Emerging regulation and functions of autophagy

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Kim, J., Kundu, M., Viollet, B., & Guan, K.-L. (2011) · Nature Cell Biology · doi:10.1038/ncb2152 · Cited by 7,227

Autophagy in the Pathogenesis of Disease

Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069

Autophagy fights disease through cellular self-digestion

Mizushima, N., Levine, B., Cuervo, A. M., & Klionsky, D. J. (2008) · Nature · doi:10.1038/nature06639 · Cited by 6,452

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200809125 · Cited by 4,026

Autophagy regulates lipid metabolism

Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975

Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation

Lunt, S. Y., & Vander Heiden, M. G. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154237 · Cited by 3,057

The Role of Atg Proteins in Autophagosome Formation

Mizushima, N., Yoshimori, T., & Ohsumi, Y. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154005 · Cited by 2,978

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R., et al. (2011) · Science · doi:10.1126/science.1196371 · Cited by 2,600

Eaten alive: a history of macroautophagy

Yang, Z., & Klionsky, D. J. (2010) · Nature Cell Biology · doi:10.1038/ncb0910-814 · Cited by 2,155

Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy

Zou, W., Hao, J., Wu, J., Cai, X., Hu, B. Q., Wang, Z., & Zheng, Y. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01166-y · Cited by 33

Coat protein of Chinese wheat mosaic virus upregulates and interacts with cytosolic glyceraldehyde‐3‐phosphate dehydrogenase, a negative regulator of plant autophagy, to promote virus infection

Niu, E., Ye, C., Zhao, W., Kondō, H., Wu, Y., Chen, J., Andika, I. B., & Sun, L. (2022) · Journal of Integrative Plant Biology · doi:10.1111/jipb.13313 · Cited by 33

Extracellular Vesicles from BMSCs Prevent Glucocorticoid-Induced BMECs Injury by Regulating Autophagy via the PI3K/Akt/mTOR Pathway

Ma, J., Shen, M., Yue, D., Wang, W., Gao, F., & Wang, B. (2022) · Cells · doi:10.3390/cells11132104 · Cited by 33

TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection

Wang, J., Qin, X., Huang, Y., Zhang, Q., Pei, J., Wáng, Y., Goren, I., Ma, S., Song, Z., Liu, Y., et al. (2022) · Autophagy · doi:10.1080/15548627.2022.2162706 · Cited by 34

Myocardial injury: where inflammation and autophagy meet

Liu, C., Liu, Y., Chen, H., Yang, X., Lu, C., Wang, L., & Lu, J. (2023) · Burns & Trauma · doi:10.1093/burnst/tkac062 · Cited by 33

Human CLEC16A regulates autophagy through modulating mTOR activity

Tam, R. C. Y., Li, M., Gao, Y., Pang, Y. T., Yan, S., Ge, W., Lau, C. S., & Chan, V. S. F. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.02.017 · Cited by 32

Autophagy orchestrates the crosstalk between cells and organs

Piletič, K., Alsaleh, G., & Simon, A. K. (2023) · EMBO Reports · doi:10.15252/embr.202357289 · Cited by 31

Mechanisms and therapeutic implications of selective autophagy in nonalcoholic fatty liver disease

Jin, S., Li, Y., Xia, T., Liu, Y., Zhang, S., Hu, H., Chang, Q., & Yan, M. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.01.027 · Cited by 35

Investigating autophagy and intricate cellular mechanisms in hepatocellular carcinoma: Emphasis on cell death mechanism crosstalk

Wang, G., Jiang, X., Torabian, P., & Yang, Z. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216744 · Cited by 33

The autophagy–lysosomal system in subarachnoid haemorrhage

Wu, H., Niu, H., Wu, C., Li, Y. H., Wang, K., Zhang, J., Wang, Y., & Yang, S. (2016) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12855 · Cited by 32

Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa

Vent-Schmidt, R. Y. J., Wen, R. H., Zong, Z., Chiu, C. N., Tam, B. M., May, C. G., & Moritz, O. L. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1647-16.2016 · Cited by 36

The functional significance of 14-3-3 proteins in cancer: focus on lung cancer

Khorrami, A., Bagheri, M. S., Tavallaei, M., & Gharechahi, J. (2017) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2017-0032 · Cited by 32

The role of host autophagy machinery in controllingToxoplasmainfection

Besteiro, S. (2018) · Virulence · doi:10.1080/21505594.2018.1518102 · Cited by 33

Huganpian, a traditional chinese medicine, inhibits liver cancer growth in vitro and in vivo by inducing autophagy and cell cycle arrest

Gao, X. J., Wang, Y., Li, Y., Wang, Y., Yan, M., Sun, H., Chen, S., & Pan, X. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109469 · Cited by 32

Pharmacological Tools to Modulate Autophagy in Neurodegenerative Diseases

Suresh, S., Chakravorty, A., Giridharan, M., Garimella, L., & Manjithaya, R. R. (2020) · Journal of Molecular Biology · doi:10.1016/j.jmb.2020.02.023 · Cited by 34

Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling

Xu, Q., Fan, Y., Loor, J. J., Liang, Y., Sun, X., Jia, H., Zhao, C., & Xu, C. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.601716 · Cited by 32

Selective autophagy: the rise of the zebrafish model

Pant, D. C., & Nazarko, T. Y. (2020) · Autophagy · doi:10.1080/15548627.2020.1853382 · Cited by 32

A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy

Lu, G. X., Wang, L., Zhou, J., Liu, W., & Shen, H. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.01.005 · Cited by 34

The Role of Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin

Chen, Y.-Y., Chen, C.-H., Lin, W.-C., Tung, C.-W., Chen, Y., Yang, S., Huang, B., & Chen, R.-J. (2021) · Molecules · doi:10.3390/molecules26164954 · Cited by 32

FGF2 Is Protective Towards Cisplatin-Induced KGN Cell Toxicity by Promoting FTO Expression and Autophagy

Wang, R., Wang, L., Wang, L., Cui, Z., Cheng, F., Wang, W., & Yang, X. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.890623 · Cited by 32

Autophagic regulation in steroid hormone-responsive systems

Park, J., Shin, H., Song, H., & Lim, H. J. (2016) · Steroids · doi:10.1016/j.steroids.2016.09.011 · Cited by 32

Ergosterol peroxide suppresses porcine deltacoronavirus (PDCoV)-induced autophagy to inhibit virus replication via p38 signaling pathway

Duan, C., Liu, Y., Hao, Z., & Wang, J. (2021) · Veterinary Microbiology · doi:10.1016/j.vetmic.2021.109068 · Cited by 31

Regulation of Paneth Cell Function by RNA-Binding Proteins and Noncoding RNAs

Chung, H. K., Xiao, L., Jaladanki, K. C., & Wang, J. (2021) · Cells · doi:10.3390/cells10082107 · Cited by 32

The relationship between autophagy and PD-L1 and their role in antitumor therapy

Cui, Y., Shi, J., Cui, Y., Zhu, Z., & Zhu, W. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1093558 · Cited by 32

Retinal Pigment Epithelium Under Oxidative Stress: Chaperoning Autophagy and Beyond

Markitantova, Y. V., & Simirskii, V. N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031193 · Cited by 34

Macroautophagic cargo sequestration assays

Seglen, P. O., Luhr, M., Mills, I. G., Sætre, F., Szalai, P., & Engedal, N. (2015) · Methods · doi:10.1016/j.ymeth.2014.12.021 · Cited by 31

Multiple roles of RARRES1 in prostate cancer: Autophagy induction and angiogenesis inhibition

Roy, A., Ramalinga, M., Kim, O. J., Chijioke, J., Lynch, S., Byers, S. W., & Kumar, D. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180344 · Cited by 31

