Tumor Necrosis Factor Superfamily in Innate Immunity and Inflammation

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

The International IBD Genetics Consortium (IIBDGC), Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., et al. (2012) · Nature · doi:10.1038/nature11582 · Cited by 4,722 · see citing works

The TNF and TNF Receptor Superfamilies

Locksley, R. M., Killeen, N., & Lenardo, M. J. (2001) · Cell · doi:10.1016/s0092-8674(01)00237-9 · Cited by 3,650 · see citing works

Innate or adaptive immunity? The example of natural killer cells

Vivier, E., Raulet, D. H., Moretta, A., Caligiuri, M. A., Zitvogel, L., Lanier, L. L., Yokoyama, W. M., & Ugolini, S. (2011) · Science · doi:10.1126/science.1198687 · Cited by 2,824 · see citing works

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

The International Multiple Sclerosis Genetics Consortium & The Wellcome Trust Case Control Consortium 2 (2011) · Nature · doi:10.1038/nature10251 · Cited by 2,697 · see citing works

Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

Hemmi, H., Kaisho, T., Takeuchi, O., Sato, S., Sanjo, H., Hoshino, K., Horiuchi, T., Tomizawa, H., Takeda, K., & Akira, S. (2002) · Nature Immunology · doi:10.1038/ni758 · Cited by 2,517 · see citing works

Innate lymphoid cells — a proposal for uniform nomenclature

Spits, H., Artis, D., Colonna, M., Diefenbach, A., Disanto, J. D., Eberl, G., Koyasu, S., Locksley, R., McKenzie, A., Mebius, R., et al. (2013) · Nature reviews. Immunology · doi:10.1038/nri3365 · Cited by 2,380 · see citing works

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

van der Fits, L., Mourits, S., Voerman, J. S. A., Kant, M., Boon, L., Laman, J. D., Cornelissen, F., Mus, A.-M. C., Florencia, E. F., Prens, E. P., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802999 · Cited by 2,202 · see citing works

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’Amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M. B., Latiano, A., et al. (2011) · Nature Genetics · doi:10.1038/ng.764 · Cited by 1,312 · see citing works

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

Nurieva, R. I., Chung, Y., Hwang, D., Yang, X. O., Kang, H. S., Ma, L., Wang, Y.-H., Watowich, S. S., Jetten, A. M., Tian, Q., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.05.009 · Cited by 1,205 · see citing works

Multiple common variants for celiac disease influencing immune gene expression

Dubois, P. C. A., Trynka, G., Franke, L., Hunt, K. A., Romanos, J., Curtotti, A., Zhernakova, A., Heap, G., Ádány, R., Aromaa, A. J., et al. (2010) · Nature Genetics · doi:10.1038/ng.543 · Cited by 1,026 · see citing works

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

Cai, Y., Shen, X., Ding, C., Qi, C., Li, K., Li, X., Jala, V. R., Zhang, H., Wang, T., Zheng, J., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.08.001 · Cited by 1,021 · see citing works

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, J. G., Stojanov, P., Lawrence, M. S., Auclair, D., Chapuy, B., Sougnez, C. L., Cruz‐Gordillo, P., Knoechel, B., Asmann, Y. W., Slager, S. L., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121343109 · Cited by 977 · see citing works

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells

Link, A., Vogt, T. K., Favre, S., Britschgi, M. R., Acha‐Orbea, H., Hinz, B., Cyster, J. G., & Luther, S. A. (2007) · Nature Immunology · doi:10.1038/ni1513 · Cited by 934 · see citing works

The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways

Dejardin, E., Droin, N. M., Delhase, M., Haas, E., Cao, Y., Makris, C., Li, Z., Karin, M., Ware, C. F., & Green, D. R. (2002) · Immunity · doi:10.1016/s1074-7613(02)00423-5 · Cited by 923 · see citing works

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

Fuchs, A. G., Vermi, W., Lee, J. S., Lonardi, S., Gilfillan, S., Newberry, R. D., Cella, M., & Colonna, M. (2013) · Immunity · doi:10.1016/j.immuni.2013.02.010 · Cited by 904 · see citing works

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

Watanabe, N., Gavrieli, M., Sedy, J. R., Yang, J., Fallarino, F., Loftin, S. K., Hurchla, M. A., Zimmerman, N., Sim, J., Zang, X., et al. (2003) · Nature Immunology · doi:10.1038/ni944 · Cited by 883 · see citing works

Expansion of a unique CD57 ⁺ NKG2C ^hi natural killer cell subset during acute human cytomegalovirus infection

Lopez-Vergès, S., Milush, J. M., Schwartz, B. S., Pando, M. J., Jarjoura, J., York, V. A., Houchins, J. P., Miller, S., Kang, S.-M., Norris, P. J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1110900108 · Cited by 822 · see citing works

Type I Interferons Keep Activated T Cells Alive

Marrack, P., Kappler, J. W., & Mitchell, T. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.3.521 · Cited by 763 · see citing works

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

Mauri, D. N., Ebner, R., Montgomery, R. I., Kochel, K. D., Cheung, T. C., Yu, G.-L., Ruben, S. M., Murphy, M., Eisenberg, R. J., Cohen, G. H., et al. (1998) · Immunity · doi:10.1016/s1074-7613(00)80455-0 · Cited by 757 · see citing works

The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation

Gordon, S. M., Chaix, J., Rupp, L. J., Wu, J., Madera, S., Sun, J. C.-Y., Lindsten, T., & Reiner, S. L. (2012) · Immunity · doi:10.1016/j.immuni.2011.11.016 · Cited by 734 · see citing works

T Follicular Helper Cells Express a Distinctive Transcriptional Profile, Reflecting Their Role as Non-Th1/Th2 Effector Cells That Provide Help for B Cells

Chtanova, T., Tangye, S. G., Newton, R., Frank, N., Hodge, M. R., Rolph, M. S., & Mackay, C. R. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.1.68 · Cited by 722 · see citing works

Developing Lymph Nodes Collect CD4 + CD3 − LTβ + Cells That Can Differentiate to APC, NK Cells, and Follicular Cells but Not T or B Cells

Mebius, R. E., Rennert, P. D., & Weissman, I. L. (1997) · Immunity · doi:10.1016/s1074-7613(00)80371-4 · Cited by 688 · see citing works

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

Cupedo, T., Crellin, N. K., Papazian, N., Rombouts, E. J. C., Weijer, K. C., Grogan, J. L., Fibbe, W. E., Cornelissen, J. J., & Spits, H. (2008) · Nature Immunology · doi:10.1038/ni.1668 · Cited by 678 · see citing works

Progressive loss of RORγt expression confers distinct functional fates to natural killer cell receptor-expressing RORγt+ innate lymphocytes

