The Knockout Mouse Project

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216

The sequence of the human genome

Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909

Positional cloning of the mouse obese gene and its human homologue

Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419

Initial sequencing and comparative analysis of the mouse genome

Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Chen, R. Z., Akbarian, S., Tudor, M., & Jaenisch, R. (2001) · Nature Genetics · doi:10.1038/85906 · Cited by 1,275

Molecular characterization of the mouse agouti locus

Bultman, S. J., Michaud, E. J., & Woychik, R. P. (1992) · Cell · doi:10.1016/s0092-8674(05)80067-4 · Cited by 805

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

Valenzuela, D. M., Murphy, A. J., Frendewey, D. A., Gale, N. W., Economides, A. N., Auerbach, W., Poueymirou, W. T., Adams, N. C., Rojas, J., Yasenchak, J., et al. (2003) · Nature Biotechnology · doi:10.1038/nbt822 · Cited by 583

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

Zambrowicz, B., Friedrich, G. A., Buxton, E. C., Lilleberg, S. L., Person, C., & Sands, A. (1998) · Nature · doi:10.1038/33423 · Cited by 436

Gene-trap mutagenesis: past, present and beyond

Stanford, W. L., Cohn, J. B., & Cordes, S. P. (2001) · Nature Reviews Genetics · doi:10.1038/35093548 · Cited by 391

Dynamic Gene Expression in the Human Cerebral Cortex Distinguishes Children from Adults

Sterner, K. N., Weckle, A. L., Chugani, H. T., Tarca, A. L., Sherwood, C. C., Hof, P. R., Kuzawa, C. W., Boddy, A. M., Abbas, A., Raaum, R. L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037714 · Cited by 35

Identification and Validation of Novel Spinophilin-associated Proteins in Rodent Striatum Using an Enhanced ex Vivo Shotgun Proteomics Approach

Baucum, A. J., Jalan‐Sakrikar, N., Jiao, Y., Gustin, R. M., Carmody, L., Tabb, D. L., Ham, A. L., & Colbran, R. J. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m900387-mcp200 · Cited by 33

Adding Precision Tools to the Plant Biologists' Toolbox with Chemical Genomics

Raikhel, N. V., & Pirrung, M. C. (2005) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.900155 · Cited by 33

Writing biology with mutant mice: The monstrous potential of post genomic life

Davies, G. F. (2011) · Geoforum · doi:10.1016/j.geoforum.2011.03.004 · Cited by 31

A Genocentric Approach to Discovery of Mendelian Disorders

Hansen, A. W., Murugan, M., Li, H., Khayat, M. M., Wang, L., Rosenfeld, J. A., Andrews, B. K., Jhangiani, S. N., Coban‐Akdemir, Z., Sedlazeck, F. J., et al. (2019) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2019.09.027 · Cited by 32

Path to improving the life cycle and quality of genome-scale models of metabolism

Seif, Y., & Palsson, B. Ø. (2021) · Cell Systems · doi:10.1016/j.cels.2021.06.005 · Cited by 26

Tslc1 (Nectin‐Like Molecule‐2) Is Essential for Spermatozoa Motility and Male Fertility

Surace, E. I., Strickland, A. M., Hess, R. A., Gutmann, D. H., & Naughton, C. K. (2006) · Journal of Andrology · doi:10.2164/jandrol.106.000398 · Cited by 32

Dissecting complex traits: the geneticists' ‘Around the world in 80 days’

Darvasi, A. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.05.003 · Cited by 32

Heat Shock Response: Lessons from Mouse Knockouts

Christians, E., & Benjamin, I. J. (2005) · Springer eBooks · doi:10.1007/3-540-29717-0_6 · Cited by 32

Rationally optimized cryopreservation of multiple mouse embryonic stem cell lines: I—Comparative fundamental cryobiology of multiple mouse embryonic stem cell lines and the implications for embryonic stem cell cryopreservation protocols

Benson, C. M. K., Benson, J. D., & Critser, J. K. (2014) · Cryobiology · doi:10.1016/j.cryobiol.2013.12.007 · Cited by 31

Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center

Wakana, S., Suzuki, T., Furuse, T., Kobayashi, K., Miura, I., Kaneda, H., Yamada, I., Motegi, H., Toki, H., Inoue, M., et al. (2009) · EXPERIMENTAL ANIMALS · doi:10.1538/expanim.58.443 · Cited by 31

RNAi in mice: a promising approach to decipher gene functions in vivo

Coumoul, X., & Deng, C. (2005) · Biochimie · doi:10.1016/j.biochi.2005.11.010 · Cited by 31

FELASA guidelines for the production and nomenclature of transgenic rodents

Rülicke, T., Montagutelli, X., Pintado, B., Thon, R., & Hedrich, H.-J. (2007) · Laboratory Animals · doi:10.1258/002367707781282758 · Cited by 30

Mouse-based genetic modeling and analysis of Down syndrome

Xing, Z., Li, Y., Pao, A., Bennett, A. S., Tycko, B., Mobley, W. C., & Yu, Y. E. (2016) · British Medical Bulletin · doi:10.1093/bmb/ldw040 · Cited by 32

Understanding Tendons: Lessons from Transgenic Mouse Models

Cáceres, M. D., Pfeifer, C., & Docheva, D. (2018) · Stem Cells and Development · doi:10.1089/scd.2018.0121 · Cited by 33

Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions

Meng, X., McGraw, C. M., Wang, W., Jing, J., Yeh, S.-Y., Wang, L., Lopez, J., Brown, A. M., Lin, T., Chen, W., et al. (2019) · eLife · doi:10.7554/elife.46773 · Cited by 35

The paintfill method as a tool for analyzing the three-dimensional structure of the inner ear

Kiernan, A. E. (2006) · Brain Research · doi:10.1016/j.brainres.2006.02.037 · Cited by 30

Reconstructing Generalized Logical Networks of Transcriptional Regulation in Mouse Brain from Temporal Gene Expression Data

Song, M. J., Lewis, C. K., Lance, E. R., Chesler, E. J., Yordanova, R., Langston, M. A., Lodowski, K. H., & Bergeson, S. E. (2009) · EURASIP Journal on Bioinformatics and Systems Biology · doi:10.1155/2009/545176 · Cited by 30

Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice

Yu, T., Clapcote, S. J., Li, Z., Liu, C., Pao, A., Bechard, A. R., Carattini-Rivera, S., Matsui, S., Roder, J., Baldini, A., et al. (2010) · Mammalian Genome · doi:10.1007/s00335-010-9262-x · Cited by 29

Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease

Oliver, P. L., Bitoun, E., & Davies, K. E. (2007) · Mammalian Genome · doi:10.1007/s00335-007-9014-8 · Cited by 31

Elephant Transcriptome Provides Insights into the Evolution of Eutherian Placentation

Hou, Z., Sterner, K. N., Romero, R. J., Than, N. G., Grau, J. M. G., Weckle, A. L., Xing, J., Benirschke, K., Goodman, M., & Wildman, D. E. (2012) · Genome Biology and Evolution · doi:10.1093/gbe/evs045 · Cited by 29

Animal models of autoimmune hepatitis

Czaja, A. J. (2010) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.10.42 · Cited by 27

MamPhEA: a web tool for mammalian phenotype enrichment analysis

Weng, M., & Liao, B. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq359 · Cited by 27

Harnessing model organism genomics to underpin the machine learning-based prediction of essential genes in eukaryotes – Biotechnological implications

Campos, T. D. L., Korhonen, P. K., Hofmann, A., Gasser, R. B., & Young, N. D. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107822 · Cited by 28

A Novel Selection Marker for Efficient DNA Cloning and Recombineering in E. coli

Jang, C., & Magnuson, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057075 · Cited by 28

Mouse models for human otitis media

Trune, D. R., & Zheng, Q. Y. (2009) · Brain Research · doi:10.1016/j.brainres.2009.02.047 · Cited by 28

Optimization of Volumetric Computed Tomography for Skeletal Analysis of Model Genetic Organisms

