Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

Cited by (1,001)

Items 201–300 of 1,001

  1. Non-Alcoholic Fatty Liver Disease: From Pathogenesis to Clinical Impact
    Alfredo Caturano, Carlo Acierno, Riccardo Nevola, Pia Clara Pafundi, Raffaele Galiero, Luca Rinaldi, Teresa Salvatore, Luigi Elio Adinolfi, Ferdinando Carlo Sasso · 2021 · Processes
  2. Diagnosis of non-alcoholic fatty liver disease (NAFLD)
    Hannele Yki‐Järvinen · 2016 · Diabetologia
  3. Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors PPARs, FXR, and LXR in NASH
    Marica Cariello, Elena Piccinin, Antonio Moschetta · 2021 · Cellular and Molecular Gastroenterology and Hepatology
  4. Genetics of Venous Thrombosis: update in 2015
    Pierre Suchon, David‐Alexandre Trégouët, Pierre‐Emmanuel Morange · 2015 · Thrombosis and Haemostasis
  5. Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study
    Eric Trépo, Stefano Caruso, Jie Yang, Sandrine Imbeaud, Gabrielle Couchy, Quentin Bayard, Éric Letouzé, Nathalie Ganne‐Carrié, Christophe Moreno, Abderrahim Oussalah et al. · 2021 · The Lancet Oncology
  6. Aktualisierte S2k-Leitlinie nicht-alkoholische Fettlebererkrankung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – April 2022 – AWMF-Registernummer: 021–025
    E. Roeb, A. Canbay, H. Bantel, J. Bojunga, J. de Laffolie, M. Demir, U. Denzer, A. Geier, W. Hofmann, C. Hudert et al. · 2022 · Zeitschrift für Gastroenterologie - German Journal of Gastroenterology
  7. Nanobody and Nanozyme‐Enabled Immunoassays with Enhanced Specificity and Sensitivity
    Yidan Wang, Yunlei Xianyu · 2022 · Small Methods
  8. Genome‐wide Association Study and Meta‐analysis on Alcohol‐Associated Liver Cirrhosis Identifies Genetic Risk Factors
    Tae-Hwi Linus Schwantes-An, Rebecca Darlay, Philippe Mathurin, Steven Masson, Suthat Liangpunsakul, Sebastian Mueller, Guruprasad Padur Aithal, Florian Eyer, Dermot C. Gleeson, Andrew Thompson et al. · 2020 · Hepatology
  9. Genome‐Wide Association Study of NAFLD Using Electronic Health Records
    Cameron J. Fairfield, Thomas M Drake, Riinu Pius, Andrew D. Bretherick, Archie Campbell, David W. Clark, Jonathan Andrew Fallowfield, Caroline Hayward, Neil Cowan Henderson, Peter K. Joshi et al. · 2021 · Hepatology Communications
  10. Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats
    Fei Luo, Ēriks Šmagris, Sarah A. Martin, Goncalo Dias do Vale, Jeffrey G. McDonald, Justin A. Fletcher, Shawn C. Burgess, Helen H. Hobbs, Jonathan C. Cohen · 2021 · Cellular and Molecular Gastroenterology and Hepatology
  11. Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding
    Nemanja U. Jovicic, Ilija D. Jeftic, Ivan Jovanović, Gordana D. Radosavljevic, Nebojša Arsenijević, Miodrag L. Lukić, Nada N. Pejnovic · 2015 · PLoS ONE
  12. Prevalence and severity of nonalcoholic fatty liver disease by transient elastography: Genetic and metabolic risk factors in a general population
    Salvatore Petta, Vito Di Marco, Rosaria Maria Pipitone, Stefania Grimaudo, Carola Buscemi, Antonio Craxı̀, Silvio Buscemi · 2018 · Liver International
  13. Noninvasive fatty liver markers predict liver disease mortality in the U.S. population
    Aynur Ünalp–Arida, Constance E. Ruhl · 2015 · Hepatology
  14. Recent advances in lean NAFLD
    Ruohui Xu, Jiashu Pan, Wenjun Zhou, Guang Ji, Yanqi Dang · 2022 · Biomedicine & Pharmacotherapy
  15. Mouse models of nonalcoholic fatty liver disease (NAFLD): pathomechanisms and pharmacotherapies
    Tingyu Fang, Hua Wang, Xiaoyue Pan, Peter J. Little, Suowen Xu, Jianping Weng · 2022 · International Journal of Biological Sciences
  16. The Impact of Macronutrient Intake on Non-alcoholic Fatty Liver Disease (NAFLD): Too Much Fat, Too Much Carbohydrate, or Just Too Many Calories?
