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Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
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Cites
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., et al. (1998) · Nature · doi:10.1038/31159 · Cited by 7,847
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages
Schnappinger, D., Ehrt, S., Voskuil, M. I., Liu, Y., Mangan, J. A., Monahan, I. M., Dolganov, G., Efron, B., Butcher, P. D., Nathan, C., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030846 · Cited by 1,420
The glyoxylate cycle is required for fungal virulence
Lorenz, M. C., & Fink, G. R. (2001) · Nature · doi:10.1038/35083594 · Cited by 745
Tuberculosis — metabolism and respiration in the absence of growth
Boshoff, H. I. M., & Barry, C. E. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1065 · Cited by 448
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Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
Michelucci, A., Cordes, T., Ghelfi, J., Pailot, A., Reiling, N., Goldmann, O., Binz, T., Wegner, A., Tallam, A., Rausell, A., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1218599110 · Cited by 1,191
Mycobacterial persistence requires the utilization of host cholesterol
Pandey, A. K., & Sassetti, C. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711159105 · Cited by 1,064
Griffin, J. E., Gawronski, J. D., DeJesus, M. A., Ioerger, T. R., Akerley, B. J., & Sassetti, C. M. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002251 · Cited by 1,048
DeJesus, M. A., Gerrick, E. R., Xu, W., Park, S. W., Long, J. E., Boutte, C. C., Rubin, E. J., Schnappinger, D., Ehrt, S., Fortune, S. M., et al. (2017) · mBio · doi:10.1128/mbio.02133-16 · Cited by 668
Daniel, J., Maamar, H., Deb, C., Sirakova, T. D., & Kolattukudy, P. E. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002093 · Cited by 608
Intracellular Mycobacterium tuberculosis Exploits Host-derived Fatty Acids to Limit Metabolic Stress
Lee, W., VanderVen, B. C., Fahey, R. J., & Russell, D. G. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.445056 · Cited by 424
Stinear, T. P., Seemann, T., Pidot, S., Frigui, W., Reysset, G., Garnier, T., Meurice, G., Simon, D., Bouchier, C., Ma, L., et al. (2007) · Genome Research · doi:10.1101/gr.5942807 · Cited by 396
Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis
Koul, A., Vranckx, L., Dendouga, N., Balemans, W., Van den Wyngaert, I., Vergauwen, K., Göhlmann, H. W. H., Willebrords, R., Poncelet, A., Guillemont, J., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803899200 · Cited by 364
Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
Zhang, Y. J., Reddy, M. C., Ioerger, T. R., Rothchild, A. C., Dartois, V., Schuster, B. M., Trauner, A., Wallis, D., Galaviz, S., Huttenhower, C., et al. (2013) · Cell · doi:10.1016/j.cell.2013.10.045 · Cited by 351
“Mtb in particular relies upon cholesterol and fatty acid catabolism, gluconeogenesis, and the glyoxylate shunt to survive the host environment (Lee et al., 2013; Marrero et al., 2010; McKinney et al., 2000; Muñoz-Elı́as and McKinney, 2005; Pandey and Sassetti, 2008).”
