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Cited by 774

The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.

DNA repair, genome stability and cancer: a historical perspective

Open access
Jeggo, Penny A., Pearl, Laurence H., Carr, Antony M.·2016·Nature Reviews Cancer

Abstract

The multistep process of cancer progresses over many years. The prevention of mutations by DNA repair pathways led to an early appreciation of a role for repair in cancer avoidance. However, the broader role of the DNA damage response (DDR) emerged more slowly. In this Timeline article, we reflect on how our understanding of the steps leading to cancer developed, focusing on the role of the DDR. We also consider how our current knowledge can be exploited for cancer therapy.

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Crossref · 10.1038/nrc.2015.4

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Metadata

Authors
Jeggo, P. A., Pearl, L. H., & Carr, A. M.
Venue
Nature Reviews Cancer
Published
2015-12-15
Volume
16
Issue
1
Pages
35-42
ISSN
  • 1474-175X (ISSN-L)
  • 1474-1768
OpenAlex
W2217722934
Cited by
774
References
95
FWCI
3.44
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: DNA repair, genome stability and cancer: a historical perspective. https://app.cochat.ai/papers/10.1038/nrc.2015.4
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Jeggo, P. A., Pearl, L. H., & Carr, A. M. (2016). DNA repair, genome stability and cancer: a historical perspective. Nature Reviews Cancer. https://doi.org/10.1038/nrc.2015.4

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.