    Theresa Hydes, Uazman Alam, Daniel James Cuthbertson · 2021 · Frontiers in Nutrition
  17. Mediterranean Diet and Multi-Ingredient-Based Interventions for the Management of Non-Alcoholic Fatty Liver Disease
    Manuel Suárez, Noemí Boqué, Josep M Del Bas-Prior, Jordi Mayneris‐Perxachs, Lluı́s Arola, Antoni Caimari · 2017 · Nutrients
  18. Obesity and Endothelial Function
    Masato Kajikawa, Yukihito Higashi · 2022 · Biomedicines
  19. Hepatic Transmembrane 6 Superfamily Member 2 Regulates Cholesterol Metabolism in Mice
    Yanbo Fan, Haocheng Lu, Yanhong Guo, Tianqing Zhu, Minerva T. Garcia-Barrio, Zhisheng Jiang, Cristen J. Willer, Jifeng Zhang, Yujie Chen · 2016 · Gastroenterology
  20. TM6SF2 rs58542926 impacts lipid processing in liver and small intestine
    Elizabeth A. O’Hare, Rongze Yang, Laura M. Yerges‐Armstrong, Urmila Sreenivasan, Rebecca J. McFarland, Carmen C. Leitch, Meredith H. Wilson, Shilpa Narina, Alexis Gorden, Kathy A. Ryan et al. · 2016 · Hepatology
  21. Microbiota, Obesity and NAFLD
    Louis Ho Shing Lau, Sunny Hei Wong · 2018 · Advances in experimental medicine and biology
  22. Genetics of Hepatocellular Carcinoma: Approaches to Explore Molecular Diversity
    Stefano Caruso, Daniel R. O’Brien, Sean Patrick Cleary, Lewis Rowland Roberts, Jessica Zucman‐Rossi · 2020 · Hepatology
  23. High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease
    Hyunkyung Kim, Kenneth E. Westerman, Kirk Smith, Joshua Chiou, Joanne B. Cole, Timothy D. Majarian, Marcin von Grotthuss, Soo Heon Kwak, Jaegil Kim, Josep Maria Mercader et al. · 2022 · Diabetologia
  24. Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα
    Robert C. Bauer, Makoto Sasaki, Daniel M. Cohen, Jian Guo Cui, Mikhaila A Smith, Batuhan Yenilmez, David J. Steger, Daniel James Rader · 2015 · Journal of Clinical Investigation
  25. From the origin of NASH to the future of metabolic fatty liver disease
    A. Geier, D. Tiniakos, H. Denk, M. Trauner · 2021 · Gut
  26. Interferon lambda 4 rs368234815 TT>δG variant is associated with liver damage in patients with nonalcoholic fatty liver disease
    Salvatore Petta, Luca V. C. Valenti, Antonino Tuttolomondo, Paola Dongiovanni, Rosaria Maria Pipitone, Calogero Cammà, Daniela Cabibi, Vito Di Marco, Anna Ludovica Fracanzani, Sara Badiali et al. · 2017 · Hepatology
  27. PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis
    Edmondo Falleti, Annarosa Cussigh, Sara Cmet, Carlo Fabris, Pierluigi Toniutto · 2015 · Digestive and Liver Disease
  28. Significant positive association of endotoxemia with histological severity in 237 patients with non‐alcoholic fatty liver disease
    J. Pang, Weiqi Xu, Xinrong Zhang, Grace Lai‐Hung Wong, Anthony W.H. Chan, Hoi–Yun Chan, Chi‐Hang Tse, Sally She‐Ting Shu, Paul Cheung‐Lung Choi, Henry Lik‐Yuen Chan et al. · 2017 · Alimentary Pharmacology & Therapeutics
  29. Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet
    Singhal, Garima, Kumar, Gaurav, Chan, Suzanne, Fisher, ffolliott M., Ma, Yong, Vardeh, Hilde G., Nasser, Imad A., Flier, Jeffrey S., Maratos-Flier, Eleftheria · 2018 · Molecular Metabolism
