Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Hilton, Matthew J, Tu, Xiaolin, Wu, Ximei, Bai, Shuting, Zhao, Haibo, Kobayashi, Tatsuya, Kronenberg, Henry M, Teitelbaum, Steven L +3 more·2008·Nature Medicine

Cited by (600)

Items 301–400 of 600

  1. Non-canonical Wnt signaling participates in Jagged1-induced osteo/odontogenic differentiation in human dental pulp stem cells
    Chatvadee Kornsuthisopon, Ajjima Chansaenroj, Jeeranan Manokawinchoke, Kevin A. Tompkins, Nopadon Pirarat, Thanaphum Osathanon · 2022 · Scientific Reports
  2. Calcium/calmodulin-dependent protein kinase IV (CaMKIV) enhances osteoclast differentiation via the up-regulation of Notch1 protein stability
    Yun-Hee Choi, Eun‐Jung Ann, Ji‐Hye Yoon, Jung‐Soon Mo, Mi‐Yeon Kim, Hee-Sae Park · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  3. Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged–Notch signaling in fin and limb development
    Jing Tian, Jinhui Shao, Cong Liu, Hsin-Yu Hou, Chih-Wei Chou, Mohammad Shboul, Guoqing Li, Mohammad S. El-Khateeb, Omar Q. Samarah, Yao Kou et al. · 2018 · Cellular and Molecular Life Sciences
  4. Communication between endothelial cells and osteoblasts in regulation of bone homeostasis: Notch players
    Daria A. Perepletchikova, Anna Malashicheva · 2025 · Stem Cell Research & Therapy
  5. Emerin suppresses Notch signaling by restricting the Notch intracellular domain to the nuclear membrane
    Byongsun Lee, Tae-Hee Lee, Jaekyung Shim · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  6. Glucocorticoids inhibit notch target gene expression in osteoblasts
    Stefano Zanotti, Jungeun Yu, Suyash Adhikari, ERNESTO M. CANALIS · 2018 · Journal of Cellular Biochemistry
  7. TRIM2 regulates the development and metastasis of tumorous cells of osteosarcoma
    Yi Qin, Jichao� Ye, Fulan Zhao, Shaoyu Hu, Suwei Wang · 2018 · International Journal of Oncology
  8. Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation
    Cuicui Wang, Jie Shen, Kiminori Yukata, Jason A. Inzana, Regis J. O’Keefe, Hani A. Awad, Matthew J. Hilton · 2014 · Bone
  9. Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signaling
    Daria A. Perepletchikova, Polina D. Kuchur, Liubov Basovich, Irina Khvorova, Arseniy A. Lobov, Kseniia Azarkina, Nikolay Aksenov, Светлана Анатольевна Божкова, Vitaliy V. Karelkin, Anna Malashicheva · 2025 · Cell Communication and Signaling
  10. Tissue-Specific Cultured Human Pericytes: Perivascular Cells from Smooth Muscle Tissue Have Restricted Mesodermal Differentiation Ability
    Enrico Pierantozzi, Bianca Vezzani, Margherita Badin, Carlo Curina, Filiberto Maria Severi, Felice Petraglia, Davide Randazzo, Daniela Rossi, Vincenzo Sorrentino · 2016 · Stem Cells and Development
  11. Loss of Notch3 Signaling Enhances Osteogenesis of Mesenchymal Stem Cells from Mandibular Torus
    Xiaowei Dou, Wonse Park, S. Lee, Q.Z. Zhang, Lee Carrasco, Anh D. Le · 2016 · Journal of Dental Research
  12. Revisiting the Mesenchymal “Stem vs. Stromal” Cell Dichotomy and Its Implications for Development of Improved Potency Metrics
    Donald G. Phinney, Ryang Hwa Lee, Siddaraju V. Boregowda · 2023 · Stem Cells
