The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Mihaylova, Maria M., Shaw, Reuben J.·2011·Nature Cell Biology

DOI 10.1038/ncb2329

Cited by (1,012)

Items 601–700 of 1,012

Metformin: Insights into its anticancer potential with special reference to AMPK dependent and independent pathways
Shoeb Ikhlas, Masood Ahmad · 2017 · Life Sciences
Akt/mTOR Role in Human Foetoplacental Vascular Insulin Resistance in Diseases of Pregnancy
Roberto Villalobos-Labra, Luis Silva, Mario Subiabre, Joaquín Araos Henríquez, Rocío Salsoso, Bárbara Fuenzalida, Tamara Sáez, Fernando Toledo, Marcelo González, Claudia Quezada et al. · 2017 · Journal of Diabetes Research
AMPK–Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation
Manipa Saha, Saurav Kumar, Shoiab Bukhari, Sai Balaji Andugulapati, Prashant Kumar, Sravanth Kumar Hindupur, Annapoorni Rangarajan · 2018 · Cancer Research
6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming
Chen Hu, Dongde Wu, Lequn Bao, Tao Yin, Dansheng Lei, Jing Yu, Xianli Tong · 2019 · Biomedicine & Pharmacotherapy
The effect of adipocyte–macrophage crosstalk in obesity-related breast cancer
Ayşe Başak Engin, Atilla Engin, İpek Işık Gönül · 2019 · Journal of Molecular Endocrinology
Cardiomyocyte health: adapting to metabolic changes through autophagy
Dieter A. Kubli, Åsa B. Gustafsson · 2013 · Trends in Endocrinology and Metabolism
Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment
Hitoshi Endo, Satoshi Owada, Yutaka Inagaki, Yukari Shida, Masayuki Tatemichi · 2020 · Redox Biology
Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
Liemei Guo, Jing Cui, Herui Wang, Rogelio Medina, Shilei Zhang, Xiaohua Zhang, Zhengping Zhuang, Yingying Lin · 2020 · Molecular Therapy — Oncolytics
Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling
Chenchu Lin, Alicia Marie Blessing, Thomas L. Pulliam, Yan Shi, Sandi R. Wilkenfeld, Jenny J. Han, Mollianne M. Murray, Alexander H. Pham, Kevin Duong, Sonja N. Brun et al. · 2021 · Oncogene
Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response
Victor Samokhvalov, Nasser B. Alsaleh, Haitham E. El-Sikhry, K. Lockhart Jamieson, C B Chen, David G. Lopaschuk, C Carter, Peter E. Light, Rahul Manne, John Russell Falck et al. · 2013 · Cell Death and Disease
Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells
Shu-Feng Zhou, Feng Wang, Qi Wang, Zhi-Wei Zhou, N Song, Shuting Pan, Zhixu He, Xueji Zhang, Dong Wang, Yinxue Yang et al. · 2015 · Drug Design Development and Therapy · Retracted
Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma
Yashwanth Subbannayya, Nazia Syed, Mustafa Ahmed Barbhuiya, Remya Raja, Arivusudar Marimuthu, Nandini A. Sahasrabuddhe, Sneha Maria Pinto, Srikanth Srinivas Manda, Santosh Renuse, H. C. Manju et al. · 2015 · Cancer Biology & Therapy
Atorvastatin ameliorates LPS‐induced inflammatory response by autophagy via AKT/mTOR signaling pathway
Fei Han, Qingqing Xiao, Shi Peng, Xinyu Che, Li‐Sheng Jiang, Qin Shao, Ben He · 2017 · Journal of Cellular Biochemistry
Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling
Bing Han, Yiqun Yu, Qilian Yang, Chunying Shen, Xiaojuan Wang · 2017 · Oncotarget
Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect
Tia Tidwell, Kjetil Søreide, Hanne Røland Hagland · 2017 · Aging and Disease
Autophagy and mitochondrial biogenesis impairment contribute to age‐dependent liver injury in experimental sepsis: dysregulation of AMP‐activated protein kinase pathway
Yu Inata, Satoshi Kikuchi, Ravi Shankar Samraj, Paul W. Hake, Michael O’Connor, John R. Ledford, James O'Connor, Patrick M. Lahni, Vivian Wolfe, Giovanna Piraino et al. · 2017 · The FASEB Journal
