Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

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2. Modeling tumor development and metastasis using paired organoids derived from patients with colorectal cancer liver metastases
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3. Gastrointestinal cancer organoids—applications in basic and translational cancer research
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4. Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer
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5. Organoids and regenerative hepatology
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6. Papillary thyroid cancer organoids harboring BRAFV600E mutation reveal potentially beneficial effects of BRAF inhibitor-based combination therapies
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7. Establishment and Long-Term Expansion of Small Cell Lung Cancer Patient-Derived Tumor Organoids
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8. Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition
   van Tienderen, Gilles S, Rosmark, Oskar, Lieshout, Ruby, Willemse, Jorke, de Weijer, Floor, Elowsson Rendin, Linda, Westergren-Thorsson, Gunilla, Doukas, Michail, Groot Koerkamp, Bas, van Royen, Martin E et al. · 2023 · Acta Biomaterialia
9. Organoid Transplantation Can Improve Reproductive Prognosis by Promoting Endometrial Repair in Mice
   Huixing Zhang, Dabao Xu, Yan Li, Jianqiang Lan, Yu Zhu, Jia Cao, Mingyue Hu, Juanjuan Yuan, Jin Peng He, Gang Li et al. · 2022 · International Journal of Biological Sciences
10. Tumor decellularization reveals proteomic and mechanical characteristics of the extracellular matrix of primary liver cancer
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11. Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance
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12. Organoids‐On‐a‐Chip for Personalized Precision Medicine
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13. Precision models in hepatocellular carcinoma
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14. Non-animal models in dermatological research
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15. Single-Cell Resolution Three-Dimensional Imaging of Intact Organoids
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16. Organoid culture system for patient-derived lung metastatic osteosarcoma
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17. Evaluating the transcriptional fidelity of cancer models
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18. circKCNN2 suppresses the recurrence of hepatocellular carcinoma at least partially via regulating miR‐520c‐3p/methyl‐DNA‐binding domain protein 2 axis
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19. Organoids: A new approach in toxicity testing of nanotherapeutics
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20. Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine
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21. Reconstructing the tumor architecture into organoids
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22. Cholangiocarcinoma 2020: the next horizon in mechanisms and management
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23. Living biobank-based cancer organoids: prospects and challenges in cancer research
    Haixin Li, Hongkun Liu, Kexin Chen · 2022 · Cancer Biology and Medicine
24. Neoantigen cancer vaccines: a new star on the horizon
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25. Establishing Pure Cancer Organoid Cultures: Identification, Selection and Verification of Cancer Phenotypes and Genotypes
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26. 3D Cell Cultures as Prospective Models to Study Extracellular Vesicles in Cancer
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27. Organoid factory: The recent role of the human induced pluripotent stem cells (hiPSCs) in precision medicine
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28. Patient-Derived Bladder Cancer Organoid Models in Tumor Biology and Drug Testing: A Systematic Review
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29. A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens
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30. Technologies to Assess Drug Response and Heterogeneity in Patient-Derived Cancer Organoids
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31. Recent advances in organoid engineering: A comprehensive review
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32. Patient-derived organoid culture of gastric cancer for disease modeling and drug sensitivity testing
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33. Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro
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34. Dendritic Cell Responses and Function in Malaria
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35. Generation of 3D human gastrointestinal organoids: principle and applications
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36. Human liver model systems in a dish
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37. Amphiregulin promotes hair regeneration of skin‐derived precursors via the PI3K and MAPK pathways
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38. Patient-Derived Tumor Organoids: New Progress and Opportunities to Facilitate Precision Cancer Immunotherapy
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39. Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens
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40. Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology
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41. Gastric Organoids: Progress and Remaining Challenges
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42. 3D culture models to study pathophysiology of steatotic liver disease
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43. Models for Understanding Resistance to Chemotherapy in Liver Cancer
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44. Recreating Tumour Complexity in a Dish: Organoid Models to Study Liver Cancer Cells and their Extracellular Environment
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45. Extracellular Matrix-Based Hydrogels to Tailoring Tumor Organoids
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46. Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
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47. Patient-derived precision cut tissue slices from primary liver cancer as a potential platform for preclinical drug testing
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48. Organoid bioinks: construction and application
