The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Twin-spot MARCM to reveal the developmental origin and identity of neurons
Open accessAbstract
A comprehensive understanding of the brain requires the analysis of individual neurons. We used twin-spot mosaic analysis with repressible cell markers (twin-spot MARCM) to trace cell lineages at high resolution by independently labeling paired sister clones. We determined patterns of neurogenesis and the influences of lineage on neuron-type specification. Notably, neural progenitors were able to yield intermediate precursors that create one, two or more neurons. Furthermore, neurons acquired stereotyped projections according to their temporal position in various brain sublineages. Twin-spot MARCM also permitted birth dating of mutant clones, enabling us to detect a single temporal fate that required chinmo in a sublineage of six Drosophila central complex neurons. In sum, twin-spot MARCM can reveal the developmental origins of neurons and the mechanisms that underlie cell fate.
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Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs
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Venken, K. J. T., Simpson, J. H., & Bellen, H. J. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.021 · Cited by 450
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Organization and Functional Roles of the Central Complex in the Insect Brain
Pfeiffer, K., & Homberg, U. (2014) · Annual Review of Entomology · doi:10.1146/annurev-ento-011613-162031 · Cited by 392
Sexual Dimorphism in the Fly Brain
Cachero, S., Ostrovsky, A. D., Yu, J. Y., Dickson, B. J., & Jefferis, G. S. X. E. (2010) · Current Biology · doi:10.1016/j.cub.2010.07.045 · Cited by 325
Metadata
- Authors
- Yu, H.-H., Chen, C.-H., Shi, L., Huang, Y., & Lee, T.
- Venue
- Nature Neuroscience
- Published
- 2009-06-14
- Volume
- 12
- Issue
- 7
- Pages
- 947-953
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2091269769
- Cited by
- 158
- References
- 4
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- green
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