Advances in Age-related Macular Degeneration Understanding and Therapy
Joan W. Miller, Saghar Bagheri, Demetrios G. Vavvas · 2017 · touchREVIEWS in Ophthalmology
Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells
Ankit Sharma, Shreetama Bandyopadhayaya, Kaushik Chowdhury, Tanu Sharma, Rekha Maheshwari, Amlan Kumar Das, Gopal Chakrabarti, Vipin Kumar, Chandi Charan Mandal · 2019 · PLoS ONE
Metformin promotes autophagy in ischemia/reperfusion myocardium via cytoplasmic AMPKα1 and nuclear AMPKα2 pathways
Yishi Wang, Zheng Yang, Guoxu Zheng, Lu Yu, Yue Yin, Nan Mu, Heng Ma · 2019 · Life Sciences
Salinomycin and its derivatives – A new class of multiple-targeted “magic bullets”
Michał Antoszczak, Adam Huczyński · 2019 · European Journal of Medicinal Chemistry
Targeting cellular cholesterol for anticancer therapy
Liang Gu, Sourav Taru Saha, Jodie Thomas, Mandeep Kaur · 2019 · FEBS Journal
Nitrogen-dependent coordination of cell cycle, quiescence and TAG accumulation in Chlamydomonas
Tomomi Takeuchi, Christoph Benning · 2019 · Biotechnology for Biofuels
Enhanced autophagy contributes to protective effects of IL-22 against acetaminophen-induced liver injury
Ruidong Mo, Rongtao Lai, Jie Li Lu, Yan Zhuang, Tianhui Zhou, Shaowen Jiang, Peipei Ren, Ziqiang Li, Zhujun Cao, Yuhan Liu et al. · 2018 · Theranostics
Sulforaphane induces lipophagy through the activation of AMPK-mTOR-ULK1 pathway signaling in adipocytes
Masashi Masuda, Risa Yoshida-Shimizu, Yuki Mori, Kohta Ohnishi, Yuichiro Adachi, Maiko Sakai, Serina Kabutoya, Hirokazu Ohminami, Hisami Yamanaka‐Okumura, Hironori Yamamoto et al. · 2022 · The Journal of Nutritional Biochemistry
The protective effects of flavonoids and carotenoids against diabetic complications—A review of in vivo evidence
Yannan Jin, Randolph Arroo · 2023 · Frontiers in Nutrition
“Rewiring brain immunity: targeting microglial metabolism for neuroprotection in neurodegenerative disorders”
Mustafa M Shokr · 2025 · Metabolic Brain Disease
Mitochondria-Mediated Energy Adaption in Cancer: The H + -ATP Synthase-Geared Switch of Metabolism in Human Tumors
María Sánchez‐Aragó, Laura Formentini, Jose Manuel Cuezva · 2012 · Antioxidants and Redox Signaling
Deguelin Induces Both Apoptosis and Autophagy in Cultured Head and Neck Squamous Cell Carcinoma Cells
Yanli Yang, Chao Ji, BI Zhi-gang, Chuncheng Lu, Rong Wang, Bing Gu, Lei Cheng · 2013 · PLoS ONE
TAK1 activates AMPK-dependent cell death pathway in hydrogen peroxide-treated cardiomyocytes, inhibited by heat shock protein-70
Zhiyu Chen, Xiaolu Shen, Feng-Yan Shen, Wei Zhong, Hai Wu, Sha Liu, Lai Jiang · 2013 · Molecular and Cellular Biochemistry
Non-cytotoxic copper overload boosts mitochondrial energy metabolism to modulate cell proliferation and differentiation in the human erythroleukemic cell line K562
Lina María Ruíz, Erik L. Jensen, Yancing Rossel Mutis, German I. Puas, Alvaro M. Gonzalez-Ibañez, Rodrigo I. Bustos, David A. Ferrick, Álvaro A. Elorza · 2016 · Mitochondrion
The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications
Enrico Girardi, Monica Sañé Schepisi, Delia Goletti, Matthew Bates, Peter Mwaba, Dorothy Yeboah‐Manu, Francine Ntoumi, Fabrizio Palmieri, Markus J. Maeurer, Alimuddin I. Zumla et al. · 2017 · International Journal of Infectious Diseases
Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells
Shinwon Ha, Seol-Hwa Jeong, Kyungrim Yi, Kyung Min Chung, Caroline Jeeyeon Hong, Seong Who Kim, Eun‐Kyoung Kim, Seong‐Woon Yu · 2017 · Journal of Biological Chemistry
Metabolic Adaptations of CD4+ T Cells in Inflammatory Disease