Vasquez, S. X., Hansen, M. S., Bahadur, A. N., Hockin, M. F., Kindlmann, G., Nevell, L., Wu, I. Q., Grunwald, D. J., Weinstein, D. M., Jones, G., et al. (2008) · The Anatomical Record · doi:10.1002/ar.20670 · Cited by 28

VelociMouse: Fully ES Cell-Derived F0-Generation Mice Obtained from the Injection of ES Cells into Eight-Cell-Stage Embryos

DeChiara, T. M., Poueymirou, W. T., Auerbach, W., Frendewey, D. A., Yancopoulos, G. D., & Valenzuela, D. M. (2009) · Methods in molecular biology · doi:10.1007/978-1-59745-471-1_16 · Cited by 28

Developing New Drugs for Schizophrenia: From Animals to the Clinic

Jones, D. N. C., Gartlon, J. E., Minassian, A., Perry, W., & Geyer, M. A. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-373861-5.00008-4 · Cited by 30

Uncovering the uncharacterized and unexpected: Unbiased phenotype‐driven screens in the mouse

Caspary, T., & Anderson, K. V. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20853 · Cited by 28

Obesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivo

Powell, D. R. (2006) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00220.x · Cited by 28

Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes

Rosen, B. P., Schick, J., & Wurst, W. (2015) · Mammalian Genome · doi:10.1007/s00335-015-9598-3 · Cited by 31

Centralized mouse repositories

Donahue, L. R., de Angelis, M. H., Hagn, M., Franklin, C. L., Lloyd, K. C. K., Magnuson, T., McKerlie, C., Nakagata, N., Obata, Y., Read, S., et al. (2012) · Mammalian Genome · doi:10.1007/s00335-012-9420-4 · Cited by 27

Translational geroscience: From invertebrate models to companion animal and human interventions

Lee, M. B., & Kaeberlein, M. R. (2018) · Translational Medicine of Aging · doi:10.1016/j.tma.2018.08.002 · Cited by 28

Engineering Embryonic Stem Cells with Recombinase Systems

Schnütgen, F., Stewart, A. F., von Melchner, H., & Anastassiadis, K. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)20007-7 · Cited by 27

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA

Langerak, P. (2005) · Nucleic Acids Research · doi:10.1093/nar/gni187 · Cited by 27

MaveRegistry: a collaboration platform for multiplexed assays of variant effect

Kuang, D., Weile, J., Kishore, N., Nguyen, M., Rubin, A. F., Fields, S., Fowler, D. M., & Roth, F. P. (2021) · Bioinformatics · doi:10.1093/bioinformatics/btab215 · Cited by 29

Producing Fully ES Cell-Derived Mice from Eight-Cell Stage Embryo Injections

DeChiara, T. M., Poueymirou, W. T., Auerbach, W., Frendewey, D. A., Yancopoulos, G. D., & Valenzuela, D. M. (2010) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(10)76016-x · Cited by 26

Virtues and limitations of the preimplantation mouse embryo as a model system

Taft, R. A. (2007) · Theriogenology · doi:10.1016/j.theriogenology.2007.09.032 · Cited by 29

Laboratory Mouse Models for the Human Genome-Wide Associations

Kitsios, G. D., Tangri, N., Castaldi, P. J., & Ioannidis, J. P. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013782 · Cited by 26

Functional Phenotyping of the Maternal Albumin Turnover in the Mouse Placenta by Dynamic Contrast-Enhanced MRI

Plaks, V., Sapoznik, S., Berkovitz, E., Haffner‐Krausz, R., Dekel, N., Harmelin, A., & Neeman, M. (2010) · Molecular Imaging and Biology · doi:10.1007/s11307-010-0390-1 · Cited by 26

ROSA26Flpo deleter mice promote efficient inversion of conditional gene traps in vivo

Raymond, C. S., & Soriano, P. M. (2010) · genesis · doi:10.1002/dvg.20659 · Cited by 26

Gene Targeting Using Homologous Recombination in Embryonic Stem Cells: The Future for Behavior Genetics?

