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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

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Lymphocyte Homing and Homeostasis

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The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

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Analysis of IL-22 and Th22 Cells by Flow Cytometry in Systemic Lupus Erythematosus

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Immune Biomarkers in Blood from Sarcoma Patients: A Pilot Study

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Differential induction of total IgE by two Salmonella enterica serotypes

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Birch Pollen-Related Food Allergy: An Excellent Disease Model to Understand the Relevance of Immunological Cross-Reactivity for Allergy

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Existe-t-il dans la peau une nouvelle population lymphocytaire Th22 distincte des lymphocytes Th17 ?

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Role of CD4+ T-cells in the pathology of non-alcoholic fatty liver disease and related diseases

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Cytokines and Inflammatory Bowel Disease

de Zoeten, E. F., & Fuss, I. J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5061-0_3 · Cited by 6

Serum level of interleukin-22 in patients with psoriasis and its correlation with disease severity

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Interleukin‐22‐producing T cells: a specialized population involved in skin inflammation?

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Modulation of CD4+ T Helper Cell Memory Responses in the Human Skin

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T-Helper 22 Cell Type Responses to Nickel in Contact Allergic Subjects Are Associated with T-Helper 1, T-Helper 2, and T-Helper 17 Cell Cytokine Profile Responses and Patch Test Reactivity

Masjedi, K., Bruze, M., & Ahlborg, N. (2023) · International Archives of Allergy and Immunology · doi:10.1159/000530105 · Cited by 5

Ustekinumab for the treatment of psoriatic arthritis

Chandler, D. J., & Bewley, A. (2014) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2014.888310 · Cited by 5

New T-Helper Subsets Controlling the Immune System and Tissue Cells

Schmidt‐Weber, C. B. (2010) · Immunotherapy · doi:10.2217/imt.10.35 · Cited by 5

Peripheral blood T helper cell subsets in Löfgren’s and non-Löfgren’s syndrome patients

Kudryavtsev, I. V., Лазарева, Н. М., Baranova, O., Серебрякова, М. К., Сесь, Т. П., Ilkovich, M. M., & Тотолян, А. А. (2022) · Medical Immunology (Russia) · doi:10.15789/1563-0625-pbt-2468 · Cited by 5

CD1a and bound lipids drive T‐cell responses in human skin disease

Ogg, G. S., Rossjohn, J., Clark, R. A., & Moody, D. B. (2023) · European Journal of Immunology · doi:10.1002/eji.202250333 · Cited by 5

Nicotine promotes pathogenic bacterial growth and biofilm formation in peri-implant

Hu, R., Qian, H., Wang, X., Peng, B., & Huang, D. (2024) · Journal of Medical Microbiology · doi:10.1099/jmm.0.001897 · Cited by 5

On the Role of Co-inhibitory Molecules in Dendritic Cell: T Helper Cell Coculture Assays Aimed to Detect Chemical-Induced Contact Allergy

Peiser, M., Hitzler, M., & Luch, A. (2013) · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions · doi:10.1007/978-3-0348-0726-5_9 · Cited by 5

The atopic skin‐like microenvironment modulates the T ‐cell‐polarising cytokine production of myeloid dendritic cells, as determined by laser scanning cytometry

Nagy, G., Doan‐Xuan, Q., Gáspár, K., Mócsai, G., Kapitány, A., Törőcsik, D., Bacsó, Z., Gyimesi, E., Remenyik, É., Bı́ró, T., et al. (2014) · Experimental Dermatology · doi:10.1111/exd.12342 · Cited by 5

Role of Th17 cells in the pathogenesis of rheumatoid arthritis

Boniface, K. (2013) · World Journal of Rheumatology · doi:10.5499/wjr.v3.i3.25 · Cited by 5

Down-regulating cyclin-dependent kinase 9 of alloreactive CD4+ T cells prolongs allograft survival

Zhan, Y., Han, Y., Sun, H., Liang, T. B., Zhang, C., Song, J., & Hou, G. (2016) · Oncotarget · doi:10.18632/oncotarget.8804 · Cited by 5

Differential effects of HIV transmission from monocyte-derived dendritic cells vs. monocytes to IL-17+CD4+ T cells