Apurinic endonuclease 1 promotes the cisplatin resistance of lung cancer cells by inducing Parkin‑mediated mitophagy

Li, Z., Wang, Y., Wu, L., Dong, Y., Zhang, J., Chen, F., Xie, W., Huang, J., & Lü, N. (2019) · Oncology Reports · doi:10.3892/or.2019.7345 · Cited by 30

Towards a better understanding of the neuro-developmental role of autophagy in sickness and in health

Zapata‐Muñoz, J., Villarejo‐Zori, B., Largo‐Barrientos, P., & Boya, P. (2021) · Cell Stress · doi:10.15698/cst2021.07.253 · Cited by 33

Capsid protein from red-spotted grouper nervous necrosis virus induces incomplete autophagy by inactivating the HSP90ab1-AKT-MTOR pathway

Zhang, W., 中山大学海洋科学学院, 广. 广., Jia, P., Lu, X.-B., Chen, X., Weng, J., Jia, K., Yi, M., 南方海洋科学与工程广东省实验室(珠海), 广. 珠., 广东省海洋资源与近岸工程重点实验室, 广. 广., et al. (2021) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2021.249 · Cited by 31

TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2

Yang, C., Liu, J., Tong, B. C., Wang, Z., Zhu, Z., Su, C.-F., Sreenivasmurthy, S. G., Wu, J.-X., Iyaswamy, A., Krishnamoorthi, S., et al. (2021) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00711-7 · Cited by 32

Drug discovery by targeting the protein–protein interactions involved in autophagy

Xiang, H., Zhou, M., Li, Y., Zhou, L., & Wang, R. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2023.07.016 · Cited by 31

The Role of Autophagy as a Mechanism of Toxicity Induced by Multi-Walled Carbon Nanotubes in Human Lung Cells

Tsukahara, T., Matsuda, Y., & Haniu, H. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms16010040 · Cited by 31

Preserving mitochondrial homeostasis protects against drug-induced liver injury via inducing OPTN (optineurin)-dependent Mitophagy

Wang, J., Qiu, Y., Yang, L., Wang, J., He, J., Tang, C., Yang, Z., Hong, W., Yang, B., He, Q., et al. (2024) · Autophagy · doi:10.1080/15548627.2024.2384348 · Cited by 30

Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation

Bettoun, A., Joffre, C., Zago, G., Surdez, D., Vallerand, D., Gündoğdu, R., Sharif, A. A. D., Gómez-Ferrer, M., Cascone, I., Meunier, B., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.9875 · Cited by 31

The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress

Mans, L., Cano, L. Q., van Pelt, J., Giardoglou, P., Keune, W., & Haramis, A.-P. G. (2017) · Scientific Reports · doi:10.1038/s41598-017-07116-9 · Cited by 27

Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS

Shang, Y., Wang, Q., Li, J., Liu, H., Zhao, Q., Huang, X., Dong, H., Chen, W., Gui, R., & Nie, X. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.522708 · Cited by 29

The Valsa Mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple

Che, R., Liu, C., Wang, Q., Tu, W., Wang, P., Li, C., Gong, X., Mao, K., Feng, H., Huang, L., et al. (2022) · Autophagy · doi:10.1080/15548627.2022.2153573 · Cited by 30

Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity

Zhou, S., Zhang, Y., Zhou, Z., Jin, H., Hu, C., He, Z., Yu, Z., Ko, K., Yang, T., Zhang, X., et al. (2015) · Drug Design Development and Therapy · doi:10.2147/dddt.s77071 · Cited by 30

Autophagy and amino acid metabolism in the brain: implications for epilepsy

Bejarano, E., & Rodríguez‐Navarro, J. A. (2014) · Amino Acids · doi:10.1007/s00726-014-1822-z · Cited by 31

Why should cell biologists study microbial pathogens?

