfunction and neurodegeneration
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55. Mammalian Target of Rapamycin (mTor) Mediates Tau Protein Dyshomeostasis
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56. Experimental transmissibility of mutant SOD1 motor neuron disease
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57. Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer’s disease
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58. Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets
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59. Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets
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60. Cell Death and Neurodegeneration
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61. Thinking laterally about neurodegenerative proteinopathies
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62. TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading
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63. The Role of Tau Oligomers in the Onset of Alzheimer's Disease Neuropathology
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64. Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study
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65. Neuropathogenesis-on-chips for neurodegenerative diseases
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66. Pathogenesis of the Tauopathies
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67. Propagation of Tau via Extracellular Vesicles
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68. Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer’s Disease Pathogenesis
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69. Alzheimer disease
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70. Spreading of α-Synuclein and Tau: A Systematic Comparison of the Mechanisms Involved
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71. Potential Contribution of Exosomes to the Prion-Like Propagation of Lesions in Alzheimer’s Disease
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73. Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease
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74. Astroglia and Tau: New Perspectives
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75. AADvac1, an Active Immunotherapy for Alzheimer's Disease and Non Alzheimer Tauopathies: An Overview of Preclinical and Clinical Development
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77. TGF-β1 signalling in Alzheimer’s pathology and cytoskeletal reorganization: a specialized Tau perspective
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78. Circadian clocks and neurodegenerative diseases: time to aggregate?
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79. Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients
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81. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy
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82. Degradation and Transmission of Tau by Autophagic-Endolysosomal Networks and Potential Therapeutic Targets for Tauopathy
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83. Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases
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88. Spreading of tau pathology in A lzheimer's disease by cell‐to‐cell transmission
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90. Glial Tau Pathology in Tauopathies: Functional Consequences
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95. Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau
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96. Galectin-8–mediated selective autophagy protects against seeded tau aggregation
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97. Different tau species lead to heterogeneous tau pathology propagation and misfolding
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99. Interneuronal Transfer of Human Tau Between Lamprey Central Neurons in situ
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100. Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease
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