Cristina Dumitru, Agnieszka Martyna Kabat, Kevin Joseph Maloy · 2018 · Frontiers in Immunology
Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities
Muhammad Assad Riaz, Ali Sak, Yasin Bahadir Erol, Michael Groneberg, Jürgen Thomale, Martin Stuschke · 2019 · Scientific Reports
Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
Krystyna Cwiklinski, Mark W. Robinson, Sheila Donnelly, John P. Dalton · 2021 · BMC Genomics
Metformin Inhibits the Type 1 IFN Response in Human CD4+ T Cells
Anton A. Titov, Henry V. Baker, Todd M. Brusko, Eric S. Sobel, Laurence M Morel · 2019 · The Journal of Immunology
Phosphofructokinase P fine-tunes T regulatory cell metabolism, function, and stability in systemic autoimmunity
Marc Scherlinger, Wenliang Pan, Ryo Hisada, Afroditi Boulougoura, Nobuya Yoshida, Milena Vukelic, Masataka Umeda, Suzanne Krishfield, Maria Tsokos, George C. Tsokos · 2022 · Science Advances
Targeting the LKB1 Tumor Suppressor
Rui–Xun Zhao, Zhi‐Xiang Xu · 2014 · Current Drug Targets
Oxidative Stress in the Hypothalamus: the Importance of Calcium Signaling and Mitochondrial ROS in Body Weight Regulation
Erika Gyengési, George Paxinos, Zane Bruce Andrews · 2012 · Current Neuropharmacology
Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo
Annalisa Bonifacio, Peter J. Mullen, Ileana Scurtu Mityko, Luiz Carlos Carvalho Navegantes, Jamal Bouitbir, Stephan Krähenbühl · 2014 · Archives of Toxicology
WIP1, a Homeostatic Regulator of the DNA Damage Response, Is Targeted by HIPK2 for Phosphorylation and Degradation
Dong Wook Choi, Wooju Na, Mohammad Humayun Kabir, Eunbi Yi, Seonjeong Kwon, Jeonghun Yeom, Jang-Won Ahn, Hee-Hyun Choi, Youngha Lee, Kyoung‐Wan Seo et al. · 2013 · Molecular Cell
Effects of sleeve gastrectomy and ileal transposition, alone and in combination, on food intake, body weight, gut hormones, and glucose metabolism in rats
Sidrah Nausheen, I. H. Shah, Adel Pezeshki, David L. Sigalet, Prasanth K. Chelikani · 2013 · American Journal of Physiology-Endocrinology and Metabolism
Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish
Bingyuan Yang, Gang Zhai, Yulong Gong, Jingzhi Su, Xuyan Peng, Guo-Hui Shang, Dong Ho Han, Junyan Jin, Haokun Liu, Zhen‐Yu Du et al. · 2018 · American Journal of Physiology-Endocrinology and Metabolism
Exosomes, the message transporters in vascular calcification
Chao Zhang, Kun Zhang, Feifei Huang, Weijing Feng, Jie Chen, Huanji Zhang, Jingfeng Wang, Pei Luo, Hui Huang · 2018 · Journal of Cellular and Molecular Medicine
Fisetin Inhibits Autophagy in HepG2 Cells via PI3K/Akt/mTOR and AMPK Pathway
Kiruthika Sundarraj, Azhwar Raghunath, Lakshmikanthan Panneerselvam, Ekambaram Perumal · 2020 · Nutrition and Cancer
Management of anemia of inflammation in the elderly
Macciò, Antonio, Madeddu, Clelia · 2012 · Anemia
Activating AMP-activated protein kinase by an α1 selective activator compound 13 attenuates dexamethasone-induced osteoblast cell death
Shiguang Guo, Li Mao, Feng Ji, Shouguo Wang, Yue Xie, Haodong Fei, Xiaodong Wang · 2016 · Biochemical and Biophysical Research Communications
Systemic therapy for advanced hepatocellular carcinoma: an update
Jasmin Radhika Desai, Sebastian Ochoa, Petra Prins, Aiwu Ruth He · 2017 · Journal of Gastrointestinal Oncology
Insulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485 Phosphorylation
Bhumsoo Kim, Claudia Figueroa‐Romero, Crystal M. Pacut, Carey Backus, Eva L. Feldman · 2015 · Journal of Biological Chemistry
AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain
Santosh Ramamurthy, Gabriele V. Ronnett · 2012 · Experimental Neurobiology
LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small-cell lung cancer (NSCLC) cells
