The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
TGFα shedding assay: an accurate and versatile method for detecting GPCR activation
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Crystal structure of the β2 adrenergic receptor–Gs protein complex
Rasmussen, S. G. F., DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., et al. (2011) · Nature · doi:10.1038/nature10361 · Cited by 3,009
Guide to receptors and channels (GRAC), 5th edition
Alexander, S., Mathie, A., & Peters, J. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01649_1.x · Cited by 1,947
An Essential Role for Ectodomain Shedding in Mammalian Development
Peschon, J. J., Slack, J. L., Reddy, P., Stocking, K. L., Sunnarborg, S. W., Lee, D. C., Russell, W. E., Castner, B. J., Johnson, R. S., Fitzner, J. N., et al. (1998) · Science · doi:10.1126/science.282.5392.1281 · Cited by 1,607
EDWARDS, D., HANDSLEY, M., & PENNINGTON, C. (2008) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2008.08.001 · Cited by 1,161
The G protein-coupled receptor repertoires of human and mouse
Vassilatis, D. K., Hohmann, J. G., Zeng, H., Li, F., Ranchalis, J. E., Mortrud, M. T., Brown, A., Rodriguez, S. S., Weller, J. R., Wright, A. C., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0230374100 · Cited by 790
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
Conklin, B. R., Farfel, Z., Lustig, K. D., Julius, D., & Bourne, H. R. (1993) · Nature · doi:10.1038/363274a0 · Cited by 723
Conformational complexity of G-protein-coupled receptors
Kobilka, B. K., & Deupi, X. (2007) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2007.06.003 · Cited by 694
Noguchi, K., Ishii, S., & Shimizu, T. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302648200 · Cited by 557
Guide to Receptors and Channels (GRAC), 3rd edition
Alexander, S. P. H., Mathie, A., & Peters, J. A. (2008) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707746 · Cited by 510
Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C
Offermanns, S., & Simon, M. I. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.25.15175 · Cited by 498
Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα 13 Deficiency
Offermanns, S., Mancino, V., Revel, J.-P., & Simon, M. I. (1997) · Science · doi:10.1126/science.275.5299.533 · Cited by 338
The G Protein Subunit Gene Families
Downes, G. B., & Gautam, N. (1999) · Genomics · doi:10.1006/geno.1999.5992 · Cited by 330
Chun, J., Hla, T., Lynch, K. R., Spiegel, S., & Moolenaar, W. H. (2010) · Pharmacological Reviews · doi:10.1124/pr.110.003111 · Cited by 330
Inflammatory Skin and Bowel Disease Linked to ADAM17 Deletion
Blaydon, D. C., Biancheri, P., Di, W.-L., Plagnol, V., Cabral, R. M., Brooke, M. A., van Heel, D. A., Ruschendorf, F., Toynbee, M., Walne, A., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1100721 · Cited by 308
Tokumaru, S., Higashiyama, S., Endo, T., Nakagawa, T., Miyagawa, J.-I., Yamamori, K., Hanakawa, Y., Ohmoto, H., Yoshino, K., Shirakata, Y., et al. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.2.209 · Cited by 305
Self-citationShimizu, Y., Thumkeo, D., Keel, J., Ishizaki, T., Oshima, H., Oshima, M., Noda, Y., Matsumura, F., Taketo, M. M., & Narumiya, S. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200411179 · Cited by 304
Bond, R. A., & IJzerman, A. P. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.12.007 · Cited by 250
Lysophospholipid receptor nomenclature
Lynch, K. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(02)00138-5 · Cited by 222
Liu, J., Conklin, B. R., Blin, N., Yun, J., & Wess, J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11642 · Cited by 207
Makide, K., Kitamura, H., Sato, Y., Okutani, M., & Aoki, J. (2009) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2009.04.009 · Cited by 200
Self-citationAnalysis of Allosterism in Functional Assays