  30. Nonalcoholic fatty liver disease in patients with psoriasis: a consequence of systemic inflammatory burden?
    Ronald B. Prussick, Luca Miele · 2017 · British Journal of Dermatology
  31. Microbiomics, Metabolomics, Predicted Metagenomics, and Hepatic Steatosis in a Population‐Based Study of 1,355 Adults
    Louise J. M. Alferink, Djawad Radjabzadeh, Nicole Stephanie Erler, Dina Vojinović, Carolina Medina‐Gómez, André Gerardus Uitterlinden, Robert Jacobus de Knegt, Najaf Amin, M. Arfan Ikram, Harry L.A. Janssen et al. · 2020 · Hepatology
  32. TM6SF2: Catch-22 in the Fight Against Nonalcoholic Fatty Liver Disease and Cardiovascular Disease?
    Bratati Kahali, Yang‐Lin Liu, Ann K. Daly, Christopher Paul Day, Quentin Mark Anstee, Elizabeth K. Speliotes · 2015 · Gastroenterology
  33. Emerging role of genomic analysis in clinical evaluation of lean individuals with NAFLD
    Vilarinho, Sílvia, Ajmera, Veeral, Zheng, Melanie, Loomba, Rohit · 2021 · Hepatology
  34. PNPLA3—A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease
    Xiaocheng Charlie Dong · 2019 · Frontiers in Medicine
  35. TM6SF2 G lu167 L ys polymorphism is associated with low levels of LDL ‐cholesterol and increased liver injury in obese children
    Anna Grandone, D. Cozzolino, Pierluigi Marzuillo, Grazia Cirillo, Anna Di Sessa, L. Ruggiero, M. R. Di Palma, Laura Perrone, Emanuele Miraglia del Giudice · 2015 · Pediatric Obesity
  36. Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity
    Carlos Jose Pirola, Silvia C. Sookoian · 2018 · World Journal of Gastroenterology
  37. Evaluation of Polygenic Determinants of Non-Alcoholic Fatty Liver Disease (NAFLD) By a Candidate Genes Resequencing Strategy
    Alessia Di Costanzo, Francesca Belardinilli, Diego Bailetti, Marialuisa Sponziello, Laura D’Erasmo, Licia Polimeni, Francesco Baratta, Daniele Pastori, Fabrizio Ceci, Anna Montali et al. · 2018 · Scientific Reports
  38. Type 2 Diabetes: Multiple Genes, Multiple Diseases
    Miriam S. Udler · 2019 · Current Diabetes Reports
  39. Pharmacological treatment for metabolic dysfunction–associated steatotic liver disease and related disorders: Current and emerging therapeutic options
    Xiang Zhang, Harry Cheuk-Hay Lau, Jun Qing Yu · 2025 · Pharmacological Reviews
  40. Genetics of Type 2 Diabetes: Past, Present, and Future
    Markku Laakso, Lilian Fernandes Silva · 2022 · Nutrients
  41. Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis
    Pierre Nahon, Jessica Bamba‐Funck, Richard Layese, Eric Trépo, Jessica Zucman‐Rossi, Carole Cagnot, Nathalie Ganne‐Carrié, Cendrine Chaffaut, Erwan Guyot, Marianne Ziol et al. · 2022 · Journal of Hepatology
  42. Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy
    Yu‐Cheng Lin, Pi‐Feng Chang, Hsueh-Fang Lin, Kevin G. Liu, Mei‐Hwei Chang, Yen‐Hsuan Ni · 2016 · Journal of Hepatology
  43. A Nutrigenomic Approach to Non-Alcoholic Fatty Liver Disease
    Paola Dongiovanni, Luca V. C. Valenti · 2017 · International Journal of Molecular Sciences
  44. VLDL Biogenesis and Secretion: It Takes a Village
    Willemien Heerema-van Zwol, Bart van de Sluis, Henry N. Ginsberg, Jan Albert Kuivenhoven · 2024 · Circulation Research
  45. Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD
    Claudia Daniela Fuchs, Thierry Claudel, Michael Trauner · 2014 · Trends in Endocrinology and Metabolism
  46. Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease
    Zeyneb Kurt, Rio Barrere‐Cain, Jonnby S. LaGuardia, Margarete Mehrabian, Calvin Pan, Simon T. Y. Hui, Frode Norheim, Zhiqiang Zhou, Yehudit Hasin-Brumshtein, Aldons Jake Lusis et al. · 2018 · Biology of Sex Differences
