The Knockout Mouse Project

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216

The sequence of the human genome

Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909

Positional cloning of the mouse obese gene and its human homologue

Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419

Initial sequencing and comparative analysis of the mouse genome

Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Chen, R. Z., Akbarian, S., Tudor, M., & Jaenisch, R. (2001) · Nature Genetics · doi:10.1038/85906 · Cited by 1,275

Molecular characterization of the mouse agouti locus

Bultman, S. J., Michaud, E. J., & Woychik, R. P. (1992) · Cell · doi:10.1016/s0092-8674(05)80067-4 · Cited by 805

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

Valenzuela, D. M., Murphy, A. J., Frendewey, D. A., Gale, N. W., Economides, A. N., Auerbach, W., Poueymirou, W. T., Adams, N. C., Rojas, J., Yasenchak, J., et al. (2003) · Nature Biotechnology · doi:10.1038/nbt822 · Cited by 583

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

Zambrowicz, B., Friedrich, G. A., Buxton, E. C., Lilleberg, S. L., Person, C., & Sands, A. (1998) · Nature · doi:10.1038/33423 · Cited by 436

Gene-trap mutagenesis: past, present and beyond

Stanford, W. L., Cohn, J. B., & Cordes, S. P. (2001) · Nature Reviews Genetics · doi:10.1038/35093548 · Cited by 391

Online High-throughput Mutagenesis Designer Using Scoring Matrix of Sequence-specific Endonucleases

Guo, D., Li, X., Zhu, P., Feng, Y., Yang, J., Zheng, Z., Yang, W., Zhang, E., Zhou, S., & Wang, H. (2015) · Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics · doi:10.1515/jib-2015-283 · Cited by 17

CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene

Hirose, M., Hasegawa, A., Mochida, K., Matoba, S., Hatanaka, Y., Inoue, K., Goto, T., Kaneda, H., Yamada, I., Furuse, T., et al. (2017) · Scientific Reports · doi:10.1038/srep42476 · Cited by 17

Production of Mouse Chimeras by Aggregating Pluripotent Stem Cells with Embryos

Nagy, A., Nagy, K. V., & Gertsenstein, M. (2010) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(10)76008-0 · Cited by 17

Power matters in closing the phenotyping gap

Meyer, C. W., Elvert, R., Scherag, A., Ehrhardt, N., Gailus‐Durner, V., Fuchs, H., Schäfer, H., de Angelis, M. H., Heldmaier, G., & Klingenspor, M. (2007) · Die Naturwissenschaften · doi:10.1007/s00114-006-0203-1 · Cited by 17

PIWI-Interacting RNA (piRNA) and Epigenetic Editing in Environmental Health Sciences

Perera, B. P. U., Morgan, R. K., Polemi, K. M., Sala-Hamrick, K. E., Svoboda, L. K., & Dolinoy, D. C. (2022) · Current Environmental Health Reports · doi:10.1007/s40572-022-00372-6 · Cited by 17

Characterization and Validation of Cre‐Driver Mouse Lines

Gofflot, F., Wendling, O., Chartoire, N., Birling, M., Warot, X., & Auwerx, J. H. (2011) · Current Protocols in Mouse Biology · doi:10.1002/9780470942390.mo100103 · Cited by 16

Removing the cloak of invisibility: phenotyping the mouse

Justice, M. J. (2008) · Disease Models & Mechanisms · doi:10.1242/dmm.001057 · Cited by 16

Tissue-specific Spred-2 promoter activity characterized by a gene trap approach

Bundschu, K., Gattenlöhner, S., Knobeloch, K., Walter, U., & Schuh, K. (2005) · Gene Expression Patterns · doi:10.1016/j.modgep.2005.08.003 · Cited by 16

Large-scale, saturating insertional mutagenesis of the mouse genome

Gragerov, A., Horie, K., Pavlova, M. N., Madisen, L., Zeng, H., Gragerova, G., Rhode, A., Dolka, I., Roth, P., Ebbert, A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700608104 · Cited by 16