Vonarbourg, C., Mortha, A., Bui, V. L., Hernández, P. P., Kiss, E. A., Hoyler, T., Flach, M., Bengsch, B., Thimme, R., Hölscher, C., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.10.017 · Cited by 669 · see citing works

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

Šedý, J. R., Gavrieli, M., Potter, K. G., Hurchla, M. A., Lindsley, R. C., Hildner, K. M., Scheu, S., Pfeffer, K., Ware, C. F., Murphy, T. L., et al. (2004) · Nature Immunology · doi:10.1038/ni1144 · Cited by 633 · see citing works

Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

Foley, B. A., Cooley, S., Verneris, M. R., Pitt, M., Curtsinger, J., Luo, X., López‐Vergès, S., Lanier, L. L., Weisdorf, D. J., & Miller, J. S. (2011) · Blood · doi:10.1182/blood-2011-10-386995 · Cited by 629 · see citing works

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

Ribot, J. C., deBarros, A., Pang, D. J., Neves, J. F., Peperzak, V., Roberts, S. J., Girardi, M., Borst, J., Hayday, A. C., Pennington, D. J., et al. (2009) · Nature Immunology · doi:10.1038/ni.1717 · Cited by 628 · see citing works

B cell receptor signal strength determines B cell fate

Casola, S. S., Otipoby, K. L., Alimzhanov, M. B., Humme, S., Uyttersprot, N., Kutok, J. L., Carroll, M. C., & Rajewsky, K. (2004) · Nature Immunology · doi:10.1038/ni1036 · Cited by 561 · see citing works

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

Harly, C., Guillaume, Y., Nédellec, S., Peigné, C.-M., Mönkkönen, H., Mönkkönen, J., Li, J., Kuball, J. H. E., Adams, E. J., Netzer, S., et al. (2012) · Blood · doi:10.1182/blood-2012-05-430470 · Cited by 546 · see citing works

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

Raychaudhuri, S., Remmers, E. F., Lee, A. T., Hackett, R., Guiducci, C., Burtt, N. P., Gianniny, L., Korman, B. D., Padyukov, L., Kurreeman, F. A. S., et al. (2008) · Nature Genetics · doi:10.1038/ng.233 · Cited by 534 · see citing works

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

Pantelyushin, S., Haak, S., Ingold, B., Kulig, P., Heppner, F. L., Navarini, A. A., & Becher, B. (2012) · Journal of Clinical Investigation · doi:10.1172/jci61862 · Cited by 515 · see citing works

Lineage Relationship Analysis of RORγt + Innate Lymphoid Cells

Sawa, S., Cherrier, M., Lochner, M., Satoh‐Takayama, N., Fehling, H. J., Vives, F. L., Santo, J. P. D., & Eberl, G. (2010) · Science · doi:10.1126/science.1194597 · Cited by 502 · see citing works

Evolutionary struggles between NK cells and viruses

Lanier, L. L. (2008) · Nature reviews. Immunology · doi:10.1038/nri2276 · Cited by 452 · see citing works

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

Satpathy, A. T., Briseño, C. G., Lee, J. S., Ng, D., Manieri, N. A., Wumesh, K. C., Wu, X., Thomas, S. R., Lee, W.-L., Turkoz, M., et al. (2013) · Nature Immunology · doi:10.1038/ni.2679 · Cited by 451 · see citing works

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

Gascoyne, D. M., Long, E., Veiga‐Fernandes, H., de Boer, J., Williams, O., Seddon, B. P., Coles, M. C., Kioussis, D., & Brady, H. J. M. (2009) · Nature Immunology · doi:10.1038/ni.1787 · Cited by 446 · see citing works

NETWORK COMMUNICATIONS: Lymphotoxins, LIGHT, and TNF

Ware, C. F. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115719 · Cited by 441 · see citing works

Mature natural killer cell and lymphoid tissue–inducing cell development requires Id2-mediated suppression of E protein activity

Boos, M. D., Yokota, Y., Eberl, G., & Kee, B. L. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20061959 · Cited by 389 · see citing works

Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen

Foley, B. A., Cooley, S., Verneris, M. R., Curtsinger, J., Luo, X., Waller, E. K., Anasetti, C., Weisdorf, D. J., & Miller, J. S. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1201964 · Cited by 369 · see citing works

CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

Cai, G., Anumanthan, A., Brown, J. A., Greenfield, E. A., Zhu, B., & Freeman, G. J. (2008) · Nature Immunology · doi:10.1038/ni1554 · Cited by 346 · see citing works

Dual nature of the adaptive immune system in lampreys

Guo, P., Hirano, M., Herrin, B. R., Li, J., Yu, C., Sadlonova, A., & Cooper, M. D. (2009) · Nature · doi:10.1038/nature08068 · Cited by 336 · see citing works

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Kamizono, S., Duncan, G. S., Seidel, M. G., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20092176 · Cited by 334 · see citing works

Intrinsic Lymphotoxin-β Receptor Requirement for Homeostasis of Lymphoid Tissue Dendritic Cells

Kabashima, K., Banks, T. A., Ansel, K. M., Lu, T. T., Ware, C. F., & Cyster, J. G. (2005) · Immunity · doi:10.1016/j.immuni.2005.02.007 · Cited by 327 · see citing works

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

van de Pavert, S. A., Olivier, B. J., Goverse, G., Vondenhoff, M. F. R., Greuter, M., Beke, P., Kusser, K. L., Höpken, U. E., Lipp, M., Niederreither, K., et al. (2009) · Nature Immunology · doi:10.1038/ni.1789 · Cited by 311 · see citing works

Balancing co-stimulation and inhibition with BTLA and HVEM

MURPHY, K. M. M., Nelson, C. A., & Šedý, J. R. (2006) · Nature reviews. Immunology · doi:10.1038/nri1917 · Cited by 309 · see citing works

Mature Follicular Dendritic Cell Networks Depend on Expression of Lymphotoxin β Receptor by Radioresistant Stromal Cells and of Lymphotoxin β and Tumor Necrosis Factor by B Cells

Endres, R., Alimzhanov, M. B., Plitz, T., Fütterer, A., Kosco‐Vilbois, M. H., Nedospasov, S. A., Rajewsky, K., & Pfeffer, K. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.1.159 · Cited by 304 · see citing works

The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T‐cell activation

Cai, G., & Freeman, G. J. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00783.x · Cited by 301 · see citing works

Protein tyrosine phosphatase function: the substrate perspective

Tiganis, T., & Bennett, A. M. (2007) · Biochemical Journal · doi:10.1042/bj20061548 · Cited by 299 · see citing works

High Numbers of Tumor-Infiltrating Programmed Cell Death 1–Positive Regulatory Lymphocytes Are Associated With Improved Overall Survival in Follicular Lymphoma

