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Aldara activates TLR7-independent immune defence
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Aldara vehicle cream contains isostearic acid, which can trigger low-grade innate immune activation, including IL-1 release.
“It has been reported that Aldara vehicle cream contains isostearic acid, which has been reported to trigger low-grade innate immune activation, including IL-1 release38,39.”
From Macrophage INSIG1 deficiency drives psoriasiform dermatitis via the SREBP2-STAT1 axis (2026) · cites this paper as [38]
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Macrophage INSIG1 deficiency drives psoriasiform dermatitis via the SREBP2-STAT1 axis
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Metadata
- Authors
- Walter, A., Schäfer, M., Cecconi, V., Matter, C., Urosevic-Maiwald, M., Belloni, B., Schönewolf, N., Dummer, R., Bloch, W., Werner, S., Beer, H.-D., Knuth, A., & van den Broek, M.
- Venue
- Nature Communications
- Published
- 2013-03-05
- Volume
- 4
- Issue
- 1
- ISSN
- 2041-1723
- Cited by
- 245
- References
- 2
- Language
- en
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