TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4

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CTLA-4 can function as a negative regulator of T cell activation

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Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

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B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

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Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β

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A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells.

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice.

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CD4+CD25+ Regulatory T Cells Can Mediate Suppressor Function in the Absence of Transforming Growth Factor β1 Production and Responsiveness

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Inhibition of Transforming Growth Factor-β Signaling Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Mice

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Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

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Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

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CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

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CD28/B7 Regulation of Th1 and Th2 Subsets in the Development of Autoimmune Diabetes

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The Subpopulation of CD4+CD25+ Splenocytes That Delays Adoptive Transfer of Diabetes Expresses L-Selectin and High Levels of CCR7

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Both CD4+CD25+ and CD4+CD25− Regulatory Cells Mediate Dominant Transplantation Tolerance

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Engagement of Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Induces Transforming Growth Factor β (TGF-β) Production by Murine CD4+ T Cells

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CD25 Is a Marker for CD4+ Thymocytes That Prevent Autoimmune Diabetes in Rats, But Peripheral T Cells with This Function Are Found in Both CD25+ and CD25− Subpopulations

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Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Regulates the Unfolding of Autoimmune Diabetes

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Suppressor T cells – they’re back and critical for regulation of autoimmunity!

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Cytokine‐related syndrome following injection of anti‐CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation

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T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice.

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Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− Thymocytes

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Tolerance to Islet Autoantigens in Type 1 Diabetes

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Human in vivo antigenic modulation induced by the anti‐T cell OKT3 monoclonal antibody

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The autocrine production of transforming growth factor-beta1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA.

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Transforming Growth Factor β (TGF-β)-dependent Inhibition of T Helper Cell 2 (Th2)-induced Autoimmunity by Self–Major Histocompatibility Complex (MHC) Class II–specific, Regulatory CD4+ T Cell Lines

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PHASE I STUDY OF AN ENGINEERED AGLYCOSYLATED HUMANIZED CD3 ANTIBODY IN RENAL TRANSPLANT REJECTION1

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ANTI-CD3 F(abʼ)2 FRAGMENTS ARE IMMUNOSUPPRESSIVE IN VIVO WITHOUT EVOKING EITHER THE STRONG HUMORAL RESPONSE OR MORBIDITY ASSOCIATED WITH WHOLE mAb

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Interleukin-4 Deficiency Does Not Exacerbate Disease in NOD Mice

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Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells

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Lack of L‐selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel‐14 antibody treatment

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Immunologic "vaccination" for the prevention of autoimmune diabetes (type 1A).

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TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

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Normalization of obesity-associated insulin resistance through immunotherapy

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THE NOD MOUSE: A Model of Immune Dysregulation

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

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