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Hypothalamic sensing of fatty acids
Abstract
Selective regions of the brain, including the hypothalamus, are capable of gathering information on the body's nutritional status in order to implement appropriate behavioral and metabolic responses to changes in fuel availability. This review focuses on direct metabolic signaling within the hypothalamus. There is growing evidence supporting the idea that fatty acid metabolism within discrete hypothalamic regions can function as a sensor for nutrient availability that can integrate multiple nutritional and hormonal signals.
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“Free fatty acid sensing by the hypothalamus is a well-established modulator of neuronal activity57, affecting peripheral metabolism58–60”
From IDOL regulates systemic energy balance through control of neuronal VLDLR expression (2019) · cites this paper as [59]
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“However, basal levels of FAO enzymes and FA transport proteins (such as FATP-1, FATP-4, and FAT/CD36) are expressed in hypothalamic neurons ([93](#B93), [95](#B95)).”
From Mitochondrial fatty acid oxidation in obesity (2013) · cites this paper as [93]
Citations
Cites
Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
Role of leptin in the neuroendocrine response to fasting
Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996) · Nature · doi:10.1038/382250a0 · Cited by 3,117
Environmental Contributions to the Obesity Epidemic
Hill, J. O., & Peters, J. C. (1998) · Science · doi:10.1126/science.280.5368.1371 · Cited by 2,258
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
Brüning, J. C., Gautam, D., Burks, D. J., Gillette, J., Schubert, M., Orban, P. C., Klein, R., Krone, W., Müller-Wieland, D., & Kahn, C. R. (2000) · Science · doi:10.1126/science.289.5487.2122 · Cited by 2,235
Frederich, R. C., Hamann, A., Anderson, S., Löllmann, B., Lowell, B. B., & Flier, J. S. (1995) · Nature Medicine · doi:10.1038/nm1295-1311 · Cited by 1,660
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
Minokoshi, Y., Alquier, T., Furukawa, N., Kim, Y.-B., Lee, A., Xue, B., Mu, J., Foufelle, F., Ferré, P., Birnbaum, M. J., et al. (2004) · Nature · doi:10.1038/nature02440 · Cited by 1,637
Cholecystokinin decreases food intake in rats.
Gibbs, J., Young, R. C., & Smith, G. P. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0034870 · Cited by 1,502
Identification of targets of leptin action in rat hypothalamus.
Schwartz, M. W., Seeley, R. J., Campfield, L. A., Burn, P., & Baskin, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118891 · Cited by 1,499
The role of depot fat in the hypothalamic control of food intake in the rat
Gc, K. (1953) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1953.0009 · Cited by 1,432
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- Thupari, J.N., Landree, L.E., Ronnett, G.V. & Kuhajda, F.P. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc. Natl. Acad. Sci. USA 99, 9498–9502 (2002). · DOI
Cited by
Sorted by citations
Items 301–400 of 479
Oh, Y. T., Oh, K.-S., Kang, I., & Youn, J. H. (2012) · Endocrinology · doi:10.1210/en.2012-1330 · Cited by 16
Dietary triglycerides as signaling molecules that influence reward and motivation
Berland, C., Cansell, C., Hnasko, T. S., Magnan, C., & Luquet, S. H. (2016) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2016.03.005 · Cited by 16
Long Chain Fatty Acids Differentially Regulate Sub-populations of Arcuate POMC and NPY Neurons
Michael, N. J., & Watt, M. J. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.09.045 · Cited by 16
Metabolic Therapy in Heart Failure
Lopatin, Y. (2015) · Cardiac failure review · doi:10.15420/cfr.2015.1.2.112 · Cited by 16
Warne, J. P., Horneman, H. F., Ginsberg, A. B., Pecoraro, N. C., Foster, M. T., Akana, S. F., & Dallman, M. F. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2007.01593.x · Cited by 16