  13. MAML1 Enhances the Transcriptional Activity of Runx2 and Plays a Role in Bone Development
    Takashi Watanabe, Toshinao Oyama, Maki Asada, Daisuke Harada, Yoshiaki Ito, Masayo Inagawa, Yutaka Suzuki, Sumio Sugano, Ken‐ichi Katsube, Gérard Karsenty et al. · 2013 · PLoS Genetics
  14. Notch signaling pathways in human thoracic ossification of the ligamentum flavum
    Xiaochen Qu, Zhongqiang Chen, Dongwei Fan, Chuiguo Sun, Yan Zeng, Xiaofei Hou, Shanglong Ning · 2016 · Journal of Orthopaedic Research®
  15. Maintenance of Bone Homeostasis by DLL1‐Mediated Notch Signaling
    Yukari Muguruma, Katsuto Hozumi, Hiroyuki Warita, Takashi Yahata, Tomoko Uno, Mamoru Ito, Kiyoshi Ando · 2016 · Journal of Cellular Physiology
  16. Influence of olive oil and its components on mesenchymal stem cell biology
    Antonio Casado‐Díaz, Gabriel Dorado, José Manuel Quesada‐Gómez · 2019 · World Journal of Stem Cells
  17. Implication of the p53-Related miR-34c, -125b, and -203 in the Osteoblastic Differentiation and the Malignant Transformation of Bone Sarcomas
    Camille Jacques, Robel A. Tesfaye, Mélanie Lavaud, Steven Georges, Marc Baud’huin, François Lamoureux, Benjamin Ory · 2020 · Cells
  18. Silk fibroin as a potential candidate for bone tissue engineering applications
    Shaohao Quan, Jie Yang, Sirui Huang, Jundong Shao, Yang Liu, Hui Yang · 2024 · Biomaterials Science
  19. Bone Development and Remodeling
    Christa Maes, Henry M. Kronenberg · 2015 · Elsevier eBooks
  20. The Proteasome and Myeloma-Associated Bone Disease
    Fabrizio Accardi, Denise Toscani, Federica Costa, Franco Aversa, Nicola Giuliani · 2017 · Calcified Tissue International
  21. Designing Biomaterials to Modulate Notch Signaling in Tissue Engineering and Regenerative Medicine
    Kathleen Zohorsky, Kibret Mequanint · 2020 · Tissue Engineering Part B Reviews
  22. Tumor–Stroma Interactions in Bone Metastasis: Molecular Mechanisms and Therapeutic Implications
    Hanqiu Zheng, Wenyang Li, Yibin Kang · 2016 · Cold Spring Harbor Symposia on Quantitative Biology
  23. DNA methylation of RUNX3 promotes the progression of gallbladder cancer through repressing SLC7A11-mediated ferroptosis
    Chen Cai, Yidi Zhu, Jiasheng Mu, Shilei Liu, Ziyi Yang, Zi-you Wu, Cheng Zhao, Xiaoling Song, Yuanyuan Ye, Jun Gu et al. · 2023 · Cellular Signalling
  24. HEY1-NCOA2 expression modulates chondrogenic differentiation and induces mesenchymal chondrosarcoma in mice
    Miwa Tanaka, Mizuki Homme, Yasuyo Teramura, Kohei Kumegawa, Yukari Yamazaki, Kyoko Yamashita, Motomi Osato, Reo Maruyama, Takuro Nakamura · 2023 · JCI Insight
  25. Nanofiber-induced hierarchically-porous magnesium phosphate bone cements accelerate bone regeneration by inhibiting Notch signaling
    Jingteng Chen, Ling Dan Yu, Tian Gao, Xiangyang Dong, Shiyu Li, Yinchu Liu, Jian Yang, Kezhou Xia, Yaru Yu, Y K Li et al. · 2024 · Bioactive Materials
  26. Silk peptides inhibit adipocyte differentiation through modulation of the Notch pathway in C3H10T1/2 cells
    So-Ra Jung, No‐Joon Song, Hyun Sook Hwang, Jae Jin An, Yong‐Jun Cho, Hae Young Kweon, Seok-Woo Kang, Kwang Gill Lee, Keejung Yoon, Byung-Joon Kim et al. · 2011 · Nutrition Research
