Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
kConFab, Lim, Elgene, Vaillant, François, Wu, Di, Forrest, Natasha C, Pal, Bhupinder, Hart, Adam H, Asselin-Labat, Marie-Liesse +13 more·2009·Nature Medicine
DOI 10.1038/nm.2000
Cited by (1,001)
Items 201–300 of 1,001
- Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterizationRenaud Sabatier, Pascal Finetti, Arnaud Guillé, José Adélaı̈de, Max Chaffanet, Patrice Viens, Daniel Birnbaum, François Bertucci · 2014 · Molecular Cancer
- The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERαAdrian Britschgi, Stephan Duss, Sungeun Kim, Joana Pinto Couto, Heike Brinkhaus, Shany Koren, Duvini De Silva, Kirsten D. Mertz, Daniela Kaup, Zsuzsanna Varga et al. · 2017 · Nature
- Quantification of regenerative potential in primary human mammary epithelial cellsJelena R. Linnemann, Haruko Miura, Lisa K. Meixner, Martin Irmler, Uwe J. Kloos, Benjamin Hirschi, Harald S. Bartsch, Steffen Sass, Johannes Beckers, Fabian Joachim Theis et al. · 2015 · Development
- Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneityGeoffrey M. Wahl, Benjamin T. Spike · 2017 · npj Breast Cancer
- Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State PlasticityChristopher Dravis, Chi‐Yeh Chung, Nikki K. Lytle, Jaslem Herrera-Valdez, Gidsela Luna, Christy L. Trejo, Tannishtha Reya, Geoffrey M. Wahl · 2018 · Cancer Cell
- The Cancer Stem-Cell Hypothesis: Its Emerging Role in Lung Cancer Biology and Its Relevance for Future TherapyJohn D. O’Flaherty, Martin P. Barr, Dean Anthony Fennell, Derek J. Richard, John Vincent Reynolds, John J. O’Leary, Kenneth John O'Byrne · 2012 · Journal of Thoracic Oncology
- Wnt/β-catenin Signaling in Normal and Cancer Stem CellsKenneth C. Valkenburg, Carrie R. Graveel, Cassandra R. Diegel, Zhendong A. Zhong, Bart O. Williams · 2011 · Cancers
- Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional ProfilingJustin A. Colacino, Ebrahim Azizi, Michael D. Brooks, Ramdane A Harouaka, Shamileh Fouladdel, Sean McDermott, Michael Lee, David R. Hill, Julie M. Madden, Julie L. Boerner et al. · 2018 · Stem Cell Reports
- Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signaturesPeter Kabos, Jessica Finlay-Schultz, Chunling Li, Enos C. Kline, Christina A. Finlayson, Joshua A. Wisell, Christopher A Manuel, Susan M. Edgerton, Joshua Chuck Harrell, ANTHONY D. ELIAS et al. · 2012 · Breast Cancer Research and Treatment
- Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescenceMaja Sedic, Adam Skibinski, Nelson E. Brown, Mercedes Gallardo, Peter Mulligan, Paula Martínez, Patricia J. Keller, Eugene Glover, Andrea L. Richardson, Janet M. Cowan et al. · 2015 · Nature Communications
- The RasGAP Gene, RASAL2, Is a Tumor and Metastasis SuppressorSara Koenig McLaughlin, Sarah Naomi Olsen, Benjamin T. Dake, Thomas De Raedt, Elgene Lim, Roderick Terry Bronson, Rameen Beroukhim, Kornélia Polyák, Myles A Brown, Charlotte Kuperwasser et al. · 2013 · Cancer Cell
- SLUG: Critical regulator of epithelial cell identity in breast development and cancerSarah M. Phillips, Charlotte Kuperwasser · 2014 · Cell Adhesion & Migration
- Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast CancerDeli Liu, Huan Xiong, Angela E. Ellis, Nicole C. Northrup, Carlos O. Rodriguez, Ruth M O'Regan, Stephen Dalton, Shaying Zhao · 2014 · Cancer Research
