Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

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Items 701–800 of 1,001

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8. Organoids as predictive platforms: advancing disease modeling, therapeutic innovation, and drug delivery systems
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9. In-Plate Cryopreservation of 2D and 3D Cell Models: Innovative Tools for Biomedical Research and Preclinical Drug Discovery
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11. Droplet-engineered organoids recapitulate parental tissue transcriptome with inter-organoid homogeneity and inter-tumor cell heterogeneity
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13. Bioengineering Liver Organoids for Diseases Modelling and Transplantation
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14. Establishment and characterization of a new intrahepatic cholangiocarcinoma cell line derived from a Chinese patient
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15. Stimulatory Anticancer Effect of Resveratrol Mediated by G Protein-Coupled Estrogen Receptor in Colorectal Cancer
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16. Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance
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17. In silico study of heterogeneous tumour-derived organoid response to CAR T-cell therapy
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18. In vivo organoid growth monitoring by stimulated Raman histology
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19. ATP6V1D drives hepatocellular carcinoma stemness and progression via both lysosome acidification-dependent and -independent mechanisms
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20. Establishment of hepatocellular carcinoma patient-derived xenografts from image-guided percutaneous biopsies
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21. Overview of Tissue Engineering Concepts and Applications
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22. The Anti-Tumor Effect of Nab-Paclitaxel Proven by Patient-Derived Organoids
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23. Integrating Engineering, Automation, and Intelligence to Catalyze the Biomedical Translation of Organoids
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24. Phenotypical screening on metastatic PRCC-TFE3 fusion translocation renal cell carcinoma organoids reveals potential therapeutic agents
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25. Steroidal saponins from Trillium tschonoskii rhizome repress cancer stemness and proliferation of intrahepatic cholangiocarcinoma
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26. Instructive Hydrogels for Primary Tumor Cell Culture: Current Status and Outlook
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27. Application of tumoroids derived from advanced colorectal cancer patients to predict individual response to chemotherapy
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28. Remodelling and Improvements in Organoid Technology to Study Liver Carcinogenesis in a Dish
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29. Modelling adult stem cells and their niche in health and disease with epithelial organoids
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30. Non-canonical activation of MAPK signaling by the lncRNA ASH1L-AS1-encoded microprotein APPLE through inhibition of PP1/PP2A-mediated ERK1/2 dephosphorylation in hepatocellular carcinoma
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31. From niche to organoid: Engineering bone tissues through microenvironmental insights
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32. MicroRNA Landscape in Hepatocellular Carcinoma: Metabolic Re-Wiring, Predictive and Diagnostic Biomarkers, and Emerging Therapeutic Targets
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33. Antitumor effect of WEE1 blockade as monotherapy or in combination with cisplatin in urothelial cancer
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34. Translational and Clinical Relevance of PDX‐Derived Organoid Models in Oncology Drug Discovery and Development
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35. Splice‐switch oligonucleotide‐based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC ‐driven hepatocellular carcinoma
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36. Comprehensive drug response profiling and pan-omic analysis identified therapeutic candidates and prognostic biomarkers for Asian cholangiocarcinoma
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37. Organoids as an Enabler of Precision Immuno-Oncology
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38. Can Organoid Model Reveal a Key Role of Extracellular Vesicles in Tumors? A Comprehensive Review of the Literature
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39. Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis
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40. Establishment of a novel overlay culture method that enables immune response assessment using gastric cancer organoids
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41. Advancements and application prospects of three-dimensional models for primary liver cancer: a comprehensive review
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42. Progress, application and challenges of liver organoids
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43. Self-assembled metal-polyphenolic based multifunctional nanomedicine to improve therapy treatment of pancreatic cancer by inhibition of glutamine metabolism
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44. Development of patient-derived lymphomoids with preserved tumor architecture for lymphoma therapy screening
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45. Management of intrahepatic cholangiocarcinoma: a review for clinicians
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46. Patient-Derived Organoid Models for NKT Cell-Based Cancer Immunotherapy
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47. Tumor organoids in cancer medicine: from model systems to natural compound screening
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48. Hepatotoxicity evaluation method through multiple-factor analysis using human pluripotent stem cell derived hepatic organoids
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49. Proliferation of human hepatocellular carcinoma cells from surgically resected specimens under conditionally reprogrammed culture
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50. Application and research progress of organoids in cholangiocarcinoma and gallbladder carcinoma.