Mitsuki, Y.-Y., Tuen, M., & Hioe, C. E. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.4a0516-216r · Cited by 5

Diagnostic accuracy of interleukin-22 and adenosine deaminase for tuberculous pleural effusions

He, J., Zhang, R., Shen, Y., Wan, C., Zeng, N., Qin, J., Tian, P., & Chen, L. (2018) · Current Research in Translational Medicine · doi:10.1016/j.retram.2018.08.002 · Cited by 5

Kimura's disease associated with IgA nephropathy: A case report

Zhang, W., Ancharaz, P., & Liu, C. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.7103 · Cited by 5

Detection of Antigen-Specific T Cell Lineages and Effector Functions Based on Secretory Signature

Kirchenbaum, G. A., Hanson, J., Roen, D. R., & Lehmann, P. (2019) · Journal of Immunological Sciences · doi:10.29245/2578-3009/2019/2.1168 · Cited by 4

Diversity of T Helper and Regulatory T Cells and Their Contribution to the Pathogenesis of Allergic Diseases

Ohnmacht, C., & Eyerich, S. (2021) · Handbook of experimental pharmacology · doi:10.1007/164_2021_486 · Cited by 5

Avoiding contact allergens: from basic research to the in vitro identification of contact allergens

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Mechanisms Controlling Hematopoiesis

Fiedler, K., & Brunner, C. (2012) · InTech eBooks · doi:10.5772/33749 · Cited by 10

Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response

Bülow, S., Ederer, K. U., Holzinger, J. M., Zeller, L., Werner, M., Toelge, M., Pfab, C., Hirsch, S., Göpferich, F., Hiergeist, A., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113929 · Cited by 5

Research progress on Th22 cells and related cytokines in tumors: current status and future perspectives.

Wang, Z.-N., Xu, T., & Liu, K. (2023) · PubMed Central · Cited by 4

Transforming growth factor‐β, Interleukin‐23 and interleukin‐1β modulate TH22 response during active multidrug‐resistant tuberculosis

Imperiale, B. R., Gamberale, A., Yokobori, N. K., Garcı́a, A. M., Bartoletti, B., Aidar, O., López, B., Cruz, V. E. M., Montaner, P. G., Palmero, D., et al. (2023) · Immunology · doi:10.1111/imm.13698 · Cited by 4

CD70-induced differentiation of proinflammatory Th1/17/22/GM lymphocytes associated with disease progression and immune reconstitution during HIV infection

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Maternal consumption of a high-fat diet modulates the inflammatory response in their offspring, mediated by the M1 muscarinic receptor

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Nigella sativa monophosphoryl lipid A nanoliposome: a promising antibiotic alternative and immunomodulator to control virulent pandemic drug-resistant Salmonella pullorum infection in broiler chicks

Ahmad, A. A. M., Hussein, E. A. M., Elian, A. A. A. M., Abdelmoneim, M., Ali, A., Abdelhamid, A. E.-S., & Elmowalid, G. A. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-04473-w · Cited by 4

T-cell subsets in scleroderma patients

Truchetet, M., Brembilla, N. C., Montanari, E., & Chizzolini, C. (2010) · Expert Review of Dermatology · doi:10.1586/edm.10.33 · Cited by 4

IL-22 expression is increased variedly in the initial phase, onset and chronic phase of a pristane-induced arthritis rat model

Hou, W., Wang, B., Zhou, Y., Xu, K., Meng, L., Zhu, W., Jiang, C., Xu, P., & Lu, S. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.6739 · Cited by 4

Plasma interleukin-22 level, variants in interleukin-22 gene polymorphism, and the severity of systemic lupus erythematosus among Egyptian pediatric and adolescents

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Lymphoid Hematopoiesis and Lymphocytes Differentiation and Maturation

Marti, L. C., Bacal, N. S., Bento, L. C., Correia, R. P., & Rocha, F. A. (2017) · InTech eBooks · doi:10.5772/intechopen.69058 · Cited by 4

Increased Expression of Aryl Hydrocarbon Receptor in Peripheral Blood Mononuclear Cells of Patients with Autoimmune Hepatitis

Behfarjam, F., & Jadali, Z. (2018) · Middle East Journal of Digestive Diseases · doi:10.15171/mejdd.2018.98 · Cited by 4

Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescencePreprint

Sopena-Rios, M., Ripoll-Cladellas, A., Omidi, F., Ballouz, S., Alquicira-Hernández, J., Oelen, R., Franke, L., van der Wijst, M. G. P., Powell, J. E., & Melé, M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.06.622096 · Cited by 4

Autoimmune hemolytic anemia: the current state of the issue

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Effect of the intestinal microbiota on TH17 cell-derived cytokines in the context of intestinal inflammation

Neuendorff, J., Huber, S., & Pelczar, P. (2026) · Seminars in Immunopathology · doi:10.1007/s00281-026-01070-3 · Cited by 3

Qi Jing Mingmu decoction inhibits the p38 signaling pathway in conjunctivochalasis fibroblasts by down-regulation of Th17 cell differentiation

Ma, K., Liu, J., Sha, Y., Zhang, W., Ni, Z., Kong, X., & Xiang, M. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115812 · Cited by 3

Unique Characteristics of Neonatal T Cells

Kempis-Calanis, L. A., Rodríguez-Jorge, O., Ventura-Martínez, C. J., Gutiérrez‐Reyna, D. Y., Spicuglia, S., & Santana, M. A. (2023) · Medical Research Archives · doi:10.18103/mra.v11i1.3568 · Cited by 3

Chemokines Signature and T Cell Dynamics in Leishmaniasis: Molecular Insight and Therapeutic Application

Upadhyay, S., Kumar, S. B., Singh, V. K., Tiwari, R., Kumar, A., Sundar, S., & Kumar, R. (2024) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2024.36 · Cited by 4

Interleukin 17-producing C-C motif chemokine receptor 6 + conventional CD4+ T cells are arthritogenic in an animal model of spondyloarthritis

Beaufrère, M., Jacoutot, M., Said‐Nahal, R., Cosentino, G., Hutteau-Hamel, T., Clavel, G., Jobart‐Malfait, A., Araujo, L. M. M., Bréban, M., & Glatigny, S. (2025) · Journal of Autoimmunity · doi:10.1016/j.jaut.2025.103413 · Cited by 3

Anti‐tumor necrosis factor treatment increases both the Th17 and Th22 T helper subsets in spondyloarthritis

Andersen, T., Østgård, R., Aspari, M., Kragstrup, T. W., Glerup, H., Jurik, A. G., Johansen, C., Hvid, M., & Deleuran, B. W. (2019) · Apmis · doi:10.1111/apm.12994 · Cited by 3

Role of Lymphocytes in Cancer Immunity and Immune Evasion Mechanisms

Kushekhar, K., Chellappa, S., Aandahl, E. M., & Taskén, K. (2022) · Springer eBooks · doi:10.1007/978-3-030-98950-7_10 · Cited by 6

Th22 is the effector cell of thymosin β15-induced hair regeneration in mice

Tao, N., Ying, Y., Xu, X., Sun, Q., Shu, Y., Hu, S., Lou, Z., & Gao, J. (2024) · Inflammation and Regeneration · doi:10.1186/s41232-023-00316-z · Cited by 3

Characterization of IL ‐22 and IL ‐17 Expressing Leukocytes in the Cervix

Makinde, H. M., Lurain, N. S., Bitterman, P., Martinson, J., Plants, J., LANDAY, A. L., & Spear, G. T. (2015) · American Journal of Reproductive Immunology · doi:10.1111/aji.12435 · Cited by 3

Psoriasis as a Chess Board — An Update of Psoriasis Pathophysiology

Robyn, S., Mitra, A., Morrisey, L., & Lim, H. (2013) · InTech eBooks · doi:10.5772/53580 · Cited by 3

Contribution of IL-22 to Experimental Skin Inflammation

Lecron, J., Paris, I., Bernard, F., & Morel, F. (2012) · Springer eBooks · doi:10.1007/978-3-0348-0522-3_22 · Cited by 3

An Overview of T Cell Subsets and Their Potential Use as Markers of Immunological Ageing

Purnama, C., Camous, X., & Larbi, A. (2013) · Cited by 3

Expression of interleukin-22 and its significance in the pathogenesis of chronic rhinosinusitis.

