Cas9 as a versatile tool for engineering biology
Mali, Prashant, Esvelt, Kevin M, Church, George M·2013·Nature Methods
Cited by (999)
Items 301–400 of 999
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- Polycistronic tRNA and CRISPR guide-RNA enables highly efficient multiplexed genome engineering in human cellsFengping Dong, Kabin Xie, Yueying Chen, Yinong Yang, Yingwei Mao · 2016 · Biochemical and Biophysical Research Communications
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- CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs)Xue Yu Hu, Li Li, Xinyi Yu, Ruyi Zhang, Shujuan Yan, Zongyue Zeng, Yi Shu, Chen Zhao, Xingye Wu, Jiayan Lei et al. · 2017 · Oncotarget
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- CRISPR/Cas9-mediated conversion of eGFP- into Gal4-transgenic lines in zebrafishThomas O. Auer, Karine Duroure, Jean‐Paul Concordet, Filippo Del Bene · 2014 · Nature Protocols
- Genetic Mapping of Pathogenesis Determinants in Toxoplasma gondiiMichael S. Behnke, Jitender Prakash Dubey, L. David Sibley · 2016 · Annual Review of Microbiology
- Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approachesEmenike K. Onyido, Eloise Sweeney, Abdolrahman Shams Nateri · 2016 · Molecular Cancer
- Modeling Late-Onset Sporadic Alzheimer’s Disease through BMI1 DeficiencyAnthony Flamier, Jida El Hajjar, James Adjaye, Karl J. L. Fernandes, Mohamed Abdouh, Gilbert Bernier · 2018 · Cell Reports
- The CRISPR/Cas9 genome editing methodology as a weapon against human viruses.Martyn K. White, Wenhui Hu, Kamel Khalili · 2015 · PubMed
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- Targeting CD44 by CRISPR-Cas9 in Multi-Drug Resistant Osteosarcoma CellsXiao Wei Zheng, Jia Wan, Ayub Abdulle Nur, Pencheng Dou, Henry J. Mankin, Tang Liu, Zhengxiao Ouyang · 2018 · Cellular Physiology and Biochemistry
- Application of Genome Editing in Tomato Breeding: Mechanisms, Advances, and ProspectsHymavathi Salava, Sravankumar Thula, Vijee Mohan, Rahul Kumar, Fatemeh Maghuly · 2021 · International Journal of Molecular Sciences
- Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9Ivailo Simoff, Maria Karlgren, Maria Backlund, Anne-Christine Lindström, Fabienne Zdenka Gaugaz, Pär Matsson, Per Artursson · 2016 · Journal of Pharmaceutical Sciences
- A morphospace for synthetic organs and organoids: the possible and the actualAina Ollé-Vila, Salva Duran‐Nebreda, Núria Conde Pueyo, Raúl Montañez, Ricard V. Solé · 2016 · Integrative Biology
- CRISPR/Cas9-based genome editing in the era of CAR T cell immunotherapyJanuary Salas-McKee, Weimin Kong, Whitney Lynn Gladney, Julie K. Jadlowsky, Gabriela Plesa, Megan M. Suhoski, Joseph A. Fraietta · 2019 · Human Vaccines & Immunotherapeutics
- Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease EngineeringXiaoqiang Huang, Dongshan Yang, Jifeng Zhang, Jie Xu, Y. Eugene Chen · 2022 · Cells
- CRISPR-Cas9-Based Knockout of the Prion Protein and Its Effect on the ProteomeMohadeseh Mehrabian, Brethour Dylan, Sarah MacIsaac, Jin Kyu Kim, C. Geeth Gunawardana, Hansen Wang, Gerold Schmitt‐Ulms · 2014 · PLoS ONE
- A versatile reporter system for CRISPR-mediated chromosomal rearrangementsYingxiang Li, Angela I. Park, Haiwei Mou, Cansu Colpan, Aizhan Bizhanova, Elliot H. Akama‐Garren, Nik Joshi, Eric A. Hendrickson, David M. Feldser, Hao Yin et al. · 2015 · Genome biology
- Biosynthesis of therapeutic natural products using synthetic biologyAli Raza Awan, W. M. Shaw, Tom Ellis · 2016 · Advanced Drug Delivery Reviews
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- Application of CRISPR/Cas9 genome editing to the study and treatment of diseaseAndrea Pellagatti, Hamid Dolatshad, Simona Valletta, Jacqueline Boultwood · 2015 · Archives of Toxicology
- Engineered Swine Models of CancerAdrienne L. Watson, Daniel F. Carlson, David A. Largaespada, Perry B. Hackett, Scott C. Fahrenkrug · 2016 · Frontiers in Genetics