Marsollier, N., Kassis, N., Mezghenna, K., Soty, M., Fioramonti, X., Lacombe, A., Joly‐Amado, A., Pillot, B., Zitoun, C., Vilar, J., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006649 · Cited by 16
Lord, M. N., Heo, J., Schifino, A. G., Hoffman, J. R., Donohue, K. N., Call, J. A., & Noble, E. E. (2021) · Nutrients · doi:10.3390/nu13124222 · Cited by 16
Dearden, L., Furigo, I. C., Pantaleão, L. C., Wong, L. W. P., Fernandez‐Twinn, D. S., de Almeida-Faria, J., Kentistou, K. A., Carreira, M. V., Bidault, G., Vidal‐Puig, A., et al. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3002641 · Cited by 18
van Galen, K. A., Booij, J., Schrantee, A., Adriaanse, S. M., Unmehopa, U. A., Fliers, E., Schwartz, G. J., Dileone, R., ter Horst, K. W., la Fleur, S. E., et al. (2021) · Metabolism · doi:10.1016/j.metabol.2021.154839 · Cited by 16
Self-citationCentral Control of Glucose Homeostasis
Puglianiello, A., & Cianfarani, S. (2006) · The Review of Diabetic Studies · doi:10.1900/rds.2006.3.54 · Cited by 14
Metabolomic profiles of 38 acylcarnitines in major depressive episodes before and after treatment
Tayeb, A. E. K. A., Colle, R., Chappell, K., El‐Asmar, K., Acquaviva, C., David, D. J. P., Trabado, S., Chanson, P., Fève, B., Becquemont, L., et al. (2023) · Psychological Medicine · doi:10.1017/s003329172300140x · Cited by 14
Gender differences in the relationship between blood pressure and body mass index during adolescence
Kawada, N., Nakanishi, K., Ohama, T., Nishida, M., Yamauchi‐Takihara, K., & Moriyama, T. (2014) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2014.07.001 · Cited by 14
Koch, C. E., Göddeke, S., Krüger, M., & Tups, A. (2012) · Journal of Comparative Physiology B · doi:10.1007/s00360-012-0699-y · Cited by 14
Ibrahim, B. A., Alenazi, F., & Briski, K. P. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.10.068 · Cited by 14
Ruigrok, S. R., Kotah, J. M., Kuindersma, J. E., Speijer, E., van Irsen, A. A. S., la Fleur, S. E., & Kőrösi, A. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100360 · Cited by 15
Paraventricular Nucleus Sim1 Neuron Ablation Mediated Obesity Is Resistant to High Fat Diet
Dong, X., Roizen, J. D., Lai, M., Gandhi, N. M., & Kublaoui, B. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081087 · Cited by 14
Oleic acid stimulates monoamine efflux through PPAR-α: Differential effects in diet-induced obesity
Jagannathan, L., Socks, E., Balasubramanian, P., McGowan, R., Herdt, T. M., Kianian, R., MohanKumar, S. M. J., & MohanKumar, P. S. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117867 · Cited by 13
Dadak, S., Beall, C., Walker, J. M. V., Soutar, M. P. M., McCrimmon, R. J., & Ashford, M. L. J. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2016.12.053 · Cited by 14
Neuroendocrine regulation of hunger, satiety and maintenance of energy balance
González-Hita, M. E., Macias, K. G. A., & Enríquez, S. S. (2006) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 14
PPAR-γ action: it's all in your head
Myers, M. G., & Burant, C. (2011) · Nature Medicine · doi:10.1038/nm0511-544 · Cited by 13
Metabolic and humoral mechanisms of feeding and genesis of the ATP/ADP/AMP concept
Nicolaı̈dis, S. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.04.058 · Cited by 13
Lizarbe, B., Lei, H., Duarte, J. M. N., Lanz, B., Cherix, A., & Rolf Gruetter, A. (2018) · Magnetic Resonance in Medicine · doi:10.1002/mrm.27129 · Cited by 13
Yang, B., Bassols, A., Saco, Y., & Miguel Pérez-enciso, A. (2011) · Genetics Selection Evolution · doi:10.1186/1297-9686-43-28 · Cited by 16
Editorial: Neuroendocrine Control of Feeding Behavior
Luquet, S. H., Vaudry, H., & Granata, R. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00399 · Cited by 13
Maeshiro, T. (2018) · SICE Journal of Control Measurement and System Integration · doi:10.9746/jcmsi.11.381 · Cited by 12
Outcomes associated with timing of maintenance treatment for COPD exacerbation.