- Identification of quiescent and spatially restricted mammary stem cells that are hormone responsiveNai Yang Fu, Anne C. Rios, Bhupinder Pal, Charity W. Law, Paul R. Jamieson, Ruijie Liu, François Vaillant, Felicity C. Jackling, Kevin He Liu, Gordon K. Smyth et al. · 2017 · Nature Cell Biology
- Overview of recent advances in metastatic triple negative breast cancerDavid O'Reilly, Maha AlSendi, Catherine Margaret Kelly · 2021 · World Journal of Clinical Oncology
- Assessment of Breast Cancer Risk Factors Reveals Subtype HeterogeneityJohanna Holm, Louise Eriksson, Alexander Ploner, Mikael Eriksson, Mattias Rantalainen, Jingmei Li, Per N Hall, Kamila Czene · 2017 · Cancer Research
- A 3′-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysisTrupti Paranjape, Helen Heneghan, Robert M. Lindner, Florence K. Keane, Aaron E. Hoffman, Antoinette Hollestelle, Jemima J. Dorairaj, Kimberly Geyda, Cory Pelletier, Sunitha V. Nallur et al. · 2011 · The Lancet Oncology
- The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low Xist ExpressionMarion A. Salvador, Julien Wicinski, Olivier Cabaud, Yves Toiron, Pascal Finetti, Emmanuelle Josselin, Hélène Lelièvre, Laurence Kraus‐Berthier, Stéphane Depil, François Bertucci et al. · 2013 · Clinical Cancer Research
- Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial CellsChristopher Dravis, Benjamin T. Spike, Joshua Chuck Harrell, Claire Johns, Christy L. Trejo, E. Michelle Southard‐Smith, Charles M. Perou, Geoffrey M. Wahl · 2015 · Cell Reports
- Form and Function: how Estrogen and Progesterone Regulate the Mammary Epithelial HierarchyLisa M. Arendt, Charlotte Kuperwasser · 2015 · Journal of Mammary Gland Biology and Neoplasia
- Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancerSproul, Duncan, Nestor, Colm, Culley, Jayne, Dickson, Jacqueline H., Dixon, J. Michael, Harrison, David J., Meehan, Richard R., Sims, Andrew H., Ramsahoye, Bernard H. · 2011 · Proceedings of the National Academy of Sciences
- Breast cancer stem cells: treatment resistance and therapeutic opportunitiesFares Al‐Ejeh, Chanel Elisha Smart, Brian J. Morrison, Georgia Chenevix‐Trench, José Alejandro López, Sunil R. Lakhani, Michael Paul Brown, Kum Kum Khanna · 2011 · Carcinogenesis
- Immune Landscape of Breast CancersDivya Nagarajan, Stéphanie McArdle · 2018 · Biomedicines
- MAP3K4/CBP-Regulated H2B Acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem CellsAmy N. Abell, Nicole Vincent Jordan, Weichun Huang, Aleix Prat, Alicia A. Midland, Nancy Lassignal Johnson, Deborah A. Granger, Piotr A. Mieczkowski, Charles M. Perou, Shawn M. Gomez et al. · 2011 · Cell stem cell
- Links between cancer stem cells and epithelial– mesenchymal transitionYaling Tang, Shasha Wang, Jian Dong Jiang, Xin‐hua Liang · 2015 · OncoTargets and Therapy
- Mammary stem cells and progenitors: targeting the roots of breast cancer for preventionPirashaanthy Tharmapalan, Mathepan Jeya Mahendralingam, Hal K. Berman, Rama Khokha · 2019 · The EMBO Journal
- ANTXR1, a Stem Cell-Enriched Functional Biomarker, Connects Collagen Signaling to Cancer Stem-like Cells and Metastasis in Breast CancerDaohong Chen, Poornima Bhat‐Nakshatri, Chirayu Pankaj Goswami, Sunil Badve, Harikrishna Nakshatri · 2013 · Cancer Research
- Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and predictionPierre‐Emmanuel Colombo, Fernanda Milanezi, Britta Weigelt, Jorge Sergio Reis-Filho · 2011 · Breast Cancer Research
- Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4Diana M. Cittelly, Jessica Finlay-Schultz, Erin N. Howe, Nicole S. Spoelstra, Sunshine Daddario Axlund, P Hendricks, Britta M. Jacobsen, Carol A. Sartorius, Jennifer K. Richer · 2012 · Oncogene
- Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast CancerKeli Xu, Jerry Usary, Philaretos C. Kousis, Aleix Prat, Dong‐Yu Wang, Jessica R. Adams, Wei Wang, Amanda J. Loch, Tao Deng, Wei Zhao et al. · 2012 · Cancer Cell
- Tumor size and survival in breast cancer—a reappraisalWilliam David Foulkes, Jorge Sergio Reis-Filho, Steven Alexander Narod · 2010 · Nature Reviews Clinical Oncology
- Luminal Expression of PIK3CA Mutant H1047R in the Mammary Gland Induces Heterogeneous TumorsDominique S. Meyer, Heike Brinkhaus, Urs Müller, Matthias Müller, Robert D. Cardiff, Mohamed Bentires‐Alj · 2011 · Cancer Research
- BRCA1 and Breast Cancer: Molecular Mechanisms and Therapeutic StrategiesXiaoyu Fu, Wei Tan, Qibin Song, Huadong Pei, Juanjuan Li · 2022 · Frontiers in Cell and Developmental Biology
- Breast cancer stem cells and epithelial mesenchymal plasticity – Implications for chemoresistanceCletus Pinto, Edwin Widodo, Mark C. Waltham, Erik W. Thompson · 2013 · Cancer Letters
- From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancerBenjamin Tiede, Yibin Kang · 2011 · Cell Research
- Insights into cancer metastasis from a clinicopathologic perspective: Epithelial‐Mesenchymal Transition is not a necessary stepMichael Herman Chui · 2012 · International Journal of Cancer
- Accumulation of Multipotent Progenitors with a Basal Differentiation Bias during Aging of Human Mammary EpitheliaJames C. Garbe, Francois Pepin, Fanny A. Pelissier, Klara Sputova, Agla J. Fridriksdottir, Diana E. Guo, René Villadsen, Morag Park, Ole W. Petersen, Alexander D. Borowsky et al. · 2012 · Cancer Research
- Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2kConFab Investigators, Valentina Silvestri, EMBRACE, Daniel Barrowdale, Anna Marie Mulligan, Susan L. Neuhausen, Stephen B. Fox, Beth Y. Karlan, Gillian Mitchell, Paul Andrew James et al. · 2016 · Breast Cancer Research
- Mammary Development and Breast Cancer: A Wnt PerspectiveQing Cissy Yu, Esther M. Verheyen, Yi Arial Zeng · 2016 · Cancers
- A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial CancersBryan A. Smith, Nikolas G. Balanis, Avinash Nanjundiah, Katherine M. Sheu, Brandon L. Tsai, Qingfu Zhang, Jung Wook Park, Michael J. Thompson, Jiaoti Huang, Owen N. Witte et al. · 2018 · Cell Reports
- A Single Cell Atlas of the Healthy Breast Tissues Reveal Clinically Relevant Clusters of Breast Epithelial CellsPoornima Bhat‐Nakshatri, Hongyu Gao, Sheng Liu, Patrick C. McGuire, Xiaoling Xuei, Jun Wan, Yunlong Liu, Sandra K. Althouse, Austyn B. Colter, George Earl Sandusky et al. · 2020 · Cell Reports Medicine
- Estrogen and Progesterone in Normal Mammary Gland Development and in CancerJulia Stingl · 2010 · Hormones and Cancer
- Stem Cells in the Human BreastOLE WILLIAM PETERSEN, Kornélia Polyák · 2010 · Cold Spring Harbor Perspectives in Biology
- Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activityJiyoung Kim, René Villadsen, Thérese Sørlie, Louise Fogh, Signe Z. Grønlund, Agla J. Fridriksdottir, Irene Kuhn, Fritz E Rank, Vera Timmermans Wielenga, Hiroko Kato Solvang et al. · 2012 · Proceedings of the National Academy of Sciences
- Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14Marie-Liesse Asselin-Labat, Kate D. Sutherland, François Vaillant, David E. Gyorki, Di Wu, Sheridan L Holroyd, Kelsey A. Breslin, Teresa A. Ward, Wei Shi, Mary L. Bath et al. · 2011 · Molecular and Cellular Biology
- Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor NetworksDavide Pellacani, Misha Bilenky, Nagarajan Kannan, Alireza Heravi‐Moussavi, David J. H. F. Knapp, Sitanshu Gakkhar, Michelle Moksa, Annaïck Carles, Richard A. Moore, Andrew J. J. Mungall et al. · 2016 · Cell Reports
- Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milkAlecia‐Jane Twigger, Lisa K. Engelbrecht, Karsten Bach, Isabel Schultz-Pernice, Sara Pensa, Jack Stenning, Stefania Petricca, Christina Scheel, Walid T. Khaled · 2022 · Nature Communications
- Effects of estrogen on the proportion of stem cells in the breastBruno M. Simões, Marco Piva, Oihana Iriondo, Valentine Comaills, Jose A. López-Ruiz, Iñaki Zabalza, Jon A. Mieza, Olga Acinas, María dM Vivanco · 2010 · Breast Cancer Research and Treatment
- c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancerJoseph L. Regan, Howard D. Kendrick, F-A Magnay, Vida Vafaizadeh, Bernd Groner, Matthew John Smalley · 2011 · Oncogene
- NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formationKai Miao, J. Lei, Monica V. Valecha, Aiping Zhang, Jun Xu, Lijian Wang, Xueying Lyu, Si Chen, Zheng-Qiang Miao, Xin Zhang et al. · 2020 · Nature Communications
- CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancerÓlafur Andri Stefánsson, Jon Gunnlaugur Jonasson, Kristrún Ólafsdóttir, Hólmfríður Hilmarsdóttir, Guðríður H. Ólafsdóttir, Manel Esteller, Óskar Þór Jóhannsson, Jorunn Erla Eyfjord · 2011 · Epigenetics
- BRCA1 is a negative modulator of the PRC2 complexLan Wang, Xianzhuo Zeng, Shuai Chen, Liya Ding, Jian Zhong, Jonathan C. Zhao, Liguo Wang, Aaron L. Sarver, Antonius A. Koller, Jizu Zhi et al. · 2013 · The EMBO Journal
- ALDH1A1 expression correlates with clinicopathologic features and poor prognosis of breast cancer patients: a systematic review and meta-analysisYing Liu, Donglai Lv, Jiang‐Jie Duan, Senlin Xu, Jingfang Zhang, Xiaojun Yang, Xia Zhang, You‐Hong Cui, Xiu‐Wu Bian, Shi‐Cang Yu · 2014 · BMC Cancer
- A single-cell atlas enables mapping of homeostatic cellular shifts in the adult human breastAustin D. Reed, Sara Pensa, Adi Steif, Jack Stenning, Daniel J. Kunz, Linsey J. Porter, Kui Hua, Peng He, Alecia‐Jane Twigger, Abigail J. Q. Siu et al. · 2024 · Nature Genetics
- Health disparities in breast cancer: biology meets socioeconomic statusBarbara Karen Dunn, Tanya Agurs‐Collins, Doris Browne, Ronald A. Lubet, Karen A. Johnson · 2010 · Breast Cancer Research and Treatment
- Targeting Unique Metabolic Properties of Breast Tumor Initiating CellsWeiguo Feng, Andrew J. Gentles, Ramesh V. Nair, Min Huang, Yuan Lin, Cleo Y. Lee, Shang Cai, Ferenc A. Scheeren, Angera H. Kuo, Maximilian Diehn · 2014 · Stem Cells
- Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor InitiationSarah M. Phillips, Aleix Prat, Maja Sedic, Theresa A. Proia, Ania Wronski, Sohini Mazumdar, Adam Skibinski, Stephanie Harkey Shirley, Charles M. Perou, Grace Gill et al. · 2014 · Stem Cell Reports
- Combined deletion of Pten and p53 in mammary epithelium accelerates triple‐negative breast cancer with dependency on eEF2KJeff C. Liu, Véronique Voisin, Sharon Wang, Dong‐Yu Wang, Robert A. Jones, Alessandro Datti, David Uehling, Rima Al‐awar, Sean E. Egan, Gary D. Bader et al. · 2014 · EMBO Molecular Medicine
- Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancersPeter Kabos, James M. Haughian, Xinshuo Wang, Wendy W. Dye, Christina A. Finlayson, ANTHONY D. ELIAS, Kathryn B. Horwitz, Carol A. Sartorius · 2010 · Breast Cancer Research and Treatment
- TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancerAlejandra Bruna, Wendy Greenwood, John P. C. Le Quesne, Andrew Erich Teschendorff, Diego Miranda‐Saavedra, Oscar M. Rueda, José Luís Sandoval, Ana Tufegdžić Vidaković, Amel Saadi, Paul D.P. Pharoah et al. · 2012 · Nature Communications
- Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA DamageA. C. SAU, Rosanna Lau, Miguel A. Cabrita, Emma Nolan, Peter Anthony Crooks, Jane E. Visvader, M.A. Christine Pratt · 2016 · Cell stem cell
- FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic diseaseSusana García‐Recio, Aatish Thennavan, Michael P. East, Joel S. Parker, Juan Miguel Cejalvo, Joseph P. Garay, Daniel P. Hollern, Xiaping He, Kevin Raynard Mott, Patricia Galván et al. · 2020 · Journal of Clinical Investigation
- Epigenetic Regulation of Cell Type–Specific Expression Patterns in the Human Mammary EpitheliumMaruyama, Reo, Choudhury, Sibgat, Kowalczyk, Adam, Bessarabova, Marina, Beresford-Smith, Bryan, Conway, Thomas, Kaspi, Antony, Wu, Zhenhua, Nikolskaya, Tatiana, Merino, Vanessa F. et al. · 2011 · PLoS Genetics
- The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapyMun Ngah Hui, Aurélie Cazet, Radhika Nair, D. Neil Watkins, Sandra A O'Toole, Alexander Swarbrick · 2013 · Breast Cancer Research
- RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cellsMaaike P.A. van Bragt, Xin Hu, Ying Xie, Zhe Li · 2014 · eLife
- Lineage-Biased Stem Cells Maintain Estrogen-Receptor-Positive and -Negative Mouse Mammary Luminal LineagesChunhui Wang, John R. Christin, Maja H. Oktay, Wenjun Guo · 2017 · Cell Reports
- Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolutionRoxane M. Pommier, Amélien Sanlaville, Laurie Tonon, Janice Kielbassa, Emilie Thomas, Anthony Ferrari, Anne-Sophie Sertier, Frédéric Hollande, Pierre Martinez, Agnès Tissier et al. · 2020 · Nature Communications
- Basal Cell Signaling by p63 Controls Luminal Progenitor Function and Lactation via NRG1Nicole Forster, Srinivas Vinod Saladi, Maaike P.A. van Bragt, Mary E. Sfondouris, Frank E. Jones, Zhe Li, Leif William Ellisen · 2014 · Developmental Cell
- EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast CancerHelen Schneck, Berthold Gierke, Frauke Uppenkamp, Bianca Behrens, Dieter Niederacher, Nikolas Hendrik Stoecklein, Markus F. Templin, Michael Pawlak, Tanja Natascha Fehm, Hans J. Neubauer et al. · 2015 · PLoS ONE
- Epigenetic Modifications in Breast Cancer and Their Role in Personalized MedicineÓlafur Andri Stefánsson, Manel Esteller · 2013 · American Journal Of Pathology
- DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenograftsLong V. Nguyen, Claire L. Cox, Peter D. Eirew, David J. H. F. Knapp, Davide Pellacani, Nagarajan Kannan, Annaïck Carles, Michelle Moksa, Sneha Balani, Sohrab P. Shah et al. · 2014 · Nature Communications
- Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage RelationshipsChi‐Yeh Chung, Zhibo Ma, Christopher Dravis, Sebastian Preißl, Olivier Poirion, Gidsela Luna, Xiaomeng Hou, Rajshekhar R. Giraddi, Bing Ren, Geoffrey M. Wahl · 2019 · Cell Reports
- Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic CharacteristicsSonam Bhatia, Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy, Peter Andrews, Cheng Fan, Charles M. Perou, Jonathan B. Preall et al. · 2022 · Cancer Research
- Breast Cancer Stem Cells: Current Advances and Clinical ImplicationsMing Luo, Shawn G. Clouthier, Yadwinder S. Deol, Suling Liu, Sunitha Nagrath, Ebrahim Azizi, Max S. Wicha · 2015 · Methods in molecular biology
- Invasive Breast CarcinomaAyşegül A. Şahin, H. Zhang · 2014 · Elsevier eBooks
- Revisiting the concept of cancer stem cells in prostate cancerZhu A. Wang, Michael M. Shen · 2010 · Oncogene
- Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a–LCOR axisToni Celià-Terrassa, Daniel Dan Liu, Abrar Choudhury, Xiang Hang, Yong Wei, Jose Zamalloa, Raymundo Alfaro‐Aco, Rumela Chakrabarti, Yi‐Zhou Jiang, Bong Ihn Koh et al. · 2017 · Nature Cell Biology
- The Cancer Stem Cell Hypothesis: A Guide to Potential Molecular TargetsAlessandro Allegra, Andrea Alonci, Giuseppa Penna, Vanessa Innao, Demetrio Gabriele Gerace, Francesco Rotondo, Caterina Musolino · 2014 · Cancer Investigation
- BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexesHiroyuki Sasanuma, Masataka Tsuda, Suguru Morimoto, Liton Kumar Saha, Md Maminur Rahman, Yusuke Kiyooka, Haruna Fujiike, Andrew D. Cherniack, Junji Itou, Elsa Callén et al. · 2018 · Proceedings of the National Academy of Sciences
- KIF14 Promotes AKT Phosphorylation and Contributes to Chemoresistance in Triple-Negative Breast CancerStina Mui Singel, Crystal Cornelius, Elma Zaganjor, Kimberly G. Batten, Venetia Rumnong Sarode, Dennis L. Buckley, Yan Shen Peng, George B. John, Hsiao Ching Li, Navid Sadeghi et al. · 2014 · Neoplasia
- Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsetsNagarajan Kannan, Long V. Nguyen, Maisam Makarem, Yifei Dong, Kingsley Shih, Peter D. Eirew, Afshin Raouf, Joanne T. Emerman, Connie J. Eaves · 2014 · Proceedings of the National Academy of Sciences
- Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor MetastasisYan Li, Zan Lv, Shaohua Zhang, Zhuo Wang, Lingjuan He, Muxue Tang, Wenjuan Pu, Huan Zhao, Zhenqian Zhang, Qihui Shi et al. · 2020 · Developmental Cell
- Targeted therapy for triple‐negative breast cancer: Where are we?Michael Joe Duffy, Patricia M. McGowan, John Paul Crown · 2012 · International Journal of Cancer
- GABA(A) Receptor Pi (GABRP) Stimulates Basal-like Breast Cancer Cell Migration through Activation of Extracellular-regulated Kinase 1/2 (ERK1/2)Gina M. Sizemore, Steven T. Sizemore, Darcie D. Seachrist, Ruth A. Keri · 2014 · Journal of Biological Chemistry
- Epithelial‐to‐mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneityDeli Hong, Andrew J. Fritz, Sayyed Kaleem Zaidi, André J. van Wijnen, Jeffrey A. Nickerson, Anthony N. Imbalzano, Jane B. Lian, Janet Lee Stein, Gary S. Stein · 2018 · Journal of Cellular Physiology
