Transmission and spreading of tauopathy in transgenic mouse brain

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3. Prion-like acceleration of a synucleinopathy in a transgenic mouse model
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4. Amyloid-β and tau complexity — towards improved biomarkers and targeted therapies
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5. The complexity of tau in Alzheimer’s disease
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6. Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
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7. Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain
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8. The Seeds of Neurodegeneration: Prion-like Spreading in ALS
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9. Alzheimer’s disease is not “brain aging”: neuropathological, genetic, and epidemiological human studies
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10. Sporadic human prion diseases: molecular insights and diagnosis
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11. Neurodegenerative Diseases: Expanding the Prion Concept
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12. Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions
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13. Alzheimer’s pathogenesis: is there neuron-to-neuron propagation?
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14. <i>In Vivo</i> Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
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15. Tau and neuroinflammation: what impact for Alzheimer's disease and tauopathies?
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16. Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models
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17. Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission
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18. Immune Signaling in Neurodegeneration
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19. Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
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20. Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
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21. Seeded Aggregation and Toxicity of α-Synuclein and Tau
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22. Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease
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23. Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration
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24. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
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25. Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network
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26. Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies?
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27. PART is part of Alzheimer disease
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28. Tau Oligomers: Cytotoxicity, Propagation, and Mitochondrial Damage
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29. Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)
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30. Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer’s disease (MCI and dementia) in primary care: a review and synthesis
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31. Propagation of Protein Aggregation in Neurodegenerative Diseases
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32. RNA stores tau reversibly in complex coacervates
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33. Cell-to-cell transmission of non-prion protein aggregates
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34. Passive immunization targeting pathological phospho‐tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
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35. Mechanisms of secretion and spreading of pathological tau protein
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36. Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases
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37. Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant
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38. Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles
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39. Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders
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40. Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids
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41. Alpha-synuclein and tau: teammates in neurodegeneration?
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42. Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration
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43. A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration
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44. Monoaminergic neuropathology in Alzheimer’s disease
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45. Prion-like disorders: blurring the divide between transmissibility and infectivity
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46. Exosomes in the Pathology of Neurodegenerative Diseases
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47. Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer’s Disease Brain
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48. Immunotherapeutic Approaches for Alzheimer’s Disease
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49. Are synucleinopathies prion-like disorders?
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50. Role of tau protein in Alzheimer’s disease: The prime pathological player
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52. Antisense oligonucleotides: translation from mouse models to human neurodegenerative diseases
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53. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
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54. Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model
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55. Lost after translation: missorting of Tau protein and consequences for Alzheimer disease
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56. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner
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57. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals
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58. Genetic Analysis of Pathways to Parkinson Disease
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59. Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation
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60. Cryo-EM structures of tau filaments
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61. Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies
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62. Tau-aggregation inhibitor therapy for Alzheimer's disease
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63. Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
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64. Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART
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65. Molecular nexopathies: a new paradigm of neurodegenerative disease
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66. Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains
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67. Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
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68. Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation
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69. Models of β-amyloid induced Tau-pathology: The long and “folded” road to understand the mechanism
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70. Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins
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71. TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading
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72. Misfolded protein aggregates: Mechanisms, structures and potential for disease transmission
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73. Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates
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74. Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
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75. Tau Proteins and Tauopathies in Alzheimer’s Disease
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76. Tau immunotherapy for Alzheimer's disease
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77. P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating
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78. Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells
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79. Cellular and pathological functions of tau
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80. Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid
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81. Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
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82. Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody
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83. Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy
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84. CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges
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85. Protein misfolding and aggregation in Alzheimer’s disease and type 2 diabetes mellitus
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86. Distinct profiles of brain atrophy in frontotemporal lobar degeneration caused by progranulin and tau mutations
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87. Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo
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88. Functional connectivity associated with tau levels in ageing, Alzheimer’s, and small vessel disease
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89. GABAergic dysfunction in excitatory and inhibitory (E/I) imbalance drives the pathogenesis of Alzheimer's disease
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90. Soluble forms of tau are toxic in Alzheimer's disease
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91. Emerging Concepts in Alzheimer's Disease
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92. A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies
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95. Developing Therapeutic Antibodies for Neurodegenerative Disease
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96. Mechanisms of Protein Seeding in Neurodegenerative Diseases
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97. Constitutive secretion of tau protein by an unconventional mechanism
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98. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
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99. Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections
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