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
Ouimet, M., Koster, S., Sakowski, E., Ramkhelawon, B., van Solingen, C., Oldebeken, S., Karunakaran, D., Portal-Celhay, C., Sheedy, F. J., Ray, T. D., et al. (2016) · Nature Immunology · doi:10.1038/ni.3434 · Cited by 361
Muñoz‐Elías, E. J., Upton, A. M., Cherian, J., & McKinney, J. D. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05155.x · Cited by 359
Self-citationMajor roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis
Dunn, M. F., Ramírez-Trujillo, J. A., & Hernández-Lucas, I. (2009) · Microbiology · doi:10.1099/mic.0.030858-0 · Cited by 304
Eoh, H., & Rhee, K. Y. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219375110 · Cited by 278
Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection
Nair, S., Huynh, J. P., Lampropoulou, V., Loginicheva, E., Esaulova, E., Gounder, A. P., Boon, A. C. M., Schwarzkopf, E. A., Bradstreet, T. R., Edelson, B. T., et al. (2018) · Journal of Experimental Medicine · doi:10.1084/jem.20180118 · Cited by 280
1H NMR-based Metabolomic Profiling in Mice Infected with Mycobacterium tuberculosis
Shin, J.-H., Yang, J.-Y., Jeon, B.-Y., Yoon, Y. J., Cho, S.-N., Kang, Y.-H., Ryu, D. H., & Hwang, G.-S. (2011) · Journal of Proteome Research · doi:10.1021/pr101054m · Cited by 247
A central role for the peroxisomal membrane in glyoxylate cycle function
Kunze, M., Pracharoenwattana, I., Smith, S. M., & Hartig, A. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.09.009 · Cited by 211
Schubert, O. T., Ludwig, C., Kogadeeva, M., Zimmermann, M., Rosenberger, G., Gengenbacher, M., Gillet, L. C., Collins, B. C., Röst, H. L., Kaufmann, S. H. E., et al. (2015) · Cell Host & Microbe · doi:10.1016/j.chom.2015.06.001 · Cited by 211
Singh, A., Guidry, L., Narasimhulu, K. V., Mai, D., Trombley, J., Redding, K. E., Giles, G. I., Lancaster, J. R., & Steyn, A. J. C. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700490104 · Cited by 194
Baker, J. J., Johnson, B. K., & Abramovitch, R. B. (2014) · Molecular Microbiology · doi:10.1111/mmi.12688 · Cited by 181
The glyoxylate shunt, 60 years on
Dolan, S. K., & Welch, M. (2018) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090817-062257 · Cited by 180
Ramírez, M. A., & Lorenz, M. C. (2007) · Eukaryotic Cell · doi:10.1128/ec.00372-06 · Cited by 174
Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense
Luan, H. H., & Medzhitov, R. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.08.013 · Cited by 130
Xie, L., Liu, W., Li, Q., Chen, S., Xu, M., Huang, Q., Zeng, J., Zhou, M., & Xie, J. (2015) · Journal of Proteome Research · doi:10.1021/pr500859a · Cited by 128
A nutritive view on the host–pathogen interplay
Schaible, U. E., & Kaufmann, S. H. E. (2005) · Trends in Microbiology · doi:10.1016/j.tim.2005.06.009 · Cited by 106
Redox Biology of Tuberculosis Pathogenesis
Trivedi, A., Singh, N., Bhat, S. A., Gupta, P., & Kumar, A. (2012) · Advances in Microbial Physiology · doi:10.1016/b978-0-12-398264-3.00004-8 · Cited by 88
Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M., et al. (2016) · PLOS Pathogens · doi:10.1371/journal.ppat.1005566 · Cited by 81
Puckett, S., Trujillo, C., Eoh, H., Marrero, J., Spencer, J., Jackson, M., Schnappinger, D., Rhee, K., & Ehrt, S. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004144 · Cited by 72
The Transcription Factor Homolog CTF1 Regulates β-Oxidation in Candida albicans
Ramírez, M. A., & Lorenz, M. C. (2009) · Eukaryotic Cell · doi:10.1128/ec.00206-09 · Cited by 67
Chew, S. Y., Ho, K. L., Cheah, Y. K., Ng, T. S., Sandai, D., Brown, A. J. P., & Than, L. T. L. (2019) · Scientific Reports · doi:10.1038/s41598-019-39117-1 · Cited by 49
Adolph, C., McNeil, M. B., & Cook, G. M. (2022) · mBio · doi:10.1128/mbio.01672-22 · Cited by 32
Metadata
- Authors
- Muñoz-Elías, E. J., & McKinney, J. D.
- Venue
- Nature Medicine
- Published
- 2005-05-15
- Volume
- 11
- Issue
- 6
- Pages
- 638-644
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2053867514
- Cited by
- 756
- References
- 4
- FWCI
- 24.21
- Type
- journal article
- Language
- en
- Open access
- green
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