  27. Inhibition of heat shock protein 90 rescues glucocorticoid-induced bone loss through enhancing bone formation
    Haixiao Chen, Xing Ji, Xinhua Hu, Lihua Chen, Haiyan Lv, Chengyun Xu, Dun Hong, Ximei Wu · 2017 · The Journal of Steroid Biochemistry and Molecular Biology
  28. Reverse engineering development: Crosstalk opportunities between developmental biology and tissue engineering
    Ralph Marcucio, Ling Qin, Eben Alsberg, Joel D. Boerckel · 2017 · Journal of Orthopaedic Research®
  29. Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression
    Nan Wang, Wei Liu, Tao Tan, Chaoqun Dong, Duanyang Lin, Jun Zhao, Chang Yu, Xiaoji Luo · 2017 · Oncotarget
  30. Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway
    Jun Ying, Taotao Xu, Cuicui Wang, Hongting Jin, Peijian Tong, Jianjun Guan, Yousef Abu‐Amer, Regis J. O’Keefe, Jie Shen · 2020 · JCI Insight
  31. Hey Factors at the Crossroad of Tumorigenesis and Clinical Therapeutic Modulation of Hey for Anticancer Treatment
    Zihao Liu, Andrew James Sanders, Gehao Liang, Erwei Song, Wen G. Jiang, Chang Gong · 2017 · Molecular Cancer Therapeutics
  32. Insights into the Notch signaling pathway in degenerative musculoskeletal disorders: Mechanisms and perspectives
    Gaoming Liu, Jun Wei, Wenfeng Xiao, Wenqing Xie, Qin Ru, Lin Chen, Yuxiang Wu, Ali Mobasheri, Yusheng Li · 2023 · Biomedicine & Pharmacotherapy
  33. Bisphosphonate therapy for spinal osteoporosis in Hajdu-Cheney syndrome – new data and literature review
    James F. H. Pittaway, Christopher Harrison, Yumie Rhee, Muriel Holder‐Espinasse, Alan E Fryer, Tim Cundy, William Martin Drake, Melita D. Irving · 2018 · Orphanet Journal of Rare Diseases
  34. Notch Signaling and Development of the Hematopoietic System
    Ashley R. Sandy, Morgan Jones, Ivan P. Maillard · 2012 · Advances in experimental medicine and biology
  35. MicroRNAs in bone development and their diagnostic and therapeutic potentials in osteoporosis
    Supaporn Suttamanatwong · 2016 · Connective Tissue Research
  36. Notch Signaling in Mesenchymal Stem Cells Harvested From Geriatric Mice
    Patricia L. Mutyaba, Nicole S. Belkin, Luke A. Lopas, Chancellor F. Gray, Derek Dopkin, Kurt David Hankenson, Jaimo Ahn · 2014 · Journal of Orthopaedic Trauma
  37. RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival
    Toshifumi Fujiwara, Jian Ping Zhou, Shiqiao Ye, Haibo Zhao · 2016 · Cell Death and Disease
  38. Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression
    Yukio Sato, Yo Mabuchi, Ken‐ichi Miyamoto, Daisuke Araki, Kunimichi Niibe, Diarmaid D. Houlihan, Satoru Morikawa, Taneaki Nakagawa, Toshihiro Nakajima, Chihiro Akazawa et al. · 2016 · PLoS ONE
  39. Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma
    Qingxia Wei, Yuning J. Tang, Véronique Voisin, Shingo Sato, Makoto Hirata, Heather Whetstone, Ilkyu Han, Laurie Ailles, Gary D. Bader, Jay Steven Wunder et al. · 2015 · Oncotarget
  40. Expression of TLE3 by bone marrow stromal cells is regulated by canonical Wnt signaling
    Shoichiro Kokabu, Tsuyoshi Sato, Satoshi Ohte, Yuichiro Enoki, Masahiko Okubo, Naoki Hayashi, Junya Nojima, Sho Tsukamoto, Yosuke Fukushima, Yasuaki Sakata et al. · 2014 · FEBS Letters
