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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI

Chaudhury, Arindam, Hussey, George S., Ray, Partho S, Jin, Ge, Fox, Paul L., Howe, Philip H.·2010·Nature Cell Biology
DOI 10.1038/ncb2029PMC PMC2830561
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  • Several mechanisms have been suggested for Dab2 involvement in the TGF-beta pathway, but their actual operation in intact animals and physiological settings has yet to be demonstrated.

    “Thus, several mechanisms have been suggested for the involvement of Dab2 in TGF-beta pathway, such as receptor recycling, adapting function for Smad activation, or non-canonical TGF-beta signaling through the Ras-MAPK pathway, although the actual operation of these mechanisms in intact animals and physiological settings have yet to be demonstrated.”

    From Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice (2016) · cites this paper as Chaudhury et al., 2010

    The paper’s Abstract describes Dab2 as a mediator of TGF-β-induced EMT and says its precise function downstream of hnRNP E1 is difficult to define. It does not identify receptor recycling, Smad activation, or Ras–MAPK signaling as proposed Dab2 mechanisms, nor does it specifically say that those mechanisms remain untested in intact animals or physiological settings. No page number is available in our copy. (LLM, conf=0.79)

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Research works printed but not linked: 33

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  9. Waerner, T. et al. ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell 10, 227–239 (2006). · DOI
  10. Greinwald, J. H. Jr et al. Localization of a novel gene for nonsyndromic hearing loss (DFNB17) to chromosome region 7q31. Am. J. Med. Genet. 78, 107–113 (1998). · DOI
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  17. Kattla, J. J., Carew, R. M., Heljic, M., Godson, C. & Brazil, D. P. Protein kinase B/Akt activity is involved in renal TGF-β1-driven epithelial–mesenchymal transition in vitro and in vivo. Am. J. Physiol. Renal Physiol. 295, F215–F225 (2008). · DOI
  18. Kato, M. et al. TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nature Cell Biol. 11, 881–889 (2009). · DOI
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Metadata

Authors
Chaudhury, A., Hussey, G. S., Ray, P. S., Jin, G., Fox, P. L., & Howe, P. H.
Venue
Nature Cell Biology
Publisher
Springer Science and Business Media LLC
Published
2010-02-14
Volume
12
Issue
3
Pages
286-293
ISSN
  • 1465-7392
  • 1476-4679
DOI
10.1038/ncb2029
PMC
PMC2830561
Cited by
270
References
3
Language
en
Licence
www.springer.com/tdm (tdm)

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