  47. Sex hormone–binding globulin: biomarker and hepatokine?
    Pomme I. H. G. Simons, Olivier Valkenburg, Coen D.A. Stehouwer, Martijn C.G.J. Brouwers · 2021 · Trends in Endocrinology and Metabolism
  48. Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study
    Jeffrey Y. Cui, Chi‐Hua Chen, Min‐Tzu Lo, Nicholas J. Schork, Ricki Bettencourt, Monica P. Gonzalez, Archana Bhatt, Jonathan C. Hooker, Katherine M. Shaffer, Karen E. Nelson et al. · 2016 · Hepatology
  49. Association of Nonalcoholic Fatty Liver Disease with Subclinical Cardiovascular Changes: A Systematic Review and Meta-Analysis
    Enea Bonci, Claudio Chiesa, Paolo Versacci, Caterina Anania, Lucia Martina Silvestri, Lucia Pacifico · 2015 · BioMed Research International
  50. A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3′UTR
    Mayada Metwally, Ali Bayoumi, Manuel Romero‐Gómez, Khaled Thabet, Miya John, Leon Anton Adams, Xiaoqi Huo, R. Aller, Carmelo García‐Monzón, M. Arias et al. · 2018 · Journal of Hepatology
  51. High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase–Lowering Effect of a HSD17B13 Variant
    Helene Gellert‐Kristensen, Børge Grønne Nordestgaard, Anne Tybjærg‐Hansen, Stefan Stender · 2019 · Hepatology
  52. Genetics of Metabolic Dysfunction-associated Steatotic Liver Disease: The State of the Art Update
    Silvia C. Sookoian, Yaron Rotman, Luca V. C. Valenti · 2024 · Clinical Gastroenterology and Hepatology
  53. Genetic background in nonalcoholic fatty liver disease: A comprehensive review
    Fabio Salvatore Macaluso · 2015 · World Journal of Gastroenterology
  54. Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD)
    Narendra Singh Choudhary, Ajay Kumar. Duseja · 2020 · Translational Gastroenterology and Hepatology
  55. Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease
    Raffaele Galiero, Alfredo Caturano, Erica Vetrano, Arturo Cesaro, Luca Rinaldi, Teresa Salvatore, Raffaele Marfella, Celestino Sardu, Elisabetta Moscarella, Felice Gragnano et al. · 2021 · Reviews in Cardiovascular Medicine
  56. Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease
    Vera H. Fengler, Tanja Macheiner, Sonja M. Kessler, Beate Czepukojc, Katja Gemperlein, Rolf Müller, Alexandra K. Kiemer, Christoph Magnes, Johannes Haybaeck, Carolin Lackner et al. · 2016 · PLoS ONE
  57. β-Klotho gene variation is associated with liver damage in children with NAFLD
    Paola Dongiovanni, Annalisa Crudele, Nadia Panera, Ilaria Romito, Marica Meroni, Cristiano De Stefanis, Alessia Palma, Donatella Comparcola, Anna Ludovica Fracanzani, Luca Miele et al. · 2019 · Journal of Hepatology
  58. Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in humans
    Borén, Jan, Adiels, Martin, Björnson, Elias, Matikainen, Niina, Söderlund, Sanni, Rämö, Joel, Ståhlman, Marcus, Ripatti, Pietari, Ripatti, Samuli, Palotie, Aarno et al. · 2020 · JCI Insight
  59. Paradoxical Dissociation Between Hepatic Fat Content and De Novo Lipogenesis Due to PNPLA3 Sequence Variant
    Rosellina Margherita Mancina, Niina Matikainen, Cristina Maglio, Sanni Söderlund, Nina M I Lundbom, Antti Hakkarainen, Raffaela Rametta, Enrico Mozzi, Silvia Rossana Fargion, Luca V. C. Valenti et al. · 2015 · The Journal of Clinical Endocrinology & Metabolism