Carreras, J., López‐Guillermo, A., Roncador, G., Villamor, N., Colomo, L., Martı́nez, A., Hamoudi, R., Howat, W., Montserrat, E., & Campo, E. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.18.0513 · Cited by 296 · see citing works

IL ‐17‐producing γδ T cells and innate lymphoid cells

Sutton, C. E., Mielke, L. A., & Mills, K. H. G. (2012) · European Journal of Immunology · doi:10.1002/eji.201242569 · Cited by 275 · see citing works

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

Watchmaker, P. B., Lahl, K., Lee, M., Baumjohann, D., Morton, J. M., Kim, S. J., Zeng, R., Dent, A. L., Ansel, K. M., Diamond, B., et al. (2013) · Nature Immunology · doi:10.1038/ni.2768 · Cited by 267 · see citing works

Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence

Junt, T., Scandella, E., & Ludewig, B. (2008) · Nature reviews. Immunology · doi:10.1038/nri2414 · Cited by 264 · see citing works

Nonredundant Function of Soluble LTα 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis

Kruglov, A., Grivennikov, S. I., Kuprash, D. V., Winsauer, C., Prepens, S., Seleznik, G. M., Eberl, G., Littman, D. R., Heikenwälder, M. F., Tumanov, A. V., et al. (2013) · Science · doi:10.1126/science.1243364 · Cited by 262 · see citing works

Aldara activates TLR7-independent immune defence

Walter, A., Schäfer, M., Cecconi, V., Matter, C., Urosevic‐Maiwald, M., Belloni, B., Schönewolf, N., Dummer, R., Bloch, W., Werner, S., et al. (2013) · Nature Communications · doi:10.1038/ncomms2566 · Cited by 259 · see citing works

Different Cytokines Induce Surface Lymphotoxin-αβ on IL-7 Receptor-α Cells that Differentially Engender Lymph Nodes and Peyer's Patches

Yoshida, H., Naito, A., Inoue, J., Satoh, M., Santee, S. M., Ware, C. F., Togawa, A., Nishikawa, S., & Nishikawa, S. (2002) · Immunity · doi:10.1016/s1074-7613(02)00479-x · Cited by 250 · see citing works

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

Honke, N., Shaabani, N., Cadeddu, G., Sorg, U. R., Zhang, D., Trilling, M., Klingel, K., Sauter, M., Kandolf, R., Gailus, N., et al. (2011) · Nature Immunology · doi:10.1038/ni.2169 · Cited by 234 · see citing works

CD4+CD3− Accessory Cells Costimulate Primed CD4 T Cells through OX40 and CD30 at Sites Where T Cells Collaborate with B Cells

Kim, M., Gaspal, F., Wiggett, H. E., McConnell, F. M., Gulbranson‐Judge, A., Raykundalia, C., Walker, L. S. K., Goodall, M. D., & Lane, P. J. L. (2003) · Immunity · doi:10.1016/s1074-7613(03)00110-9 · Cited by 226 · see citing works

TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer

Walczak, H. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01066.x · Cited by 222 · see citing works

Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness

Wencker, M., Turchinovich, G., Barros, R. D. M., Deban, L., Jandke, A., Cope, A. P., & Hayday, A. (2013) · Nature Immunology · doi:10.1038/ni.2773 · Cited by 221 · see citing works

Slow Down and Survive: Enigmatic Immunoregulation by BTLA and HVEM

Murphy, T. L., & MURPHY, K. M. M. (2010) · Annual Review of Immunology · doi:10.1146/annurev-immunol-030409-101202 · Cited by 221 · see citing works

Ectopic Lymphoid-Organ Development Occurs through Interleukin 7-Mediated Enhanced Survival of Lymphoid-Tissue-Inducer Cells

Meier, D., Bornmann, C., Chappaz, S., Schmutz, S., Otten, L., Ceredig, R. H., Acha‐Orbea, H., & Finke, D. (2007) · Immunity · doi:10.1016/j.immuni.2007.04.009 · Cited by 219 · see citing works

Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway

Cheung, T. C., Humphreys, I. R., Potter, K. G., Norris, P. S., Shumway, H. M., Tran, B. R., Patterson, G., Jean-Jacques, R., Yoon, M., Spear, P. G., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506172102 · Cited by 209 · see citing works

A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

Nolte, M. A., Beliën, J. A. M., Eestermans, I. L., Jansen, W., Unger, W. W. J., van Rooijen, N., Kraal, G., & Mebius, R. E. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021801 · Cited by 209 · see citing works

Nonreceptor Protein-Tyrosine Phosphatases in Immune Cell Signaling

Pao, L. I., Badour, K., Siminovitch, K., & Neel, B. G. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115647 · Cited by 200 · see citing works

Unconventional ligand activation of herpesvirus entry mediator signals cell survival

Cheung, T. C., Steinberg, M. W., Oborne, L. M., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902115106 · Cited by 192 · see citing works

Acquired TNFRSF14 Mutations in Follicular Lymphoma Are Associated with Worse Prognosis

Cheung, K. J., Johnson, N. A., Affleck, J. G., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-2460 · Cited by 186 · see citing works

Cutting Edge: A Novel Viral TNF Receptor Superfamily Member in Virulent Strains of Human Cytomegalovirus

Benedict, C. A., Butrovich, K. D., Lurain, N. S., et al. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.12.6967 · Cited by 181 · see citing works

Langerin neg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice

Wohn, C., Ober-Blöbaum, J. L., Haak, S., Pantelyushin, S., Cheong, C., Zahner, S. P., Onderwater, S., Kant, M., Weighardt, H., Holzmann, B., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307569110 · Cited by 180 · see citing works

Defining the nature of human γδ T cells: a biographical sketch of the highly empathetic

Kalyan, S., & Kabelitz, D. (2012) · Cellular and Molecular Immunology · doi:10.1038/cmi.2012.44 · Cited by 163 · see citing works

New Insights into the Cell Biology of the Marginal Zone of the Spleen

Kraal, G., & Mebius, R. E. (2006) · International review of cytology · doi:10.1016/s0074-7696(06)50005-1 · Cited by 159 · see citing works

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Swami, M. (2011) · Nature Medicine · doi:10.1038/nm.2482 · Cited by 158 · see citing works

B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity

Moseman, E. A., Iannacone, M., Bosurgi, L., Tonti, E., Chevrier, N., Tumanov, A. V., Fu, Y., Hacohen, N., & von Andrian, U. H. (2012) · Immunity · doi:10.1016/j.immuni.2012.01.013 · Cited by 155 · see citing works

Lymphotoxin Beta Receptor Signaling in Intestinal Epithelial Cells Orchestrates Innate Immune Responses against Mucosal Bacterial Infection

