The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis
Open accessAbstract
We developed genetically encoded fluorescence resonance energy transfer (FRET)-based sensors that display a large ratiometric change upon Zn2+ binding, have affinities that span the pico- to nanomolar range and can readily be targeted to subcellular organelles. Using this sensor toolbox we found that cytosolic Zn2+ was buffered at 0.4 nM in pancreatic β cells, and we found substantially higher Zn2+ concentrations in insulin-containing secretory vesicles.
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Cites
Metals, Toxicity and Oxidative Stress
Valko, M., Morris, H., & Cronin, M. (2005) · Current Medicinal Chemistry · doi:10.2174/0929867053764635 · Cited by 5,018
A genome-wide association study identifies novel risk loci for type 2 diabetes
Sladek, R., Rocheleau, G., Rung, J., Dina, C., Shen, L., Serre, D., Boutin, P., Vincent, D., Belisle, A., Hadjadj, S., et al. (2007) · Nature · doi:10.1038/nature05616 · Cited by 2,993
Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis
Outten, C. E., & O'Halloran, A. T. V. (2001) · Science · doi:10.1126/science.1060331 · Cited by 1,489
Small-Molecule Fluorescent Sensors for Investigating Zinc Metalloneurochemistry
Nolan, E. M., & Lippard, S. J. (2009) · Accounts of Chemical Research · doi:10.1021/ar8001409 · Cited by 620
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor
Wallace, D. J., zum Alten Borgloh, S. M., Astori, S., Yang, Y., Bausen, M., Kügler, S., Palmer, A. E., Tsien, R. Y., Sprengel, R., Kerr, J. N. D., et al. (2008) · Nature Methods · doi:10.1038/nmeth.1242 · Cited by 191
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Kim, H. M., & Cho, B. R. (2015) · Chemical Reviews · doi:10.1021/cr5004425 · Cited by 1,047
Zinc biochemistry: From a single zinc enzyme to a key element of life
Maret, W. (2013) · Advances in Nutrition · doi:10.3945/an.112.003038 · Cited by 818
The biological inorganic chemistry of zinc ions
Krężel, A., & Maret, W. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.04.010 · Cited by 768
The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus
Gerber, P. A., & Rutter, G. A. (2017) · Antioxidants & Redox Signaling · doi:10.1089/ars.2016.6755 · Cited by 654
Self-citationThe Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective
Kimura, T., & Kambe, T. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17030336 · Cited by 409
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Self-citationSLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome
Perez, Y., Shorer, Z., Liani-Leibson, K., Chabosseau, P., Kadir, R., Volodarsky, M., Halperin, D., Barber-Zucker, S., Shalev, H., Schreiber, R., et al. (2017) · Brain · doi:10.1093/brain/awx013 · Cited by 99
Self-citationBacillithiol is a major buffer of the labile zinc pool in Bacillus subtilis
Ma, Z., Chandrangsu, P., Helmann, T. C., Romsang, A., Gaballa, A., & Helmann, J. D. (2014) · Molecular Microbiology · doi:10.1111/mmi.12794 · Cited by 96
Metal site occupancy and allosteric switching in bacterial metal sensor proteins
Guerra, A. J., & Giedroc, D. P. (2012) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.11.021 · Cited by 77
Upmanyu, N., Jin, J., Emde, H. V. D., Ganzella, M., Bösche, L., Malviya, V. N., Zhuleku, E., Politi, A. Z., Ninov, M., Silbern, I., et al. (2022) · Neuron · doi:10.1016/j.neuron.2022.02.008 · Cited by 69
Fluorescent Protein-Based Sensors for Detecting Essential Metal Ions across the Tree of Life
Jensen, G. C., Janis, M. K., Nguyen, H. N., David, O. W., & Zastrow, M. L. (2024) · ACS Sensors · doi:10.1021/acssensors.3c02695 · Cited by 25
Genetically encoded fluorescent sensors for metals in biology
Torres-Ocampo, A. P., & Palmer, A. E. (2023) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2023.102284 · Cited by 22
Janiszewski, L. N., Minson, M., Allen, M. A., Dowell, R. D., & Palmer, A. E. (2021) · Infection and Immunity · doi:10.1128/iai.00273-21 · Cited by 6
Metadata
- Authors
- Vinkenborg, J. L., Nicolson, T. J., Bellomo, E. A., Koay, M. S., Rutter, G. A., & Merkx, M.
- Venue
- Nature Methods
- Published
- 2009-08-30
- Volume
- 6
- Issue
- 10
- Pages
- 737-740
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2110383903
- Cited by
- 432
- References
- 5
- FWCI
- 16.50
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
