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Discovery and characterization of antimycobacterial nitro-containing compounds with distinct mechanisms of action and in vivo efficacy

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AaABI5 transcription factor mediates light and abscisic acid signaling to promote anti-malarial drug artemisinin biosynthesis in Artemisia annua

Li, Y., Yang, Y., Li, P., Sheng, M., Li, L., Ma, X., Du, Z., Tang, K., Hao, X., & Kai, G. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.127345 · Cited by 14

Bacterial Histidine Kinase and the Development of Its Inhibitors in the 21st Century

Ahsan, R., Kifayat, S., Pooniya, K. K., Kularia, S., Adimalla, B. S., Sanapalli, B. K. R., Sanapalli, V., & Sigalapalli, D. K. (2024) · Antibiotics · doi:10.3390/antibiotics13070576 · Cited by 15

Nitrate-nitrite fate and oxygen sensing in dormant Mycobacterium tuberculosis: A bioinorganic approach highlighting the importance of transition metals

Sousa, E. H. S., Carepo, M. S. P., & Moura, J. J. G. (2020) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2020.213476 · Cited by 14

AaCycTL Regulates Cuticle and Trichome Development in Arabidopsis and Artemisia annua L.

Dong, B., Wang, X., Jiang, R. J., Fang, S., Li, J., Li, Q., Lv, Z. Y., & Chen, W. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.808283 · Cited by 14

Artemisia afra and Artemisia annua Extracts Have Bactericidal Activity against Mycobacterium tuberculosis in Physiologically Relevant Carbon Sources and Hypoxia

Kiani, B. H., Alonso, M. N., Weathers, P. J., & Shell, S. S. (2023) · Pathogens · doi:10.3390/pathogens12020227 · Cited by 13

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

Yang, X., Yuan, T., Ma, R., Chacko, K., Smith, M. L., Deikus, G. Y., Sebra, R., Kasarskis, A., van Bakel, H., Franzblau, S. G., et al. (2019) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00099 · Cited by 14

Metalloprotein enabled redox signal transduction in microbes

Williams, M. T., Yee, E., Larson, G. W., Apiche, E. A., Damodaran, A. R., & Bhagi‐Damodaran, A. (2023) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2023.102331 · Cited by 13

TrichomeLess Regulator 3 is required for trichome initial and cuticle biosynthesis in Artemisia annua

Dong, B., Xu, Z., Wang, X., Li, J., Xiao, Y., Huang, D., Lv, Z., & Chen, W. (2024) · Molecular Horticulture · doi:10.1186/s43897-024-00085-4 · Cited by 12

Relevance and regulation of alternative splicing in plant secondary metabolism: current understanding and future directions

Xu, Z., Xiao, Y., Guo, J., Lv, Z., & Chen, W. (2024) · Horticulture Research · doi:10.1093/hr/uhae173 · Cited by 14

Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis

Harrison, G. A., Wang, E. R., Cho, K., Mreyoud, Y., Sarkar, S., Almqvist, F., Patti, G. J., & Stallings, C. L. (2024) · mBio · doi:10.1128/mbio.02968-23 · Cited by 14

Artemisinin Targets Transcription Factor PDR1 and Impairs Candida glabrata Mitochondrial Function

Zhu, P., Yue, C., Zeng, X., & Chen, X. (2022) · Antioxidants · doi:10.3390/antiox11101855 · Cited by 12

A spectroelectrochemical investigation of the heme‐based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor

Barreto, G. A., Carepo, M. S. P., Gondim, A. C. S., Guimarães, W. G., Lopes, L. G. D. F., Bernhardt, P. V., Paulo, T. D. F., Sousa, E. H. S., & Diógenes, I. C. N. (2019) · FEBS Journal · doi:10.1111/febs.14974 · Cited by 12

Exploiting Fluorescent Proteins to Understand Mycobacterium tuberculosis Biology

Giacalone, D., Huang, L., & Tan, S. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1460-0_17 · Cited by 9

DNA Aptamer Targets Mycobacterium tuberculosis DevR/DosR Response Regulator Function by Inhibiting Its Dimerization and DNA Binding Activity

Chauhan, P., Datta, I., Dhiman, A., Shankar, U., Kumar, A., Vashist, A., Sharma, T. K., & Tyagi, J. S. (2022) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.2c00414 · Cited by 11

AaWRKY6 contributes to artemisinin accumulation during growth in Artemisia annua

Wang, X., Sun, W., Fang, S., Dong, B., Li, J., Li, W., Li, W., & Chen, W. (2023) · Plant Science · doi:10.1016/j.plantsci.2023.111789 · Cited by 10

Repurposing of anti-malarial drugs for the treatment of tuberculosis: realistic strategy or fanciful dead end?

Hänscheid, T., Luyten, C. R. D. P., Hermans, S., & Grobusch, M. P. (2024) · Malaria Journal · doi:10.1186/s12936-024-04967-2 · Cited by 11

Inhibiting Mycobacterium tuberculosis DosRST Signaling by Targeting Response Regulator DNA Binding and Sensor Kinase Heme

Zheng, H., Williams, J. T., Aleiwi, B., Ellsworth, E. L., & Abramovitch, R. B. (2019) · ACS Chemical Biology · doi:10.1021/acschembio.8b00849 · Cited by 62

Inhibiting DosRST As a New Approach to Tuberculosis Therapy

Zheng, H., & Abramovitch, R. B. (2020) · Future Medicinal Chemistry · doi:10.4155/fmc-2019-0263 · Cited by 33

The Mycobacterium DosR regulon structure and diversity revealed by comparative genomic analysis

Chen, T., He, L., Deng, W., & Xie, J. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24302 · Cited by 48

Design, synthesis and in vitro evaluation of a series of endoperoxide hybrids designed to tackle latent tuberculosis

Amado, P. S. M. (2023) · Universidade do Algarve

The DosRST two-component system of Mycobacterium tuberculosis: Characterizing the activation mechanism of DosR response regulator as a potential target for novel antimycobacterial drugs

Marszalek, M. (2014) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)