Ehlert, F. J. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.090886 · Cited by 168
Identification of a lysophosphatidylserine receptor on mast cells
Sugo, T., Tachimoto, H., Chikatsu, T., Murakami, Y., Kikukawa, Y., Sato, S., Kikuchi, K., Nagi, T., Harada, M., Ogi, K., et al. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.01.069 · Cited by 159
LPA‐producing enzyme PA‐PLA1α regulates hair follicle development by modulating EGFR signalling
Inoue, A., Arima, N., Ishiguro, J., Prestwich, G. D., Arai, H., & Aoki, J. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.296 · Cited by 152
Self-citationROCK‐I and ROCK‐II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo
Thumkeo, D., Shimizu, Y., Sakamoto, S., Yamada, S., & Narumiya, S. (2005) · Genes to Cells · doi:10.1111/j.1365-2443.2005.00882.x · Cited by 151
G Protein Selectivity Is Regulated by Multiple Intracellular Regions of GPCRs
Wong, S. K.-F. (2003) · Neurosignals · doi:10.1159/000068914 · Cited by 148
Serine Phospholipid-specific Phospholipase A That Is Secreted from Activated Platelets
Sato, T., Aoki, J., Nagai, Y., Dohmae, N., Takio, K., Doi, T., Arai, H., & Inoue, K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.4.2192 · Cited by 147
Self-citationAltered immune response in mice deficient for the G protein-coupled receptor GPR34
Liebscher, I., Müller, U., Teupser, D., Engemaier, E., Engel, K. M. Y., Ritscher, L., Thor, D., Sangkuhl, K., Ricken, A., Wurm, A., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.196659 · Cited by 106
Deficiency of TNFα Converting Enzyme (TACE/ADAM17) Causes a Lean, Hypermetabolic Phenotype in Mice
Gelling, R. W., Yan, W., Al‐Noori, S., Pardini, A. W., Morton, G. J., Ogimoto, K., Schwartz, M. W., & Dempsey, P. J. (2008) · Endocrinology · doi:10.1210/en.2008-0775 · Cited by 75
Iwashita, M., Makide, K., Nonomura, T., Misumi, Y., Otani, Y., Ishida, M., Taguchi, R., Tsujimoto, M., Aoki, J., Arai, H., et al. (2009) · Journal of Medicinal Chemistry · doi:10.1021/jm900598m · Cited by 74
Self-citationZhao, Z., & Xu, Y. (2009) · Journal of Chromatography B · doi:10.1016/j.jchromb.2009.08.032 · Cited by 58
Canault, M., Certel, K., Schatzberg, D., Wagner, D. D., & Hynes, R. O. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013433 · Cited by 31
Cited by
Illuminating G-Protein-Coupling Selectivity of GPCRs
Inoue, A., Raimondi, F., Kadji, F. M. N., Singh, G., Kishi, T., Uwamizu, A., Ono, Y., Shinjo, Y., Ishida, S., Arang, N., et al. (2019) · Cell · doi:10.1016/j.cell.2019.04.044 · Cited by 638
Self-citationA genetically encoded fluorescent sensor for rapid and specific in vivo detection of norepinephrine
Feng, J., Zhang, C., Lischinsky, J. E., Jing, M., Zhou, J., Wang, H., Zhang, Y., Dong, A., Wu, Z., Wu, H., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.02.037 · Cited by 545
Emerging roles of lysophospholipids in health and disease
Tan, S. T., Ramesh, T., Toh, X. R., & Nguyen, L. N. (2020) · Progress in Lipid Research · doi:10.1016/j.plipres.2020.101068 · Cited by 371
Enzyme Inhibitor Discovery by Activity-Based Protein Profiling
Niphakis, M. J., & Cravatt, B. F. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035708 · Cited by 366
Lysophospholipid receptor nomenclature review: IUPHAR Review 8
Kihara, Y., Maceyka, M., Spiegel, S., & Chun, J. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12678 · Cited by 324
Metadata
- Authors
- Inoue, A., Ishiguro, J., Kitamura, H., Arima, N., Okutani, M., Shuto, A., Higashiyama, S., Ohwada, T., Arai, H., Makide, K., & Aoki, J.
- Venue
- Nature Methods
- Published
- 2012-09-16
- Volume
- 9
- Issue
- 10
- Pages
- 1021-1029
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2076866060
- Cited by
- 360
- References
- 31
- FWCI
- 5.46
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