Wang, Y., Koroleva, E. P., Kruglov, A., Kuprash, D. V., Nedospasov, S. A., Fu, Y., & Tumanov, A. V. (2010) · Immunity · doi:10.1016/j.immuni.2010.02.011 · Cited by 154 · see citing works

LTβR Signaling Induces Cytokine Expression and Up-Regulates Lymphangiogenic Factors in Lymph Node Anlagen

Vondenhoff, M. F. R., Greuter, M., Goverse, G., Elewaut, D. S., Dewint, P., Ware, C. F., Hoorweg, K., Kraal, G., & Mebius, R. E. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0801165 · Cited by 153 · see citing works

CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

Peretz, Y., He, Z., Shi, Y., Yassine‐Diab, B., Goulet, J.-P., Bordi, R., Filali‐Mouhim, A., Loubert, J.-B., Far, M. E., Dupuy, F. P., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002840 · Cited by 148 · see citing works

Tumor Necrosis Factor Receptor Superfamily 14 Is Involved in Atherogenesis by Inducing Proinflammatory Cytokines and Matrix Metalloproteinases

Lee, W., Kim, S., Lee, Y. M., Lee, B.-B., Kwon, B., Song, H., Kwon, B. S., & Park, J.-E. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/hq1201.098945 · Cited by 148 · see citing works

Lymphotoxin-Mediated Regulation of γδ Cell Differentiation by αß T Cell Progenitors

Silva-Santos, B., Pennington, D. J., & Hayday, A. C. (2005) · Science · doi:10.1126/science.1103978 · Cited by 147 · see citing works

Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity

Bouteiller, P. P. L., Barakonyi, A., Giustiniani, J., Lenfant, F., Marie‐Cardine, A., Aguerre‐Girr, M., Rabot, M., Hilgert, I., Mami‐Chouaib, F., Tabiasco, J., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012681099 · Cited by 146 · see citing works

Origin and evolution of TNF and TNF receptor superfamilies

Wiens, G. D., & Glenney, G. W. (2011) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2011.03.031 · Cited by 145 · see citing works

Lymphotoxin-Mediated Crosstalk between B Cells and Splenic Stroma Promotes the Initial Type I Interferon Response to Cytomegalovirus

Schneider, K., Loewendorf, A. I., Trez, C. D., Fulton, J., Rhode, A., Shumway, H. M., Ha, S., Patterson, G., Pfeffer, K., Nedospasov, S. A., et al. (2008) · Cell Host & Microbe · doi:10.1016/j.chom.2007.12.008 · Cited by 144 · see citing works

Genetic analysis of protein tyrosine phosphatases

Vactor, D. V., O’Reilly, A. M., & Neel, B. G. (1998) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(98)80070-1 · Cited by 142 · see citing works

Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent TFH–B cell axis

Pangault, C., Amé-Thomas, P., Ruminy, P., Delphine Rossille, A., Caron, G., Baia, M., Vos, J. D., Roussel, M., Monvoisin, C., Lamy, T., et al. (2010) · Leukemia · doi:10.1038/leu.2010.223 · Cited by 142 · see citing works

Lymphotoxin-β Receptor Signaling through NF-κB2-RelB Pathway Reprograms Adipocyte Precursors as Lymph Node Stromal Cells

Bénézech, C., Mader, E., Desanti, G. E., Khan, M., Nakamura, K., White, A. J., Ware, C. F., Anderson, G., & Caamaño, J. (2012) · Immunity · doi:10.1016/j.immuni.2012.06.010 · Cited by 141 · see citing works

Lymphoid organ development and cell migration

Cyster, J. G. (2003) · Immunological Reviews · doi:10.1034/j.1600-065x.2003.00075.x · Cited by 139 · see citing works

A crucial role for HVEM and BTLA in preventing intestinal inflammation

Steinberg, M. W., Turovskaya, O., Shaikh, R. B., Kim, G., McCole, D. F., Pfeffer, K., MURPHY, K. M. M., Ware, C. F., & Kronenberg, M. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071160 · Cited by 137 · see citing works

Adaptive reconfiguration of the human NK‐cell compartment in response to cytomegalovirus: A different perspective of the host‐pathogen interaction

Muntasell, A., Vilches, C., Angulo, A., & López‐Botet, M. (2013) · European Journal of Immunology · doi:10.1002/eji.201243117 · Cited by 132 · see citing works

HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

Shui, J., Larangé, A., Kim, G., Vela, J. L., Zahner, S. P., Cheroutre, H., & Kronenberg, M. (2012) · Nature · doi:10.1038/nature11242 · Cited by 132 · see citing works

Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells

Heatley, S. L., Pietra, G., Lin, J., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.409672 · Cited by 128 · see citing works

Ube1L and Protein ISGylation Are Not Essential for Alpha/Beta Interferon Signaling

Kim, K. I., Yan, M., Malakhova, O. A., Luo, J.-K., Shen, M., Zou, W., de la Torre, J. C., & Zhang, D. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.26.2.472-479.2006 · Cited by 127 · see citing works

Controlling cytokine signaling by constitutive inhibitors

Rakesh, K., & Agrawal, D. K. (2005) · Biochemical Pharmacology · doi:10.1016/j.bcp.2005.04.042 · Cited by 122 · see citing works

Differential Effects of B and T Lymphocyte Attenuator and Programmed Death-1 on Acceptance of Partially versus Fully MHC-Mismatched Cardiac Allografts

Tao, R., Wang, L., Han, R., Wang, T., Ye, Q., Honjo, T., Murphy, T. L., MURPHY, K. M. M., & Hancock, W. W. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.9.5774 · Cited by 120 · see citing works

RelA and RelB Transcription Factors in Distinct Thymocyte Populations Control Lymphotoxin-Dependent Interleukin-17 Production in γδ T Cells

Powolny‐Budnicka, I., Riemann, M., Tänzer, S., Schmid, R. M., Hehlgans, T., & Weih, F. (2011) · Immunity · doi:10.1016/j.immuni.2011.02.019 · Cited by 119 · see citing works

B and T Lymphocyte Attenuator Regulates B Cell Receptor Signaling by Targeting Syk and BLNK

Vendel, A. C., Calemine-Fenaux, J., Izrael-Tomasevic, A., Chauhan, V., Arnott, D. P., & Eaton, D. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.3.1509 · Cited by 118 · see citing works

Expression of the lymphotoxin β receptor on follicular stromal cells in human lymphoid tissues

Murphy, M., Walter, B. N., Pike-Nobile, L., et al. (1998) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400374 · Cited by 117 · see citing works

A novel 80-kD cell surface structure identifies human circulating lymphocytes with natural killer activity.