Wang, X., Gao, M., Xu, Y., Guo, H., & Zhao, C. (2014) · PubMed Central · Cited by 3

T-cell Responses Involved in the Predisposition to Periodontal Disease: Lessons from Immunogenetic Studies of Leprosy

Ohyama, H., & Yamada, N. (2011) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.s1-005 · Cited by 3

Components of the Immune System

Sun, H., Sun, R., & Tian, Z. (2016) · Springer eBooks · doi:10.1007/978-94-024-0902-4_1 · Cited by 4

Cytokines and Chemokines

Turner, M. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-29785-9_15 · Cited by 5

Pathogenesis of Autoimmune Diseases

Röcken, M., & Biedermann, T. (2011) · Springer eBooks · doi:10.1007/978-3-211-99225-8_1 · Cited by 3

Crosstalk between T Helper Cell Subsets and Their Roles in Immunopathogenesis and Outcome of Polytrauma Patients

Sagar, S., Bhardwaj, N., Khurana, S., Mathur, P., & Pal, R. (2020) · Indian Journal of Critical Care Medicine · doi:10.5005/jp-journals-10071-23577 · Cited by 3

Decreased microRNA‐126 expression in psoriatic CD4+ T cells promotes T‐helper 17 cell differentiation and the formation of dermatitis in imiquimod‐induced psoriasis‐like mice

Wu, R., Li, X., Li, S., Tang, G., Zhang, S., Zhu, Y., Zhang, X., Deng, M., Tan, S., Luo, S., et al. (2021) · The Journal of Dermatology · doi:10.1111/1346-8138.16272 · Cited by 3

IFNγ-IL-17-IL-22+CD4+ subset and IL-22-producing cells in tumor draining lymph nodes of patients with breast cancer

Salmanpour, A., Rezaeifard, S., Kiani, R., Tahmasebi, S., Faghih, Z., & Erfani, N. (2022) · Breast Disease · doi:10.3233/bd-210084 · Cited by 3

Innate Lymphoid Cells in Mucosal Homeostasis, Infections, Autoimmune Disorders, and Tumors

Colonna, M., Fuchs, A. G., & Cella, M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-415847-4.00052-5 · Cited by 3

Effector CD4 + T Cells in the Intestines

Maynard, C. L., & Weaver, C. T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-415847-4.00034-3 · Cited by 3

Human CD4 + CD103 + cutaneous resident memory T cells are found in the circulation of healthy subjectsPreprint

Klicznik, M. M., Morawski, P. A., Höllbacher, B., Varkhande, S. R., Motley, S., Kuri-Cervantes, L., Goodwin, E. C., Rosenblum, M. D., Long, S. A., Brachtl, G., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/361758 · Cited by 4

Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto’s Thyroiditis

Erdő-Bonyár, S., Simon, D., Bajnok, A., Nörenberg, J., Serény-Litvai, T., Várnagy, Á., Kovács, K. A., Hantosi, E., Mezősi, E., & Berki, T. (2023) · Journal of Immunology Research · doi:10.1155/2023/5221658 · Cited by 2

Single-cell sequencing-based analysis of CD4 + T-cell and B-cell heterogeneity in patients with lupus nephritis

Cheng, L.-L., Tang, Z.-F., Li, M., Chen, J., Shang, S., & Huang, C.-B. (2026) · BMC Medical Genomics · doi:10.1186/s12920-025-02277-3 · Cited by 3

From Demyelination to Intervention: Natural Compounds as Emerging Therapeutic Targets in Multiple Sclerosis Neuroinflammation

Long, Z., Yang, Q., Wu, Y., Wan, L., Zeng, L., & Sun, L. (2026) · Journal of Immunology Research · doi:10.1155/jimr/6333512 · Cited by 2

Interleukin-22: A Bridge Between Epithelial Innate Host Defense and Immune Cells

Wang, X., & Ouyang, W. (2013) · Springer eBooks · doi:10.1007/978-4-431-54442-5_6 · Cited by 2

Role of rare immune cells in common variable immunodeficiency

Soltani, M., Rezaei, M., Fekrvand, S., Ganjalıkhani-Hakemi, M., Abolhassani, H., & Yazdani, R. (2021) · Pediatric Allergy and Immunology · doi:10.1111/pai.13725 · Cited by 2