  41. miRNAs in Bone Development
    Garyfallia Papaioannou · 2015 · Current Genomics
  42. Hematopoietic Stem Cells, Their Niche, and the Concept of Co-Culture Systems: A Critical Review.
    Anuradha Vaidya, Vaijayanti Kale · 2015 · PubMed
  43. Lenalidomide restores the osteogenic differentiation of bone marrow mesenchymal stem cells from multiple myeloma patients via deactivating Notch signaling pathway
    Juan Guo, Chengming Fei, Youshan Zhao, Sida Zhao, Qingqing Zheng, Jiying Su, Dong Wu, Xiao Li, Chunkang Chang · 2017 · Oncotarget
  44. The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking
    Bo Li, Chouin Wong, Shihong Max Gao, Rulan Zhang, Rongbo Sun, Yulong Li, Yan Song · 2018 · eLife
  45. Transduction of Oct6 or Oct9 gene concomitant with Myc family gene induced osteoblast-like phenotypic conversion in normal human fibroblasts
    Naoki Mizoshiri, T Kishida, Kenta Yamamoto, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Yuki Mori, Akika Ejima, Yasushi Sato, Yuji Arai et al. · 2015 · Biochemical and Biophysical Research Communications
  46. Effects of γ-secretase inhibition on the proliferation and vitamin D3 induced osteogenesis in adipose derived stem cells
    Wei Jing, Zhonghua Xiong, Xiaoxiao Cai, Yuanding Huang, Xiaoyu Li, Xingmei Yang, Lei Liu, Wei Dong Tang, Yunfeng Lin, Weidong Tian · 2010 · Biochemical and Biophysical Research Communications
  47. Gene expression profiles and bioinformatics analysis of insulin‐like growth factor‐1 promotion of osteogenic differentiation
    Yuan, Yashuai, Duan, Ruimeng, Wu, Baolin, Huang, Wei, Zhang, Xiuzhi, Qu, Mingjia, Liu, Tao, Yu, Xiaobing · 2019 · Molecular Genetics & Genomic Medicine
  48. Murine models of osteosarcoma: A piece of the translational puzzle
    Mannu Walia, Wilson Castillo‐Tandazo, Anthony J. Mutsaers, Thomas John Martin, Carl R. Walkley · 2017 · Journal of Cellular Biochemistry
  49. Enhanced osteogenesis of mesenchymal stem cells encapsulated in injectable microporous hydrogel
    Seth Edwards, Mrinal Ganash, Ziqiang Guan, Jeil Lee, Young Jo Kim, Kyung Jae Jeong · 2024 · Scientific Reports
  50. Notch Signaling and the Developing Skeleton
    Timothy J. Mead, Katherine E. Yutzey · 2012 · Advances in experimental medicine and biology
  51. HES1 inhibits adipogenesis of porcine mesenchymal stem cells via transcriptional repression of FAD24
    T. Lei, Y. Bi, Min Gao, Shenghua Gao, Lulu Zhou, Hailiang Zheng, Xiaodong Chen · 2013 · Domestic Animal Endocrinology
  52. MicroRNA-23a-5p regulates osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting mitogen-activated protein kinase-13
    Gang Ren, Jing Sun, Meng‐Meng Li, Yong‑Dong Zhang, Rong‑Hua Li, Yu‑Ming Li · 2018 · Molecular Medicine Reports
  53. Noncoding RNAs in Calcific Aortic Valve Disease: A Review of Recent Studies
    Wen-Juan Ni, Ying-Zhong Wu, Dong-Hong Ma, Xiao-Min Leng · 2018 · Journal of Cardiovascular Pharmacology
  54. Physical Activity and Post-Transcriptional Regulation of Aging Decay: Modulation of Pathways in Postmenopausal Osteoporosis
    Federica Vita, Sebastiano Gangemi, Giovanni Pioggia, Fabio Trimarchi, Debora Di Mauro · 2022 · Medicina
  55. Calcific and Degenerative Heart Valve Disease
    Elena Rabkin Aikawa, Frederick J. Schöen · 2014 · Elsevier eBooks
  56. Overexpression of Jagged-1 and Its Intracellular Domain in Human Mesenchymal Stromal Cells Differentially Affect the Interaction with Hematopoietic Stem and Progenitor Cells
    Regina Duryagina, Sebastian Thieme, Konstantinos Anastassiadis, Carsten Werner, Susan Schneider, Manja Wobus, Sebastian Brenner, Martin Bornhäuser · 2013 · Stem Cells and Development