Maiza, H., Leca, G., Mansur, I. G., et al. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.178.3.1121 · Cited by 115 · see citing works

Cutting Edge: Engagement of CD160 by its HLA-C Physiological Ligand Triggers a Unique Cytokine Profile Secretion in the Cytotoxic Peripheral Blood NK Cell Subset

Barakonyi, A., Rabot, M., Marie‐Cardine, A., Aguerre‐Girr, M., Polgár, B., Schiavon, V., Bensussan, A., & Bouteiller, P. P. L. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.9.5349 · Cited by 113 · see citing works

Specific Remodeling of Splenic Architecture by Cytomegalovirus

Benedict, C. A., Trez, C. D., Schneider, K., et al. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020016 · Cited by 111 · see citing works

High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosis

Launay, E., Pangault, C., Bertrand, P., et al. (2011) · Leukemia · doi:10.1038/leu.2011.266 · Cited by 111 · see citing works

The UL144 gene product of human cytomegalovirus activates NFκB via a TRAF6‐dependent mechanism

Poole, E. L., King, C. A., Sinclair, J. H., & Alcamı́, A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601287 · Cited by 108 · see citing works

Molecular signatures of T-cell inhibition in HIV-1 infection

Larsson, M., Shankar, E. M., Che, K. F., Saeidi, A., Ellegård, R., Barathan, M., Velu, V., & Kamarulzaman, A. (2013) · Retrovirology · doi:10.1186/1742-4690-10-31 · Cited by 108 · see citing works

Human Cytomegalovirus Glycoprotein UL141 Targets the TRAIL Death Receptors to Thwart Host Innate Antiviral Defenses

Smith, W., Tomašec, P., Aicheler, R., Loewendorf, A. I., Nemčovičová, I., Wang, E. C. Y., Stanton, R. J., Macauley, M., Norris, P. S., Willen, L., et al. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.02.003 · Cited by 108 · see citing works

TNF Superfamily Networks: bidirectional and interference pathways of the herpesvirus entry mediator (TNFSF14)

Ware, C. F., & Šedý, J. R. (2011) · Current Opinion in Immunology · doi:10.1016/j.coi.2011.08.008 · Cited by 105 · see citing works

The co-receptor BTLA negatively regulates human Vγ9Vδ2 T-cell proliferation: a potential way of immune escape for lymphoma cells

Gertner-Dardenne, J., Fauriat, C., Orlanducci, F., Thibult, M., Pastor, S., Fitzgibbon, J., Bouabdallah, R., Xerri, L., & Olive, D. (2013) · Blood · doi:10.1182/blood-2012-11-464685 · Cited by 100 · see citing works

CD160 Activation by Herpesvirus Entry Mediator Augments Inflammatory Cytokine Production and Cytolytic Function by NK Cells

Šedý, J. R., Bjordahl, R., Bekiaris, V., Macauley, M. G., Ware, B. C., Norris, P. S., Lurain, N. S., Benedict, C. A., & Ware, C. F. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300894 · Cited by 100 · see citing works

Shp1 regulates T cell homeostasis by limiting IL-4 signals

Johnson, D. J., Pao, L. I., Dhanji, S., Murakami, K., Ohashi, P. S., & Neel, B. G. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20122239 · Cited by 98 · see citing works

Clinical quantitation of immune signature in follicular lymphoma by RT-PCR–based gene expression profiling

Byers, R. J., Sakhinia, E., Joseph, P., et al. (2008) · Blood · doi:10.1182/blood-2007-10-115915 · Cited by 97 · see citing works

The Inhibitory Receptor BTLA Controls γδ T Cell Homeostasis and Inflammatory Responses

Bekiaris, V., Šedý, J. R., Macauley, M. G., Rhode-Kurnow, A., & Ware, C. F. (2013) · Immunity · doi:10.1016/j.immuni.2013.10.017 · Cited by 95 · see citing works

Murine CD160, Ig-Like Receptor on NK Cells and NKT Cells, Recognizes Classical and Nonclassical MHC Class I and Regulates NK Cell Activation

Maeda, M., Carpenito, C., Russell, R. C., Dasanjh, J., Veinotte, L. L., Ohta, H., Yamamura, T., Tan, R., & Takei, F. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.7.4426 · Cited by 92 · see citing works

High Expression of the Inhibitory Receptor BTLA in T-Follicular Helper Cells and in B-Cell Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia

M’Hidi, H., Thibult, M., Chetaille, B., Gondois‐Rey, F., Bouadallah, R., Nicollas, R., Olive, D., & Xerri, L. (2009) · American Journal of Clinical Pathology · doi:10.1309/ajcpphkgyyggl39c · Cited by 90 · see citing works

Cutting Edge: B and T Lymphocyte Attenuator and Programmed Death Receptor-1 Inhibitory Receptors Are Required for Termination of Acute Allergic Airway Inflammation

Deppong, C. M., Juehne, T. I., Hurchla, M. A., Friend, L. D., Shah, D. D., Rose, C. M., Bricker, T. L., Shornick, L. P., Crouch, E. C., Murphy, T. L., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.3909 · Cited by 89 · see citing works

CD160: A unique activating NK cell receptor

Bouteiller, P. P. L., Tabiasco, J., Polgár, B., Kozma, N., Giustiniani, J., Siewiera, J., Berrebi, A., Aguerre‐Girr, M., Bensussan, A., & Jabrane‐Ferrat, N. (2011) · Immunology Letters · doi:10.1016/j.imlet.2011.02.003 · Cited by 89 · see citing works

CXCR3 Binding Chemokine and TNFSF14 Over Expression in Bladder Urothelium of Patients With Ulcerative Interstitial Cystitis

Ogawa, T., Homma, T., Igawa, Y., et al. (2010) · The Journal of Urology · doi:10.1016/j.juro.2009.11.007 · Cited by 88 · see citing works

A Lymphotoxin-IFN-β Axis Essential for Lymphocyte Survival Revealed during Cytomegalovirus Infection

Banks, T. A., Rickert, S., Benedict, C. A., et al. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.11.7217 · Cited by 88 · see citing works

Association of Grb-2 and PI3K p85 with phosphotyrosile peptides derived from BTLA

Gavrieli, M., & Murphy, K. M. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.05.036 · Cited by 85 · see citing works

The Inhibitory HVEM-BTLA Pathway Counter Regulates Lymphotoxin β Receptor Signaling to Achieve Homeostasis of Dendritic Cells

Trez, C. D., Schneider, K., Potter, K. G., Droin, N. M., Fulton, J., Norris, P. S., Ha, S., Fu, Y., Murphy, T. L., MURPHY, K. M. M., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.1.238 · Cited by 82 · see citing works

γδ T Cell Homeostasis Is Controlled by IL-7 and IL-15 Together with Subset-Specific Factors

