The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors
Open accessAbstract
Neurofibromatosis 1 is a hereditary syndrome characterized by the development of numerous benign neurofibromas, a small subset of which progress to malignant peripheral nerve sheath tumors (MPNSTs). To better understand the genetic basis for MPNSTs, we performed genome-wide or targeted sequencing on 50 cases. Sixteen MPNSTs but none of the neurofibromas tested were found to have somatic mutations in SUZ12, implicating it as having a central role in malignant transformation.
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Cited by
Kim, K. H., & Roberts, C. W. M. (2016) · Nature Medicine · doi:10.1038/nm.4036 · Cited by 1,471
Epigenetic balance of gene expression by Polycomb and COMPASS families
Piunti, A., & Shilatifard, A. (2016) · Science · doi:10.1126/science.aad9780 · Cited by 524
A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor
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Metadata
- Authors
- Zhang, M., Wang, Y., Jones, S., Sausen, M., McMahon, K., Sharma, R., Wang, Q., Belzberg, A. J., Chaichana, K., Gallia, G. L., Gokaslan, Z. L., Riggins, G. J., Wolinksy, J.-P., Wood, L. D., Montgomery, E. A., Hruban, R. H., Kinzler, K. W., Papadopoulos, N., Vogelstein, B., & Bettegowda, C.
- Venue
- Nature Genetics
- Published
- 2014-10-12
- Volume
- 46
- Issue
- 11
- Pages
- 1170-1172
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W1987937498
- Cited by
- 301
- References
- 20
- FWCI
- 14.55
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhang, M., Wang, Y., Jones, S., Sausen, M., McMahon, K., Sharma, R., Wang, Q., Belzberg, A. J., Chaichana, K., Gallia, G. L., Gokaslan, Z. L., Riggins, G. J., Wolinksy, J.-P., Wood, L. D., Montgomery, E. A., Hruban, R. H., Kinzler, K. W., Papadopoulos, N., Vogelstein, B., & Bettegowda, C. (2014). Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors. Nature Genetics. https://doi.org/10.1038/ng.3116
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