  60. Oxidative Stress Management in Chronic Liver Diseases and Hepatocellular Carcinoma
    Daisuke Uchida, Akinobu Takaki, Atsushi Oyama, Takuya Adachi, Nozomu Wada, Hideki Onishi, Hiroyuki Okada · 2020 · Nutrients
  61. Lean NAFLD: an underrecognized and challenging disorder in medicine
    Sheila Maier, Amanda C. Wieland, Melanie Cree‐Green, Kristen J. Nadeau, Shelby A. Sullivan, Miguel Angel Lanaspa, Richard J. Johnson, Thomas Jensen · 2021 · Reviews in Endocrine and Metabolic Disorders
  62. Diagnostic Modalities of Non-Alcoholic Fatty Liver Disease: From Biochemical Biomarkers to Multi-Omics Non-Invasive Approaches
    Eirini Martinou, Marinos Pericleous, Irena Stefanova, Vasha Kaur, Angeliki M. Angelidi · 2022 · Diagnostics
  63. The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing
    Yuxuan Liu, Fazlyn Reeny Abdul Razak, Martijn M. Terpstra, Fong Chun Chan, Ali Saber, Marcel Nijland, Gustaaf Willem Van Imhoff, Lydia Visser, Randy D. Gascoyne, Christian Steidl et al. · 2014 · Leukemia
  64. The intersection of nonalcoholic fatty liver disease and obesity
    Jennifer Woo Baidal, Joel E. Lavine · 2016 · Science Translational Medicine
  65. PNPLA3 p.I148M variant is associated with greater reduction of liver fat content after bariatric surgery
    Marcin Jan Krawczyk, Raúl Jiménez-Agüero, J.M. Alústiza, José Ignacio Emparanza, Maria Jesus Perugorria, Luís Bujanda, Frank Lammert, Jesús M. Bañales · 2016 · Surgery for Obesity and Related Diseases
  66. Hepatic inositol 1,4,5 trisphosphate receptor type 1 mediates fatty liver
    Colleen N. Feriod, A. G. de Oliveira, Mateus T. Guerra, Lily L. Nguyen, Kisha Mitchell Richards, Michael J. Jurczak, Hai‐Bin Ruan, João Paulo Camporez, Xiaoyong Yang, Gerald I. Shulman et al. · 2016 · Hepatology Communications
  67. Prevalence of the TM6SF2 variant and non-alcoholic fatty liver disease in Chinese
    Vincent Wai‐Sun Wong, Grace Lai‐Hung Wong, Chi‐Hang Tse, Henry Lik‐Yuen Chan · 2014 · Journal of Hepatology
  68. Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort
    Julia Kozlitina, Haihong Zhou, Patricia N. Brown, Rory J. Rohm, Yi Pan, Gulesi Ayanoglu, Xiaoyan Du, Eric F. Rimmer, Dermot F. Reilly, Thomas P. Roddy et al. · 2016 · Journal of the American Society of Nephrology
  69. Nonalcoholic fatty liver disease and type 2 diabetes: pathophysiological mechanisms shared between the two faces of the same coin
    Carlo Acierno, Alfredo Caturano, Pia Clara Pafundi, Riccardo Nevola, Luigi Elio Adinolfi, Ferdinando Carlo Sasso · 2020 · Exploration of Medicine
  70. Multi-omics profiling: the way toward precision medicine in metabolic diseases
    Cheng Hu, Weiping Jia · 2021 · Journal of Molecular Cell Biology
  71. Genetic and hormonal control of hepatic steatosis in female and male mice
    Frode Norheim, Simon T. Y. Hui, Emre Külahçıoğlu, Margarete Mehrabian, Rita M. Cantor, Calvin Pan, Brian W. Parks, Aldons Jake Lusis · 2016 · Journal of Lipid Research
  72. Genetics of Nonalcoholic Fatty Liver Disease: From Pathogenesis to Therapeutics
    Silvia C. Sookoian, Carlos Jose Pirola · 2019 · Seminars in Liver Disease
  73. Nonalcoholic fatty liver disease or metabolic dysfunction‐associated fatty liver disease diagnoses and cardiovascular diseases: From epidemiology to drug approaches