Baccalà, R., Witherden, D. A., González‐Quintial, R., Dummer, W., Surh, C. D., Havran, W. L., & Theofilopoulos, A. N. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.8.4606 · Cited by 80 · see citing works

Neonatal and Adult CD4+CD3− Cells Share Similar Gene Expression Profile, and Neonatal Cells Up-Regulate OX40 Ligand in Response to TL1A (TNFSF15)

Kim, M., Toellner, K., White, A. J., McConnell, F. M., Gaspal, F., Parnell, S. M., Jenkinson, E. J., Anderson, G., & Lane, P. J. L. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.5.3074 · Cited by 77 · see citing works

Cross-regulation between herpesviruses and the TNF superfamily members

Šedý, J. R., Spear, P. G., & Ware, C. F. (2008) · Nature reviews. Immunology · doi:10.1038/nri2434 · Cited by 74 · see citing works

Allosteric Regulation of the Ubiquitin:NIK and Ubiquitin:TRAF3 E3 Ligases by the Lymphotoxin-β Receptor

Sanjo, H., Zajonc, D. M., Braden, R. L., Norris, P. S., & Ware, C. F. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.105874 · Cited by 74 · see citing works

The Level of Hepatitis B Virus Replication Is Not Affected by Protein ISG15 Modification but Is Reduced by Inhibition of UBP43 (USP18) Expression

Kim, J.-H., Luo, J.-K., & Zhang, D. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.9.6467 · Cited by 74 · see citing works

Recurrent loss of heterozygosity in 1p36 associated with TNFRSF14 mutations in IRF4 translocation negative pediatric follicular lymphomas

Martín‐Guerrero, I., Salaverría, I., Burkhardt, B., et al. (2013) · Haematologica · doi:10.3324/haematol.2012.073916 · Cited by 73 · see citing works

BY55/CD160 acts as a co‐receptor in TCR signal transduction of a human circulating cytotoxic effector T lymphocyte subset lacking CD28 expression

Nikolova, M. H., Marie‐Cardine, A., Boumsell, L., & Bensussan, A. (2002) · International Immunology · doi:10.1093/intimm/14.5.445 · Cited by 71 · see citing works

B and T Lymphocyte Attenuator Is Highly Expressed on CMV-Specific T Cells during Infection and Regulates Their Function

Serriari, N., Gondois‐Rey, F., Guillaume, Y., Remmerswaal, E. B. M., Pastor, S., Messal, N., Truneh, A., Hirsch, I., van Lier, R. A. W., & Olive, D. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902487 · Cited by 68 · see citing works

Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis

White, A. J., Carragher, D. M., Parnell, S. M., Msaki, A., Perkins, N. D., Lane, P. J. L., Jenkinson, E. J., Anderson, G., & Caamaño, J. (2007) · Blood · doi:10.1182/blood-2007-01-070003 · Cited by 61 · see citing works

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells

Kobayashi, Y., Iwata, A., Suzuki, K., Suto, A., Kawashima, S., Saito, Y., Owada, T., Kobayashi, M., Watanabe, N., & Nakajima, H. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222093110 · Cited by 59 · see citing works

Differential and tumor-specific expression of CD160 in B-cell malignancies

Farren, T., Giustiniani, J., Liu, F., Tsitsikas, D. A., Macey, M. G., Cavenagh, J. D., Oakervee, H. E., Taussig, D. C., Newland, A. C., Calaminici, M., et al. (2011) · Blood · doi:10.1182/blood-2011-02-334326 · Cited by 56 · see citing works

Enhanced Plasma Levels of LIGHT in Unstable Angina

Scholz, H., Sandberg, W. J., Damås, J. K., Smith, C., Andreassen, A. K., Gullestad, L. L., Frøland, S. S., Yndestad, A., Aukrust, P., & Halvorsen, B. L. (2005) · Circulation · doi:10.1161/circulationaha.105.544676 · Cited by 55 · see citing works

B and T Lymphocyte Attenuator Tempers Early Infection Immunity

Sun, Y., Brown, N. K., Ruddy, M. J., Miller, M. L., Lee, Y., Wang, Y., Murphy, K. M., Pfeffer, K., Chen, L., Kaye, J., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0801866 · Cited by 51 · see citing works

High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases

Jung, H. W., La, S. J., Kim, J. Y., et al. (2003) · Experimental & Molecular Medicine · doi:10.1038/emm.2003.65 · Cited by 50 · see citing works

Association of BTLA gene polymorphisms with the risk of malignant breast cancer in Chinese women of Heilongjiang Province

Fu, Z., Li, D., Jiang, W., Wang, L., Zhang, J., Xu, F., Pang, D., & Li, D. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-009-0462-6 · Cited by 48 · see citing works

Rheumatoid Arthritis in Latin Americans Enriched for Amerindian Ancestry Is Associated With Loci in Chromosomes 1, 12, and 13, and the HLA Class II Region

Herráez, D. L., Martínez‐Bueno, M., Riba, L., Torre, I. G.-D. L., Sacnun, M. P., Goñi, M. A., Berbotto, G. A., Paira, S. O., Musuruana, J. L., Graf, C. E., et al. (2013) · Arthritis & Rheumatism · doi:10.1002/art.37923 · Cited by 47 · see citing works

Ligation of B and T Lymphocyte Attenuator Prevents the Genesis of Experimental Cerebral Malaria

Lepenies, B., Pfeffer, K., Hurchla, M. A., Murphy, T. L., MURPHY, K. M. M., Oetzel, J., Fleischer, B., & Jacobs, T. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.6.4093 · Cited by 46 · see citing works

Coinhibitory Molecules in Autoimmune Diseases

Watanabe, N., & Nakajima, H. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/269756 · Cited by 45 · see citing works

Skewed distribution of natural killer cells in psoriasis skin lesions

Batista, M. D., Ho, E. L., Kuebler, P., Milush, J. M., Lanier, L. L., Kallas, E. G., York, V. A., Chang, D., Liao, W. J., Unemori, P., et al. (2012) · Experimental Dermatology · doi:10.1111/exd.12060 · Cited by 45 · see citing works

B-Lymphocyte Dysfunction in Chronic HIV-1 Infection Does Not Prevent Cross-Clade Neutralization Breadth

Boliar, S., Murphy, M. K., Tran, T. C., et al. (2012) · Journal of Virology · doi:10.1128/jvi.00771-12 · Cited by 45 · see citing works

CD160-activating NK cell effector functions depend on the phosphatidylinositol 3-kinase recruitment

Rabot, M., Costa, H. E., Polgár, B., Marie‐Cardine, A., Aguerre‐Girr, M., Barakonyi, A., Valitutti, S., Bensussan, A., & Bouteiller, P. L. (2007) · International Immunology · doi:10.1093/intimm/dxm005 · Cited by 45 · see citing works