CHALLENGING CORRELATIONS BETWEEN PSORIASIS SEVERITY AND TNF-α LEVELS IN HARD-TO-TREAT AREAS

Nicolescu, A. C. (2023) · FARMACIA · doi:10.31925/farmacia.2023.6.12 · Cited by 2

Integrating cuproptosis and immunosenescence: A novel therapeutic strategy in cancer treatment

Firouzjaei, A. A., & Aghaee‐Bakhtiari, S. H. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.101983 · Cited by 4

A standardizable human-based psoriasis skin model for drug development

Glasebach, H., Rupp, S., & Burger‐Kentischer, A. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1539484 · Cited by 2

Dynamic alterations and durability of T helper 22 and its corresponding cytokines following treatment in pediatric visceral leishmaniasis

Kalani, M., Choopanizadeh, M., Pourabbas, B., Pouladfar, G., Asaee, S., Ghalati, E. G., & Moravej, A. (2021) · Cytokine · doi:10.1016/j.cyto.2021.155579 · Cited by 2

Inflammatory-Driven Depletion of Filaggrin Proteins

Vestergaard, C., & Deleuran, M. S. (2014) · Springer eBooks · doi:10.1007/978-3-642-54379-1_4 · Cited by 2

CD4 T Lymphopenia, Thymic Function, Homeostatic Proliferation and Late Complications Associated with Kidney Transplantation

Saas, P., Bamoulid, J., Courivaud, C., Rebibou, J.-M., Gaugler, B., & Ducloux, D. (2013) · InTech eBooks · doi:10.5772/55330 · Cited by 2

Infections and Bacterial Colonization Including Treatment

Niebuhr, M. (2011) · Pediatric and adolescent medicine · doi:10.1159/000328177 · Cited by 2

Marked induction of CD4+CD8+ T cells with multifunctional properties by coculturing CD2+ cells with xenogeneic stromal cells

Otani, T., Toraya, T., Sugimoto, A., Okochi, A., Suzuki, M., Takeuchi, M., Yamasaki, F., Nakamura, S., & Kibata, M. (2011) · Journal of Immunological Methods · doi:10.1016/j.jim.2011.06.032 · Cited by 2

Effector and regulatory T cell subsets in diabetes-associated inflammation. Is there a connection with ST2/IL-33 axis? Perspective

Ryba-Stanisławowska, M. E., Stanisławowski, M., & Myśliwska, J. M. (2014) · Autoimmunity · doi:10.3109/08916934.2014.886198 · Cited by 2

IL-23/TH17 Pathway in Psoriasis and Inflammatory Skin Diseases

Nograles, K. E., Davidovici, B. B., & Krueger, J. G. (2011) · Springer eBooks · doi:10.1007/978-1-4419-9371-7_25 · Cited by 2

Vaccines against Mycobacterium Tuberculosis: Exploring Alternate Strategies to Combat a Near-perfect Pathogen

Filion, L. G., & Al‐Ahdal, M. N. (2013) · Mycobacterial Diseases · doi:10.4172/2161-1068.s1-003 · Cited by 2

T Cells and Their Subsets in Autoimmunity

Burkett, P. R., Pawlak, M., Peters, A., & Kuchroo, V. K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812102-3.00006-3 · Cited by 2

The Cytokine Network in Pathogenesis of Atopic Dermatitis

Higashi, N. (2017) · Nihon Ika Daigaku Igakkai Zasshi · doi:10.1272/manms.13.8 · Cited by 2

COPD and Other Inflammatory Diseases of the Lung: Focus on AhR Signaling

Beamer, C. A., Seaver, B. P., & Shepherd, D. M. (2012) · Molecular and integrative toxicology · doi:10.1007/978-1-61779-812-2_13 · Cited by 2

Peroxisome Proliferator-Activated Receptors (PPARs) Activation as Therapeutic Targets in Skin Inflammation

Aioi, A. (2020) · Trends in Immunotherapy · doi:10.24294/ti.v4.i2.1063 · Cited by 2

Inflammation of the Skin and Its Therapeutic Targets

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SUBSTANTIATION AND DIFFERENTIAL APPROACH TO OPERATIVE TREATMENT OF PATIENTS WITH PSORIATIC ARTHRITIS

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