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The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8–9 residues

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Antigen presentation. How sweet

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MHC Class I Ligands and Epitopes in HRSV Infection

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MHC Class I Quality Control

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Analysis of the Role of Cytosolic Aminopeptidases in the Generation of MHC-Class I Presented Peptides: a Dissertation

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Structural and Functional Studies of Proteins Involved in Antigen Processing: A Dissertation

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Untersuchung der proteolytischen Prozessierung von humanen Angiotensin-Peptiden

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On the Source of Peptides for Major Histocompatibility Class I Antigen Presentation: A Dissertation

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A Functional Study of the Major Histocompatibility Class I Antigen Presentation Pathway in Rainbow Trout (Oncorhynchus mykiss)

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Origin and Processing of MHC-I Ligands

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Endoplasmic Reticulum Aminopeptidase 2

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Factoring in Antigen Processing in Designing Antitumor T-Cell Vaccines

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HLA-B27-specific Immune Response to Influenza is Critically Dependent on ERAP-1 and on MHC-I Allelic Co-dominant Expression

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Screening for Novel Germline Rare Mutations Associated with Aggressive Prostate Cancer

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Application of Antigen Cross-Presentation Research into Patient Care

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This information is current as MHC Class I Antigen Presentation Precursors, but Is Not Required for Most Peptidase Needed to Trim Long Antigenic Tripeptidyl Peptidase II Is the Major

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Characterization of a recombinant Modified Vaccinia Virus Ankara encoding a novel synthetic immunogen of human cytomegalovirus

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Novel Insights in Ankylosing Spondylitis Biology: Mouse and Human Studies

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Aminopeptidase PILS

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Viral evasion of the MHC class I antigen presentation pathway It's a T(r)AP

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Racial Differences in the Genetics of Preeclampsia

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Investigating the mechanisms of ankylosing spondylitis-associated genetic variants

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THE ASSOCIATION OF ERAP2 GENE POLYMORPHISMS WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN HLA-B27 NEGATIVE ROMANIANS

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ERAP1 GENE POLYMORPHISMS INFLUENCE THE CLINICAL CHARACTERISTICS OF ANKYLOSING SPONDYLITIS

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Assaying Peptide Translocation by the Peptide Transporter TAP

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Factoring in Antigen Processing in Designing Antitumor T-Cell Vaccines

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Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis

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ERAP1 shows distinct regulatory mechanisms on blood pressure modulation between males and femalesPreprint

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Understanding the role UFMylation plays in prostate cancer

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Human Kidney Alternative Splicing Information Illuminates Cardiovascular-Kidney-Metabolic Syndrome RiskPreprint

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Statistical Methods for Genome-Wide Association Studies of Gene Expression, with Applications to the Genetic Study of Psoriasis.

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Additional file 1 of Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population

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Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

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Viral triggers and genetic predisposition in ocular autoimmunity: unraveling the breakdown of immune privilege and advancing targeted therapeutics

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Impact du sous-type viral et de l’apprêtement antigénique sur la présentation des épitopes du VIH-1 par les molécules HLA de classe I

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Effect of HIV antiretroviral drugs on antigen processing and epitope presentation by MHC-I to cytotoxic T cells

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Caractérisation des mécanismes de présentation des antigènes par les molécules du CMH-II

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Stratégies de vaccination basées sur l’exposition de peptides ou de protéines à la surface de particules virales : modèles de l’adénovirus 5 et du bactériophage T5

Ramdani, L. (2019) · theses.fr (ABES) · doi:10.70675/f969a6a8z33edz44c5zaa78z16d63165e115

TSSP, une protéase limitant l’apprêtement de certains antigènes du soi : étude des mécanismes impliqués et de leurs impacts sur le développement de l’encéphalomyélite auto-immune expérimentale

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Le rôle du système endosomal dans la fonction des récepteurs activateurs aux fragments Fc des immnunoglobulines : exemples du RFcyI

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Exploring the functions of IL-23 on mucosal associated invariant T (MAIT) cells – implications for immune-mediated inflammatory diseases

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Role of selective autophagy receptors in MHC-II-restricted antigen presentation and their hijacking by viruses to escape T cell immunity

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Moonlighting ERAP Aminopeptidases in Cancer: Beyond Antigen Processing

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Multiple bottlenecks constrain presentation of Mycobacterium tuberculosis antigens on MHC class IPreprint

Leddy, O. K., Gunnarsson, C., Holec, P. V., Ren, D., Martello, C., Birnbaum, M. E., White, F. M., & Bryson, B. D. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.16.759551

BindingDB Entry 50048297: Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.

BindingDB (2018) · UC San Diego · doi:10.7270/q26m390j

BindingDB Entry 50047788: Discovery of potent and selective inhibitors of human aminopeptidases ERAP1 and ERAP2 by screening libraries of phosphorus-containing amino acid and dipeptide analogues.

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BindingDB Entry 50045703: 3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of M1 aminopeptidases with immune-regulating properties.

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BindingDB Entry 50020985: ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights.

BindingDB (2025) · UC San Diego · doi:10.7270/q2pn9b72

BindingDB Entry 50013831: Modulators of hERAP2 discovered by high-throughput screening.

BindingDB (2022) · UC San Diego · doi:10.7270/q29z98pr

BindingDB Entry 50043324: Novel selective inhibitors of aminopeptidases that generate antigenic peptides.

BindingDB (2014) · UC San Diego · doi:10.7270/q2j38v00

Complexe Majeur d’Histocompatibilité et génomique fonctionnelle dans les spondylarthrites

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The ER aminopeptidases, ERAP1 and ERAP2, Synergize to Self-Modulate their Respective Activities

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Complexity, contradictions, and conundrums: studying post‐proteasomal proteolysis in HLA class I antigen presentation

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Concerted In Vitro Trimming of Viral HLA-B27-Restricted Ligands by Human ERAP1 and ERAP2 Aminopeptidases

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Trimming of MHC Class I Ligands by ERAP Aminopeptidases

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ERAP1–ERAP2 Dimerization Increases Peptide-Trimming Efficiency

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