Dalal, A. A., Shah, M. B., D’Souza, A. O., Dhamane, A. D., & Crater, G. (2012) · PubMed · Cited by 10
Beyond Hunger: The Structure, Signaling, and Systemic Roles of Ghrelin
Polishchuk, H., Guzik, K., & Kantyka, T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262210996 · Cited by 16
Limited cheese intake reduces HPA axis and behavioral stress responses in male rats
Fourman, S. M., Buesing, D. R., Girvin, S., Nashawi, H., & Ulrich‐Lai, Y. M. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113614 · Cited by 11
Role of hypothalamic autophagy in the control of whole body energy balance
Kim, M.-S., Quan, W., & Lee, M. (2013) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-013-9257-5 · Cited by 12
Liu, H. Y., Zheng, G., Zhu, H., & Woldegiorgis, G. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2007.06.026 · Cited by 11
Brain lipid sensing and the neural control of energy balance
Cruciani‐Guglielmacci, C., Stunff, H. L., & Magnan, C. (2024) · Biochimie · doi:10.1016/j.biochi.2024.05.020 · Cited by 13
[Macronutrients, food intake and body weight; the role of fat].
Carrillo, J. A.-B., Torregrosa, M. D., Almendros, M. M., López‐Millán, B., Burgos, M. A., & Muñoz, E. M. D. V. (2014) · PubMed · doi:10.3305/nh.2015.31.1.8439 · Cited by 10
Panickar, K. S., & Bhathena, S. J. (2009) · Frontiers in neuroscience · doi:10.1201/9781420067767-c18 · Cited by 10
Lipid-Induced Peroxidation in the Intestine Is Involved in Glucose Homeostasis Imbalance in Mice
Sérino, M., Waget, A., Marsollier, N., Masseboeuf, M., Payros, G., Gallou‐Kabani, C., Denom, J., Lacombe, A., Thiers, J., Nègre‐Salvayre, A., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021184 · Cited by 10
Marantz, P. R. (2010) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2010.526846 · Cited by 9
Liu, L., Wang, X., Jiao, H., & Lin, H. (2017) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2017.02.018 · Cited by 10
He, Y., Zhang, C., Wu, S., Li, K., Zhang, S., Tian, M., Chen, C., Liu, D., Yang, G., Li, L., et al. (2024) · Metabolism · doi:10.1016/j.metabol.2024.156046 · Cited by 10
Mutsnaini, L., Yang, J., Kim, J., Kim, C.-S., Lee, C.-H., Kim, M., Park, T., Goto, T., & Yu, R. (2021) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-020-0220-5 · Cited by 8
Saliva cortisol responses to altered plasma PUFA patterns in guinea pigs
Nemeth, M., Millesi, E., Wagner, K., & Wallner, B. (2018) · British Journal Of Nutrition · doi:10.1017/s0007114518002660 · Cited by 8
Your brain on fat: dietary-induced obesity impairs central nutrient sensing
Schwartz, G. J. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00177.2009 · Cited by 8
Self-citationRole of saturated fatty acid metabolism in posttranslational modifications of the Tau protein
García-Cruz, V. M., Coria, R., & Arias, C. (2025) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-025-05275-2 · Cited by 7
Zhan, H., Wang, W., Ge, Y., Liang, Y., Wang, J., Xu, Y., Wu, S., Peng, L., & He, Z. (2024) · Food & Function · doi:10.1039/d4fo00452c · Cited by 8
Sleep, Circadian Rhythms and Metabolism
Maury, E., Ramsey, K. M., & Bass, J. T. (2010) · Springer eBooks · doi:10.1007/978-1-4419-1607-5_13 · Cited by 12
A System Description Model with Fuzzy Boundaries
Maeshiro, T., Ozawa, Y., & Maeshiro, M. (2017) · Lecture notes in computer science · doi:10.1007/978-3-319-58524-6_31 · Cited by 7
de Mello, P. H., Araújo, B. C., Venturieri, R. L. L., & Moreira, R. G. (2011) · Aquaculture International · doi:10.1007/s10499-011-9466-4 · Cited by 7