Young Mi Whang, Serk In Park, Irina A. Trenary, Robert A. Egnatchik, Joshua P. Fessel, Jennifer Kaufman, David Paul Carbone, Jamey D. Young · 2015 · Oncogene
Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation
Yukiko Hasumi, Masaya Baba, Hisashi Hasumi, Ying Kao Huang, Martin Lang, Rachel Reindorf, HyoungBin Oh, Sebastiano Sciarretta, Kunio Nagashima, Diana C. Haines et al. · 2014 · Human Molecular Genetics
The Emerging Role of Adiponectin in Female Malignancies
Luca Gelsomino, Giuseppina Daniela Naimo, Stefania Catalano, Loredana Mauro, Sebastiano Andò · 2019 · International Journal of Molecular Sciences
Metformin: A metabolic disruptor and anti-diabetic drug to target human leukemia
Célia Rosilio, Issam Ben‐Sahra, Frédéric Bost, Jean‐François Peyron · 2014 · Cancer Letters
Biological Functions and Therapeutic Potential of Autophagy in Spinal Cord Injury
Hai-Yang Liao, Zhi-Qiang Wang, Rui Ran, Kai‐Sheng Zhou, Chun-Wei Ma, Haihong Zhang · 2021 · Frontiers in Cell and Developmental Biology
Transcriptome Reveals Granulosa Cells Coping through Redox, Inflammatory and Metabolic Mechanisms under Acute Heat Stress
Abdul Sammad, Hanpeng Luo, Lirong Hu, Huabin Zhu, Yachun Wang · 2022 · Cells
Dietary Restriction and Nutrient Balance in Aging
Júlia Santos, Fernanda Leitão-Correia, Maria João Sousa, Cecı́lia Leão · 2015 · Oxidative Medicine and Cellular Longevity
Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells
Han Min, Min Xu, Zhirong Chen, Jundong Zhou, Min Huang, Kai Zheng, Xiaoping Zou · 2014 · Cancer Chemotherapy and Pharmacology
Additive Effects of Nicotine and High-Fat Diet on Hepatic Steatosis in Male Mice
Theodore C. Friedman, Indrani Sinha‐Hikim, Meher Parveen, Sonia Michael Najjar, Yanjun Liu, Michael Mangubat, Chang‐Sung Shin, Alexei Lyzlov, Rasheed Ivey, Magda A. Shaheen et al. · 2012 · Endocrinology
Metabolic control of signalling pathways and metabolic auto‐regulation
Doriane Lorendeau, Stefan Christen, Gianmarco Rinaldi, Sarah‐Maria Fendt · 2015 · Biology of the Cell
The impact of endurance exercise on global and AMPK gene-specific DNA methylation
Tanya S. King-Himmelreich, Stefanie Schramm, Miriam C. Wolters, Julia Schmetzer, Christine V. Möser, Claudia Knothe, Eduard Resch, Johannes Peil, Gerd Geißlinger, Ellen Niederberger · 2016 · Biochemical and Biophysical Research Communications
Swertiamarin ameliorates oleic acid induced lipid accumulation and oxidative stress by attenuating gluconeogenesis and lipogenesis in hepatic steatosis
Tushar P Patel, Komal Rawal, Sanket Soni, Sarita S. Gupta · 2016 · Biomedicine & Pharmacotherapy
NFE2L2/NRF2 Activity Is Linked to Mitochondria and AMP-Activated Protein Kinase Signaling in Cancers Through miR-181c/Mitochondria-Encoded Cytochrome c Oxidase Regulation
Kyeong-Ah Jung, Sujin Lee, Mi‐Kyoung Kwak · 2017 · Antioxidants and Redox Signaling
Amelioration of High Fructose-Induced Cardiac Hypertrophy by Naringin
Jung Hyun Park, Hyeong Jun Ku, Jae Kyeom Kim, Jeen‐Woo Park, Jin Hyup Lee · 2018 · Scientific Reports
The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling
Fabiana Csukasi, Iván Durán, Maya Barad, Tomáš Bárta, Iva Gudernová, Lukáš Trantı́rek, Jorge H Martin, Caroline Y. Kuo, Jeremy D. Woods, Hane Lee et al. · 2018 · Science Translational Medicine
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
Deng, Zhiqiang, Dong, Yu, Zhou, Xiaoting, Lu, Jia-Hong, Yue, Zhenyu · 2022 · Acta Pharmaceutica Sinica B
Cellular Stress and General Pathological Processes
Eugeny Yu. Gusev, Natalia V. Zotova · 2019 · Current Pharmaceutical Design
Fully armed photodynamic therapy with spear and shear for topical deep hypertrophic scar treatment
