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Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
Abstract
The diseased brain hosts a heterogeneous population of myeloid cells, including parenchymal microglia, perivascular cells, meningeal macrophages and blood-borne monocytes. To date, the different types of brain myeloid cells have been discriminated solely on the basis of their localization, morphology and surface epitope expression. However, recent data suggest that resident microglia may be functionally distinct from bone marrow- or blood-derived phagocytes, which invade the CNS under pathological conditions. During the last few years, research on brain myeloid cells has been markedly changed by the advent of new tools in imaging, genetics and immunology. These methodologies have yielded unexpected results, which challenge the traditional view of brain macrophages. On the basis of these new studies, we differentiate brain myeloid subtypes with regard to their origin, function and fate in the brain and illustrate the divergent features of these cells during neurodegeneration.
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“Many of these cytokines are known to be highly elevated in neurological diseases and/or involved in the recruitment of peripheral immune cells into the CNS under pathological conditions”
From iPSC-derived human microglia-like cells to study neurological diseases (2017) · cites this paper as Prinz et al., 2011
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The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics
Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864
Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., et al. (1997) · Science · doi:10.1126/science.276.5321.2045 · Cited by 8,240
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175
Querfurth, H. W., & LaFerla, F. M. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0909142 · Cited by 4,569
ATP mediates rapid microglial response to local brain injury in vivo
Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913
Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
Hanisch, U.-K., & Kettenmann, H. (2007) · Nature Neuroscience · doi:10.1038/nn1997 · Cited by 3,676
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504
Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326
Development of Monocytes, Macrophages, and Dendritic Cells
Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science · doi:10.1126/science.1178331 · Cited by 3,049
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Items 401–500 of 670
Analyses of Microglia Effector Function Using CX3CR1-GFP Knock-In Mice
Garcia, J. A., Cardona, S. M., & Cardona, A. E. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-520-0_27 · Cited by 27
The Microglial Response to Neurodegenerative Disease
Song, W. M., & Colonna, M. (2018) · Advances in immunology · doi:10.1016/bs.ai.2018.04.002 · Cited by 30
Microglial expression of GAT‐1 in the cerebral cortex
Fattorini, G., Catalano, M., Melone, M., Serpe, C., Bassi, S., Limatola, C., & Conti, F. (2019) · Glia · doi:10.1002/glia.23745 · Cited by 29
Myeloid cells in vascular dementia and Alzheimer's disease: Possible therapeutic targets?
García‐Culebras, A., Cuartero, M. I., Peña‐Martínez, C., Moraga, A., Vázquez‐Reyes, S., Castro-Millán, F. J., Cortés‐Canteli, M., Lizasoaín, I., & Moro, M. Á. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16159 · Cited by 27
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Benedictis, C. A. D., Vilella, A., & Grabrucker, A. M. (2019) · Codon Publications eBooks · doi:10.15586/alzheimersdisease.2019.ch6 · Cited by 31
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von Ehr, A., Attaai, A., Neidert, N. N., Potru, P. S., Ruß, T., Zöller, T., & Spittau, B. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00066 · Cited by 29
Liu, X. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s379093 · Cited by 28
Nafea, M., Elharoun, M., Abd-Alhaseeb, M. M., & Helmy, M. W. (2022) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-022-02322-3 · Cited by 27
Breaking and building the wall: the biology of the blood-brain barrier in health and disease
Keller, A. (2013) · Swiss Medical Weekly · doi:10.4414/smw.2013.13892 · Cited by 31
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Zare-Shahabadi, A., Renaudineau, Y., & Rezaei, N. (2013) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2013.838219 · Cited by 29
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Madsen, H. B., & Vilhardt, F. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18010227 · Cited by 26
The Blood–Brain Barrier: Much More Than a Selective Access to the Brain
Sánchez-Cano, F., Hernández‐Kelly, L. C., & Ortega, A. (2021) · Neurotoxicity Research · doi:10.1007/s12640-021-00431-0 · Cited by 30
Kwon, J., Suessmilch, M., McColl, A., Cavanagh, J., & MORRIS, B. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-03216-9 · Cited by 26
Dendritic cells as therapeutic targets in neuroinflammation
