The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Hematopoietic stem cell niche maintenance during homeostasis and regeneration
Open accessAbstract
The bone marrow niche has mystified scientists for many years, leading to widespread investigation to shed light into its molecular and cellular composition. Considerable efforts have been devoted toward uncovering the regulatory mechanisms of hematopoietic stem cell (HSC) niche maintenance. Recent advances in imaging and genetic manipulation of mouse models have allowed the identification of distinct vascular niches that have been shown to orchestrate the balance between quiescence, proliferation and regeneration of the bone marrow after injury. Here we highlight the recently discovered intrinsic mechanisms, microenvironmental interactions and communication with surrounding cells involved in HSC regulation, during homeostasis and in regeneration after injury and discuss their implications for regenerative therapy.
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Cites
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Cited by
Ambrosi, T. H., Scialdone, A., Graja, A., Gohlke, S., Jank, A.-M., Bocian, C., Woelk, L., Fan, H., Logan, D. W., Schürmann, A., et al. (2017) · Cell Stem Cell · doi:10.1016/j.stem.2017.02.009 · Cited by 856
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Blood vessel formation and function in bone
Sivaraj, K. K., & Adams, R. H. (2016) · Development · doi:10.1242/dev.136861 · Cited by 441
Does niche competition determine the origin of tissue-resident macrophages?
Guilliams, M., & Scott, C. L. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.42 · Cited by 409
Fetal monocytes and the origins of tissue-resident macrophages
Hoeffel, G., & Ginhoux, F. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.01.001 · Cited by 401
Metadata
- Authors
- Mendelson, A., & Frenette, P. S.
- Venue
- Nature Medicine
- Published
- 2014-08
- Volume
- 20
- Issue
- 8
- Pages
- 833-846
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2052730253
- Cited by
- 792
- References
- 35
- FWCI
- 46.74
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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