Th1‐ and Th2‐like subsets of innate lymphoid cells

Bernink, J. H., Mjösberg, J., & Spits, H. (2013) · Immunological Reviews · doi:10.1111/imr.12034 · Cited by 43 · see citing works

Elevated levels of IFNγ and LIGHT in the spinal cord of patients with sporadic amyotrophic lateral sclerosis

Aebischer, J., Moumen, A., Sazdovitch, V., Seilhean, D., Meininger, V., & Raoul, C. (2012) · European Journal of Neurology · doi:10.1111/j.1468-1331.2011.03623.x · Cited by 42 · see citing works

Association of a BTLA gene polymorphism with the risk of rheumatoid arthritis

Lin, S., Kuo, C., & Chan, C.-H. (2006) · Journal of Biomedical Science · doi:10.1007/s11373-006-9113-7 · Cited by 42 · see citing works

A Functional Polymorphism in B and T Lymphocyte Attenuator Is Associated with Susceptibility to Rheumatoid Arthritis

Oki, M., Watanabe, N., Owada, T., Oya, Y., Ikeda, K., Saito, Y., Matsumura, R., Seto, Y., Iwamoto, I., & Nakajima, H. (2011) · Clinical and Developmental Immunology · doi:10.1155/2011/305656 · Cited by 40 · see citing works

Molecular Basis for Herpesvirus Entry Mediator Recognition by the Human Immune Inhibitory Receptor CD160 and Its Relationship to the Cosignaling Molecules BTLA and LIGHT

Kojima, R., Kajikawa, M., Shiroishi, M., et al. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.09.018 · Cited by 40 · see citing works

Constitutive Expression and Costimulatory Function of LIGHT/TNFSF14 on Human Melanoma Cells and Melanoma-Derived Microvesicles

Mortarini, R., Scarito, A., Nonaka, D., Zanon, M., Bersani, I., Montaldi, E., Pennacchioli, E., Patuzzo, R., Santinami, M., & Anichini, A. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3239 · Cited by 39 · see citing works

B and T lymphocyte attenuator interacts with CD3ζ and inhibits tyrosine phosphorylation of TCRζ complex during T‐cell activation

Wu, T., Yu, Z., Zeng, C., et al. (2007) · Immunology and Cell Biology · doi:10.1038/sj.icb.7100087 · Cited by 36 · see citing works

Identification of a Novel CD160+CD4+ T-Lymphocyte Subset in the Skin: A Possible Role for CD160 in Skin Inflammation

Abecassis, S., Giustiniani, J., Meyer, N., et al. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700680 · Cited by 36 · see citing works

The tyrosine phosphatase SHP-1 dampens murine Th17 development.

Mauldin, I., Tung, K., & Lorenz, U. (2012) · Blood · doi:10.1182/blood-2011-09-377069 · Cited by 35 · see citing works

Elevated plasma levels and platelet‐associated expression of the pro‐thrombotic and pro‐inflammatory protein, T NFSF14 (LIGHT), in sickle cell disease

Garrido, V. T., Proença‐Ferreira, R., Dominical, V. M., Traina, F., Bezerra, M., de Mello, M. R. B., Colella, M. P., Araujo, A. S., Saad, S. T. O., Costa, F. F., et al. (2012) · British Journal of Haematology · doi:10.1111/j.1365-2141.2012.09218.x · Cited by 35 · see citing works

B and T Lymphocyte Attenuator Down-regulation by HIV-1 Depends on Type I Interferon and Contributes to T-Cell Hyperactivation

Zhang, Z., Xu, X., Lu, J., Zhang, S., Gu, L., Fu, J., Jin, L., Li, H., Zhao, M., Zhang, J., et al. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir165 · Cited by 35 · see citing works

CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice

Sun, X., Shibata, K., Yamada, H., Guo, Y. J., Muta, H., Podack, E. R., & Yoshikai, Y. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.18 · Cited by 33 · see citing works

Deletion of the activating NKG 2C receptor and a functional polymorphism in its ligand HLA ‐E in psoriasis susceptibility

Zeng, X., Chen, H., Gupta, R., et al. (2013) · Experimental Dermatology · doi:10.1111/exd.12233 · Cited by 33 · see citing works

LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8 + T cells

deLuca, L. S., Ng, D., Gao, Y., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1014188108 · Cited by 33 · see citing works

Characterization of Herpes Virus Entry Mediator as a Factor Linked to Obesity

Bassols, J., Moreno‐Navarrete, J. M., Ortega, F. J., et al. (2009) · Obesity · doi:10.1038/oby.2009.250 · Cited by 31 · see citing works

The role of inflammatory chemokines in lymphoid neoorganogenesis in breast cancer

Gantsev, S. K., Umezawa, K., Islamgulov, D. V., et al. (2013) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2013.03.017 · Cited by 31 · see citing works

Lymphotoxin network pathways shape the tumor microenvironment

Bjordahl, R., Steidl, C., Gascoyne, R. D., & Ware, C. F. (2013) · Current Opinion in Immunology · doi:10.1016/j.coi.2013.01.001 · Cited by 31 · see citing works

Differentiation and Activation of γδ T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors

Ribot, J. C., & Silva‐Santos, B. (2013) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-6217-0_11 · Cited by 27 · see citing works

B and T lymphocyte attenuator is highly expressed on intrahepatic T cells during chronic HBV infection and regulates their function

Cai, G., Nie, X., Li, L., Hu, L., Wu, B., Lin, J., Jiang, C., Wang, H., Wang, X., & Shen, Q. (2013) · Journal of Gastroenterology · doi:10.1007/s00535-013-0762-9 · Cited by 27 · see citing works

Human CD4+CD3− Innate-Like T Cells Provide a Source of TNF and Lymphotoxin-αβ and Are Elevated in Rheumatoid Arthritis

Bekiaris, V., Šedý, J. R., Rossetti, M. M., Spreafico, R., Sharma, S., Rhode-Kurnow, A., Ware, B. C., Huang, N., Macauley, M. G., Norris, P. S., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301672 · Cited by 26 · see citing works

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

Nurieva, R., Chung, Y., Hwang, D., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.07.010 · Cited by 25 · see citing works

Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis

Perdigones, N., Vigo, A., Lamas, J. R., et al. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27292 · Cited by 24 · see citing works

CD160 and BTLA: LIGHTs out for CD4+ T cells

Kaye, J. G. (2008) · Nature Immunology · doi:10.1038/ni0208-122 · Cited by 23 · see citing works

Proinflammatory and prothrombotic effects on human vascular endothelial cells of Immune-cell-derived LIGHT