- Bok regulates mitochondrial fusion and morphologyJacqualyn J. Schulman, Laura M. Szczesniak, Eric N. Bunker, Heather A. Nelson, Michael Wm. Roe, Larry E. Wagner, David I. Yule, Richard J.H. Wojcikiewicz · 2019 · Cell Death and Differentiation
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- Off‐target assessment of CRISPR ‐ C as9 guiding RNA s in human i PS and mouse ES cellsE‐Pien Tan, Yilong Li, Martin Del Castillo Velasco‐Herrera, Kosuke Yusa, Allan Bradley · 2014 · genesis
- PhytoCRISP-Ex: a web-based and stand-alone application to find specific target sequences for CRISPR/CAS editingAchal Rastogi, Omer Murik, Chris Bowler, Leı̈la Tirichine · 2016 · BMC Bioinformatics
- Recent advances in genome editing and creation of genetically modified pigsJames R. Butler, Joseph M. Ladowski, Gregory R. Martens, Matthew F. Tector, Alfred Joseph Tector · 2015 · International Journal of Surgery
- CRISPR-Cas9, the new kid on the block of fungal molecular biologySven Krappmann · 2016 · Medical Mycology
- Retinoic Acid and BMP4 Cooperate with TP63 to alter Chromatin Dynamics during Surface Epithelial CommitmentJillian M. Pattison, Sandra P. Melo, Samantha N. Piekos, J. Torkelson, E. Bashkirova, Maxwell R. Mumbach, Charlotte Rajasingh, H. Zhen, Ling-Jie Li, Eric J. Liaw et al. · 2018 · Nature Genetics
- Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9Gigi C.G. Choi, Peng Zhou, Chaya T. L. Yuen, Becky K.C. Chan, Feng Xu, Siyu Bao, Hoi Yee Chu, Dawn Thean, Kaeling Tan, Koon Ho Wong et al. · 2019 · Nature Methods
- Engineering biological systems toward a sustainable bioeconomyMateus Schreiner Garcez Lopes · 2015 · Journal of Industrial Microbiology & Biotechnology
- Multiplexed Knockouts in the Model Diatom Phaeodactylum by Episomal Delivery of a Selectable Cas9Mark Moosburner, Pardis Gholami, James K. McCarthy, Maxine H. Tan, Vincent A. Bielinski, Andrew Ellis Allen · 2020 · Frontiers in Microbiology
- Target-dependent nickase activities of the CRISPR–Cas nucleases Cpf1 and Cas9Becky Xu Hua Fu, Justin Smith, Ryan T. Fuchs, Megumu Yamada Mabuchi, Jennifer L. Curcuru, G. Brett Robb, Andrew Z. Fire · 2019 · Nature Microbiology
- 3D genome organization in health and disease: emerging opportunities in cancer translational medicineDeepak Babu, Melissa J. Fullwood · 2015 · Nucleus
- Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas systemRichard D. Sokolowski, Shirley Graham, Malcolm F. White · 2014 · Nucleic Acids Research
- CRISPR/Cas9 and cancer targets: future possibilities and present challengesMartyn K. White, Kamel Khalili · 2016 · Oncotarget
- Use of CRISPR/Cas9-engineered INS-1 pancreatic β cells to define the pharmacology of dual GIPR/GLP-1R agonistsJacqueline Naylor, Arthur T. Suckow, Asha Seth, David J. Baker, Isabelle Sermadiras, Peter Ravn, Rob Howes, Jian‐Liang Li, Mike R. Snaith, Matthew P. Coghlan et al. · 2016 · Biochemical Journal
- Unexpected evolutionary benefit to phages imparted by bacterial CRISPR-Cas9Tao Pan, Xiaorong Wu, Venigalla Basaveswara Rao · 2018 · Science Advances
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- The pentatricopeptide repeat protein MTSF2 stabilizes a nad1 precursor transcript and defines the 3΄ end of its 5΄-half intronChuande Wang, Fabien Aubé, Noelya Planchard, Martine Quadrado, Céline Dargel-Graffin, Fabien Nogué, Hakim Mireau · 2017 · Nucleic Acids Research
- HIV Excision Utilizing CRISPR/Cas9 Technology: Attacking the Proviral Quasispecies in Reservoirs to Achieve a CureBrian Wigdahl · 2014 · MOJ Immunology
- Tools and applications in synthetic biologyI. Cody MacDonald, Tara L. Deans · 2016 · Advanced Drug Delivery Reviews
- The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic ApproachesB. Motta, P. Pramstaller, A. Hicks, A. Rossini · 2017 · Stem Cells International
