The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

Jun, Joon-Il, Lau, Lester F.·2010·Nature Cell Biology
DOI 10.1038/ncb2070

Cited by (134)

Items 101–134 of 134

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  2. The right time for senescence
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  3. Systemic DNA damage responses in aging and diseases
    Ribezzo, Flavia, Shiloh, Yosef, Schumacher, Björn · 2016 · Seminars in Cancer Biology
  4. The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
    Xu, Peng, Wang, Minghui, Song, Won-min, Wang, Qian, Yuan, Guo-Cheng, Sudmant, Peter H., Zare, Habil, Tu, Zhidong, Orr, Miranda E., Zhang, Bin · 2022 · Molecular Neurodegeneration
  5. Scarless wound healing: From development to senescence
    Pratsinis, Harris, Mavrogonatou, Eleni, Kletsas, Dimitris · 2019 · Advanced Drug Delivery Reviews
  6. Regulation of senescence and the SASP by the transcription factor C/EBPβ
    Salotti, Jacqueline, Johnson, Peter F. · 2019 · Experimental Gerontology
  7. Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research Questions
    Tripathi, Utkarsh, Misra, Avanish, Tchkonia, Tamar, Kirkland, James L. · 2021 · Mechanisms of Ageing and Development
  8. To clear, or not to clear (senescent cells)? That is the question
    Lujambio, Amaia · 2016 · BioEssays
  9. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling
    Borkham-Kamphorst, Erawan, Schaffrath, Christian, Van de Leur, Eddy, Haas, Ute, Tihaa, Lidia, Meurer, Steffen K., Nevzorova, Yulia A., Liedtke, Christian, Weiskirchen, Ralf · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  10. Cellular senescence and tumor promotion: Is aging the key?
    Loaiza, Natalia, Demaria, Marco · 2016 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  11. Novel insights from a multiomics dissection of the Hayflick limit
    Chan, Michelle, Yuan, Han, Soifer, Ilya, Maile, Tobias M, Wang, Rebecca Y, Ireland, Andrea, O'Brien, Jonathon J, Goudeau, Jérôme, Chan, Leanne JG, Vijay, Twaritha et al. · 2022 · eLife
  12. Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2
    Cheng, Naiyuan, Kim, Ki-Hyun, Lau, Lester F. · 2022 · JCI Insight
  13. Short-term gain, long-term pain: the senescence life cycle and cancer
    Chan, Adelyne Sue Li, Narita, Masashi · 2019 · Genes & Development
  14. Non-cell autonomous effects of the senescence-associated secretory phenotype in cancer therapy.
    Saleh, Tareq, Tyutynuk-Massey, Liliya, Cudjoe, Emmanuel K., Idowu, Michael O., Landry, Joseph W., Gewirtz, David A. · 2018 · Frontiers in Oncology
  15. ATF3 drives senescence by reconstructing accessible chromatin profiles
    Zhang, Chao, Zhang, Xuebin, Huang, Li, Guan, Yiting, Huang, Xiaoke, Tian, Xiao‐Li, Zhang, Lijun, Tao, Wei · 2021 · Aging Cell
  16. Cellular Senescence as a Therapeutic Target for Age-Related Diseases: A Review
    Amaya-Montoya, Mateo, Pérez-Londoño, Agustín, Guatibonza-García, Valentina, Vargas-Villanueva, Andrea, Mendivil, Carlos O. · 2020 · Advances in Therapy
  17. Mitochondrial DNA damage induces apoptosis in senescent cells
    Laberge, R-M, Adler, D, DeMaria, M, Mechtouf, N, Teachenor, R, Cardin, G B, Desprez, P-Y, Campisi, J, Rodier, F · 2013 · Cell Death & Disease
  18. Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells
    Velarde, Michael C., Demaria, Marco, Melov, Simon, Campisi, Judith · 2015 · Proceedings of the National Academy of Sciences
  19. Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts
    Razdan, Neetu, Vasilopoulos, Themistoklis, Herbig, Utz · 2018 · Aging Cell
  20. Targeting senescent cells improves functional recovery after spinal cord injury
    Paramos-de-Carvalho, Diogo, Martins, Isaura, Cristóvão, Ana Margarida, Dias, Ana Filipa, Neves-Silva, Dalila, Pereira, Telmo, Chapela, Diana, Farinho, Ana, Jacinto, António, Saúde, Leonor · 2021 · Cell Reports
  21. Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro
    Mária, Janubová, Ingrid, Žitňanová · 2017 · Food & Function
  22. Targeting senescent cells: possible implications for delaying skin aging: a mini-review
    Velarde, Michael C., Demaria, Marco · 2016 · Gerontology
  23. Geroconversion of aged muscle stem cells under regenerative pressure
    Sousa-Victor, Pedro, Perdiguero, Eusebio, Muñoz-Cánoves, Pura · 2014 · Cell Cycle
  24. Targeting aging and age-related diseases with vaccines
    Wu, Ruochen, Sun, Fei, Zhang, Weiqi, Ren, Jie, Liu, Guang-Hui · 2024 · Nature Aging
  25. Roadmap for alleviating the manifestations of ageing in the cardiovascular system
    Liberale, Luca, Tual-Chalot, Simon, Sedej, Simon, Ministrini, Stefano, Georgiopoulos, Georgios, Grunewald, Myriam, Bäck, Magnus, Bochaton-Piallat, Marie-Luce, Boon, Reinier A., Ramos, Gustavo Campos et al. · 2025 · Nature Reviews Cardiology
  26. Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain
    Santoro, Antonietta, Spinelli, Chiara Carmela, Martucciello, Stefania, Nori, Stefania Lucia, Capunzo, Mario, Puca, Annibale Alessandro, Ciaglia, Elena · 2018 · Journal of Leukocyte Biology
  27. Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration
    Yu, Qinghao, Walters, Hannah E., Pasquini, Giovanni, Pal Singh, Sumeet, Lachnit, Martina, Oliveira, Catarina R., León-Periñán, Daniel, Petzold, Andreas, Kesavan, Preethi, Subiran Adrados, Cristina et al. · 2023 · Developmental Cell
  28. MicroRNAs, Long Non-Coding RNAs, and Circular RNAs in the Redox Control of Cell Senescence
    Lettieri-Barbato, Daniele, Aquilano, Katia, Punziano, Carolina, Minopoli, Giuseppina, Faraonio, Raffaella · 2022 · Antioxidants
  29. Senescent cells enhance newt limb regeneration by promoting muscle dedifferentiation
    Walters, Hannah E., Troyanovskiy, Konstantin E., Graf, Alwin M., Yun, Maximina H. · 2023 · Aging Cell
  30. Context‐dependent roles of cellular senescence in normal, aged, and disease states
    Moiseeva, Victoria, Cisneros, Andrés, Cobos, Aina Calls, Tarrega, Aida Beà, Oñate, Claudia Santos, Perdiguero, Eusebio, Serrano, Antonio L., Muñoz‐Cánoves, Pura · 2023 · The FEBS Journal
  31. Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis
    Mooring, Meghan, Yeung, Grace A., Luukkonen, Panu, Liu, Silvia, Akbar, Muhammad Waqas, Zhang, Gary J., Balogun, Oluwashanu, Yu, Xuemei, Mo, Rigen, Nejak-Bowen, Kari et al. · 2023 · Science Translational Medicine
  32. Cellular Senescence in Chronic Obstructive Pulmonary Disease: Multifaceted and Multifunctional
    Antony, Veena B., Thannickal, Victor J. · 2018 · American Journal of Respiratory Cell and Molecular Biology
  33. Cellular communication network factor 1‐stimulated liver macrophage efferocytosis drives hepatic stellate cell activation and liver fibrosis
    Kim, Ki‐Hyun, Cheng, Naiyuan, Lau, Lester F. · 2022 · Hepatology Communications
  34. Stress-induced cellular senescence contributes to chronic inflammation and cancer progression.
    KOBASHIGAWA, SHINKO, M. SAKAGUCHI, YOSHIHIKO, MASUNAGA, SHINICHIRO, MORI, EIICHIRO · 2019 · Thermal Medicine