Cardiac Development: New concepts

Gruber, P. J. (2005) · Clinics in Perinatology · doi:10.1016/j.clp.2005.09.003 · Cited by 16

Finding the molecular basis of complex genetic variation in humans and mice

Mott, R. (2006) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2005.1798 · Cited by 16

MAGED1:Molecular insights and clinical implications

Wang, X., Gao, X., & Xu, Y. (2011) · Annals of Medicine · doi:10.3109/07853890.2011.573806 · Cited by 15

Genetically modified mice—successes and failures of a widely used technology

Castrop, H. (2010) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-009-0770-z · Cited by 15

Phenotyping cardiac and structural birth defects in fetal and newborn mice

Liu, X., Kim, A. J., Reynolds, W., Wu, Y. L., & Lo, C. W. Y. (2017) · Birth Defects Research · doi:10.1002/bdr2.1048 · Cited by 15

AMP Deaminase 3 Deficiency Enhanced 5′-AMP Induction of Hypometabolism

Daniels, I. S., O’Brien, W. G., Nath, V., Zhao, Z., & Lee, C. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075418 · Cited by 15

Differences in bone structure and unloading-induced bone loss between C57BL/6N and C57BL/6J mice

Sankaran, J. S., Varshney, M., & Judex, S. (2017) · Mammalian Genome · doi:10.1007/s00335-017-9717-4 · Cited by 15

Engineering mutations: Deconstructing the mouse gene by gene

Raymond, C. S., & Soriano, P. M. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20845 · Cited by 15

PHENOSITE: A WEB DATABASE INTEGRATING THE MOUSE PHENOTYPING PLATFORM AND THE EXPERIMENTAL PROCEDURES IN MICE

Masuya, H., Yoshikawa, S., Heida, N., Toyoda, T., Wakana, S., & Shiroishi, T. (2007) · Journal of Bioinformatics and Computational Biology · doi:10.1142/s0219720007003168 · Cited by 15

Differential effects by sex with Kmt5b loss

Wickramasekara, R. N., Robertson, B., Hulen, J., Hallgren, J., & Stessman, H. A. F. (2021) · Autism Research · doi:10.1002/aur.2516 · Cited by 15

SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model

Morell, M. H., Varela, N., Castillejo-López, C., Coppard, C., Luque, M. J., Wu, Y.-Y., Martín‐Morales, N., Pérez‐Cózar, F., Hernández, G. G., Kumar, R., et al. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2021.103808 · Cited by 16

Genetically modified mice as a tool for the study of human diseases

Bruter, A. V., Varlamova, E. A., Okulova, Y. D., Tatarskiy, V. V., Silaeva, Y. Y., & Filatov, M. A. (2024) · Molecular Biology Reports · doi:10.1007/s11033-023-09066-0 · Cited by 14

High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis

Gao, X.-L., Tian, W., Liu, B., Wu, J., Xie, W., & Shen, Q. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.010616 · Cited by 14

Mouse mutagenesis and phenotyping to generate models of development and disease

Gridley, T., & Murray, S. A. (2022) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2022.02.012 · Cited by 14

Rationally optimized cryopreservation of multiple mouse embryonic stem cell lines: II—Mathematical prediction and experimental validation of optimal cryopreservation protocols

Benson, C. M. K., Benson, J. D., & Critser, J. K. (2014) · Cryobiology · doi:10.1016/j.cryobiol.2013.12.003 · Cited by 14

Generation of Ugt1-Deficient Murine Liver Cell Lines Using TALEN Technology

Porro, F., Bočkor, L., Caneva, A. D., Bortolussi, G., & Muro, A. F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104816 · Cited by 14

Close to the edge: co-authorship proximity of Nobel laureates in Physiology or Medicine, 1991–2010, to cross-disciplinary brokers

