Advantages and pitfalls in the application of mixed-model association methods

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1. Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits
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2. Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation
   Jianjun Gao, Lea Karatheodoris Davis, Amy B. Hart, Sandra Sanchez‐Roige, Lide Han, John T. Cacioppo, Abraham A. Palmer · 2016 · Neuropsychopharmacology
3. Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia
   Tucci, Serena, Vohr, Samuel H., McCoy, Rajiv C., Vernot, Benjamin, Robinson, Matthew R., Barbieri, Chiara, Nelson, Brad J., Fu, Wenqing, Purnomo, Gludhug A., Sudoyo, Herawati et al. · 2018 · Science
4. Statistical power in genome-wide association studies and quantitative trait locus mapping
   Meiyue Wang, Shizhong Xu · 2019 · Heredity
5. Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
   Dan Liang, Angela L. Elwell, Nil Aygün, Oleh Krupa, Justin M. Wolter, Felix A. Kyere, Michael J. Lafferty, Kerry E. Cheek, Kenan P. Courtney, Marianna Yusupova et al. · 2021 · Nature Neuroscience
6. Molecular quantitative trait loci
   Aguet, François, Alasoo, Kaur, Li, Yang I., Battle, Alexis, Im, Hae Kyung, Montgomery, Stephen B., Lappalainen, Tuuli · 2023 · Nature Reviews Methods Primers
7. Genomic prediction and GWAS of yield, quality and disease-related traits in spring barley and winter wheat
   Hsin‐Yuan Tsai, Luc Janss, Jeppe Reitan Andersen, Jihad Orabi, Jens Due Jensen, Ahmed Jahoor, Just Jensen · 2020 · Scientific Reports
8. Genomic variants affecting homoeologous gene expression dosage contribute to agronomic trait variation in allopolyploid wheat
   Fei He, Wei Wang, William B. Rutter, Katherine W. Jordan, Jie Ren, Ellie Taagen, Noah DeWitt, Deepmala Sehgal, Sivakumar Sukumaran, Susanne Dreisigacker et al. · 2022 · Nature Communications
9. Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits
   Brian C. Zhang, Arjun Biddanda, Árni Freyr Gunnarsson, Fergus Cooper, Pier Francesco Palamara · 2023 · Nature Genetics
10. The Complex and Diverse Genetic Architecture of Dilated Cardiomyopathy
    Ray E. Hershberger, Jason R. Cowan, Elizabeth Jordan, Daniel D. Kinnamon · 2021 · Circulation Research
11. Rare variants contribute disproportionately to quantitative trait variation in yeast
    Joshua S. Bloom, James Boocock, Sebastian Treusch, Meru J. Sadhu, Laura Day, Holly Oates-Barker, Leonid Kruglyak · 2019 · eLife
12. Genetic Basis of Variation in Rice Seed Storage Protein (Albumin, Globulin, Prolamin, and Glutelin) Content Revealed by Genome-Wide Association Analysis
    Pingli Chen, Zhikang Shen, Luchang Ming, Yibo Li, Wenhan Dan, Guangming Lou, Bo Peng, Bian Wu, Yanhua Li, Zhao Da et al. · 2018 · Frontiers in Plant Science
13. Imputation to whole-genome sequence using multiple pig populations and its use in genome-wide association studies
    Sanne van den Berg, Jérémie Vandenplas, Fred A. van Eeuwijk, A.C. Bouwman, Marcos S. Lopes, Roel F. Veerkamp · 2019 · Genetics Selection Evolution
14. Current Affairs of Microbial Genome-Wide Association Studies: Approaches, Bottlenecks and Analytical Pitfalls
    James Emmanuel San, Shakuntala Baichoo, Aquillah M. Kanzi, Yumna Moosa, Richard J. Lessells, Vagner Fonseca, John Mogaka, Robert A. Power, Túlio de Oliveira · 2020 · Frontiers in Microbiology
15. The effect of X-linked dosage compensation on complex trait variation
    Sidorenko, Julia, Kassam, Irfahan, Kemper, Kathryn E., Zeng, Jian, Lloyd-Jones, Luke R., Montgomery, Grant W., Gibson, Greg, Metspalu, Andres, Esko, Tonu, Yang, Jian et al. · 2019 · Nature Communications
16. Estimating SNP-Based Heritability and Genetic Correlation in Case-Control Studies Directly and with Summary Statistics.