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49. Malignant ascites-derived organoid (MADO) cultures for gastric cancer in vitro modelling and drug screening
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50. Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens
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51. Breast cancer organoids derived from patients: A platform for tailored drug screening
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52. Emerging role of molecular diagnosis and personalized therapy for hepatocellular carcinoma
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54. Human-correlated genetic models identify precision therapy for liver cancer
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55. In Vitro Models of the Liver: Disease Modeling, Drug Discovery and Clinical Applications
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56. Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
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57. <i>In vitro</i> functional models for human liver diseases and drug screening: beyond animal testing
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58. Microfluidic Liver-on-a-Chip for Preclinical Drug Discovery
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59. Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells
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60. Molecular Targets in Cholangiocarcinoma
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61. hPSC-derived organoids: models of human development and disease
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62. Patient-Derived Tumor Organoids for Drug Repositioning in Cancer Care: A Promising Approach in the Era of Tailored Treatment
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63. Patient-Derived Cancer Organoids for Precision Oncology Treatment
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64. Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro
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65. A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer
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66. Three-dimensional culture models to study glioblastoma — current trends and future perspectives
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67. Integrative analysis of multiple genomic data from intrahepatic cholangiocarcinoma organoids enables tumor subtyping
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68. 3D bioprinted liver tissue and disease models: Current advances and future perspectives
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69. Organoids: opportunities and challenges of cancer therapy
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70. A Promising New Model: Establishment of Patient‐Derived Organoid Models Covering HPV‐Related Cervical Pre‐Cancerous Lesions and Their Cancers
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71. Biomaterial-assisted organoid technology for disease modeling and drug screening
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72. Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging
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73. Liver Cancer: Current and Future Trends Using Biomaterials
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74. Examining the gut-liver axis in liver cancer using organoid models
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75. Liver organoids: established tools for disease modeling and drug development
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76. Fourier light-field imaging of human organoids with a hybrid point-spread function
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77. Patient-derived Tumour Organoids: A Bridge between Cancer Biology and Personalised Therapy
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78. MAIT cells in liver inflammation and fibrosis
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79. SIRT1 in Secretory Organ Cancer
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80. Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer
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82. The integration of spheroids and organoids into organ-on-a-chip platforms for tumour research: A review
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83. Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner
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84. Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma
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85. Gene manipulation in liver ductal organoids by optimized recombinant adeno-associated virus vectors
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86. microRNAs as biomarkers of ovarian cancer
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87. Hepatocellular Carcinoma
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88. Liver spheroids on chips as emerging platforms for drug screening
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89. Precision Medicine for Hepatocellular Carcinoma: Clinical Perspective
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90. Decoding the basis of histological variation in human cancer
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91. Organoids Provide an Important Window on Inflammation in Cancer
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92. Three-Dimensional Organoids in Cancer Research: The Search for the Holy Grail of Preclinical Cancer Modeling
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93. Organoids: Past Learning and Future Directions
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94. The use of induced pluripotent stem cells in domestic animals: a narrative review
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95. Establishment and drug screening of patient-derived extrahepatic biliary tract carcinoma organoids
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96. Immuno-genomic classification of colorectal cancer organoids reveals cancer cells with intrinsic immunogenic properties associated with patient survival
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97. Decellularized normal and cancer tissues as tools for cancer research
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98. Patient-derived cancer models: Valuable platforms for anticancer drug testing
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99. Single-Cell Transcriptomics Reveals Heterogeneity and Drug Response of Human Colorectal Cancer Organoids
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100. The role of patient-derived ovarian cancer organoids in the study of PARP inhibitors sensitivity and resistance: from genomic analysis to functional testing
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