Welch, M. D. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-03-0144 · Cited by 32

Impaired Autophagy in Motor Neurons: A Final Common Mechanism of Injury and Death

Porras, M. A. G., Sieck, G. C., & Mantilla, C. B. (2018) · Physiology · doi:10.1152/physiol.00008.2018 · Cited by 31

DRAM1 regulates the migration and invasion of hepatoblastoma cells via autophagy-EMT pathway

Chen, C., Liang, Q., Chen, H.-K., Wu, P.-F., Feng, Z.-Y., Ma, X.-M., Wu, H.-R., & Zhou, G.-Q. (2018) · Oncology Letters · doi:10.3892/ol.2018.8937 · Cited by 34

Gemcitabine promotes autophagy and lysosomal function through ERK- and TFEB-dependent mechanisms

Marchand, B., Poulin, M.-A., Lawson, C., Tai, L., Jean, S., & Boucher, M. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01342-z · Cited by 32

Micro(nano)-plastics exposure induced programmed cell death and corresponding influence factors

Wu, Q., Cao, J., Liu, X., Zhu, X., Huang, C., Wang, X., & Song, Y. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.171230 · Cited by 29

Metalloptosis: metal ions-induced programmed cell death based on nanomaterials for cancer therapy

Wang, S., Ma, R., Mei, Z., & Hou, Y. (2024) · MedMat. · doi:10.1097/mm9.0000000000000004 · Cited by 30

Autophagy during ageing – from Dr Jekyll to Mr Hyde

Wilhelm, T., & Richly, H. (2018) · FEBS Journal · doi:10.1111/febs.14453 · Cited by 27

Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins

Wang, T., Niu, Y., Liu, S., Yuan, H., Liu, X., & Fu, L. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.07.023 · Cited by 29

Crosstalk between Autophagy and Nanomaterials: Internalization, Activation, Termination

Wei, F., & Duan, Y. (2018) · Advanced Biosystems · doi:10.1002/adbi.201800259 · Cited by 29

Therapeutic potential of endothelial progenitor cells in a rat model of epilepsy: Role of autophagy

Ali, S. O., Shahin, N. N., Safar, M. M., & Rizk, S. M. (2019) · Journal of Advanced Research · doi:10.1016/j.jare.2019.01.013 · Cited by 29

Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data

Guo, G., Wang, Y., Zhang, Y., Chen, X., Lu, J., Wang, H., Jiang, C., Qiu, H.-Q., & Xia, L. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i15.1840 · Cited by 30

The cellular responses of autophagy, apoptosis, and 5-methylcytosine level in zebrafish cells upon nutrient deprivation stress

Fan, X., Hou, T., Zhang, S., Guan, Y., Jia, J., & Wang, Z. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.124989 · Cited by 30

Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers

Trisolini, L., Laera, L., Favia, M., Muscella, A., Castegna, A., Pesce, V., Guerra, L., Grassi, A., Volpicella, M., & Pierri, C. L. (2020) · Biomolecules · doi:10.3390/biom11010038 · Cited by 29

Intersection between Redox Homeostasis and Autophagy: Valuable Insights into Neurodegeneration

Park, H., Kim, J., Shin, C., & Lee, S. (2021) · Antioxidants · doi:10.3390/antiox10050694 · Cited by 32

Autophagy is Required for the Maintenance of Liver Progenitor Cell Functionality

Cheng, Y., Wang, B., Zhou, H., Dang, S., Jin, M., Shi, Y., Li, H., Yang, Z., & Zhang, Y. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000430287 · Cited by 30

Molecular Targets in the Treatment of Cardiac Hypertrophy

Kühn, C., Hille, S. S., & Frey, N. (2015) · Springer eBooks · doi:10.1007/978-3-319-15961-4_18 · Cited by 29

Evolutionary trends and functional anatomy of the human expanded autophagy network

Till, A., Saito, R., Merkurjev, D., Liu, J., Syed, G. H., Kolnik, M., Siddiqui, A., Glas, M., Scheffler, B., Ideker, T., et al. (2015) · Autophagy · doi:10.1080/15548627.2015.1059558 · Cited by 31

