The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms
Open accessAbstract
The term ‘quorum sensing’ (QS) is generally used to describe the phenomenon that bacteria release and perceive signal molecules to coordinate cooperative behaviour in response to their population size. QS-based communication has therefore been considered a social trait. Here we show that QS signals (N-acyl-homoserine lactones, AHLs) are stochastically produced in young biofilms of Pseudomonas putida and act mainly as self-regulatory signals rather than inducing neighbouring cells. We demonstrate that QS induces the expression of putisolvin biosurfactants that are not public goods, thereby triggering asocial motility of induced cells out of microcolonies. Phenotypic heterogeneity is most prominent in the early stages of biofilm development, whereas at later stages behaviour patterns across cells become more synchronized. Our findings broaden our perspective on QS by showing that AHLs can control the expression of asocial (self-directed) traits, and that heterogeneity in QS can serve as a mechanism to drive phenotypic heterogeneity in self-directed behaviour.
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Sociomicrobiology: the connections between quorum sensing and biofilms
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Look who's talking: communication and quorum sensing in the bacterial world
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Bacterial quorum sensing in complex and dynamically changing environments
Mukherjee, S., & Bassler, B. L. (2019) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0186-5 · Cited by 1,374
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Single-cell landscape of immunological responses in patients with COVID-19
Zhang, J.-Y., Wang, X.-M., Xing, X., Xu, Z., Zhang, C., Song, J.-W., Fan, X., Xia, P., Fu, J.-L., Wang, S.-Y., et al. (2020) · Nature Immunology · doi:10.1038/s41590-020-0762-x · Cited by 642
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Metadata
- Authors
- Cárcamo-Oyarce, G., Lumjiaktase, P., Kümmerli, R., & Eberl, L.
- Venue
- Nature Communications
- Published
- 2015-01-16
- Volume
- 6
- Issue
- 1
- Pages
- 5945-5945
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2045387875
- Cited by
- 958
- References
- 37
- FWCI
- 16.98
- Type
- journal article
- Language
- en
- Open access
- gold
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- Cárcamo-Oyarce, G., Lumjiaktase, P., Kümmerli, R., & Eberl, L. (2015). Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms. Nature Communications. https://doi.org/10.1038/ncomms6945
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
