The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis
Open accessAbstract
We developed genetically encoded fluorescence resonance energy transfer (FRET)-based sensors that display a large ratiometric change upon Zn2+ binding, have affinities that span the pico- to nanomolar range and can readily be targeted to subcellular organelles. Using this sensor toolbox we found that cytosolic Zn2+ was buffered at 0.4 nM in pancreatic β cells, and we found substantially higher Zn2+ concentrations in insulin-containing secretory vesicles.
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Metals, Toxicity and Oxidative Stress
Valko, M., Morris, H., & Cronin, M. (2005) · Current Medicinal Chemistry · doi:10.2174/0929867053764635 · Cited by 5,018
A genome-wide association study identifies novel risk loci for type 2 diabetes
Sladek, R., Rocheleau, G., Rung, J., Dina, C., Shen, L., Serre, D., Boutin, P., Vincent, D., Belisle, A., Hadjadj, S., et al. (2007) · Nature · doi:10.1038/nature05616 · Cited by 2,993
Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis
Outten, C. E., & O'Halloran, A. T. V. (2001) · Science · doi:10.1126/science.1060331 · Cited by 1,489
Small-Molecule Fluorescent Sensors for Investigating Zinc Metalloneurochemistry
Nolan, E. M., & Lippard, S. J. (2009) · Accounts of Chemical Research · doi:10.1021/ar8001409 · Cited by 620
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor
Wallace, D. J., zum Alten Borgloh, S. M., Astori, S., Yang, Y., Bausen, M., Kügler, S., Palmer, A. E., Tsien, R. Y., Sprengel, R., Kerr, J. N. D., et al. (2008) · Nature Methods · doi:10.1038/nmeth.1242 · Cited by 191
Cited by
Kambe, T., Tsuji, T., Hashimoto, A., & Itsumura, N. (2015) · Physiological Reviews · doi:10.1152/physrev.00035.2014 · Cited by 1,158
Small-Molecule Two-Photon Probes for Bioimaging Applications
Kim, H. M., & Cho, B. R. (2015) · Chemical Reviews · doi:10.1021/cr5004425 · Cited by 1,047
Zinc biochemistry: From a single zinc enzyme to a key element of life
Maret, W. (2013) · Advances in Nutrition · doi:10.3945/an.112.003038 · Cited by 818
The biological inorganic chemistry of zinc ions
Krężel, A., & Maret, W. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.04.010 · Cited by 768
The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus
Gerber, P. A., & Rutter, G. A. (2017) · Antioxidants & Redox Signaling · doi:10.1089/ars.2016.6755 · Cited by 654
Self-citation
Metadata
- Authors
- Vinkenborg, J. L., Nicolson, T. J., Bellomo, E. A., Koay, M. S., Rutter, G. A., & Merkx, M.
- Venue
- Nature Methods
- Published
- 2009-08-30
- Volume
- 6
- Issue
- 10
- Pages
- 737-740
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2110383903
- Cited by
- 432
- References
- 5
- FWCI
- 16.50
- Type
- journal article
- Language
- en
- Open access
- green
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- Vinkenborg, J. L., Nicolson, T. J., Bellomo, E. A., Koay, M. S., Rutter, G. A., & Merkx, M. (2009). Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis. Nature Methods. https://doi.org/10.1038/nmeth.1368
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