DiNicolantonio, J. J., McCarty, M. F., & O’Keefe, J. H. (2019) · Open Heart · doi:10.1136/openhrt-2018-000897 · Cited by 7
Regulation of Peripheral Metabolism by Substrate Partitioning in the Brain
Moreno, C. L., Yang, L. C., Dacks, P. A., Isoda, F., Poplawski, M. M., & Mobbs, C. V. (2013) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2012.11.007 · Cited by 8
Giant Island Mice Exhibit Widespread Gene Expression Changes in Key Metabolic Organs
Nolte, M. J., Jing, P., Dewey, C. N., & Payseur, B. A. (2020) · Genome Biology and Evolution · doi:10.1093/gbe/evaa118 · Cited by 6
Diet-Induced Metabolic Dysfunction of Hypothalamic Nutrient Sensing in Rodents
Arrieta‐Cruz, I., Torres-Ávila, B. S., Martínez‐Coria, H., López-Valdés, H. E., & Juárez, R. G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073958 · Cited by 6
Endocannabinoids in Energy Homeostasis and Metabolic Disorders
Matias, I., Marzo, V. D., & Köfalvi, A. (2007) · Springer eBooks · doi:10.1007/978-0-387-74349-3_14 · Cited by 6
Caloric restriction diminishes the pressor response to static exercise
Florian, J. P., Baisch, F. J., Heer, M. A., & Pawelczyk, J. A. (2016) · Extreme Physiology & Medicine · doi:10.1186/s13728-016-0043-3 · Cited by 6
Metabolic inflammation at the adipose-brain axis
Mateus-Gomes, S., Al-Sayyar, A., Lobey, B., Nadjar, A., Rua, R., & Ahmad, R. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1795058 · Cited by 5
Glutaredoxin1 knockout promotes high-fat diet-induced obesity in male mice but not in female ones
Zou, X., Ahmad, M. I., Zhao, D., Zhang, M., & Li, C. (2021) · Food & Function · doi:10.1039/d1fo01241j · Cited by 5
Neuroendocrine Regulation of Food Intake
Watts, A. G. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-375097-6.10014-9 · Cited by 6
Autophagy as a therapeutic linchpin in metabolic diseases and obesity-associated diabetes
Vakili, O., Klionsky, D. J., Reiter, R. J., Ren, J., Deshpande, A., Ahn, K. S., Cho, W., Hushmandi, K., & Kumar, A. P. (2026) · Autophagy · doi:10.1080/15548627.2026.2636096 · Cited by 7
Taste receptor type 1 member 3 enables western diet-induced anxiety in mice
Song, J. W., Lee, K.-H., Seong, H., Shin, D., & Shon, W.-J. (2023) · BMC Biology · doi:10.1186/s12915-023-01723-x · Cited by 4
Fat Metabolism in Insulin Resistance and Type 2 Diabetes
Duez, H., & Lewis, G. F. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-043-4_4 · Cited by 4
Richard, D., & Timofeeva, E. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374387-9.00024-6 · Cited by 4
Joly‐Amado, A., Soty, M., Philippe, E., Lacombe, A., Castel, J., Pillot, B., Vily‐Petit, J., Zitoun, C., Mithieux, G., & Magnan, C. (2022) · Journal of Nutrition · doi:10.1093/jn/nxac097 · Cited by 4
Endocannabinoid system and its role in energy regulation
Matias, I., & Marzo, V. D. (2006) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.1.4.557 · Cited by 4
Morcos, J. A., Ebeid, A. M., Khodeir, S. A., & El-Azab, G. A. (2017) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.1000759 · Cited by 3
Sleep disorders contribute to the development of dementia and Alzheimer’s disease
Błaszczyk, J. W. (2023) · Exploration of neuroscience · doi:10.37349/en.2023.00022 · Cited by 4
Association between sleep behaviors and adiposity indices among U.S. adults: a cross-sectional study
Xu, S., Lin, J. M., Xu, Q., Zhao, K., & Xiao, J. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1526422 · Cited by 3