- Amplification-free, CRISPR-Cas9 Targeted Enrichment and SMRT Sequencing of Repeat-Expansion Disease Causative Genomic RegionsYu‐Chih Tsai, David Greenberg, James Powell, Ida Höijer, Adam Ameur, Maya Strahl, Ethan Ellis, Inger Jonasson, Ricardo Mouro Pinto, Vanessa C. Wheeler et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Alternative polyadenylation in the nervous system: To what lengths will 3′ UTR extensions take us?Pedro Miura, Piero Sanfilippo, Sol Shenker, Eric C. Lai · 2014 · BioEssays
- CRISPR/Cas9-mediated gene modification and gene knock out in the human-infective parasite Trichomonas vaginalisBrian D. Janssen, Yi-Pei Chen, Brenda M. Molgora, Shuqi Wang, Augusto Simões-Barbosa, Patricia J. Johnson · 2018 · Scientific Reports
- A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectableLaure Leynaud-Kieffer, Samuel C. Curran, Irene Kim, Jon Karl Magnuson, John M. Gladden, Scott Baker, Blake Alexander Simmons · 2019 · PLoS ONE
- CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative DiseasesWeili Yang, Zhuchi Tu, Qiang Sun, Xiao‐Jiang Li · 2016 · Frontiers in Molecular Neuroscience
- Emerging frontiers in drug delivery with special focus on novel techniques for targeted therapiesLing Yu, Shengmao Liu, Shengnan Jia, Feng Xu · 2023 · Biomedicine & Pharmacotherapy
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- Application and optimization of CRISPR–Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum)Ji‐Feng Fei, Wilson Pak-Kin Lou, Dunja Knapp, Prayag Murawala, Tobias Gerber, Yuka Taniguchi, Sergej Nowoshilow, Shahryar Khattak, Elly Margaret Tanaka · 2018 · Nature Protocols
- Current state of research on non‐human primate models of Alzheimer’s diseaseHong‐Wei Li, Ling Zhang, Chuan Qin · 2019 · Animal Models and Experimental Medicine
- Justice in CRISPR/Cas9 Research and Clinical ApplicationsClara Cornelia Hildebrandt, Jonathan Michael Marron · 2018 · The AMA Journal of Ethic
- Gold Nanoparticle-Mediated Gene TherapyGayathri A. Kanu, Javad B. M. Parambath, Raed O. Abu Odeh, Ahmed A. M. Mohamed · 2022 · Cancers
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- Development of CRISPR/Cas9 mediated virus resistance in agriculturally important cropsSurender Khatodia, Kirti Bhatotia, Narendra Tuteja · 2017 · Bioengineered
- Precision gene editing technology and applications in nephrologyZachary WareJoncas, Jarryd M. Campbell, Gabriel Martínez‐Gálvez, William A.C. Gendron, Michael A. Barry, Peter C. Harris, Caroline R. Sussman, Stephen Carl Ekker · 2018 · Nature Reviews Nephrology
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- CRISPR/Cas9-Based Genome Editing in PlantsYaling Zhang, Xingliang Ma, Xianrong Xie, Yao‐Guang Liu · 2017 · Progress in molecular biology and translational science
- CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized miceQiaoqiao Xiao, Shuliang Chen, Qiankun Wang, Zhepeng Liu, Shuai Liu, Huan Deng, Wei Hou, Dongcheng Wu, Yong Xiong, Jiafu Li et al. · 2019 · Retrovirology
- Approach for in vivo delivery of CRISPR/Cas system: a recent update and future prospectYu-Fan Chuang, Andrew J. Phipps, Fan‐Li Lin, Valerie F G Hecht, Alex William Hewitt, Peng‐Yuan Wang, Guei‐Sheung Liu · 2021 · Cellular and Molecular Life Sciences
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- In vivo PCSK9 gene editing using an all-in-one self-cleavage AAV-CRISPR systemQian Li, Jing Su, Yi Liu, Xiu Jin, Xiaomei Zhong, Li Mo, Qingnan Wang, Hongxin Deng, Yang Yang · 2021 · Molecular Therapy — Methods & Clinical Development
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- Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systemsHan Wu, Qishuai Liu, Hui Shi, Jingke Xie, Quanjun Zhang, Zhen Ouyang, Nan Li, Yi Yang, Zhaoming Liu, Yu Zhao et al. · 2018 · Cellular and Molecular Life Sciences
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