Gerlai, R. T. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00043 · Cited by 26

Copulatory plugs inhibit the reproductive success of rival males

Mangels, R., Tsung, K., Kwan, K., & Dean, M. D. (2016) · Journal of Evolutionary Biology · doi:10.1111/jeb.12956 · Cited by 30

Efficient gene targeting in mouse zygotes mediated by CRISPR/Cas9-protein

Jung, C., Zhang, J., Trenchard, E., Lloyd, K. C. K., West, D. B., Rosen, B. P., & de Jong, P. J. (2016) · Transgenic Research · doi:10.1007/s11248-016-9998-5 · Cited by 26

Geneticists prepare for deluge of mutant mice

Abbott, A. (2004) · Nature · doi:10.1038/432541a · Cited by 26

Progress towards completing the mutant mouse null resource

Peterson, K. A., & Murray, S. A. (2021) · Mammalian Genome · doi:10.1007/s00335-021-09905-0 · Cited by 25

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans

Yao, Y., Jiang, P. D., Chao, B. N., Cağdaş, D. N., Kubo, S., Balasubramaniyam, A., Zhang, Y., Shadur, B., NaserEddin, A., Folio, L. R., et al. (2022) · The Journal of Experimental Medicine · doi:10.1084/jem.20201405 · Cited by 23

Endocannabinoid Receptors: CNS Localization of the CB1 Cannabinoid Receptor

Katona, I. (2009) · Current topics in behavioral neurosciences · doi:10.1007/978-3-540-88955-7_3 · Cited by 25

Common Polymorphisms in the Age of Research Domain Criteria (RDoC): Integration and Translation

Glatt, C. E., & Lee, F. S. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.12.020 · Cited by 27

Conditional and inducible gene recombineering in the mouse inner ear

Tian, Y., James, S. R., Zuo, J., Fritzsch, B., & Beisel, K. W. (2006) · Brain Research · doi:10.1016/j.brainres.2006.01.040 · Cited by 28

Genome-wide ENU Mutagenesis for the Discovery of Novel Male Fertility Regulators

Jamsai, D., & O’Bryan, M. K. (2010) · Systems Biology in Reproductive Medicine · doi:10.3109/19396361003706424 · Cited by 24

Permissive and restricted virus infection of murine embryonic stem cells

Wash, R., Calabressi, S., Franz, S., Griffiths, S. J., Goulding, D., Tan, E., Wise, H. M., Digard, P., Haas, J., Efstathiou, S., et al. (2012) · Journal of General Virology · doi:10.1099/vir.0.043406-0 · Cited by 24

Dual function of the UNC-45b Chaperone with myosin and GATA4 in cardiac development

Chen, D., Li, S., Singh, R. R., Spinette, S., Sedlmeier, R., & Epstein, H. F. (2012) · Journal of Cell Science · doi:10.1242/jcs.106435 · Cited by 23

Gene Perturbation Atlas (GPA): a single-gene perturbation repository for characterizing functional mechanisms of coding and non-coding genes

Xiao, Y., Gong, Y., Lv, Y., Lan, Y., Hu, J. R., Li, F., Xu, J., Bai, J., Deng, Y., Liu, L., et al. (2015) · Scientific Reports · doi:10.1038/srep10889 · Cited by 26

Complementing complexity

Mackay, T. F. C. (2004) · Nature Genetics · doi:10.1038/ng1104-1145 · Cited by 24

Derivation and transcriptional profiling analysis of pluripotent stem cell lines from rat blastocysts

Li, C., Yang, Y., Gu, J., Ma, Y., & Jin, Y. (2008) · Cell Research · doi:10.1038/cr.2008.301 · Cited by 24

Potential and limitations of genetic manipulation in animals

O'Sullivan, G. J., O’Tuathaigh, C. M. P., Clifford, J. J., O’Meara, G. F., Croke, D. T., & Waddington, J. L. (2006) · Drug Discovery Today Technologies · doi:10.1016/j.ddtec.2006.06.005 · Cited by 22

Identification of aluminium transport-related genes via genome-wide phenotypic screening of Saccharomyces cerevisiae