Yao Huang, Tingting Peng, Wanshan Hu, Xinyi Gao, Yangyan Chen, Qian Zhang, Chuanbin Wu, Xin Pan · 2022 · Journal of Controlled Release
Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway
Qi Liang, Rongjie Guo, Jia-Ruei Tsao, Yun He, Chenchen Wang, Jiaxuan Jiang, Di Zhang, Taige Chen, Tingting Yue, Kai Hu · 2023 · International Immunopharmacology
Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors: a review
Manuel Humberto Cháirez‐Ramírez, Martha Rocío Moreno‐Jiménez, Rubén Francisco González‐Laredo, José Alberto Gallegos‐Infante, Nuria Elizabeth Rocha‐Guzmán · 2016 · EXCLI journal
Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling
Yajing Wang, Bin Liang, Wayne Bond Lau, Yunhui Du, Rui Guo, Zheyi Yan, Lu Gan, Wenjun Yan, Jianli Zhao, Erhe Gao et al. · 2017 · Autophagy
Cellular Metabolism and Aging
André Catic · 2018 · Progress in molecular biology and translational science
Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review
Cara Tomas, Julia L. Newton · 2018 · Biochemical Society Transactions
SIRT1-targeted miR-543 autophagy inhibition and epithelial–mesenchymal transition promotion in Helicobacter pylori CagA-associated gastric cancer
Yanyan Shi, Ziwei Yang, Ting Zhang, Lijuan Shen, Yuan Li, Shigang Ding · 2019 · Cell Death and Disease
Antitumor Activity of Pt(II), Ru(III) and Cu(II) Complexes
Katarzyna Gałczyńska, Zuzanna Drulis‐Kawa, Michał Arabski · 2020 · Molecules
Therapeutic Intervention in Cancer by Isoliquiritigenin from Licorice: A Natural Antioxidant and Redox Regulator
Zhu Zhang, Ken Kin Lam Yung, Joshua Ka-Shun Ko · 2022 · Antioxidants
Signaling pathways involved in paraquat-induced pulmonary toxicity: Molecular mechanisms and potential therapeutic drugs
Xianbo Liu, He Yang, Zhenning Liu · 2022 · International Immunopharmacology
Impact of polyphenols on heart failure and cardiac hypertrophy: clinical effects and molecular mechanisms
Neda Hedayati, Alireza Yaghoobi, Marziyeh Salami, Yasaman Gholinezhad, Farnaz Aghadavood, Reza Eshraghi, Mohammad Hossein Aarabi, Mina Homayoonfal, Zatollah Asemi, Hamed Mirzaei et al. · 2023 · Frontiers in Cardiovascular Medicine
Lifestyle effects on aging and CVD: A spotlight on the nutrient-sensing network
Kaiying Yang, Rongyao Hou, Jie Zhao, Xia Wang, Jin Wei, Xudong Pan, Xiaoyan Zhu · 2023 · Ageing Research Reviews
Diabetes and Osteoarthritis: Exploring the Interactions and Therapeutic Implications of Insulin, Metformin, and GLP-1-Based Interventions
Iryna Halabitska, Л. С. Бабинец, Valentyn Oksenych, Oleksandr Kamyshnyi · 2024 · Biomedicines
Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy
Simone Patergnani, Sonia Missiroli, Saverio Marchi, Carlotta Giorgi · 2015 · Frontiers in Oncology
SNP variation in the promoter of the PRKAG3gene and association with meat quality traits in pig
Marion T. Ryan, Ruth M. Hamill, Aisling M O’Halloran, Grace C. Davey, Jean McBryan, Anne Maria Mullen, Chris McGee, Marina Gispert, O. I. Southwood, Torres Sweeney · 2012 · BMC Genetics
Conceptual Framework for Cutting the Pancreatic Cancer Fuel Supply
Anne Le, N.V. Rajeshkumar, Anirban Maitra, Chi Van Dang · 2012 · Clinical Cancer Research
Pharmacological regulators of autophagy and their link with modulators of lupus disease
Frédéric Gros, Sylviane Muller · 2014 · British Journal of Pharmacology
Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation
Roybel R. Ramiscal, Ian A. Parish, Robert S. Lee, Jeffrey J. Babon, Julianna Blagih, Alvin Pratama, Jaime L. Martin, Naomi Hawley, Jean Y. Cappello, Pablo F. Cañete et al. · 2015 · eLife
Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing
Xin Gu, Yan Yan, Scott J. Novick, Amanda Kovach, Devrishi Goswami, Jiyuan Ke, Michelle H. Tan, Lili Wang, Xiaodan Li, Parker W. de Waal et al. · 2017 · Journal of Biological Chemistry
Methionine restriction alleviates high-fat diet-induced obesity: Involvement of diurnal metabolism of lipids and bile acids
Luanfeng Wang, Bo Ren, Qian Zhang, Chuanqi Chu, Zhenting Zhao, Jianbin Wu, Weiyang Zhao, Zhigang Liu, Xuebo Liu · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
TAp73 is a marker of glutamine addiction in medulloblastoma
Maria Victoria Niklison-Chirou, Ida Erngren, Mikael K.R. Engskog, Jakob Haglöf, Daniel J. Picard, Marc Remke, Phelim Hugh Redmond McPolin, Matthew P. Selby, Daniel Williamson, Steven C. Clifford et al. · 2017 · Genes & Development
Metformin and its therapeutic applications in autoimmune inflammatory rheumatic disease
JW Kim, Jung‐Yoon Choe, Sung‐Hwan Park · 2021 · The Korean Journal of Internal Medicine
Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system
Ieva Gailite, Birgit L. Aerne, Nicolas Tapon · 2015 · Proceedings of the National Academy of Sciences
A Disruption Mechanism of the Molecular Clock in a MPTP Mouse Model of Parkinson’s Disease
Akane Hayashi, Naoya Matsunaga, Hiroyuki Okazaki, Keisuke Kakimoto, Yoshinori Kimura, Hiroki Azuma, Eriko Ikeda, Takeshi Shiba, Mayumi Yamato, Ken‐ichi Yamada et al. · 2013 · NeuroMolecular Medicine
Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC–ERK1/2–mTOR signaling pathway
Yuxiang Wang, Liyin Zhu, Satu Kuokkanen, Jeffrey W. Pollard · 2015 · Proceedings of the National Academy of Sciences
Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases
Helena Anna Malm, Inês G. Mollet, Christine Berggreen, Marju Orho‐Melander, Jonathan L.S. Esguerra, Olga Göransson, Lena Eliasson · 2016 · Molecular and Cellular Endocrinology
Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export
José Manuel Rodríguez-Vargas, María Isabel Rodríguez, Jara Majuelos‐Melguizo, Ángel García-Díaz, Ariannys González-Flores, Abelardo López‐Rivas, László Virág, Giuditta Illuzzi, Valérie Schreiber, Françoise Dantzer et al. · 2016 · Cell Death and Differentiation
Berberine modulates amyloid-β peptide generation by activating AMP-activated protein kinase
Haijing Zhang, Chunhui Zhao, Guoqiong Cao, Limin Guo, Shuai Zhang, Yuexia Liang, Chunxia Qin, Ping Su, Hang Li, Wensheng Zhang · 2017 · Neuropharmacology
The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation
Jun Hwan Kim, Dongyeob Seo, Sun‐Jick Kim, Dong Wook Choi, Jin Seok Park, Jihoon Ha, Jung‐Won Choi, Ji-Hyung Lee, Su Myung Jung, Kyoung‐Wan Seo et al. · 2018 · EMBO Reports
AMP-activated kinase is a regulator of fibroblast growth factor 23 production
Philipp Glosse, Martina Feger, Kerim Mutig, Hong Chen, Frank Hirche, Ahmed Abdallah Hasan, Mohamed M. S. Gaballa, Berthold Hocher, Florian J.W. Lang, Michael Föller · 2018 · Kidney International
Role of Protein Kinases in Hedgehog Pathway Control and Implications for Cancer Therapy
Valentina Montagnani, Barbara A. Stecca · 2019 · Cancers
Function and Transcriptional Regulation of Bovine TORC2 Gene in Adipocytes: Roles of C/EBPγ, XBP1, INSM1 and ZNF263
Rajwali Khan, Sayed Haidar Abbas Raza, Zainaguli Junjvlieke, Wang Xiaoyu, Matthew Garcia, Ibrahim Elsaeid Elnour, Wang Hongbao, Zan Linsen · 2019 · International Journal of Molecular Sciences
The Protective Effects of Melatonin Against LPS-Induced Septic Myocardial Injury: A Potential Role of AMPK-Mediated Autophagy
Shouyin Di, Zheng Wang, Wei Hu, Xiaolong Yan, Zhiqiang Ma, Xiaofei Li, Weimiao Li, Jianyuan Gao · 2020 · Frontiers in Endocrinology