Cas9 as a versatile tool for engineering biology

Mali, Prashant, Esvelt, Kevin M, Church, George M·2013·Nature Methods

Cited by (999)

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  3. Gene editing tool-loaded biomimetic cationic vesicles with highly efficient bacterial internalization for in vivo eradication of pathogens
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  5. Modelling Neuromuscular Diseases in the Age of Precision Medicine
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  6. Enhancement of Gene Editing and Base Editing with Therapeutic Ribonucleoproteins through In Vivo Delivery Based on Absorptive Silica Nanoconstruct
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  7. A simple and highly efficient method for multi‐allelic CRISPR‐Cas9 editing in primary cell cultures
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  8. Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells
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  9. grID: A CRISPR-Cas9 guide RNA Database and Resource for Genome-Editing
    Vinod Jaskula-Ranga, Donald J. Zack · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Gene therapy for Duchenne muscular dystrophy
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  11. Developing CRISPR‐based sex‐ratio distorters for the genetic control of fruit fly pests: A how to manual
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  12. Beyond Seek and Destroy: how to Generate Allelic Series Using Genome Editing Tools
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    Ningmei Zeng, Jiankang Bao, Tingting Shu, Chuang Shi, Gang Zhai, Xia Jin, Jiangyan He, Qiyong Lou, Zhan Yin · 2022 · Frontiers in Endocrinology
  14. The CRISPR Revolution in Genome Engineering: Perspectives from Religious Ethics
    Jung Lee · 2022 · Journal of Religious Ethics
  15. The future of drug discovery: enabling technologies for enhancing lead characterization and profiling therapeutic potential
    David R. Janero · 2014 · Expert Opinion on Drug Discovery
  16. Gene editing: how to stay on-target with CRISPR
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  17. Gene editing of stem cells for kidney disease modelling and therapeutic intervention
    Ricky WK Lau, Bo Wang, Sharon D. Ricardo · 2018 · Nephrology
  18. Functional analysis of the UL24 protein of suid herpesvirus 1
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  19. Bi-FoRe: an efficient bidirectional knockin strategy to generate pairwise conditional alleles with fluorescent indicators
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  20. Efficient Multi‐Allelic Genome Editing of Primary Cell Cultures via CRISPR‐Cas9 Ribonucleoprotein Nucleofection
    Pia Hoellerbauer, Megan Kufeld, Patrick J. Paddison · 2020 · Current Protocols in Stem Cell Biology
  21. Machine learning based CRISPR gRNA design for therapeutic exon skipping
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  23. CRISPR Diversity in E. coli Isolates from Australian Animals, Humans and Environmental Waters
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  24. RNA-Redesign: a web server for fixed-backbone 3D design of RNA: Figure 1.
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  31. The potential application and challenge of powerful CRISPR/Cas9 system in cardiovascular research
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    Patrick Lajoie, Elena N. Fazio, Erik L. Snapp · 2014 · Endoplasmic Reticulum Stress in Diseases
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  48. Recent progress of molecular diagnosis via CRISPR Cas-based biosensors and bioassays
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  49. Advances in and Perspectives on Transgenic Technology and CRISPR-Cas9 Gene Editing in Broccoli
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  57. Genome Editing in Human Pluripotent Stem Cells
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  64. CRISPR/Cas9: The Leading Edge of Genome Editing Technology
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