Tun, N. M., O'Doherty, P. J., Chen, Z., Wu, X., Bailey, T. D., Kersaitis, C., & Wu, M. J. (2014) · Metallomics · doi:10.1039/c4mt00116h · Cited by 23

Arguably big biology: Sociology, spatiality and the knockout mouse project

Davies, G. F. (2013) · BioSocieties · doi:10.1057/biosoc.2013.25 · Cited by 22

Mouse phenogenomics, toolbox for functional annotation of human genome

Kim, I.-Y., Shin, J. H., & Seong, J. K. (2010) · BMB Reports · doi:10.5483/bmbrep.2010.43.2.079 · Cited by 23

Comparative Genomics for Detecting Human Disease Genes

Moreno, C., Lazar, J., Jacob, H. J., & Kwitek, A. E. (2008) · Advances in genetics · doi:10.1016/s0065-2660(07)00423-3 · Cited by 23

Highly effective removal of floxed Blasticidin S resistance cassettes from Dictyostelium discoideum mutants by extrachromosomal expression of Cre

Linkner, J., Nordholz, B., Junemann, A., Winterhoff, M., & Faix, J. (2011) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2011.11.001 · Cited by 22

Genetically Engineered Humanized Mouse Models for Preclinical Antibody Studies

Proetzel, G., Wiles, M. V., & Roopenian, D. C. (2013) · BioDrugs · doi:10.1007/s40259-013-0071-0 · Cited by 22

Genetically engineered mouse models for skin research: Taking the next step

Jiang, C., & Roop, D. R. (2008) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2008.03.012 · Cited by 23

Gene Trapping in Embryonic Stem Cells

Stanford, W. L., Epp, T. A., Reid, T., & Rossant, J. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)20008-9 · Cited by 22

Recent innovations in tissue‐specific gene modifications in the mouse

Furuta, Y., & Behringer, R. R. (2005) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.20036 · Cited by 22

Mouse models as a tool to unravel the genetic basis for human otitis media

Zheng, Q. Y., Hardisty-Hughes, R. E., & Brown, S. D. M. (2006) · Brain Research · doi:10.1016/j.brainres.2006.01.046 · Cited by 22

Phenotypic Characterization of the KK/HlJ Inbred Mouse Strain

Berndt, A., Sundberg, B. A., Silva, K. A., Kennedy, V. E., Richardson, M. A., Li, Q., Bronson, R. T., Uitto, J., & Sundberg, J. P. (2013) · Veterinary Pathology · doi:10.1177/0300985813501335 · Cited by 21

Identification and functional characterization of piwi1 gene in sea cucumber, Apostichopus japonicas

Sun, Z., Wei, J.-L., Cui, Z., Han, Y.-L., Zhang, J., Song, J., & Chang, Y. (2020) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2020.110536 · Cited by 21

Bi-allelic gene targeting in mouse embryonic stem cells

Tate, P. H., & Skarnes, W. C. (2011) · Methods · doi:10.1016/j.ymeth.2010.12.025 · Cited by 21

Development of a gene‐trap vector with a highly sensitive fluorescent protein reporter system for expression profiling

Tanaka, T. S., Davey, R. E., Lan, Q., Zandstra, P. W., & Stanford, W. L. (2008) · genesis · doi:10.1002/dvg.20404 · Cited by 21

Mutagenesis in rodents using the L1 retrotransposon

Ostertag, E. M., Madison, B., & Kano, H. (2007) · Genome biology · doi:10.1186/gb-2007-8-s1-s16 · Cited by 21

Morphological, physiological and behavioural evaluation of a ‘Mice in Space’ housing system

Blottner, D., Serradj, N., Salanova, M., Touma, C., Palme, R., Silva, M., Aerts, J., Berckmans, D., Vico, L., Liu, Y., et al. (2009) · Journal of Comparative Physiology B · doi:10.1007/s00360-008-0330-4 · Cited by 20