    Omer Weissbrod, J. Flint, Saharon Rosset · 2018 · American Journal of Human Genetics
17. Genome-Wide Association Studies in Diverse Spring Wheat Panel for Stripe, Stem, and Leaf Rust Resistance
    Deepender Kumar, Animesh Kumar, Vinod Chhokar, Om Prakash Gangwar, Subhash Chander Bhardwaj, M. Sivasamy, S V Sai Prasad, T.L.Prakasha, Hanif Khan, Rajender Singh et al. · 2020 · Frontiers in Plant Science
18. Linkage disequilibrium and genome-wide association analysis for anthocyanin pigmentation and fruit color in eggplant
    Fabio Cericola, Ezio Portis, Sergio Lanteri, Laura Toppino, Lorenzo Barchi, N. Acciarri, Laura Pulcini, Tea Sala, Giuseppe Leonardo Rotino · 2014 · BMC Genomics
19. Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank
    Lynsey S. Hall, Mark J. Adams, Aleix Arnau‐Soler, Toni‐Kim Clarke, David M. Howard, Yanni Zeng, Gail Davies, Saskia P. Hagenaars, Ana Maria Fernandez-Pujals, Jude Gibson et al. · 2018 · Translational Psychiatry
20. The Genetic Architecture of Fitness Drives Population Viability during Rapid Environmental Change
    Marty D. Kardos, Gordon Luikart · 2021 · The American Naturalist
21. Factors associated with sharing e-mail information and mental health survey participation in large population cohorts
    Mark J. Adams, William David Hill, David M. Howard, Hassan S. Dashti, Katrina A. S. Davis, Archie Campbell, Toni‐Kim Clarke, Ian J. Deary, Caroline Hayward, David John Porteous et al. · 2019 · International Journal of Epidemiology
22. Open problems in human trait genetics
    Nadav Brandes, Omer Weissbrod, Michal Linial · 2022 · Genome biology
23. NAM: association studies in multiple populations
    Alencar Xavier, Shizhong Xu, William M. Muir, Katy Martin Rainey · 2015 · Bioinformatics
24. The distribution of common-variant effect sizes
    O’Connor, Luke J. · 2021 · Nature Genetics
25. Genetic Predisposition to Ischemic Stroke
    Tsuyoshi Hachiya, Yoichiro Kamatani, Atsushi Takahashi, Jun Hata, Ryohei Furukawa, Yuh Shiwa, Taiki Yamaji, Megumi Hara, Kozo Tanno, Hideki Ohmomo et al. · 2016 · Stroke
26. Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits
    Chia‐Yen Chen, Tzu‐Ting Chen, Yen‐Chen Anne Feng, Mingrui Yu, Shu‐Chin Lin, Ryan J. Longchamps, Shi‐Heng Wang, Yi‐Hsiang Hsu, Hwai‐I Yang, Po‐Hsiu Kuo et al. · 2023 · Cell Genomics
27. Identifying loci affecting trait variability and detecting interactions in genome-wide association studies
    Alexander I. Young, Fabian L. Wauthier, Peter Donnelly · 2018 · Nature Genetics
28. Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP
    Eleanor M. Wigmore, Jonathan D. Hafferty, Lynsey S. Hall, David M. Howard, Toni‐Kim Clarke, Chiara Fabbri, Cathryn M. Lewis, Rudolf Uher, Lauren B. Navrady, Mark J. Adams et al. · 2019 · The Pharmacogenomics Journal
29. Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores
    Rafik Tadros, Hanno L. Tan, ESCAPE-NET Investigators, Sulayman el Mathari, Jan A. Kors, Pieter Gerard Postema, Najim Lahrouchi, Leander Beekman, Milena Radivojkov‐Blagojevic, Ahmad S. Amin et al. · 2019 · European Heart Journal
30. Genome-wide association study for conformation traits in three Danish pig breeds
    Thu Hong Le, Ole Fredslund Christensen, Bjarne Nielsen, Goutam Sahana · 2017 · Genetics Selection Evolution
31. The Contribution of Inflammation to the Development of Hypertension Mediated by Increased Arterial Stiffness
