Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
kConFab, Lim, Elgene, Vaillant, François, Wu, Di, Forrest, Natasha C, Pal, Bhupinder, Hart, Adam H, Asselin-Labat, Marie-Liesse +13 more·2009·Nature Medicine
DOI 10.1038/nm.2000
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- Heterogeneity of breast cancer: etiology and clinical relevanceVanessa Almendro, Gemma Fuster · 2011 · Clinical & Translational Oncology
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