    Paola Dongiovanni, Erika Paolini, Alberto Corsini, Cesare Riccardo Sirtori, Massimiliano Ruscica · 2021 · European Journal of Clinical Investigation
  74. Advancing the understanding of NAFLD to hepatocellular carcinoma development: From experimental models to humans
    Kan Chen, Jianbo Ma, Xiaoyuan Jia, Wen Ai, Zhongren Ma, Qiuwei Pan · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  75. The immune landscape in nonalcoholic steatohepatitis
    Narayanan, Sowmya, Surette, Fionna A., Hahn, Young S. · 2016 · Immune Network
  76. Clinical strategy of diagnosing and following patients with nonalcoholic fatty liver disease based on invasive and noninvasive methods
    Masato Yoneda, Kento Imajo, Hirokazu Takahashi, Yuji Ogawa, Yuichiro Eguchi, Yoshio Sumida, Masashi Yoneda, Miwa Kawanaka, Satoru Saito, Katsutoshi Tokushige et al. · 2017 · Journal of Gastroenterology
  77. Genetic Insights for Drug Development in NAFLD
    Mohammed Eslam, Jacob George · 2019 · Trends in Pharmacological Sciences
  78. GutSelf: Interindividual Variability in the Processing of Dietary Compounds by the Human Gastrointestinal Tract
    Barbara Walther, Aaron Mitchell Lett, Alessandra Bordoni, Lidia Tomás‐Cobos, Juan Antonio Nieto, Didier Dupont, Francesca Danesi, Danit Rivka Shahar, Ana Echaniz, Roberta Re et al. · 2019 · Molecular Nutrition & Food Research
  79. Natural History of Simple Steatosis or Nonalcoholic Fatty Liver
    Arka De, Ajay Kumar. Duseja · 2019 · Journal of Clinical and Experimental Hepatology
  80. Pegbelfermin (BMS-986036): an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis
    Cristy R.C. Verzijl, Ivo P. van de Peppel, Dicky Struik, Johan W. Jonker · 2020 · Expert Opinion on Investigational Drugs
  81. Established and emerging factors affecting the progression of nonalcoholic fatty liver disease
    Stergios Kechagias, Patrik Nasr, Julia Blomdahl, Mattias Ekstedt · 2020 · Metabolism
  82. Hepatic Fat—Genetic Risk Score Predicts Hepatocellular Carcinoma in Patients With Cirrhotic HCV Treated With DAAs
    Elisabetta Degasperi, Enrico Galmozzi, Serena Pelusi, Roberta D’Ambrosio, Roberta Soffredini, Marta Borghi, Riccardo Perbellini, F. Facchetti, Massimo Alberto Iavarone, Angelo Sangiovanni et al. · 2020 · Hepatology
  83. Non-Alcoholic Fatty Liver Disease in Obese Youth With Insulin Resistance and Type 2 Diabetes
    Serena Scapaticci, Ebe D’Adamo, Angelika Mohn, Francesco Chiarelli, Cosimo Giannini · 2021 · Frontiers in Endocrinology
  84. Genetics Is of the Essence to Face NAFLD
    Marica Meroni, Miriam Longo, Giada Tria, Paola Dongiovanni · 2021 · Biomedicines
  85. Genetic and epigenetic mechanisms of NASH
    Mohammed Eslam, Jacob George · 2015 · Hepatology International
  86. Type 2 diabetes partitioned polygenic scores associate with disease outcomes in 454,193 individuals across 13 cohorts
    DiCorpo, Daniel, LeClair, Jessica, Cole, Joanne B., Sarnowski, Chloé, Ahmadizar, Fariba, Bielak, Lawrence F., Blokstra, Anneke, Bottinger, Erwin P., Chaker, Layal, Chen, Yii-Der I. et al. · 2022 · Diabetes Care
  87. Glutathione: Pharmacological aspects and implications for clinical use in non-alcoholic fatty liver disease