    Hirofumi Tomiyama, Kazuki Shiina, Chisa Matsumoto‐Nakano, Toshiharu Ninomiya, Shunsuke Komatsu, Kazutaka Kimura, Taishiro Chikamori, Akira Yamashina · 2017 · Journal of the American Heart Association
32. Embracing polygenicity: a review of methods and tools for psychiatric genetics research
    R. M. Maier, Peter M. Visscher, Matthew R. Robinson, Naomi R. Wray · 2017 · Psychological Medicine
33. Interpreting population- and family-based genome-wide association studies in the presence of confounding
    Carl Veller, Graham Coop · 2024 · PLoS Biology
34. Environment dominates over host genetics in shaping human gut microbiota
    Daphna Rothschild, Omer Weissbrod, Elad Barkan, Alexander Kurilshikov, Tal Korem, David Zeevi, Paul Igor Costea, Anastasia Godneva, Kalka IN, Bar N · 2018 · Yearbook of pediatric endocrinology
35. Genetics of rheumatic fever and rheumatic heart disease
    Babu Muhamed, Tom Parks, Karen S Sliwa · 2019 · Nature Reviews Cardiology
36. Further Improvements to Linear Mixed Models for Genome-Wide Association Studies
    Christian Widmer, Christoph Lippert, Omer Weissbrod, Nicolò Fusi, Carl Myers Kadie, Robert I Davidson, Jennifer Listgarten, David E. Heckerman · 2014 · Scientific Reports
37. Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray
    Jonathan R. I. Coleman, Jack Euesden, Hamel Patel, Amos Folarin, Stephen Newhouse, Gerome D. Breen · 2015 · Briefings in Functional Genomics
38. Enabling Privacy-Preserving GWASs in Heterogeneous Human Populations
    Sean Simmons, S. Cenk Şahinalp, Bonnie Berger · 2016 · Cell Systems
39. Genetic aetiology of self-harm ideation and behaviour
    Campos, Adrian I., Verweij, Karin J. H., Statham, Dixie J., Madden, Pamela A. F., Maciejewski, Dominique F., Davis, Katrina A. S., John, Ann, Hotopf, Matthew, Heath, Andrew C., Martin, Nicholas G. et al. · 2020 · Scientific Reports
40. Genetic architecture of quantitative traits in beef cattle revealed by genome wide association studies of imputed whole genome sequence variants: II: carcass merit traits
    Yining Wang, Feng Zhang, Robert Mukiibi, Liuhong Chen, Michael D. Vinsky, Graham Stuart Plastow, J. A. Basarab, Paul Stothard, Changxi Li · 2020 · BMC Genomics
41. Genome-wide association analysis reveals new insights into the genetic architecture of defensive, agro-morphological and quality-related traits in cassava
    Ismail Yusuf Rabbi, Siraj Ismail Kayondo, Guillaume Jean Bauchet, Muyideen Yusuf, Cynthia Idhigu Aghogho, Kayode Ogunpaimo, Ruth Uwugiaren, Ikpan Andrew Smith, Prasad Peteti, Afolabi Agbona et al. · 2020 · Plant Molecular Biology
42. Genetic Mechanisms Leading to Sex Differences Across Common Diseases and Anthropometric Traits
    Michela Traglia, Dina N. F. Bseiso, Alexander Gusev, Brigid Adviento, Daniel Park, Joel Mefford, Noah Zaitlen, Lauren A. Weiss · 2016 · Genetics
43. Extended High-frequency Hearing Impairment Despite a Normal Audiogram: Relation to Early Aging, Speech-in-noise Perception, Cochlear Function, and Routine Earphone Use
    Srikanta Kumar Mishra, Udit Saxena, Hansapani Rodrigo · 2021 · Ear and Hearing
44. Involvement of Arterial Stiffness and Inflammation in Hyperuricemia-Related Development of Hypertension
    Hirofumi Tomiyama, Kazuki Shiina, Charalambos V. Vlachopoulos, Yoichi Iwasaki, Chisa Matsumoto, Kazutaka Kimura, Masatsune Fujii, Taishiro Chikamori, Akira Yamashina · 2018 · Hypertension
45. Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder
    Seon-Kyeong Jang, Gretchen Saunders, Mengzhen Liu, Yu Jiang, Dajiang J. Liu, Scott I. Vrieze · 2020 · Psychological Medicine
46. Heterogeneity of genetic architecture of body size traits in a free‐living population
    Camillo Bérénos, Philip A. Ellis, Jill G. Pilkington, Sang Lee, Jacob Gratten, Josephine M. Pemberton · 2015 · Molecular Ecology
47. A Genome-Wide Association Study Identifies Multiple Regions Associated with Head Size in Catfish
    Xin Geng, Shikai Liu, Jun Yao, Lisui Bao, Jiaren Zhang, Chao Li, Ruijia Wang, Jin Sha, Peng Zeng, Degui Zhi et al. · 2016 · G3 Genes Genomes Genetics
48. A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia
    Sophie E. Legge, Antonio F. Pardiñas, Marinka Helthuis, John A. Jansen, Karel Jollie, Steven Knapper, James Hunter MacCabe, Dan Rujescu, David Andrew Collier, Michael C. O’Donovan et al. · 2019 · Molecular Psychiatry
49. A scalable variational inference approach for increased mixed-model association power
    Hrushikesh Loya, Georgios Kalantzis, Fergus Cooper, Pier Francesco Palamara · 2025 · Nature Genetics
50. Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches
    Alessandra Mozzi, Chiara Pontremoli, Manuela Sironi · 2017 · Infection Genetics and Evolution
51. Differential expression analysis for RNAseq using Poisson mixed models
    Shiquan Sun, Michelle M. Hood, Laura J. Scott, Qinke Peng, Sayan Mukherjee, Jenny Tung, Xiang Zhou · 2017 · Nucleic Acids Research
52. Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
    Carolina Makowski, Dennis van der Meer, Weixiu Dong, Hao Wang, Yan Wu, Jingjing Zou, Cin Liu, Sara B. Rosenthal, Donald J. Hagler, Chun Chieh Fan et al. · 2022 · Science
53. Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies
    Alexander F. Gileta, Christopher J. Fitzpatrick, Apurva S. Chitre, Celine L. St. Pierre, Elizabeth V. Joyce, Rachael J. Maguire, Africa M. McLeod, Natalia M. Gonzales, April E. Williams, Jonathan D. Morrow et al. · 2022 · PLoS Genetics
54. Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination
    Luisa F. Pallares, Peter S. Carbonetto, Shyam Gopalakrishnan, Clarissa C. Parker, Cheryl L. Ackert‐Bicknell, Abraham A. Palmer, Diethard Tautz · 2015 · PLoS Genetics
55. Community-wide genome sequencing reveals 30 years of Darwin’s finch evolution
    Enbody, Erik D., Sendell-Price, Ashley T., Sprehn, C. Grace, Rubin, Carl-Johan, Visscher, Peter M., Grant, B. Rosemary, Grant, Peter R., Andersson, Leif · 2023 · Science
56. Dissection of additive, dominance, and imprinting effects for production and reproduction traits in Holstein cattle
    Jicai Jiang, Botong Shen, Jeffrey R. O’Connell, Paul Michael VanRaden, John B. Cole, Li Ma · 2017 · BMC Genomics
57. Inferring Gene-by-Environment Interactions with a Bayesian Whole-Genome Regression Model
    Matthew Kerin, Jonathan Marchini · 2020 · The American Journal of Human Genetics
58. Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility
    Fengzhe Xu, Evan Yi-Wen Yu, Xue Cai, Liang Yue, Lipeng Jing, Xinxiu Liang, Yuanqing Fu, Zelei Miao, Min Yang, Menglei Shuai et al. · 2023 · Nature Communications
59. Mixed Model with Correction for Case-Control Ascertainment Increases Association Power