C75, a Fatty Acid Synthase (FAS) Inhibitor
López, M., & Diéguez, C. (2007) · Recent Patents on Endocrine Metabolic & Immune Drug Discovery · doi:10.2174/187221407779814615 · Cited by 3
Zhang, M., Jiang, X., Qu, M., Gu, H., Sha, Q., & Hua, F. (2018) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s179346 · Cited by 3
Glucose and fat sensing in the human hypothalamus
van Opstal, A. M. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-820683-6.00024-5 · Cited by 3
Arboix-Calas, F. (2014) · Éducation et socialisation · doi:10.4000/edso.1002 · Cited by 3
Kul, K. (2019) · Open Access Journal of Endocrinology · doi:10.23880/oaje-16000143 · Cited by 3
The Unrestrained Overeating Behavior and Clinical Perspective
Engin, A. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-63657-8_6 · Cited by 3
Neuron stress-related genes serve as new biomarkers in hypothalamic tissue following high fat diet
Liang, C., 王雪芹, 苏建彬, Qi, F., Chen, T., Shang, Y., Li, Y., Li, Y., Su, S., Zhang, D., et al. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1443880 · Cited by 3
mTORC1 and mTORC2 in Energy Homeostasis
Cornu, M., & Hall, M. N. (2010) · The Enzymes · doi:10.1016/s1874-6047(10)28013-7 · Cited by 3
The hypothalamus and energy balance
Benedini, S. (2009) · Sport Sciences for Health · doi:10.1007/s11332-009-0079-5 · Cited by 3
Hypothalamic mitochondria in energy homeostasis and obesity
Guo, X., Wu, L., Wang, W., Medeiros, D. M., Clarke, S. L., Lucas, E. A., Smith, B. J., Chowanadisai, W., & Lin, D. (2016) · Integrative Molecular Medicine · doi:10.15761/imm.1000209 · Cited by 3
Body Weight and Appetite Regulation)
Machado, M. V., & Ulate-Montero, G. (2010) · Acta Médica Costarricense · Cited by 3
Hypothalamic AgRP neurons and the regulation of appetite and body weight: A review
Wang, P., & Zhang, G. (2018) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/n972018-00413 · Cited by 2
Hypothalamic Microinflammation: New Paradigm In Obesity And Metabolic Disease
Meiliana, A., Dewi, N. M., & Wijaya, A. (2020) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v12i3.1235 · Cited by 2
Non-alcoholic fatty liver disease and metabolic syndrome in childhood
Vlasov, N. N., & Корниенко, Е. А. (2020) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-183-11-51-61 · Cited by 4
Rahmanian, M., Yagin, N. L., & Alizadeh, M. (2020) · Galen Medical Journal · doi:10.31661/gmj.v9i0.1721 · Cited by 3
Barrios, V., Martos‐Moreno, G. Á., Frago, L. M., Chowen, J. A., & Argente, J. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6039-9_16 · Cited by 3
L-diabetes – causes, pathogenesis and therapy
Liebel, F.-P., & Zimmermann, E. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2006.02.048 · Cited by 3
Intestinal Lipids as Signaling Molecules
Ahima, R. S. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.05.030 · Cited by 3
Xi, D., Roizen, J. D., Lai, M., Gandhi, N. M., & Kublaoui, B. M. (2014) · PLoS ONE · doi:10.1371/annotation/9239a129-5677-43b0-8fe1-0c1e75e988df · Cited by 3
Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticityPreprint
Thomas, W. R., Richter, T. A., O’Neil, E. T., Baldoni, C., Corthals, A., von Elverfeldt, D., Nieland, J. D., Dechmann, D. K. N., Hunter, R. G., & Dávalos, L. M. (2024) · eLife · doi:10.7554/elife.100788 · Cited by 3
Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticityPreprint
Thomas, W. R., Richter, T. A., O’Neil, E. T., Baldoni, C., Corthals, A., von Elverfeldt, D., Nieland, J. D., Dechmann, D. K. N., Hunter, R. G., & Dávalos, L. M. (2024) · eLife · doi:10.7554/elife.100788.1 · Cited by 3
Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity
Thomas, W. R., Richter, T. A., O’Neil, E. T., Baldoni, C., Corthals, A., von Elverfeldt, D., Nieland, J. D., Dechmann, D. K. N., Hunter, R. G., & Dávalos, L. M. (2025) · eLife · doi:10.7554/elife.100788.3 · Cited by 2
Review: Keystone issues in ruminant science I. Feed intake control in ruminants
Pittroff, W., & Kothmann, M. M. (2025) · animal · doi:10.1016/j.animal.2025.101553 · Cited by 2
Dysfonctions du système nerveux sympathique et de la signalisation catécholaminergique chez l’obèse
Lafontan, M. (2013) · Obésité · doi:10.1007/s11690-013-0409-2 · Cited by 2
Les acides gras : molécules informatives du contrôle nerveux de l’homéostasie énergétique
Migrenne, S., Cruciani‐Guglielmacci, C., & Magnan, C. (2007) · Cahiers de Nutrition et de Diététique · doi:10.1016/s0007-9960(07)88756-6 · Cited by 2
A novel Transcript is Up‐Regulated by Fasting in the Hypothalamus and Enhances Insulin Signalling
Chai, B., Li, J., Fritze, D. M., Zhang, W., Xia, Z., & Mulholland, M. W. (2012) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2012.02378.x · Cited by 2
Détection centrale des acides gras et contrôle du bilan d’énergie
Migrenne, S., Cruciani‐Guglielmacci, C., & Magnan, C. (2011) · Cahiers de Nutrition et de Diététique · doi:10.1016/j.cnd.2011.06.006 · Cited by 2
Miller, K. J., & Azzara, A. V. (2008) · Molecular Interventions · doi:10.1124/mi.8.2.4 · Cited by 2
Loss of Autophagy in Hypothalamic Neurons May Be Involved in the Pathogenesis of Obesity
Ávalos, Y., Hernández‐Cáceres, M. P., Toledo, L., & Morselli, E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812146-7.00013-5 · Cited by 2
Role of bioactive lipids in obesity
Salsinha, A. S., Rodríguez-Alcalá, L. M., Pimentel, L. L., & Pintado, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824043-4.00012-9 · Cited by 2
Insights into the mechanisms of body weight control
Pereira, S. (2025) · AJP Advances in Physiology Education · doi:10.1152/advan.00091.2025 · Cited by 1
Targeting Gβγ subunits in hypothalamic AgRP neurons to treat obesity
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Metadata
- Authors
- Lam, T. K. T., Schwartz, G. J., & Rossetti, L.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Rossetti, Luciano
- Venue
- Nature Neuroscience
- Published
- 2005-04-26
- Volume
- 8
- Issue
- 5
- Pages
- 579-584
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W1977275538
- Cited by
- 478
- References
- 82
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 14 · 2023: 9 · 2022: 10 · 2021: 18 · 2020: 20 · 2019: 14 · 2018: 16 · 2017: 28 · 2016: 17 · 2015: 24 · 2014: 27 · 2013: 34 · 2012: 39
- FWCI
- 3.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (P01AG021654, AG 21654, T32AG023475)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK-48321, DK-47208, R01DK047208, DK20541, DK-45024)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Keywords
- hypothalamus, fatty acid sensing, fatty acid metabolism, nutrient availability, metabolic signaling, nutritional status, energy homeostasis, fuel availability
- MeSH terms
- Acyl Coenzyme A, Animals, Appetite Regulation, Energy Metabolism, Fatty Acids, Humans, Hypothalamus, Insulin Resistance, Obesity, Signal Transduction, Feedback, Physiological
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