  57. Short Anabolic Peptides for Bone Growth
    Zaid Amso, Jillian Cornish, Margaret Anne Brimble · 2016 · Medicinal Research Reviews
  58. Mesenchymal Stem Cells Differentiation: Mitochondria Matter in Osteogenesis or Adipogenesis Direction
    Kun Ji, Ling Ding, Xi Chen, Yun Dai, Fangfang Sun, Guofeng Wu, Lu Wei · 2020 · Current Stem Cell Research & Therapy
  59. Comprehensive Analysis of RUNX and TGF-β Mediated Regulation of Immune Cell Infiltration in Breast Cancer
    Liang Gao, Fangfang Zhou · 2021 · Frontiers in Cell and Developmental Biology
  60. NOTCH Signaling in Osteosarcoma
    Zhenghao Zhang, Wei Wu, Zengwu Shao · 2023 · Current Issues in Molecular Biology
  61. Notch Signaling Regulates the Chondrogenic Potential of Both Articular Chondrocytes and Their Progenitors During Expansion
    Anastasiia D. Kurenkova, Lei Li, Anna P Usanova, Xiaogang Feng, Baoyi Zhou, Andrey Anatolevich Nedorubov, Alexey Vladimirovich Lychagin, Andrei S. Chagin · 2023 · Stem Cells
  62. The Involvement of microRNAs in Bone Remodeling Signaling Pathways and Their Role in the Development of Osteoporosis
    Rogelio Frank Jiménez-Ortega, Alejandra Isabel Ortega-Meléndez, Nelly Patiño, Berenice Rivera‐Paredez, Alberto Hidalgo‐Bravo, Rafael Velázquez‐Cruz · 2024 · Biology
  63. Hairy and Enhancer of Split-related with YRPW Motif (HEY)2 Regulates Bone Remodeling in Mice
    Stefano Zanotti, ERNESTO M. CANALIS · 2013 · Journal of Biological Chemistry
  64. Transgenic PDGF-BB sericin hydrogel potentiates bone regeneration of BMP9-stimulated mesenchymal stem cells through a crosstalk of the Smad-STAT pathways
    Huijie Zhang, Fu‐Shu Li, Feng Wang, Han Wang, Tong‐Chuan He, Russell R. Reid, Bai‐Cheng He, Qingyou Xia · 2022 · Regenerative Biomaterials
  65. Aseptic Loosening of Total Hip Arthroplasty as a Result of Local Failure of Tissue Homeostasis
    Jiří Gallo, Yrj T., B. Stuart, P Jacob, Emmanuel Gibon, Jukka Pajarinen, Yuya Takakubo, Peter C. Schalock, Zygmunt Mackiewicz, Eemeli Jämsen et al. · 2012 · InTech eBooks
  66. 3D-printed advanced scaffold armed with exosomes derived from human skeletal stem cell identified by single-cell RNA sequencing enhances osteochondral regeneration
    Wenqiang Lou, Xinzhu Qiu, Yiming Qin, Yingnan Lu, Yong Bing Cao, Hongbin Lü · 2025 · Bioactive Materials
  67. Benefits of biphasic calcium phosphate hybrid scaffold-driven osteogenic differentiation of mesenchymal stem cells through upregulated leptin receptor expression
    Chi‐Chien Niu, Song‐Shu Lin, Wen‐Jer Chen, Shih‐Jung Liu, Lih-Huei Chen, Chuen-Yung Yang, Chao‐Jan Wang, Li‐Jen Yuan, Po‐Han Chen, Hsiao-Yang Cheng · 2015 · Journal of Orthopaedic Surgery and Research
  68. Bone marrow mesenchymal stem cell‐derived exosomes reduce insulin resistance and obesity in mice via the PI3K / AKT signaling pathway
    Hongwei Shi, Xiaojing Hao, Yaqin Sun, Huilin Zhang, Yating Zhao, Bin Wang, Jiayin Lu, Wei Hou, Yi Lin Yan, Xiuju Yu et al. · 2023 · FEBS Open Bio
  69. Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development
    Yuki Matsushita, Hiroaki Manabe, Takahiro Ohyama, Shogo Nakamura, Mizuki Nagata, Wanida Ono, Noriaki Ono · 2023 · Journal of Biological Chemistry
  70. Sustained notch signaling inhibition with a gamma-secretase inhibitor prevents traumatic heterotopic ossification
    Zheng Wang, Xinzeyu Yi, Chao Jian, Baiwen Qi, Qiaoyun Liu, Zonghuan Li, Aixi Yu · 2023 · Journal of Orthopaedic Translation