Lüssi, F., Zipp, F., & Witsch, E. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2170-9 · Cited by 26
Bao, M., Bade, R., Liu, H., Tsambaa, B., Shao, G., Borjigidai, A., & Cheng, Y. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175992 · Cited by 27
Das, A., Arifuzzaman, S., Kim, S. H., Lee, Y. S., Jung, K. H., & Chai, Y. G. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.03.034 · Cited by 25
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Esteras, N., Alquézar, C., Bermejo-Pareja, F., Bialopiotrowicz, E., Wojda, U., & Martín-Requero, Á. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.10.014 · Cited by 25
Muth, C., Schröck, K., Madore, C., Hartmann, K., Fanek, Z., Butovsky, O., Glatzel, M., & Krasemann, S. (2017) · Brain Pathology · doi:10.1111/bpa.12441 · Cited by 23
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Prado, C. E., Herrada, A. A., Hevia, D., Galleguillos, L., & Escobedo, N. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1540263 · Cited by 26
Magagnoli, J., Ambati, M., Cummings, T. H., Nguyen, J. D. K., Thomas, C. C., Ambati, V. L., Sutton, S. S., Gelfand, B. D., & Ambati, J. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70180 · Cited by 22
Taneo, J., Adachi, T., Yoshida, A., Takayasu, K., Takahara, K., & Inaba, K. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.02.006 · Cited by 25
Liu, W., Sun, F.-X., Wan, M., Jiang, F., Xiangyu, B. O., Lin, L., Tang, H., & Xu, S. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00969 · Cited by 24
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Kloc, M., Uosef, A., Kubiak, J. Z., & Ghobrial, R. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249669 · Cited by 26
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Yu, T., Kuang, H., Wu, X., Huang, Y., Wang, J., & Wen, Z. (2023) · Science Advances · doi:10.1126/sciadv.adf9790 · Cited by 21
Beltagy, D. M., Nawar, N. F., Mohamed, T. M., Tousson, E., & El-Keey, M. M. (2023) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2023.106791 · Cited by 24
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Johnson, T. S., Xiang, S., Helm, B. R., Abrams, Z. B., Neidecker, P., Machiraju, R., Zhang, Y., Huang, K., & Zhang, J. (2020) · Scientific Reports · doi:10.1038/s41598-020-74917-w · Cited by 23
Tang, T. Z., Zhao, Y., Agarwal, D., Tharzeen, A., Patrikeev, I., Zhang, Y., DeJesus, J. E., Bossmann, S. H., Natarajan, B., Motamedi, M., et al. (2024) · iScience · doi:10.1016/j.isci.2024.108932 · Cited by 20
Greene, I. D., Mastaglia, F. L., Meloni, B. P., Ham, K. A., Chieng, J., Mitchell, C. J., Gai, W., & Boulos, S. (2013) · Journal of Neuroscience Research · doi:10.1002/jnr.23331 · Cited by 20
French, S. W., Mendoza, A. S., & Peng, Y. (2016) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2016.03.010 · Cited by 20
Derk, J., Bermudez‐Hernandez, K., Rodriguez, M., He, M., Koh, H., Abedini, A., Li, H., Fenyö, D., & Schmidt, A. M. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180088 · Cited by 21
Sabogal-Guáqueta, A. M., Mitchell-Garcia, T., Hunneman, J., Voshart, D. C., Thiruvalluvan, A., Foijer, F., Kruyt, F. A. E., Trombetta-Lima, M., Eggen, B. J. L., Boddeke, E., et al. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106742 · Cited by 19
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Kuroda, E., Takata, K., Nishimura, K., Oka, H., Sueyoshi, M., Aitani, M., Kouda, A., Satake, S., Shima, C., Toda, Y., et al. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190974 · Cited by 19
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Xu, X., Gao, Y., Wen, L., Zhai, Z., Zhang, S., Shan, F., & Feng, J. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.08.037 · Cited by 18
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Shen, J., Bian, N., Zhao, L., & Wei, J. (2024) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2024.110904 · Cited by 20
Mustroph, M. L., King, M. A., Klein, R. L., & Ramirez, J. J. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.04.034 · Cited by 23
Arcuri, C., Mecca, C., Giambanco, I., & Donato, R. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.04.005 · Cited by 19
Dong, X., Hao, X., Xu, P., Fan, M., Wang, X., Huang, X., Jiang, P., Zeng, L., & Xie, Y. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106825 · Cited by 17
Campos, R. M. P., Barbosa‐Silva, M. C., & Ribeiro‐Resende, V. T. (2021) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2021.05.002 · Cited by 18
Yang, Y. J., Jorstad, N. L., Shiao, C., Cherne, M. K., Khademi, S. B., Montine, K. S., Montine, T. J., & Keene, C. D. (2013) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2013.03.010 · Cited by 18
Verheijden, S., Beckers, L., Munter, S. D., Veldhoven, P. P. V., & Baes, M. I. (2013) · Biochimie · doi:10.1016/j.biochi.2013.08.009 · Cited by 18
Gao, M., Wang, X., Su, S., Feng, W., Lai, Y., Huang, K., Cao, D., & Wang, Q. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01595 · Cited by 18
Tolédano, A., Rodríguez‐Casado, A., Álvarez, M., & Toledano‐Díaz, A. (2024) · Brain Sciences · doi:10.3390/brainsci14111101 · Cited by 19