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51. Future Match Making: When Pediatric Oncology Meets Organoid Technology
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52. To Better Generate Organoids, What Can We Learn From Teratomas?
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53. Recapitulating the Cancer Microenvironment Using Bioprinting Technology for Precision Medicine
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54. Engineered liver tissue in vitro to mimic liver functions and its biomedical applications
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55. Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification
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56. Three-Dimensional Cell Culture Systems in Pediatric and Adult Brain Tumor Precision Medicine
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57. Liver Buds and Liver Organoids: New Tools for Liver Development, Disease and Medical Application
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58. An information-theoretic approach for measuring the distance of organ tissue samples using their transcriptomic signatures
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59. Fast formation and maturation enhancement of human liver organoids using a liver-organoid-on-a-chip
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60. Bioprinting of patient-derived heterogeneous renal cell carcinoma organoids for personalized therapy
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61. Modeling neurodegenerative diseases with brain organoids: from development to disease applications
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62. The CellRaft AIRⓇ system: A novel system enabling organoid imaging, identification, and isolation
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63. Modelling cancer metabolism in vitro: current improvements and future challenges
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64. Gastrointestinal Cancer Patient Derived Organoids at the Frontier of Personalized Medicine and Drug Screening
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65. Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumors
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66. An organoid library of human esophageal squamous cell carcinomas (ESCCs) uncovers the chemotherapy-resistant ESCC features
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67. Anti-cancer drug sensitivity testing and preclinical evaluation of the anti-cancer potential of WEE1 inhibitor in triple-negative breast cancer patient-derived organoids and xenograft models
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68. 3D culture system containing gellan gum restores oncogene dependence in ROS1 rearrangements non-small cell lung cancer
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69. New Therapeutic Approaches in Cystic Fibrosis
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70. Combinatorial Effect of Magnetic Field and Radiotherapy in PDAC Organoids: A Pilot Study
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71. Prenatal Development and Function of Human Mononuclear Phagocytes
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72. Overcoming the therapeutic resistance of hepatomas by targeting the tumor microenvironment
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73. Hepatitis C virus infects and perturbs liver stem cells
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74. Cell-type-focused compound screen in human organoids reveals CK1 inhibition protects cone photoreceptors from death
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75. Cancer research with a human touch
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76. Hepatocellular carcinoma: Prospects for natural killer cell immunotherapy
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77. Cancer patient-derived organoids: Novel models for the study of natural products
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78. Application and challenges of tumor organoid technology in precision immunotherapy
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79. Organoids as Model Systems to Investigate Circadian Clock-Related Diseases and Treatments
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80. Current trends and research topics regarding organoids: A bibliometric analysis of global research from 2000 to 2023
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81. Exploring tumor organoids for cancer treatment
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83. Exploring the effects of gut microbiota on cholangiocarcinoma progression by patient-derived organoids
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85. Application progress of bio-manufacturing technology in kidney organoids
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86. CRSP8-driven fatty acid metabolism reprogramming enhances hepatocellular carcinoma progression by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling
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87. Patient-derived organoids inform pharmacogenomic vulnerabilities in liver cancer
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88. Developments and Applications of Liver-on-a-Chip Technology—Current Status and Future Prospects
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90. Modeling colorectal cancers using multidimensional organoids
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91. Bioengineered Liver Models for Investigating Disease Pathogenesis and Regenerative Medicine
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94. Shell engineering in soft alginate‐based capsules for culturing liver spheroids
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95. The potential of patient-derived organoids in precision medicine of biliary tract cancer
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96. “Tissues in a Dish”: A Review of Organoids in Plastic Surgery
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97. Exposure of Human Skin Organoids to Low Genotoxic Stress Can Promote Epithelial-to-Mesenchymal Transition in Regenerating Keratinocyte Precursor Cells
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98. Academic collaborative models fostering the translation of physiological in vitro systems from basic research into drug discovery
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99. Hypomethylated RRBP1 Potentiates Tumor Malignancy and Chemoresistance in Upper Tract Urothelial Carcinoma
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100. Clinical value and influencing factors of establishing stomach cancer organoids by endoscopic biopsy
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