  71. Future Perspectives: Therapeutic Targeting of Notch Signalling May Become a Strategy in Patients Receiving Stem Cell Transplantation for Hematologic Malignancies
    Elisabeth Ersvær, Kimberley Joanne Hatfield, Håkon Reikvam, Øystein Bruserud · 2010 · Bone Marrow Research
  72. The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α
    Jungeun Yu, ERNESTO M. CANALIS · 2019 · Journal of Biological Chemistry
  73. Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced osteogenic differentiation by targeting the proliferation of mesenchymal stem cells (MSCs)
    Ruidong Li, Wenwen Zhang, Zhengjian Yan, Wei Liu, Jiaming Fan, Yixiao Feng, Zongyue Zeng, Daigui Cao, Rex C. Haydon, Hue H. Luu et al. · 2021 · Aging
  74. Functions of the SNAI family in chondrocyte‐to‐osteocyte development
    Ehsan Razmara, Amirreza Bitaraf, Behnaz Karimi, Sadegh Babashah · 2021 · Annals of the New York Academy of Sciences
  75. Notch signaling: mediator and therapeutic target of bone metastasis
    Nilay S. Sethi, Yibin Kang · 2012 · BoneKEy Reports
  76. γ‐Secretase inhibitor reverts the Notch signaling attenuation of osteogenic differentiation in aged bone marrow mesenchymal stem cells
    Zhao-Long Tang, Junjun Wei, Yunbo Yu, Jiankang Zhang, Lei Liu, Wei Dong Tang, Jie Long, Xiaohui Zheng, Wei Jing · 2016 · Cell Biology International
  77. Skeletal Morphogenesis and Embryonic Development
    Yingzi Yang · 2013 · Wiley eBooks
  78. Indoxyl Sulfate-induced Vascular Calcification is mediated through Altered Notch Signaling Pathway in Vascular Smooth Muscle Cells
    Kazutoshi Yamaguchi, Maimaiti Yisireyili, Sumie Goto, Katsuhiro Kato, Xian Wu Cheng, Takayuki Nakayama, Tadashi Matsushita, Toshimitsu Niwa, Toyoaki Murohara, Kyosuke Takeshita · 2020 · International Journal of Medical Sciences
  79. Osteolineage depletion of mitofusin2 enhances cortical bone formation in female mice
    Allahdad Zarei, Anna Ballard, Linda Cox, Peter O. Bayguinov, Taylor L. Harris, Jennifer L. Davis, Philip M. Roper, James A. J. Fitzpatrick, Roberta Faccio, Deborah V. Novack · 2021 · Bone
  80. Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study
    Jia Tan, Jiaxin Li, Bojun Cao, Junxiang Wu, Dinghao Luo, Zhaoyang Ran, Liang Deng, Xiaoping Li, Wenbo Jiang, Kai Xie et al. · 2022 · Journal of Orthopaedic Translation
  81. Notch-Hes pathway mediates the impaired osteogenic differentiation of bone marrow mesenchymal stromal cells from myelodysplastic syndromes patients through the down-regulation of Runx2.
    Chengming Fei, Juan Guo, Youshan Zhao, Shucheng Gu, Sida Zhao, Xiao Li, Chunkang Chang · 2015 · Europe PMC (PubMed Central)
  82. Expression of the ectodomain‐releasing protease ADAM17 is directly regulated by the osteosarcoma and bone‐related transcription factor RUNX2
    Héctor Araya, Hugo Sepúlveda, Carlos O. Lizama, Oscar A. Vega, Sofía Jerez, Pedro Briceño, Roman Thaler, Scott M. Riester, Marcelo Antonelli, Flavio Salazar‐Onfray et al. · 2018 · Journal of Cellular Biochemistry
  83. Molecular Genetics of Cleidocranial Dysplasia
    Jamshid Motaei, Arash Salmaninejad, Ebrahim Jamali, Imaneh Khorsand, Mohammad Ahmadvand, Sasan Shabani, Farshid Karimi, Mohammad Sadegh Nazari, Golsa Ketabchi, Fatemeh Naqipour · 2020 · Fetal and Pediatric Pathology
  84. Distinct severity of phenotype in Hajdu-Cheney syndrome: a case report and literature review
    Chunhua Zeng, Yunting Lin, Zhikun Lu, Zhen Chen, Xiaoling Jiang, Xiaojian Mao, Zongcai Liu, Xinshuo Lu, Kangdi Zhang, Qiaoli Yu et al. · 2020 · BMC Musculoskeletal Disorders