    Tristan J. Hayeck, Noah Zaitlen, Po‐Ru Loh, Bjarni Jóhann Vilhjálmsson, Samuela J Pollack, Alexander Gusev, Jian Yang, Guo‐Bo Chen, Michael Edward Goddard, Peter M. Visscher et al. · 2015 · The American Journal of Human Genetics
60. Profiling and Leveraging Relatedness in a Precision Medicine Cohort of 92,455 Exomes
    Jeffrey C. Staples, Evan K. Maxwell, Nehal Gosalia, Claudia G. Gonzaga-Jauregui, Christopher Snyder, Alicia C. Hawes, John Penn, Ricardo H. Ulloa, Xiaodong Bai, Alexander E. Lopez et al. · 2018 · The American Journal of Human Genetics
61. Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci
    Rupal L. Shah, Jeremy A. Guggenheim · 2018 · Human Genetics
62. Mapping the sensory perception of apple using descriptive sensory evaluation in a genome wide association study
    Beatrice Amyotte, Amy J. Bowen, Travis W. Banks, Istvan Rajcan, Daryl J. Somers · 2017 · PLoS ONE
63. A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle
    Young-Lim Lee, Haruko Takeda, Gabriel Costa Monteiro Moreira, Latifa Karim, Erik Mullaart, Wouter R. Coppieters, Ruth Appeltant, Roel F. Veerkamp, Martien A. M. Groenen, Michel Georges et al. · 2021 · PLoS Genetics
64. Improving the Power of GWAS and Avoiding Confounding from Population Stratification with PC-Select
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65. Genome-wide mapping of 10 calving and fertility traits in Holstein dairy cattle with special regard to chromosome 18
    Magdeburg Müller, Sophie Rothammer, Doris Seichter, I. Russ, Dirk Hinrichs, Jens Tetens, Georg Erwin Thaller, Ivica Međugorac · 2017 · Journal of Dairy Science
66. Genetic modifiers of Mendelian disease: Huntington’s disease and the trinucleotide repeat disorders
    Peter Holmans, Thomas H. Massey, Lesley Jones · 2017 · Human Molecular Genetics
67. Getting the most out of intensive longitudinal data: a methodological review of workload–injury studies
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68. Mendelian randomization: the challenge of unobserved environmental confounds
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69. Leveraging population admixture to characterize the heritability of complex traits
    Zaitlen, Noah, Pasaniuc, Bogdan, Sankararaman, Sriram, Bhatia, Gaurav, Zhang, Jianqi, Gusev, Alexander, Young, Taylor, Tandon, Arti, Pollack, Samuela, Vilhjálmsson, Bjarni J et al. · 2014 · Nature Genetics
70. Gene expression networks in the Drosophila Genetic Reference Panel
    Logan J. Everett, Wen Huang, Shanshan Zhou, Mary Anna Carbone, Richard F. Lyman, Gunjan H Arya, Matthew S. Geisz, Junwu Ma, Fabio Morgante, Genevieve St. Armour et al. · 2020 · Genome Research
71. A QTL for Number of Teats Shows Breed Specific Effects on Number of Vertebrae in Pigs: Bridging the Gap Between Molecular and Quantitative Genetics
    Maren van Son, Marcos S. Lopes, Henry J. Martell, Martijn F. L. Derks, Lars Erik Gangsei, Jørgen Kongsro, Mark N. Wass, Eli H. Grindflek, B. Harlizius · 2019 · Frontiers in Genetics
72. Variants at the ASIP locus contribute to coat color darkening in Nellore cattle
    Beatriz Batista Trigo, Adam Taiti Harth Utsunomiya, Alvaro A. A. D. Fortunato, Marco Milanesi, Rafaela Beatriz Pintor Torrecilha, Harrison J. Lamb, Loan T Nguyen, Elizabeth M. Ross, Ben J. Hayes, Rômulo C. M. Padula et al. · 2021 · Genetics Selection Evolution
73. Heritability of body size in the polar bears of Western Hudson Bay