    Giovanni Santacroce, Antonella Gentile, Simone Soriano, Andrea Novelli, Marco Vincenzo Lenti, Antonio Di Sabatino · 2023 · Frontiers in Medicine
  88. Genome-wide analysis of hepatic lipid content in extreme obesity
    Johanna Kay DiStefano, Christopher B. Kingsley, G. Craig Wood, Xin Chu, George A. Argyropoulos, Christopher D. Still, Stefania Cotta Doné, Christophe Legendre, Waibhav Tembe, Glenn S. Gerhard · 2014 · Acta Diabetologica
  89. Childhood predictors of adult fatty liver. The Cardiovascular Risk in Young Finns Study
    Emmi Suomela, Mervi Oikonen, Niina Pitkänen, Ari Ahola‐Olli, Johanna M. Virtanen, Riitta K Parkkola, Eero V. Jokinen, Tomi P Laitinen, Nina Hutri‐Kähönen, Mika A. P. Kähönen et al. · 2016 · Journal of Hepatology
  90. Host – hepatitis C viral interactions: The role of genetics
    Markus Hermann Heim, Pierre–Yves Bochud, Jacob George · 2016 · Journal of Hepatology
  91. Genetic determinants of steatosis and fibrosis progression in paediatric non‐alcoholic fatty liver disease
    Christian A. Hudert, Silvia Selinski, Birgit D. Rudolph, Hendrik Bläker, Christoph Loddenkemper, Ria Thielhorn, Nikolaus Berndt, Klaus Golka, Cristina Cadenas, Jörg Reinders et al. · 2018 · Liver International
  92. Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology
    Silvia Sookoian, Carlos Jose Pirola · 2020 · Clinical and Molecular Hepatology
  93. Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles
    Martínez‐Arranz, Ibon, Bruzzone, Chiara, Noureddin, Mazen, Gil‐Redondo, Ruben, Mincholé, Itziar, Bizkarguenaga, Maider, Arretxe, Enara, Iruarrizaga‐Lejarreta, Marta, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando et al. · 2022 · Hepatology
  94. Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition
    Long, Tao, Hassan, Abdirahman, Thompson, Bonne M, McDonald, Jeffrey G, Wang, Jiawei, Li, Xiaochun · 2019 · Nature Communications
  95. NAFLD Preclinical Models: More than a Handful, Less of a Concern?
    Yvonne Oligschlaeger, Ronit Shiri‐Sverdlov · 2020 · Biomedicines
  96. Significance of Simple Steatosis: An Update on the Clinical and Molecular Evidence
    Guillermo Daniel Mazzolini, Jan‐Peter Sowa, Catalina Atorrasagasti, Özlem Kücükoglu, Wing‐Kin Syn, Ali E. Canbay · 2020 · Cells
  97. Comparison and development of advanced machine learning tools to predict nonalcoholic fatty liver disease: An extended study
    Yuan-Xing Liu, Xi Liu, Chao Cen, Xin Li, Jimin Liu, Zhaoyan Ming, Songfeng Yu, Xiaofeng Tang, Lin Zhou, Jun Yu et al. · 2021 · Hepatobiliary & pancreatic diseases international
  98. Genetics, diagnostics and therapeutic advances in NAFLD
    Mary Eugenia Rinella, Arun Jayant Sanyal · 2015 · Nature Reviews Gastroenterology & Hepatology
  99. Additive Effects of the Risk Alleles of PNPLA3 and TM6SF2 on Non-alcoholic Fatty Liver Disease (NAFLD) in a Chinese Population
    Xiaoliang Wang, Zhipeng Liu, Kai Wang, Zhaowen Wang, Xing Sun, Lin Zhong, Guilong Deng, Guohe Song, Baining Sun, Zhihai Peng et al. · 2016 · Frontiers in Genetics
  100. Familial coaggregation of MASLD with hepatocellular carcinoma and adverse liver outcomes: nationwide multigenerational cohort study
    Ebrahimi, Fahim, Hagström, Hannes, Sun, Jiangwei, Bergman, David, Shang, Ying, Yang, Wen, Roelstraete, Bjorn, Ludvigsson, Jonas F. · 2023 · Journal of Hepatology