Whole-Organism Cellular Pathology

Cheng, K. C., Katz, S. R., Lin, A. Y., Xin, X., & Ding, Y. (2016) · Advances in genetics · doi:10.1016/bs.adgen.2016.05.003 · Cited by 20

Unpackaging the genetics of mammalian fertility: strategies to identify the “reproductive genome”†

Schimenti, J. C., & Handel, M. A. (2018) · Biology of Reproduction · doi:10.1093/biolre/ioy133 · Cited by 20

Systems Biology of Circadian Rhythms: An Outlook

Haro, L. D., & Panda, S. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406294767 · Cited by 20

Two ways to trap a gene in mice

Skarnes, W. C. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506279102 · Cited by 20

An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes

Bao, L., Peirce, J. L., Zhou, M., Li, H., Goldowitz, D., Williams, R. W., Lu, L., & Cui, Y. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm089 · Cited by 20

Non-surgical alternatives to invasive procedures in mice

Marini, J. C., Lee, B., & Garlick, P. J. (2006) · Laboratory Animals · doi:10.1258/002367706777611479 · Cited by 20

EXOSC10/Rrp6 is essential for the eight-cell embryo/morula transition

Petit, F. G., Jamin, S. P., Kernanec, P.-Y., Becker, E., Halet, G., & Primig, M. (2022) · Developmental Biology · doi:10.1016/j.ydbio.2021.12.010 · Cited by 20

REFERENCE VALUES FOR THE HAEMATOLOGY PROFILE OF CONVENTIONAL GRADE OUTBRED ALBINO MICE (Mus musculus) IN NSUKKA, EASTERN NIGERIA

Ihedioha, J. I., Ugwuja, J. I., Noel-Uneke, O. A., Udeani, I. J., & Daniel-Igwe, G. (2016) · Animal Research International · Cited by 19

Cancer gene discovery in mouse and man

Mattison, J., van der Weyden, L., Hubbard, T., & Adams, D. J. (2009) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2009.03.001 · Cited by 21

Comprehensive comparative homeobox gene annotation in human and mouse

Wilming, L. G., Boychenko, V., & Harrow, J. (2015) · Database · doi:10.1093/database/bav091 · Cited by 21

What Have We Learned from Murine Models of Otitis Media?

Tyrer, H. E., Crompton, M., & Bhutta, M. F. (2013) · Current Allergy and Asthma Reports · doi:10.1007/s11882-013-0360-1 · Cited by 19

Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea

Massironi, S. M. G., Reis, B. L. F. S., Carneiro, J. G., Barbosa, L. B. S., Ariza, C. B., Santos, G. C., Guénet, J. L., & Godard, A. L. B. (2006) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2006000900009 · Cited by 19

High-throughput trapping of secretory pathway genes in mouse embryonic stem cells

De-Zolt, S. (2006) · Nucleic Acids Research · doi:10.1093/nar/gnj026 · Cited by 19

Genomics of the future: Identification of quantitative trait loci in the mousePreprint

Flaherty, L. A., Herron, B. J., & Symula, D. J. (2005) · Genome Research · doi:10.1101/gr.3841405 · Cited by 19

Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice

Sheppard, S. E., Bryant, L. M., Wickramasekara, R. N., Vaccaro, C., Robertson, B., Hallgren, J., Hulen, J., Watson, C. J., Faùndes, V., Duffourd, Y., et al. (2023) · Science Advances · doi:10.1126/sciadv.ade1463 · Cited by 20

Targeted mutagenesis tools for modelling psychiatric disorders

Deussing, J. M. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1708-5 · Cited by 20

Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice

Ermakova, O. V., Piszczek, Ł., Luciani, L., Cavalli, F. M. G., Ferreira, T., Farley, D., Rizzo, S., Paolicelli, R. C., Banchaabouchi, M. A., Nerlov, C., et al. (2010) · EMBO Molecular Medicine · doi:10.1002/emmm.201000112 · Cited by 18

Immunity against the Obligate Intracellular Bacterial Pathogen Rickettsia australis Requires a Functional Complement System

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Towards the mammalian interactome: Inference of a core mammalian interaction set in mouse

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