Dynamin Regulates Autophagy by Modulating Lysosomal Function

Fang, X., Zhou, J., Liu, W., Duan, X., Gala, U., Sandoval, H., Jaiswal, M., & Tong, C. (2015) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2015.10.005 · Cited by 28

Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction

Berry, G. E., & Asokan, A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.687657 · Cited by 29

ROS Generated by Upconversion Nanoparticle-Mediated Photodynamic Therapy Induces Autophagy via PI3K/AKT/Mtor Signaling Pathway in M1 Peritoneal Macrophage

Han, X. B., Kou, J., Zheng, Y., Liu, Z., Jiang, Y., Gao, Z., Lin, C., & Yang, L. M. (2019) · Cellular Physiology and Biochemistry · doi:10.33594/000000093 · Cited by 29

Chondrocyte autophagy mechanism and therapeutic prospects in osteoarthritis

Li, L., Li, J., Li, J., Zhou, H., Zhu, X., Zhang, P., Huang, B., Zhao, W.-T., Zhao, X., & Chen, E. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1472613 · Cited by 29

Nerve Growth Factor Protects Against Alcohol-Induced Neurotoxicity in PC12 Cells via PI3K/Akt/mTOR Pathway

Liu, L., Sun, T., Xin, F., Cui, W., Guo, J., & Hu, J. (2016) · Alcohol and Alcoholism · doi:10.1093/alcalc/agw077 · Cited by 28

Beclin 1 and LC3 as predictive biomarkers for metastatic colorectal carcinoma

Zhao, H., Yang, M., & Zhao, B. (2017) · Oncotarget · doi:10.18632/oncotarget.19939 · Cited by 29

The primary cilium protein folliculin is part of the autophagy signaling pathway to regulate epithelial cell size in response to fluid flow

Zemirli, N., Boukhalfa, A., Dupont, N., Botti, J., Codogno, P., & Morel, É. (2019) · Cell Stress · doi:10.15698/cst2019.03.180 · Cited by 31

Zebrafish as a model to study autophagy and its role in skeletal development and disease

Moss, J. J., Hammond, C. L., & Lane, J. D. (2020) · Histochemistry and Cell Biology · doi:10.1007/s00418-020-01917-2 · Cited by 27

Autophagy in the HTR‐8/SVneo Cell Oxidative Stress Model Is Associated with the NLRP1 Inflammasome

Li, M., Sun, T., Wu, X., An, P., Wu, X., & Dang, H. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/2353504 · Cited by 28

FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon

Dong, S., Kong, N., Wang, C., Li, Y., Sun, D., Qin, W., Zhai, H., Zhai, X., Yang, X., Ye, C., et al. (2022) · Journal of Virology · doi:10.1128/jvi.00618-22 · Cited by 27

Inhibiting Cytoprotective Autophagy in Cancer Therapy: An Update on Pharmacological Small-Molecule Compounds

Zhang, L., Zhu, Y., Zhang, J., Zhang, L., & Chen, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.966012 · Cited by 29

Nrf2 Pathway and Autophagy Crosstalk: New Insights into Therapeutic Strategies for Ischemic Cerebral Vascular Diseases

Hu, Y. H., Luo, Y., & Zheng, Y. (2022) · Antioxidants · doi:10.3390/antiox11091747 · Cited by 29

Madecassoside ameliorates hepatic steatosis in high-fat diet-fed mice through AMPK/autophagy-mediated suppression of ER stress

Choi, S. W., Cho, W., Oh, H., El‐Aty, A. M. A., Hong, S. A., Hong, M. E., Jeong, J. H., & Jung, T. W. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115815 · Cited by 28

Kelch-Like Protein 2 Mediates Angiotensin II–With No Lysine 3 Signaling in the Regulation of Vascular Tonus

