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Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington’s Disease and Influences Striatal Synaptic Density

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The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB1 Receptor-Mediated Neuronal Differentiation at Biologically Relevant Concentrations

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Directly Reprogrammed Huntington's Disease Neural Precursor Cells Generate Striatal Neurons Exhibiting Aggregates and Impaired Neuronal Maturation

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PTBP1 promotes hepatocellular carcinoma progression by regulating the skipping of exon 9 in NUMB pre-mRNA

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UPF3B Gene and Nonsense-Mediated mRNA Decay in Autism Spectrum Disorders

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Spatiotemporal Regulation of Transcript Isoform Expression in the Hippocampus

Park, J., & Farris, S. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.694234 · Cited by 5

Genetic effects on brain traits impact cell-type specific gene regulation during neurogenesisPreprint

Aygün, N., Elwell, A. L., Liang, D., Lafferty, M., Cheek, K. E., Courtney, K. P., Mory, J. T., Hadden-Ford, E., Krupa, O., de la Torre-Ubieta, L., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.21.349019 · Cited by 1

Therapeutic potential of astrocyte transdifferentiated neurons

Liang, X., Qin, R., Qin, Q., Xu, W., Xu, H., Lai, X., Shao, L., Li, C., Xie, M., Xiong, X., et al. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-00554 · Cited by 8

Intron retention in PI‐PLC γ1 mRNA as a key mechanism affecting MMP expression in human primary fibroblast‐like synovial cells

Mariano, A., Ammendola, S., Migliorini, A., Leopizzi, M., Raimondo, D., & d’Abusco, A. S. (2024) · Cell Biochemistry and Function · doi:10.1002/cbf.4091 · Cited by 4

RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar foliation

Shen, C.-L., Tsai, Y.-Y. W., Chou, S., Chang, Y., & Tarn, W. (2024) · Communications Biology · doi:10.1038/s42003-024-07328-6 · Cited by 4

Long Noncoding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System

Dong, X., Muppani, N. R., & Wu, J. (2015) · Translational bioinformatics · doi:10.1007/978-94-017-7450-5_3 · Cited by 4

PTBP1 : A candidate gene for intellectual disability

Alkhateeb, A. M., Habbab, W., Aburahma, S. K., & Thompson, I. R. (2017) · Meta Gene · doi:10.1016/j.mgene.2017.05.002 · Cited by 3

The effects and mechanisms of Shibing Xingnao formula in enhancing hippocampal synaptic plasticity in rats with vascular dementia

Gao, X., Zhang, J., Li, J., Ye, H., Meng, D., Tian, F., Wang, N., Xu, Y., & Li, J. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120377 · Cited by 3

The therapeutic potential and mechanisms of targeting the PTBP1/Nogo-A/NgR axis in PTSD induced by single prolonged stress in mice

Liu, B.-Y., Chen, X.-D., Liu, H.-L., Wang, S.-W., Song, Q. Y., Cheng, H., Li, S., Wang, H.-Y., Lu, X.-M., & Yong-tang, W. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-025-01629-4 · Cited by 3

Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks

Lin, L., Kubota, N., Lam, Y.-L., Song, M. M., Zhang, M., & Zheng, S. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117027 · Cited by 6

Unstructured linker regions play a role in the differential splicing activities of paralogous RNA binding proteins PTBP1 and PTBP2

Truong, A., Barton, M., Tran, U. C., Mellody, M. M., Berger, D., Madory, D., Hitch, E., Jibrael, B., Nikolaidis, N., Luchko, T., et al. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.105733 · Cited by 5

‘Cryptic’ exons reveal some of their secrets

Calarco, J. A. (2013) · eLife · doi:10.7554/elife.00476 · Cited by 4

Identification and characterization of two novel alternatively spliced E2F1 transcripts in the rat CNS

Jackson, D., Ting, J. H., Pozniak, P. D., Meurice, C., Schleidt, S. S., Dao, A., Lee, A. H., Klinman, E., & Jordan‐Sciutto, K. L. (2018) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2018.06.003 · Cited by 3

Regulation of Eukaryotic Gene Expression Through Functional Coupling Between Alternative Splicing and Nonsense-mediated Decay

Yap, K., Ramakumar, S., Hamid, F., & Makeyev, E. V. (2026) · Journal of Molecular Biology · doi:10.1016/j.jmb.2026.169764 · Cited by 2

KIS counteracts PTBP2 and regulates alternative exon usage in neurons

Moreno-Aguilera, M., Mendoza, M. B., Neher, A. M., Dodel, M., Mardakheh, F. K., Ortiz, R., & Gallego, C. (2024) · eLife · doi:10.7554/elife.96048 · Cited by 1

MBL-1/Muscleblind regulates neuronal differentiation and controls the splicing of a terminal selector in Caenorhabditis elegans

Lee, H. M. T., Lim, H. Y., He, H., Lau, C. Y., & Zheng, C. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011276 · Cited by 2

SFRS8 Regulates Memory by Modulating RNA Splicing of Synaptic Genes

Zeng, D., Liu, Q., & Zhang, J. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05036-8 · Cited by 2

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1

Zheng, S., Gray, E. E., Chawla, G., Porse, B. T., O’Dell, T. J., & Black, D. L. (2012)

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Boutz, P. L., Stoilov, P., Li, Q., Lin, C.-H., Chawla, G., Ostrow, K., Shiue, L., Ares, M., & Black, D. L. (2007) · Genes & Development · doi:10.1101/gad.1558107 · Cited by 577

Data from: The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

Li, Q., Zheng, S., Han, A., Lin, C.-H., Stoilov, P., Fu, X.-D., & Black, D. L. (2013) · Data Archiving and Networked Services (DANS) · doi:10.5061/dryad.cv39v · Cited by 1

Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention

Yap, K., Lim, Z. Q., Khandelia, P., Friedman, B., & Makeyev, E. V. (2012) · Genes & Development · doi:10.1101/gad.188037.112 · Cited by 286

Alternative splicing and nonsense‐mediated mRNA decay enforce neural specific gene expression

Zheng, S. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.03.003 · Cited by 61