  85. MACF1 alleviates aging‐related osteoporosis via HES1
    Chong Yin, Ye Edward Tian, Lifang Hu, Yang Yu, Zixiang Wu, Yan Zhang, Xue Wang, Zhiping Miao, Airong Qian · 2021 · Journal of Cellular and Molecular Medicine
  86. Development of the Skeleton
    Sylvain Provot, Ernestina Schipani, Joy Y. Wu, Henry M. Kronenberg · 2013 · Elsevier eBooks
  87. MTA‐induced Notch activation enhances the proliferation of human dental pulp cells by inhibiting autophagic flux
    Wei Qiu, Bing Sun, Fei He, Yaou Zhang · 2017 · International Endodontic Journal
  88. Effects of panax notoginseng saponins on the osteogenic differentiation of rabbit bone mesenchymal stem cells through TGF-β1 signaling pathway
    Yan Wang, Xuanping Huang, Yiyao Tang, Haiyun Lin, Nuo Zhou · 2016 · BMC Complementary and Alternative Medicine
  89. Cysteamine affects skeletal development and impairs motor behavior in zebrafish
    Chao Chen, Yongliang Zheng, Xue Li, Li Zhang, Kangyu Liu, Sujie Sun, Zilin Zhong, Hongmei Hu, Fasheng Liu, Guanghua Xiong et al. · 2022 · Frontiers in Pharmacology
  90. Integrated single-cell and bulk RNA sequencing analysis identified pyroptosis-related signature for diagnosis and prognosis in osteoarthritis
    Yanzhong Chen, Yaonan Zhang, Yongwei Ge, Hong Ren · 2023 · Scientific Reports
  91. Clinical and Genetic Correlation in Neurocristopathies: Bridging a Precision Medicine Gap
    Despoina Chatzi, Stella Aikaterini Kyriakoudi, Iasonas Dermitzakis, Maria Eleni Μanthou, Soultana Meditskou, Paschalis Theotokis · 2024 · Journal of Clinical Medicine
  92. Endothelial to mesenchymal Notch signaling regulates skeletal repair
    Sanja Novak, Hitoshi Tanigawa, Vijender Singh, Sierra Hope Root, Tannin A. Schmidt, Kurt David Hankenson, Ivo Kalajzić · 2024 · JCI Insight
  93. Use of Hes1 -GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation
    Hengwei Zhang, Wen Sheng Sun, Xing Li, Mengmeng Wang, Brendan F. Boyce, Matthew J. Hilton, Lianping Xing · 2016 · Bone
  94. γ‐Secretase‐dependent cleavage of amyloid precursor protein regulates osteoblast behavior
    Jane McLeod, Neil Curtis, Huw D. Lewis, Mark A. Good, Michael J. Fagan, Paul G. Genever · 2009 · The FASEB Journal
  95. The critical and specific transcriptional regulator of the microenvironmental niche for hematopoietic stem and progenitor cells
    Yoshiki Omatsu, Takashi Nagasawa · 2015 · Current Opinion in Hematology
  96. Prolonged Expansion Induces Spontaneous Neural Progenitor Differentiation from Human Gingiva-Derived Mesenchymal Stem Cells
    Thangavelu Soundara Rajan, Domenico Scionti, Francesca Diomede, Adriano Piattelli, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani · 2017 · Cellular Reprogramming
  97. Notch3 is involved in adipogenesis of human adipose-derived stromal/stem cells
    Demi A. Sandel, Mengcheng Liu, Ngozi Ogbonnaya, Jamie J. Newman · 2018 · Biochimie
  98. Functionalization of Silk Fibers by PDGF and Bioceramics for Bone Tissue Regeneration
    Michael Wöltje, Ronny Brünler, Melanie Böbel, Sabrina Ernst, Sabine Neuß, Dilbar Aibibu, Chokri Cherif · 2019 · Coatings
  99. Review of the Pathways Involved in the Osteogenic Differentiation of Adipose-Derived Stem Cells
    Derek B. Asserson, Hakan Orbay, David E. Sahar · 2019 · Journal of Craniofacial Surgery
  100. Disruption of the transcription factor RBP-J results in osteopenia attributable to attenuated osteoclast differentiation
    Jing Ma, Yali Liu, Yiyang Hu, Yaning Wei, Xingcheng Zhao, Guang‐Ying Dong, Hong‐Yan Qin, Yin Ding, Hua Han · 2012 · Molecular Biology Reports