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74. Multiple testing correction in linear mixed models
    Jong Wha J. Joo, Farhad Hormozdiari, Buhm Han, Eleazar Eskin · 2016 · Genome biology
75. Multi-ethnic polygenic risk scores improve risk prediction in diverse populations
    Carla Márquez‐Luna, Po‐Ru Loh, Alkes L. Price · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
76. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
    Gusev, Alexander, Shi, Huwenbo, Kichaev, Gleb, Pomerantz, Mark, Li, Fugen, Long, Henry W., Ingles, Sue A., Kittles, Rick A., Strom, Sara S., Rybicki, Benjamin A. et al. · 2016 · Nature Communications
77. Genome-Wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2
    Hernandez Cordero, Ana I., Gonzales, Natalia M., Parker, Clarissa C., Sokolof, Greta, Vandenbergh, David J., Cheng, Riyan, Abney, Mark, Sko, Andrew, Douglas, Alex, Palmer, Abraham A. et al. · 2019 · The American Journal of Human Genetics
78. Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis
    Nil Aygün, Angela L. Elwell, Dan Liang, Michael J. Lafferty, Kerry E. Cheek, Kenan P. Courtney, Jessica T. Mory, Ellie Hadden-Ford, Oleh Krupa, Luis de la Torre-Ubieta et al. · 2021 · The American Journal of Human Genetics
79. Deep Learning for Genomics: From Early Neural Nets to Modern Large Language Models
    Tianwei Yue, Yuanxin Wang, Longxiang Zhang, Chunming Gu, Haoru Xue, Wenping Wang, Qi Lyu, Yujie Dun · 2023 · International Journal of Molecular Sciences
80. Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries
    Bryan R. Gorman, Georgios Voloudakis, Robert P. Igo, Tyler G. Kinzy, Christopher W. Halladay, Tim B. Bigdeli, Biao Zeng, Sanan Venkatesh, Jessica N. Cooke Bailey, Dana C. Crawford et al. · 2024 · Nature Genetics
81. Genome-wide association study for longevity with whole-genome sequencing in 3 cattle breeds
    Qianqian Zhang, Bernt Guldbrandtsen, Jørn Rind Thomasen, Mogens Sandø Lund, Goutam Sahana · 2016 · Journal of Dairy Science
82. Sketching algorithms for genomic data analysis and querying in a secure enclave
    Can Koçkan, Kaiyuan Zhu, Natnatee Dokmai, Nikolai Karpov, Muhammed Oğuzhan Külekci, David Paul Woodruff, S. Cenk Şahinalp · 2020 · Nature Methods
83. Distinguishing pleiotropy from linked QTL between milk production traits and mastitis resistance in Nordic Holstein cattle
    Zexi Cai, Magdalena Dusza, Bernt Guldbrandtsen, Mogens Sandø Lund, Goutam Sahana · 2020 · Genetics Selection Evolution
84. Recent advances in the study of fine-scale population structure in humans
    John Novembre, Benjamin Marco Peter · 2016 · Current Opinion in Genetics & Development
85. Association Between Genetic Risk for Psychiatric Disorders and the Probability of Living in Urban Settings
    Jessye M. Maxwell, Jonathan R. I. Coleman, Gerome D. Breen, Evangelos Vassos · 2021 · JAMA Psychiatry
86. Significance testing and genomic inflation factor using high‐density genotypes or whole‐genome sequence data
    Sanne van den Berg, Jérémie Vandenplas, Fred A. van Eeuwijk, Marcos S. Lopes, Roel F. Veerkamp · 2019 · Journal of Animal Breeding and Genetics
87. Interactions between the lipidome and genetic and environmental factors in autism
    Chloe X. Yap, Anjali K. Henders, Gail A. Alvares, Corey Giles, Kevin Huynh, Anh Nguyen, Leanne M. Wallace, Tiana McLaren, Yuanhao Yang, Leanna M. Hernandez et al. · 2023 · Nature Medicine