Zeniya, M., Morimoto, N., Takahashi, D., Mori, Y., Mori, T., Ando, F., Araki, Y., Yoshizaki, Y., Inoue, Y., Isobe, K., et al. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014070639 · Cited by 28

Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis

Pan, H., Zhong, X., & Lee, S. (2016) · BMC Biochemistry · doi:10.1186/s12858-016-0069-6 · Cited by 27

Uncovering the Rab5‐Independent Autophagic Trafficking of Influenza A Virus by Quantum‐Dot‐Based Single‐Virus Tracking

Wu, Q., Liu, S., Chen, G., Zhang, W., Sun, E., Xiao, G., Zhang, Z., & Pang, D. (2018) · Small · doi:10.1002/smll.201702841 · Cited by 27

Oleate disrupts cAMP signaling, contributing to potent stimulation of pancreatic β-cell autophagy

Chu, K. Y., O’Reilly, L., Mellet, N. A., Meikle, P. J., Bartley, C., & Biden, T. J. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.004833 · Cited by 29

Evaluating expression of autophagy-related genes in oriental river prawn Macrobrachium nipponense as potential biomarkers for hypoxia exposure

Sun, S., Wu, Y., Fu, H., Yang, M., Ge, X., Zhu, J. X., Xuan, F., & Wu, X. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2018.12.079 · Cited by 27

Characterization of the role of autophagy in retinal ganglion cell survival over time using a rat model of chronic ocular hypertension

Lee, S. H., Shim, K. S., Kim, C. Y., & Park, T. K. (2021) · Scientific Reports · doi:10.1038/s41598-021-85181-x · Cited by 27

Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress

Tiwari, S., Begum, S., Moreau, F., Gorman, H., & Chadee, K. (2021) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00221.2021 · Cited by 27

LAPped in Proof: LC3‐Associated Phagocytosis and the Arms Race Against Bacterial Pathogens

Grijmans, B. J. M., van der Kooij, S. B., Varela, M., & Meijer, A. H. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.809121 · Cited by 24

Exercise, Mitohormesis, and Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c)

Yoon, T. K., Lee, C. H., Kwon, O., & Kim, M. (2022) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2022.0092 · Cited by 28

Autophagy: A Potential Therapeutic Target to Tackle Drug Resistance in Multiple Myeloma

Bashiri, H., & Tabatabaeian, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076019 · Cited by 30

Signalling Pathways Controlling Cellular Actin Organization

Steffen, A., Stradal, T. E. B., & Rottner, K. (2016) · Handbook of experimental pharmacology · doi:10.1007/164_2016_35 · Cited by 26

cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion

Hua, R., Han, S., Zhang, N., Dai, Q., Liu, T., & Li, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051380 · Cited by 27

DNA damage response and GATA4 signaling in cellular senescence and aging-related pathology

Xiong, H., Hua, F., Dong, Y., Lin, Y., Ying, J., Liu, J., Wang, X., Zhang, L., & Zhang, J. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.933015 · Cited by 25

Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus

Schipper, H., Alla, V., Meier, C., Nettelbeck, D. M., Herchenröder, O., & Pützer, B. M. (2014) · Oncotarget · doi:10.18632/oncotarget.1839 · Cited by 26

Antiosteoclastic bone resorption activity of osteoprotegerin via enhanced AKT/mTOR/ULK1‐mediated autophagic pathway

Zhao, H., Sun, Z., Ma, Y., Song, R., Yuan, Y., Bian, J., Gu, J., & Liu, Z. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.29205 · Cited by 26

Involvement of the Autophagy-ER Stress Axis in High Fat/Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease

Zhou, X., Fouda, S., Li, D., Zhang, K., & Ye, J. (2020) · Nutrients · doi:10.3390/nu12092626 · Cited by 29

Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal

Orhon, I., Rocchi, C., Villarejo‐Zori, B., Martinez, P. S., Baanstra, M., Brouwer, U., Boya, P., Coppes, R. P., & Reggiori, F. (2021) · Autophagy · doi:10.1080/15548627.2021.1924036 · Cited by 26

Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver

Huda, N., Khambu, B., Liu, G., Nakatsumi, H., Yan, S., Chen, X., Ma, M., Dong, Z., Nakayama, K. I., & Yin, X. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.04.003 · Cited by 27

Roles of Stress Response in Autophagy Processes and Aging-Related Diseases

Watanabe, Y., Taguchi, K., & Tanaka, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813804 · Cited by 29

Transcription factors and cognate signalling cascades in the regulation of autophagy

Chandra, V., Bhagyaraj, E., Parkesh, R., & Gupta, P. (2016) · Biological Reviews · doi:10.1111/brv.12177 · Cited by 26

Cell-autonomous stress responses in innate immunity

Moretti, J., & Blander, J. M. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.2mr0416-201r · Cited by 27

The Degradation Pathway of the Mitophagy Receptor Atg32 Is Re-Routed by a Posttranslational Modification

Levchenko, M., Lorenzi, I., & Dudek, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168518 · Cited by 26

Involvement of the cysteine protease BcAtg4 in development and virulence of Botrytis cinerea

Liu, N., Ren, W., Li, F., Chen, C., & Ma, Z. (2018) · Current Genetics · doi:10.1007/s00294-018-0882-0 · Cited by 26

17β-estradiol inhibits H2O2-induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy

Xiang, X., Huang, J., Song, S., Wang, Y., Zeng, Y., Wu, S., & Ruan, Y. (2020) · Biogerontology · doi:10.1007/s10522-020-09868-w · Cited by 26

Nitrogen balance and outcomes in critically ill patients: A systematic review and meta-analysis

Zhu, Y., Yao, Y., Xu, Y., & Huang, H. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.961207 · Cited by 30

Autophagy as the effector and player in DNA damage response of cells to genotoxicants

Zhang, S.-M., Shang, Z., & Zhou, P. (2015) · Toxicology Research · doi:10.1039/c5tx00043b · Cited by 23

Genome-wide identification, characterization, and expression analysis of tea plant autophagy-related genes (CsARGs) demonstrates that they play diverse roles during development and under abiotic stress

Wang, H., Ding, Z., Gou, M., Hu, J., Wang, Y., Wang, L., Wang, Y., Di, T., Zhang, X., Hao, X., et al. (2021) · BMC Genomics · doi:10.1186/s12864-021-07419-2 · Cited by 26

Simultaneous activation of mitophagy and autophagy by staurosporine protects against dopaminergic neuronal cell death

Ha, J., Kim, J., Kim, S.-E., & Son, J. H. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2013.12.064 · Cited by 26

Autophagy and Autophagic Flux in Tumor Cells

Dupont, N., Orhon, I., Bauvy, C., & Codogno, P. (2014) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-801329-8.00004-0 · Cited by 25

Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria

Zeidler, J. D., Fernandes-Siqueira, L. O., Carvalho, A. S., Lopes, E. C., Dias, M. H., Ketzer, L. A., Galina, A., & Poian, A. T. D. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.786582 · Cited by 24

1 Autophagy: New emerging functions and concepts

Boya, P., Reggiori, F., & Codogno, P. (2016)

Autophagy: machinery and regulation

Yin, Z., Pascual, C., & Klionsky, D. J. (2016) · Microbial Cell · doi:10.15698/mic2016.12.546 · Cited by 582

Autophagy in cells of the blood

Yousefi, S., & Simon, H. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2008.12.023 · Cited by 32

The nonautophagic functions of autophagy-related proteins

Shang, J.-N., Yu, C.-G., Li, R. Q., Xi, Y., Jian, Y. J., Xu, N., & Chen, S. (2023) · Autophagy · doi:10.1080/15548627.2023.2254664 · Cited by 30

Autophagy at the crossroads of metabolism and cellular defense

Begun, J., & Xavier, R. J. (2013) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328365d34d · Cited by 10