Fields, C. (2015) · Scientometrics · doi:10.1007/s11192-015-1526-5 · Cited by 13

Spred2 expression during mouse development

Tuduce, I. L., Schuh, K., & Bundschu, K. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22432 · Cited by 14

Identification of four genes required for mammalian blastocyst formation

Maserati, M. P., Dai, X., Walentuk, M., & Mager, J. (2012) · Zygote · doi:10.1017/s0967199412000561 · Cited by 14

The Perfect Host: A Mouse Host Embryo Facilitating More Efficient Germ Line Transmission of Genetically Modified Embryonic Stem Cells

Taft, R. A., Low, B. E., Byers, S. L., Murray, S. A., Kutny, P. M., & Wiles, M. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067826 · Cited by 13

Embryonic Stem Cells: The Mouse Source—Vehicle for Mammalian Genetics and Beyond (Nobel Lecture)

Evans, M. J. (2008) · ChemBioChem · doi:10.1002/cbic.200800352 · Cited by 13

Integration of Double-Fluorescence Expression Vectors into Zebrafish Genome for the Selection of Site-Directed Knockout/Knockin

Wu, Y., Zhang, G., Xiong, Q., Luo, F., Cui, C., Hu, W., Yu, Y., Su, J., Xu, A., & Zhu, Z. (2006) · Marine Biotechnology · doi:10.1007/s10126-006-5116-7 · Cited by 13

Comparison of PCR-based mutation detection methods and application for identification of mouseSult1a1 mutant embryonic stem cell clones using pooled templates

Greber, B., Tandara, H., Lehrach, H. R., & Himmelbauer, H. (2005) · Human Mutation · doi:10.1002/humu.20168 · Cited by 13

Behavioral Genetic Studies in Rats

Ren, Y., & Palmer, A. A. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9581-3_16 · Cited by 12

Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease

Jokela, H., Hakkarainen, J., Kätkänaho, L., Pakarinen, P., Ruohonen, S. T., Tena‐Sempere, M., Zhang, F., & POUTANEN, M. H. (2017) · Scientific Reports · doi:10.1038/s41598-017-16618-5 · Cited by 11

Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model

Weatherly, S. M., Collin, G. B., Charette, J. R., Stone, L. V., Damkham, N., Hyde, L. F., Peterson, J. G., Hicks, W. L., Carter, G. W., Naggert, J. Κ., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1009798 · Cited by 13

Now and future of mouse mutagenesis for human disease models

Gondo, Y. (2010) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/s1673-8527(09)60076-x · Cited by 12

Leukotriene B4 Receptor 2 Is Critical for the Synthesis of Vascular Endothelial Growth Factor in Allergen-Stimulated Mast Cells

Lee, A., Ro, M., & Kim, J. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502565 · Cited by 12

Reprint of “Abstraction for data integration: Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction”

Rouillard, A. D., Wang, Z., & Ma’ayan, A. (2015) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2015.08.005 · Cited by 12

An impending crisis in the provision of histopathology expertise for mouse functional genomics

Warren, M. V., Studley, M., Dubus, P. R., Fiette, L., Rozell, B., Quintanilla‐Martínez, L., Raspa, M., Breuer, M. L., Song, J., Gates, H., et al. (2008) · The Journal of Pathology · doi:10.1002/path.2460 · Cited by 12

Murine infection models for vaccine development

Matuschewski, K. (2013) · Human Vaccines & Immunotherapeutics · doi:10.4161/hv.23218 · Cited by 12

Mouse Models in Bone Marrow Transplantation and Adoptive Cellular Therapy

Arber, C., Brenner, M. K., & Reddy, P. R. (2013) · Seminars in Hematology · doi:10.1053/j.seminhematol.2013.03.026 · Cited by 12

ADAMTS7 promotes smooth muscle foam cell expansion in atherosclerosis

Chung, A. Y., Fries, L. E., Chang, H.-K., Pan, H., Bashore, A. C., Shuck, K., Matias, C. V., Pardo, J. G., Kesner, J. S., Yan, H., et al. (2026) · Journal of Clinical Investigation · doi:10.1172/jci187451 · Cited by 11

Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes via the PTEN/AKT Signaling Pathway

Kilari, S., Cossette, S. M., Pooya, S., Bordas, M. L., Huang, Y., Ramchandran, R., & Wilkinson, G. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144185 · Cited by 12

Sustaining large-scale infrastructure to promote pre-competitive biomedical research: lessons from mouse genomics

Mishra, A. V., Schofield, P. N., & Bubela, T. M. (2015) · New Biotechnology · doi:10.1016/j.nbt.2015.10.002 · Cited by 11

Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects

Barefield, D. Y., Yamakawa, S., Tahtah, I., Sell, J. J., Broman, M., Laforest, B., Harris, S. I., Álvarez-Arce, A., Araujo, K., Puckelwartz, M. J., et al. (2022) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2022.04.012 · Cited by 11

A Method to Automatic Create Dataset for Training Object Detection Neural Networks

Zhou, S. S., Yang, Z., Zhu, M., Li, H. L., Serikawa, S., Mizumachi, M., & Zhang, L. (2022) · IEEE Access · doi:10.1109/access.2022.3195490 · Cited by 11

Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived cultures

Ahmed, M. E., Muffat, J., & Li, Y. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1158373 · Cited by 12

Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases

Han, S. K., Kim, I., Hwang, J., & Kim, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136300 · Cited by 11

Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells

Mayasari, N. I., Mukougawa, K., Shigeoka, T., Kawakami, K., Kawaichi, M., & Ishida, Y. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks262 · Cited by 12

Chimeric Mouse Generation by ES Cell Blastocyst Microinjection and Uterine Transfer

Du, Y., Xie, W., Zhang, F., & Liu, C. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8831-0_6 · Cited by 11

Principles for the organization of gene-sets

Li, W., Freudenberg, J., & Oswald, M. (2015) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2015.04.005 · Cited by 12

The retinal phenotype of Grk1-/- is compromised by a Crb1 rd8 mutation.

Pak, J. S., Lee, E.-J., & Craft, C. M. (2015) · Europe PMC (PubMed Central) · Cited by 10

Modeling Insertional Mutagenesis Using Gene Length and Expression in Murine Embryonic Stem Cells

Nord, A. S., VRANIZAN, K. M., Tingley, W. G., Zambon, A. C., Hanspers, K., Fong, L. G., Hu, Y., Bacchetti, P., Ferrin, T. E., Babbitt, P. C., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000617 · Cited by 11

Overview of Drug Polypharmacology and Multitargeted Molecular Design

Chaudhari, R., Tan, Z., & Zhang, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.12323-6 · Cited by 11

Mutagenesis of diploid mammalian genes by gene entrapment

Lin, Q., Donahue, S. L., Moore-Jarrett, T., Cao, S., Osipovich, A. B., & Ruley, H. E. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl728 · Cited by 10

Generation of C57BL/6 Knockout Mice Using C3H × BALB/c Blastocysts

Pacholczyk, G. A., Suhag, R., Mazurek, M., Dederscheck, S. M., & Koni, P. A. (2008) · BioTechniques · doi:10.2144/000112706 · Cited by 10

Report of the 2006 RSPCA/UFAW Rodent Welfare Group meeting

Reed, B., Hawkins, P., Latham, N., Westwood, K., van Driel, K., Battram, C., Golledge, H., Farmer, A.-M., Osborne, N., Jennings, M., et al. (2008) · Lab Animal · doi:10.1038/laban0508-216 · Cited by 10

Mouse Mutagenesis and Disease Models for Neuropsychiatric Disorders

Gondo, Y., Murata, T., Makino, S., Fukumura, R., & Ishitsuka, Y. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_106 · Cited by 11

Working with Miraculous Mice: Mus musculus as a Model Organism

Standley, A., Xie, J., Lau, A. W. Y., Grote, L., & Gifford, A. J. (2024) · Current Protocols · doi:10.1002/cpz1.70021 · Cited by 16

Unlocking the role of transcription activator-like effector nuclease (TALENs) and zinc finger nuclease (ZFN) in the treatment of HIV

Zubair, A., Ali, M., Ahmad, F., & Althobaiti, S. A. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10993-3 · Cited by 10

Essential steps in super user education for ambulatory clinic nurses.