88. Limitations of principal components in quantitative genetic association models for human studies
    Yiqi Yao, Alejandro Ochoa · 2023 · eLife
89. Invited review: Genome-wide association analysis for quantitative traits in livestock – a selective review of statistical models and experimental designs
    Markus Schmid, Jörn Bennewitz · 2017 · Archives animal breeding/Archiv für Tierzucht
90. Integration of selection signatures and multi-trait GWAS reveals polygenic genetic architecture of carcass traits in beef cattle
    Qunhao Niu, Tianliu Zhang, Ling Xu, Zezhao Wang, Zezhao Wang, Bo Zhu, Lupei Zhang, Huijiang Gao, Jiuzhou Song, Junya Li et al. · 2021 · Genomics
91. Genome-Wide Association Study of Meat Quality Traits in Hanwoo Beef Cattle Using Imputed Whole-Genome Sequence Data
    Mohammed Bedhane, Julius H. J. van der Werf, Cedric Gondro, Naomi Duijvesteijn, Dajeong Lim, Byoungho Park, Mi Na Park, Roh Seung Hee, Sam Clark · 2019 · Frontiers in Genetics
92. Identification of a haplotype associated with cholesterol deficiency and increased juvenile mortality in Holstein cattle
    S. Kipp, Dierck Segelke, Sven Schierenbeck, Friedrich Reinhardt, Reinhard Reents, Christine Wurmser, Hubert Pausch, Ruedi Fries, Georg Erwin Thaller, Jens Tetens et al. · 2016 · Journal of Dairy Science
93. Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
    Ali Akbari, Alison R. Barton, Steven Gazal, Zheng Li, Mohammadreza Kariminejad, Annabel Perry, Yating Zeng, Alissa Mittnik, Nick J. Patterson, Matthew Mah et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
94. Assessing statistical significance in multivariable genome wide association analysis
    Laura Buzdugan, Markus Kalisch, Arcadi Navarro, Daniel Schunk, Ernst Fehr, Peter Bühlmann · 2016 · Bioinformatics
95. Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
    Sara L. Pulit, Lu-Chen C Weng, Patrick F. McArdle, Ludovic Trinquart, Seung Hoan Choi, Braxton D. Mitchell, Jonathan M. Rosand, Paul I. W. de Bakker, Emelia J. Benjamin, Patrick T. Ellinor et al. · 2018 · Neurology Genetics
96. Association Study Reveals Genetic Loci Responsible for Arsenic, Cadmium and Lead Accumulation in Rice Grain in Contaminated Farmlands
    Xiu‐Yan Liu, Sunlu Chen, Mingxue Chen, Guangyong Zheng, Yu Peng, Xiaoliang Shi, Ping Qin, Xiangyang Xu, Sheng Teng · 2019 · Frontiers in Plant Science
97. The Beavis Effect in Next-Generation Mapping Panels in Drosophila melanogaster
    Elizabeth G. King, Anthony D. Long · 2017 · G3 Genes Genomes Genetics
98. Principals about principal components in statistical genetics
    Fentaw Abegaz, Kridsadakorn Chaichoompu, Emmanuelle Génin, David W. Fardo, Inke Regina König, Jestinah Mahachie John, Kristel Van Steen · 2018 · Briefings in Bioinformatics
99. Disease and Polygenic Architecture: Avoid Trio Design and Appropriately Account for Unscreened Control Subjects for Common Disease
    Peyrot, Wouter J., Boomsma, Dorret I., Penninx, Brenda W.J.H., Wray, Naomi R. · 2016 · The American Journal of Human Genetics
100. Multiple ancestral haplotypes harboring regulatory mutations cumulatively contribute to a QTL affecting chicken growth traits
     Yuzhe Wang, Xuemin Cao, Chenglong Luo, Zheya Sheng, Chunyuan Zhang, Cheng Bian, Chungang Feng, Jinxiu Li, Fei Gao, Yiqiang Zhao et al. · 2020 · Communications Biology