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Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens

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The ORFIUS complex regulates ORC2 localization at replication origins

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Vitamin D receptor cistrome-transcriptome analyses establishes quantitatively distinct receptor genomic interactions in African American prostate cancer regulated by BAZ1APreprint

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Kat7 accelerates osteoarthritis disease progression through the TLR4/NF-κB signaling pathway

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HBO1/KAT7/MYST2 HAT complex regulates human adenovirus replicative cycle

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KAT7 serves as an oncogenic gene and regulates CCL3 expression via STAT1 signaling in osteosarcoma

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CARM1/PRMT4 facilitates XPF–ERCC1 heterodimer assembly and maintains nucleotide excision repair activity

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Pathophysiological significance of impaired KAT7-dependent histone H3K14 acetylation during zinc deficiency

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Zebrafish Kat7b can up-regulate Nek7 to promote the NLRP3 inflammasome signaling pathway inhibited by β-sitosterol

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Histone acetyltransferase HBO1 in cancer biology: Essential mechanisms and implications for targeted therapeutics

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DNA damage-induced transcription stress : a focus on RNA polymerase II

Steurer, B. (2019) · RePub (Erasmus University Rotterdam)

Enhanced transcription activity of histone acetyltransferase HBO1 after genotoxic stress

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The Role of the Nucleotide-Excision Repair (NER) Pathway in Soft Tissue Sarcomas: A Review and a Focus on Its Potential as a Therapeutic Target

(2023) · Cancer Studies and Therapeutics · doi:10.31038/cst.2023824

HBO1 promotes replication stress response through ATR-dependent phosphorylation of Ser50/53Preprint

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ATR-dependent phosphorylation of the histone acetyltransferase HBO1 suppresses chromatin binding and promotes replication stress responses

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UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4 DDB2 -Mediated Degradation To Regulate Cell Proliferation

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DDB2-dependent recruitment of HBO1 is essential for nucleotide excision repair

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Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair

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HP1β-dependent recruitment of UBF1 to irradiated chromatin occurs simultaneously with CPDs

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Chromatin remodeler CHD1 promotes XPC‐to‐TFIIH handover of nucleosomal UV lesions in nucleotide excision repair

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