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Richard, S. A. (2022) · Journal of Oncology · doi:10.1155/2022/8903482 · Cited by 15
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Ramos, P. K. S., Brito, M. D. V., Sílveira, F. T., Salgado, C. G., de Souza, W., Diniz, C. W. P., & Júnior, J. A. P. D. (2014) · Parasitology · doi:10.1017/s0031182014000274 · Cited by 15
Menasria, R., Canivet, C., Piret, J., Gosselin, J., & Boivin, G. (2016) · Journal of General Virology · doi:10.1099/jgv.0.000667 · Cited by 16
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Nie, W., Yue, Y., & Hu, J. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1590909 · Cited by 15
Taipa, R. J. F., Sousa, A. L., Pires, M. M., & Sousa, N. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-160121 · Cited by 15
González-Peña, D., Nixon, S. E., Southey, B. R., Lawson, M. A., McCusker, R. H., Hernández, Á. G., Dantzer, R., Kelley, K. W., & Rodriguez‐Zas, S. L. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157727 · Cited by 14
Batchu, S. (2020) · Neurodegenerative Diseases · doi:10.1159/000510218 · Cited by 14
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Strauss, A., Swann, P., Kigar, S. L., Christou, R., Yarkoni, N. S., Turner, L., Murley, A. G., Chouliaras, L., Shapiro, N. L., Ashton, N. J., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02809-w · Cited by 16
Arroyo, D. S., Gaviglio, E. A., Ramos, J. M. P., Bussi, C., Avalos, M. P., Cancela, L. M., & Iribarren, P. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00770 · Cited by 13
Zondler, L., Herich, S., Kotte, P., Körner, K., Schneider‐Hohendorf, T., Wiendl, H., Schwab, N., & Zarbock, A. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.599936 · Cited by 13
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Luca, C. M. G. D., Consonni, A., Cazzaniga, F. A., Bistaffa, E., Bufano, G., Quitarrini, G., Celauro, L., Legname, G., Eleopra, R., Baggi, F., et al. (2021) · Cells · doi:10.3390/cells11010087 · Cited by 12
Fawaz, C. N., Makki, I., Kazan, J. M., Gebara, N. Y., Andary, F. S., Itani, M. M., El-Sayyed, M., Zeidan, A., Quartarone, A., Darwish, H., et al. (2015) · Expert Review of Proteomics · doi:10.1586/14789450.2015.1099435 · Cited by 13
Melamed, S., Avraham, R., Rothbard, D. E., Noam Erez, A., Israely, T., Klausner, Z., Futerman, A. H., Paran, N., & Vitner, E. B. (2020) · Acta Neuropathologica Communications · doi:10.1186/s40478-020-01020-6 · Cited by 13
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Dai, B., ZHENG, L., Cheung, J. C., Yufeng, L. O. N. G., Liu, J., Wen, C., Qin, L., & Cheng, D. O. N. G. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124063 · Cited by 15
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Dukhinova, M., Kopeikina, E., & Ponomarev, E. D. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7680-5_10 · Cited by 12
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Sarkar, S., Malovic, E., Plante, B., Zenitsky, G. D., Jin, H., Anantharam, V., Kanthasamy, A., & Kanthasamy, A. G. (2017) · Journal of Visualized Experiments · doi:10.3791/55364-v · Cited by 12
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Chen, J., Sun, L., Lyu, H., Zheng, Z. V., Lai, H., Wang, Y., Luo, Y., Lü, G., Chan, W., Guan, S., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.783 · Cited by 12
Kinetics of neurodegeneration based on a risk-related biomarker in animal model of glaucoma
Hayashi, T., Shimazawa, M., Watabe, H., Ose, T., Inokuchi, Y., Ito, Y., Yamanaka, H., Urayama, S.-I., Watanabe, Y., Hara, H., et al. (2013) · Molecular Neurodegeneration · doi:10.1186/1750-1326-8-4 · Cited by 12
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Wang, Z., Liu, Y., Chang, X., & Liu, X. (2025) · Communications Biology · doi:10.1038/s42003-025-07625-8 · Cited by 11
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Metadata
- Authors
- Prinz, M., Priller, J., Sisodia, S. S., & Ransohoff, R. M.
- Affiliations
- University Medical Center Freiburg (DE)
- Charité – Universitätsmedizin Berlin (DE)
- University of Chicago (US)
- Cleveland Clinic (US)
- Corresponding author
- Prinz, Marco
- Ransohoff, Richard M
- Venue
- Nature Neuroscience
- Published
- 2011-09-27
- Volume
- 14
- Issue
- 10
- Pages
- 1227-1235
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2071753918
- Cited by
- 674
- References
- 102
- Citations by year
- 2026: 17 · 2025: 23 · 2024: 33 · 2023: 29 · 2022: 37 · 2021: 42 · 2020: 54 · 2019: 39 · 2018: 50 · 2017: 52 · 2016: 64 · 2015: 60 · 2014: 59 · 2013: 65 · 2012: 46
- FWCI
- 4.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- microglia, meningeal macrophages, perivascular macrophages, neurodegeneration, myeloid cell heterogeneity, phagocytes, brain macrophages
- MeSH terms
- Animals, Brain Diseases, Cell Differentiation, Central Nervous System, Humans, Models, Biological, Nerve Degeneration, Signal Transduction, Microglia, Myeloid Cells
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