Çelik, Ş., Shankar, V., Richter, A., et al. (2009) · European journal of medical research · doi:10.1186/2047-783x-14-4-147 · Cited by 23 · see citing works

γ δ T Cell Modulation in Anticancer Treatment

Caccamo, N., Dieli, F., Meraviglia, S., Guggino, G., & Salerno, A. (2010) · Current Cancer Drug Targets · doi:10.2174/156800910790980188 · Cited by 23 · see citing works

The Expression and Anatomical Distribution of BTLA and Its Ligand HVEM in Rheumatoid Synovium

Shang, Y., Guo, G., Cui, Q., Li, J., Ruan, Z., & Chen, Y. (2011) · Inflammation · doi:10.1007/s10753-011-9417-2 · Cited by 22 · see citing works

Increased plasma LIGHT levels in patients with atopic dermatitis

Kotani, H., Masuda, K., Tamagawa‐Mineoka, R., et al. (2012) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2012.04576.x · Cited by 20 · see citing works

Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition

Blanco‐Kelly, F., Álvarez‐Lafuente, R., Alcina, A., Abad‐Grau, M. M., Heras, V. D. L., Lucas, M., de la Concha, E. G., Fernández, Ó., Arroyo, R., Matesanz, F., et al. (2010) · Genes and Immunity · doi:10.1038/gene.2010.42 · Cited by 18 · see citing works

NK cells protect secondary lymphoid tissue from cytomegalovirus via a CD30‐dependent mechanism

Bekiaris, V., Gaspal, F., McConnell, F. M., et al. (2009) · European Journal of Immunology · doi:10.1002/eji.200939508 · Cited by 17 · see citing works

NKG 2C, HLA ‐E and their association with psoriasis

Patel, F., Marusina, A. I., Duong, C., et al. (2013) · Experimental Dermatology · doi:10.1111/exd.12280 · Cited by 16 · see citing works

Enhanced plasma levels of LIGHT in patients with acute atherothrombotic stroke

Liu, G.-Z., Fang, L.-B., Hjelmström, P., et al. (2008) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2008.01013.x · Cited by 15 · see citing works

Engagement of the CD160 activating NK cell receptor leads to its association with CD2 in circulating human NK cells

Rabot, M., Bensussan, A., & Bouteiller, P. L. (2006) · Transplant Immunology · doi:10.1016/j.trim.2006.09.031 · Cited by 13 · see citing works

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

Cai, Y., Shen, X., Ding, C., Qi, C., Li, K., Li, X., Jala, V. R., Zhang, H., Wang, T., Zheng, J., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.10.006 · Cited by 13 · see citing works

Possible Pathogenic Role of the Transmembrane Isoform of CD160 NK Lymphocyte Receptor in Paroxysmal Nocturnal Hemoglobinuria

Giustiniani, J., Sabour-Alaoui, S., Bernard, J., et al. (2012) · Current Molecular Medicine · doi:10.2174/156652412798889081 · Cited by 11 · see citing works

Promoter sequence variants of LIGHT are associated with female vascular dementia

Kong, M., Kim, Y., & Lee, C. (2008) · Journal of Biomedical Science · doi:10.1007/s11373-008-9242-2 · Cited by 8 · see citing works

[BTLA Characterization and its association with disease progression in patients with chronic HIV-1 infection.].

Xu, X., Zhang, Z., Gu, L.-L., et al. (2009) · PubMed · Cited by 6 · see citing works

Inhibiting inhibitory pathways in human γδ T cells

Lopez, R. D. (2013) · Blood · doi:10.1182/blood-2013-06-506584 · Cited by 4 · see citing works

[Expression of the costimulatory molecule BTLA in synovial tissues from rheumatoid arthritis patients].

Shang, Y., Cui, Q., Li, J., et al. (2012) · PubMed · Cited by 4 · see citing works

Innate B cells: oxymoron or validated concept?

Ware, C. F., & Benedict, C. A. (2012) · F1000Research · doi:10.12688/f1000research.1-8.v1 · Cited by 3 · see citing works

B Cells, Not Just for Antibody Anymore

Khanna, K. M., & Lefrançois, L. (2012) · Immunity · doi:10.1016/j.immuni.2012.02.011 · Cited by 3 · see citing works

Innate B cells: oxymoron or validated concept?

Ware, C. F., & Benedict, C. A. (2012) · F1000Research · doi:10.3410/f1000research.1-8.v1 · Cited by 2 · see citing works

B and T Lymphocyte Attenuator Down-regulation by HIV-1 Depends on Type I Interferon and Contributes to T-Cell Hyperactivation

Su, L., Fu, Y., Gu, L., et al. (2020) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/hcym-3s38 · Cited by 1 · see citing works

B and T lymphocyte attenuator tempers early infection immunity (133.6)

Brown, N. K., Sun, Y., Miller, M. L., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.supp.133.6 · Cited by 1 · see citing works

The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses

Ward-Kavanagh, L. K., Lin, W. W., Šedý, J. R., & Ware, C. F. (2016) · Immunity · doi:10.1016/j.immuni.2016.04.019 · Cited by 463 · see citing works

Chromosomal-level reference genome assembly of muskox (Ovibos moschatus) from Banks Island in the Canadian Arctic, a resource for conservation genomics

Lok, S., Lau, T. N. H., Trost, B., Tong, A. H. Y., Paton, T., Wintle, R. F., Engstrom, M. D., Gunn, A., & Scherer, S. W. (2024) · Scientific Reports · doi:10.1038/s41598-024-67270-9 · Cited by 4 · see citing works

Distinct Roles of the Two Tumor Necrosis Factor (TNF) Receptors in Modulating TNF and Lymphotoxin α Effects

Medvedev, A. E., Espevik, T., Ranges, G. E., & Sundan, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.16.9778 · Cited by 113 · see citing works

[Function, molecular structure and gene expression regulation of tumor necrosis factor and lymphotoxin].

Higashi, N. (1992) · PubMed · Cited by 1 · see citing works

Inhibition of ligand binding and antiproliferative effects of tumor necrosis factor and lymphotoxin by soluble forms of recombinant P60 and P80 receptors

Higuchi, M., & Aggarwal, B. B. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)91780-t · Cited by 33 · see citing works

Lymphotoxin Beta Receptor Signaling in Intestinal Epithelial Cells Orchestrates Innate Immune Responses against Mucosal Bacterial Infection

Wang, Y., Koroleva, E. P., Kruglov, A., Kuprash, D. V., Nedospasov, S. A., Fu, Y., & Tumanov, A. V. (2010) · Immunity · doi:10.1016/j.immuni.2010.02.011 · Cited by 154 · see citing works

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor

Grell, M., Wajant, H., Zimmermann, G., & Scheurich, P. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.2.570 · Cited by 478 · see citing works