McIntire, S., & Clark, T. M. (2009) · PubMed · Cited by 9

Multiscale Characterization of the PEPCK‐Cmus Mouse through 3D Cryoimaging

Roy, D., Gargesha, M., Steyer, G. J., Hakimi, P., Hanson, R. W., & Wilson, D. L. (2010) · International Journal of Biomedical Imaging · doi:10.1155/2010/105984 · Cited by 9

BioMart as an integration solution for the International Knockout Mouse Consortium

Oakley, D., Iyer, V., Skarnes, W. C., & Smedley, D. P. (2011) · Database · doi:10.1093/database/bar028 · Cited by 8

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology

García‐Tuñón, I., Vuelta, E., Lozano, L., Herrero, M., Méndez, L., Palomero-Hernandez, J., Pérez-Caro, M., Pérez-García, J., González‐Sarmiento, R., & Sánchez‐Martín, M. (2019) · Molecular Biology Reports · doi:10.1007/s11033-019-05214-7 · Cited by 9

The Problem with Academic Medicine: Engineering Our Way into and out of the Mess

Rees, J. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020111 · Cited by 9

Using Mouse Genomics to Understand Idiopathic Interstitial Fibrosis

Brass, D. M., Tomfohr, J. K., Yang, I. V., & Schwartz, D. A. (2007) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200607-147jg · Cited by 9

Transgenic and Gene Replacement Models of Epilepsy: Targeting Ion Channel and Neurotransmission Pathways in Mice

Burgess, D. L. (2006) · Elsevier eBooks · doi:10.1016/b978-012088554-1/50018-9 · Cited by 9

The gene trap resource: A treasure trove for hemopoiesis research

Forrai, A., & Robb, L. (2005) · Experimental Hematology · doi:10.1016/j.exphem.2005.03.016 · Cited by 9

Capturing benefits from the bovine genome sequence

Tellam, R. L. (2007) · Australian Journal of Experimental Agriculture · doi:10.1071/ea06032 · Cited by 9

Mouse liaison for integrative brain research

Aiba, A., Inokuchi, K., Ishida, Y., Itohara, S., Kobayashi, K., Masu, M., Mishina, M., Miyakawa, T., Mori, H., Nakao, K., et al. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.02.012 · Cited by 9

Genetic and Molecular Quality Control of Genetically Engineered Mice

Lintott, L. G., & Nutter, L. M. J. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2990-1_3 · Cited by 8

Where's the Mouse Info?

Sundberg, J. P., Ward, J. M., & Schofield, P. (2009) · Veterinary Pathology · doi:10.1354/vp.09-vp-0042-s-com · Cited by 8

Closing in on complex traits

Darvasi, A. (2006) · Nature Genetics · doi:10.1038/ng0806-861 · Cited by 8

Mouse mutants and phenotypes: Accessing information for the study of mammalian gene function

Ringwald, M., & Eppig, J. T. (2010) · Methods · doi:10.1016/j.ymeth.2010.12.024 · Cited by 8

Modeling Cancer Using Genetically Engineered Mice

Stiedl, P., Grabner, B., Zboray, K., Bogner, E., & Casanova, E. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2297-0_1 · Cited by 8

Ontology-based validation and identification of regulatory phenotypes

Kulmanov, M., Schofield, P. N., Gkoutos, G. V., & Hoehndorf, R. (2018) · Bioinformatics · doi:10.1093/bioinformatics/bty605 · Cited by 9