- Maintenance of hormone responsiveness in luminal breast cancers by suppression of NotchJames M. Haughian, Mauricio P. Pinto, Joshua Chuck Harrell, Brian Bliesner, Kristiina M. Joensuu, Wendy W. Dye, Carol A. Sartorius, Aik Choon Tan, Päivi Heikkilä, Charles M. Perou et al. · 2011 · Proceedings of the National Academy of Sciences
- R-spondin1 is a novel hormone mediator for mammary stem cell self-renewalCheguo Cai, Qing Cissy Yu, Weimin Jiang, Wei Liu, Wenqian Song, Hua Yu, Lei Zhang, Ying Yang, Yi Arial Zeng · 2014 · Genes & Development
- Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast CancerHua Wang, Dongxi Xiang, Ben Liu, Aina He, Helena J. Randle, Kelvin Xi Zhang, Anushka Dongre, Norman Sachs, Allison P. Clark, Luwei Tao et al. · 2019 · Cell
- Steroid Hormones, Steroid Receptors, and Breast Cancer Stem CellsJessica Finlay-Schultz, Carol A. Sartorius · 2015 · Journal of Mammary Gland Biology and Neoplasia
- Generation of tumor-initiating cells by exogenous delivery of OCT4transcription factorAdriana S. Beltrán, Ashley G. Rivenbark, Bryan T Richardson, Xinni Yuan, Haili Quian, John P Hunt, Eric I. Zimmerman, Lee M. Graves, Pilar Blancafort · 2011 · Breast Cancer Research
- MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasionJessica Bockhorn, Kathy Yee, Ya-Fang Chang, Aleix Prat, Dezheng Huo, Chika Nwachukwu, Rachel Dalton, Simo Huang, Kaitlin E. Swanson, Charles M. Perou et al. · 2012 · Breast Cancer Research and Treatment
- Hyaluronan Mediated Motility Receptor (HMMR) Encodes an Evolutionarily Conserved Homeostasis, Mitosis, and Meiosis Regulator Rather than a Hyaluronan ReceptorZhengcheng He, Lin Mei, Marisa Connell, Christopher A. Maxwell · 2020 · Cells
- ErbB receptor tyrosine kinase/NF-κB signaling controls mammosphere formation in human breast cancerKunihiko Hinohara, Seiichiro Kobayashi, Hajime Kanauchi, Seiichiro Shimizu, Kotoe Nishioka, Ei-ichi Tsuji, Kei-ichiro Tada, Kazuo Umezawa, Masaki Mori, Toshihisa Ogawa et al. · 2012 · Proceedings of the National Academy of Sciences
- Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesisPang‐Kuo Lo, Yongshu Zhang, Benjamin Wolfson, Ramkishore Gernapudi, Yuan Yao, Nadire Duru, Qun Yong Zhou · 2016 · Oncotarget
- Poly (ADP-Ribose) Polymerase as a Novel Therapeutic Target in CancerChristina M. Annunziata, Joyce O’Shaughnessy · 2010 · Clinical Cancer Research
- Role of microRNAs in the Regulation of Breast Cancer Stem CellsSuling Liu, Shawn G. Clouthier, Max S. Wicha · 2012 · Journal of Mammary Gland Biology and Neoplasia
- Mapping cancer originsR. Gilbertson · 2011 · Cell
- Clinical Implications of Gene Dosage and Gene Expression Patterns in Diploid Breast CarcinomaToshima Z. Parris, Anna Danielsson, Szilárd Nemes, Anikó Kovács, Ulla Delle, Ghita Fallenius, Elin Möllerström, Per Karlsson, Khalil Helou · 2010 · Clinical Cancer Research
- Estrogen receptor signaling is reprogrammed during breast tumorigenesisDavid Chi, Hari Singhal, Lewyn Li, Tengfei Xiao, Weihan Liu, Matthew J Pun, Rinath M. Jeselsohn, Housheng He, Elgene Lim, Raga Vadhi et al. · 2019 · Proceedings of the National Academy of Sciences
- Breast Cancer Stem CellsJudy S. Crabtree, Lucio Miele · 2018 · Biomedicines