The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques
van Gils, Janine M, Derby, Merran C, Fernandes, Luciana R, Ramkhelawon, Bhama, Ray, Tathagat D, Rayner, Katey J, Parathath, Sajesh, Distel, Emilie, Feig, Jessica L, Alvarez-Leite, Jacqueline I, Rayner, Alistair J, McDonald, Thomas O, O'Brien, Kevin D, Stuart, Lynda M, Fisher, Edward A, Lacy-Hulbert, Adam, Moore, Kathryn J·2012·Nature Immunology
DOI 10.1038/ni.2205
Cited by (364)
Items 201–300 of 364
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- The identification and function of a Netrin-1 mutation in a pedigree with premature atherosclerosisCaroline Suzanne Bruikman, Dianne Vreeken, Huayu Zhang, Marit J. van Gils, Jorge Peter, Anton Jan van Zonneveld, G. Kees Hovingh, Janine Maria van Gils · 2020 · Atherosclerosis
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- Immunological Aspects of AtherosclerosisAnna Králová, Ivana Králová Lesná, R. Poledne · 2014 · Physiological Research
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- Netrin1‐Enriched Exosomes From Genetically Modified ADSCs as a Novel Treatment for Diabetic Limb IschemiaYihong Jiang, Jiateng Hu, Chaoyi Cui, Zhaoxi Peng, Sen Yang, Jiahao Lei, Bo Li, Xinrui Yang, Jinbao Qin, Minyi Yin et al. · 2024 · Advanced Healthcare Materials
- Plaque Stabilization and Regression, from Mechanisms to Surveillance and Clinical StrategiesXi Zhang, Huanhuan Feng, Yan Han, Xiaohang Yuan, Mengting Jiang, Wei Wang, Lei Gao · 2024 · Reviews in Cardiovascular Medicine
- Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory ResponseDong Hoon Kang, Mina Choi, Soyoung Chang, Min Young Lee, Doo Jae Lee, Kyungsun Choi, Junseong Park, Eun Chun Han, Daehee Hwang, Kihwan Kwon et al. · 2015 · PLoS ONE
- Ex vivo detection of macrophages in atherosclerotic plaques using intravascular ultrasonic-photoacoustic imagingNhat Quang Bui, Kyu Kyu Hlaing, Yong Wook Lee, Hyun Wook Kang, Junghwan Oh · 2016 · Physics in Medicine and Biology
- RGMa promotes dedifferentiation of vascular smooth muscle cells into a macrophage-like phenotype in vivo and in vitroXiaofan Yuan, Hongmei Xiao, Qingzhe Hu, Guanru Shen, Xinyue Qin · 2022 · Journal of Lipid Research
- Adipose Tissue and AtherosclerosisR. Poledne, Ivana Králová Lesná, Soňa Čejková · 2015 · Physiological Research
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- Netrin-1 in Atherosclerosis: Relationship between Human Macrophage Intracellular Levels and In Vivo Plaque MorphologySusanna Fiorelli, Nicola Cosentino, Benedetta Porro, Franco Fabbiocchi, Giampaolo Niccoli, Francesco Fracassi, Nicolò Capra, Simone Barbieri, Filippo Crea, Giancarlo Marenzi et al. · 2021 · Biomedicines
- Unc5b prevents macrophage-derived foam cell migration and promotes atherosclerotic development via the P53-cuproptosis signaling pathwayXiaomeng Wang, Shijia Geng, Lina Dai, Yan Niu, Jie Chen, Chongyang Dong, Rujin Liu, Yuanjia Shi, Jing Zhang, Ningxia Zhao et al. · 2024 · Life Sciences
- HFD aggravated the arthritis and atherosclerosis by altering the intestinal status and gut microbiotaNa Shi, Shan Jiang, Yue Zhao, Yang Zhang, Xinwang Duan, Guobao Hong, Zhongshan Yang, Yuanyuan Duan, Haitao Niu · 2024 · Molecular Medicine
- The neuroimmune guidance cue netrin-1: a new therapeutic target in cardiovascular disease.Bongo Bertrand Joseph, Peng Dao Quan · 2013 · Europe PMC (PubMed Central)
- Epitranscriptomics of Ischemic Heart Disease—The IHD-EPITRAN Study Design and ObjectivesVilbert Sikorski, Pasi P. Karjalainen, Daria Blokhina, Kati Oksaharju, Jahangir Khan, Shintaro Katayama, Helena Rajala, Satu Suihko, SUVI SIRKKU TUOHINEN, Kari Teittinen et al. · 2021 · International Journal of Molecular Sciences
- The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice—Brief ReportMichele Silvestro, Cristobal F. Rivera, Dornazsadat Alebrahim, John Vlahos, Muhammad Yogi Pratama, Cuijie Lu, Claudia Tang, Zander Harpel, Rayan Sleiman Tellaoui, Ariadne L. Zias et al. · 2022 · Arteriosclerosis Thrombosis and Vascular Biology
- Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosisXi Yang, Limei Ma, Jun Zhang, Linmu Chen, Zhen Zou, Di Shen, Hui He, Lei Zhang, Jun Chen, Zhiyi Yuan et al. · 2023 · Cell & Bioscience
- The roles of immune cells in atherosclerotic calcificationJingsong Cao, Xuyu Zu, Jianghua Liu · 2021 · Vascular
- Anti-Inflammatory Strategies for Plaque Stabilization after Acute Coronary SyndromesAmos Baruch, Nicholas van Bruggen, Juyong Brian Kim, Joshua Lehrer‐Graiwer · 2013 · Current Atherosclerosis Reports
- The Heart–Brain Axis in the Artificial Intelligence Era: Integrating Old and New Insights Towards New Targeting and Innovative Neuro- and Cardio-TherapeuticsPalantzas, Andreas, Anagnostouli, Maria · 2025 · International Journal of Molecular Sciences
- Targeting Unc5b in macrophages drives atherosclerosis regression and pro-resolving immune cell functionMartin Schlegel, Yannick Cyr, Alexandra A. C. Newman, Korbinian Felix Schreyer, José Gabriel Barcia Durán, Monika Sharma, Fazli K. Bozal, Morgane Gourvest, Maxwell La Forest, Milessa Silva Afonso et al. · 2024 · Proceedings of the National Academy of Sciences
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- Neural function of Netrin-1 in precancerous lesions of the pancreasHiba Haidar, Anaïs Bellon, Karen Sleiman, Mélanie Hocine, Nicolas Rama, Nicolas Gadot, Darren R. Carpizo, Patrick Mehlen, Fanny Mann · 2025 · Nature Communications
- Pinocembrin alleviates LPS-induced depressive-like behavior in mice via the NLRP3/DCC signaling pathwayYilin Wu, Ting Hu, Hong Zheng, Jifeng Feng, Chen‐Wei Huang, Xiao-Na Zhou, Wei Wang, Chun‐Lei Jiang · 2024 · Biochemical and Biophysical Research Communications
- Upregulation of Neogenin-1 by a CREB1-BAF47 Complex in Vascular Endothelial Cells is Implicated in AtherogenesisNan Li, Hong Liu, Yujia Xue, Junliang Chen, Xiaocen Kong, Yuanyuan Zhang · 2022 · Frontiers in Cell and Developmental Biology
- UNC-5 netrin receptor B mediates osteogenic differentiation by modulating bone morphogenetic protein signaling in human adipose-derived stem cellsXinyi Hu, Yunsong Liu, Min Zhang, Yuejun Wang, Longwei Lv, Xiao Zhang, Ping Zhang, Yongsheng Zhou · 2017 · Biochemical and Biophysical Research Communications
- Molecular Biology of AtherosclerosisGöran K. Hansson · 2015 · Springer eBooks
- Guidance for Life, Cell Death, and Colorectal Neoplasia by Netrin Dependence ReceptorsChristian P. Gespach · 2012 · Advances in cancer research
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- Neurocardiac Axis Physiology and Clinical ApplicationsCaroline F. Plott, Tarek Harb, Marios Arvanitis, Gary Gerstenblith, Roger Scott Blumenthal, Thorsten Martin Leucker · 2024 · IJC Heart & Vasculature
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- Mechanisms and consequences of myeloid adhesome dysfunction in atherogenesisIrina Zhevlakova, Huan Liu, Tejasvi Dudiki, Detao Gao, Valentin P. Yakubenko, Svyatoslav Tkachenko, Olga A. Cherepanova, Eugene A. Podrez, Tatiana V. Byzova · 2024 · Cardiovascular Research
- Prediction Power on Cardiovascular Disease of Neuroimmune Guidance Cues Expression by Peripheral Blood Monocytes Determined by Machine-Learning MethodsHuayu Zhang, Obbo W Bredewold, Dianne Vreeken, Jacques M.G.J. Duijs, Hetty C. de Boer, Adriaan O. Kraaijeveld, J. Wouter Jukema, Nico H.J. Pijls, Johannes L. Waltenberger, Erik A.L. Biessen et al. · 2020 · International Journal of Molecular Sciences
- Association between serum netrin-1 and prognosis of ischemic stroke: The role of lipid component levelsYuhan Zang, Daoxia Guo, Lihua Chen, Pinni Yang, Zhengbao Zhu, Xiaoqing Bu, Tian Xu, Chongke Zhong, Aili Wang, Hao Yang Peng et al. · 2020 · Nutrition Metabolism and Cardiovascular Diseases
- The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endotheliumKerry A. Layne, Timothy Goodman, Albert Ferro, Gabriella Passacquale · 2017 · Oncotarget
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- The Role of Macrophage-Derived Netrin-1 in Inflammatory DiseasesYi Wu, Zhiying Liu, Peiqi Xu, Kai Yin, Shengjun Wang · 2025 · Biomolecules
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