Using “-omics” Data to Inform Genome-wide Association Studies (GWASs) in the Osteoporosis Field

Abood, A., & Farber, C. R. (2021) · Current Osteoporosis Reports · doi:10.1007/s11914-021-00684-w · Cited by 8

Applications of comparative evolution to human disease genetics

McWhite, C. D., Liebeskind, B. J., & Marcotte, E. M. (2015) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2015.08.004 · Cited by 8

Laser surgery for mouse geneticists

Gridley, T., & Woychik, R. P. (2007) · Nature Biotechnology · doi:10.1038/nbt0107-59 · Cited by 8

Generation of multipurpose alleles for the functional analysis of the mouse genome

Schnütgen, F. (2006) · Briefings in Functional Genomics and Proteomics · doi:10.1093/bfgp/ell009 · Cited by 8

Welfare assessment and phenotype characterisation of transgenic mice.

Mertens, C., & Rülicke, T. (2007) · PubMed · Cited by 8

Have I been here before? Complex interactions of age and test experience modulate the results of behavioural tests

von Kortzfleisch, V. T., Kästner, N., Prange, L., Kaiser, S., Sachser, N., & Richter, S. H. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.03.042 · Cited by 8

Hypoglossal Nerve Abnormalities as Biomarkers for Central Nervous System Defects in Mouse Lines Producing Embryonically Lethal Offspring

Reissig, L. F., Moghaddam, A. S., Prin, F., Wilson, R. J., Galli, A., Tudor, C. L., White, J. K., Geyer, S. H., Mohun, T. J., & Weninger, W. J. (2021) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2021.625716 · Cited by 8

Uses of Forward and Reverse Genetics in Mice to Study Gene Function

Argmann, C., Dierich, A., & Auwerx, J. H. (2006) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb29a01s73 · Cited by 8

Functional Genomics Requires Ecology

Carroll, L. S., & Potts, W. K. (2006) · Advances in the study of behavior · doi:10.1016/s0065-3454(06)36004-4 · Cited by 8

Mouse Sperm Cryopreservation and Effective Embryo Production Using Cryopreserved C57BL/6 Mouse Sperm

Takeo, T., & Nakagata, N. (2010) · Journal of Mammalian Ova Research · doi:10.1274/jmor.27.70 · Cited by 8

Robust Mouse Tracking in Complex Environments using Neural NetworksPreprint

Geuther, B. Q., Deats, S., Fox, K. J., Murray, S. A., Braun, R. E., White, J. K., Chesler, E. J., Lutz, C. M., & Kumar, V. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/336685 · Cited by 8

Commentary: The International Mouse Phenotyping Consortium: high-throughput in vivo functional annotation of the mammalian genome

Lloyd, K. C. K. (2024) · Mammalian Genome · doi:10.1007/s00335-024-10068-x · Cited by 7

Lack of accelerated ovarian aging in a follicle-stimulating hormone receptor haploinsufficiency model

Mehalko, K., Kim, M., Paye, S., Koh, K., Lu, R. J., & Benayoun, B. A. (2023) · Translational Medicine of Aging · doi:10.1016/j.tma.2023.01.001 · Cited by 7

Redefining ‘stress resistance genes’, and why it matters

Maron, L. G., Piñeros, M. A., Kochian, L. V., & McCouch, S. R. (2016) · Journal of Experimental Botany · doi:10.1093/jxb/erw323 · Cited by 7

Genome wide conditional mouse knockout resources

Kaloff, C., Anastassiadis, K., Ayadi, A., Baldock, R., Beig, J., Birling, M., Bradley, A., Brown, S. D. M., Bürger, A., Bushell, W., et al. (2016) · Drug Discovery Today Disease Models · doi:10.1016/j.ddmod.2017.08.002 · Cited by 7

From Reductionism Toward Integration: Understanding How Social Behavior Emerges From Integrated Circuits

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