RAS oncogenes: the first 30 years

Malumbres, Marcos, Barbacid, Mariano·2003·Nature Reviews Cancer

Cited by (1,002)

Items 501–600 of 1,002

  1. Ras Dimer Formation as a New Signaling Mechanism and Potential Cancer Therapeutic Target
    Mo Chen, Alec Peters, Tao Huang, Xiaolin Nan · 2015 · Mini-Reviews in Medicinal Chemistry
  2. Selective targeting of point-mutated KRAS through artificial microRNAs
    Mario Acunzo, Giulia Romano, Giovanni Nigita, Dario Veneziano, Luigi Fattore, Alessandro Laganà, Nicola Zanesi, Paolo Fadda, Matteo Fassan, Lara Rizzotto et al. · 2017 · Proceedings of the National Academy of Sciences
  3. Targeting KRAS mutant lung cancer: light at the end of the tunnel
    Matthias Drosten, Mariano Barbacid · 2021 · Molecular Oncology
  4. Biliverdin reductase: a target for cancer therapy?
    Peter Gibbs, Tihomir Miralem, Mahin D. Maines · 2015 · Frontiers in Pharmacology
  5. DNA Methylation and Cancer Pathways in Gastrointestinal Tumors
    Hiromu Suzuki, Takashi Tokino, Yasuhisa Shinomura, Kohzoh Imai, Minoru Toyota · 2008 · Pharmacogenomics
  6. Biodegradable Nanocapsules as siRNA Carriers for Mutant K‐Ras Gene Silencing of Human Pancreatic Carcinoma Cells
    Guimiao Lin, Rui Hu, Wing‐Cheung Law, Chih‐Kuang Chen, Yucheng Wang, Hui Li Chin, Quoc Toan Nguyen, Cheng Kee Lai, Ho Sup Yoon, Xiaomei Wang et al. · 2013 · Small
  7. Prospective–Retrospective Biomarker Analysis for Regulatory Consideration: white Paper from the Industry Pharmacogenomics Working Group
    Scott Donald Patterson, Nadine Cohen, Maha Karnoub, Sharada L. Truter, Eileen Emison, Shirin Khambata‐Ford, Brian B. Spear, Ekopimo Okon Ibia, Rizwana Sproule, Diane M. Barnes et al. · 2011 · Pharmacogenomics
  8. Prostatic intraepithelial neoplasia and intestinal metaplasia in prostates of probasin‐RAS transgenic mice
    Alexis Scherl, Jiufeng Li, Robert D. Cardiff, Nicole Schreiber‐Agus · 2004 · The Prostate
  9. Ras signaling is essential for skin development
    Drosten, M, Lechuga, C G, Barbacid, M · 2014 · Oncogene
  10. Integrative Analysis of Cancer-Related Signaling Pathways
    T. Keßler, Hendrik Hache, Christoph Wierling · 2013 · Frontiers in Physiology
  11. Investigating regulated signaling pathways in therapeutic targeting of non-small cell lung carcinoma
    Manzar Alam, Gulam Mustafa Hasan, Sayed M. Eldin, Mohd Adnan, Muhammad Bilal Riaz, Asimul Islam, Ilyas Khan, Md. Imtaiyaz Hassan · 2023 · Biomedicine & Pharmacotherapy
  12. Breakthrough in RAS targeting with pan-RAS(ON) inhibitors RMC-7977 and RMC-6236
    Panagiotis Filis, Dimitrios Salgkamis, Alexios Matikas, Ioannis Zerdes · 2024 · Drug Discovery Today
  13. Targeting PKCε by miR‐143 regulates cell apoptosis in lung cancer
    Ni Zhang, Yunshu Su, Lijun Xu · 2013 · FEBS Letters
  14. KRAS mutation testing in clinical practice
    Sudhir Perincheri, Pei Hui · 2014 · Expert Review of Molecular Diagnostics
  15. Increased BRAF Heterodimerization Is the Common Pathogenic Mechanism for Noonan Syndrome-Associated RAF1 Mutants
    Xue Wu, Jiani C. Yin, Jeremy A. Simpson, Kyoung-Han Kim, Shengqing Stan Gu, Jenny H. Hong, Peter E. Bayliss, Peter H. Backx, Benjamin G. Neel, Toshiyuki Araki · 2012 · Molecular and Cellular Biology
  16. Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines
    Jens Bunt, Talitha G. de Haas, Nancy E. Hasselt, Danny A. Zwijnenburg, Jan Köster, Rogier Versteeg, Marcel Kool · 2010 · Molecular Cancer Research
  17. Oligonucleotide-Based Theranostic Nanoparticles in Cancer Therapy
    Reza Shahbazi, Bülent Özpolat, Kezban Ulubayram · 2016 · Nanomedicine
  18. Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms
    H Y Lau, Jingyi Tang, Patrick J. Casey, Mei Wang · 2017 · Oncogene
  19. RAS genes in colorectal carcinoma: pathogenesis, testing guidelines and treatment implications
    Omer Abdelaziz Mohammed Saeed, Antonio Lopez-beltran B, Kurt W. Fisher, Marina Scarpelli, Rodolfo Montironi, Alessia Cimadamore, Francesco Massari, Matteo Santoni, Liang Cheng C · 2018 · Journal of Clinical Pathology
  20. Molecular genetics of colorectal cancer: An overview
    Irfan M. Hisamuddin, Vincent W. Yang · 2006 · Current Colorectal Cancer Reports
  21. An Update on the Biology of RAS/RAF Mutations in Colorectal Cancer
    Mandayam O. Nandan, Vincent W. Yang · 2011 · Current Colorectal Cancer Reports
  22. Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
    Andrew J. Stout, Xiaoli Zhang, Sophia M. Letcher, Miriam L. Rittenberg, Michelle Shub, Kristin M. Chai, Maya Kaul, David Lee Kaplan · 2024 · Cell Reports Sustainability
  23. A Central Role for Ras1 in Morphogenesis of the Basidiomycete Schizophyllum commune
    Nicole Knabe, Elke‐Martina Jung, Daniela Freihorst, Florian Hennicke, J. Stephen Horton, Erika Kothe · 2013 · Eukaryotic Cell
  24. Amino Derivatives of Indole As Potent Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase
    Mei‐Lin Go, Jo Lene Leow, Suresh Kumar Gorla, Andreas Schüller, Mei Wang, Patrick J. Casey · 2010 · Journal of Medicinal Chemistry
  25. Time-Dependent Sensitivity Analysis of Biological Networks: Coupled MAPK and PI3K Signal Transduction Pathways
    Dawei Hu, Jian‐Min Yuan · 2006 · The Journal of Physical Chemistry A
  26. Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern
    Sharon Eisenberg, Alison J. Beckett, Ian A. Prior, Frank J. Dekker, Christian Hedberg, Herbert Waldmann, Marcelo Ehrlich, Yoav I. Henis · 2011 · Molecular and Cellular Biology
  27. Ras mutational status is a biomarker for resistance to EGFR inhibitors in colorectal carcinoma.
    Wolfram C. M. Dempke, Volker Heinemann · 2010 · PubMed
  28. Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells
    Danyel G. J. Jennen, Ainhoa Ruiz‐Aracama, Christina Magkoufopoulou, Ad Peijnenburg, Arjen Lommen, Joost H.M. van Delft, Jos C. S. Kleinjans · 2011 · BMC Systems Biology
  29. Biomarker in Colorectal Cancer
    Marta Schirripa, Heinz‐Josef Lenz · 2016 · The Cancer Journal
  30. A thirty-year quest for a role of R-Ras in cancer: from an oncogene to a multitasking GTPase
    Wai Nam Liu, Mingfei Yan, Andrew Man-Lok Chan · 2017 · Cancer Letters
  31. Recurrence‐associated gene signature optimizes recurrence‐free survival prediction of colorectal cancer
    Xianglong Tian, Xiaoqiang Zhu, Tingting Yan, Chenyang Yu, Chaoqin Shen, Ye Hu, Jie Hong, Haoyan Chen, Jing‐Yuan Fang · 2017 · Molecular Oncology
  32. Neoantigens in Hematologic Malignancies
    Melinda Ann Biernacki, Marie Bleakley · 2020 · Frontiers in Immunology
  33. BRAFV600E Efficient Transformation and Induction of Microsatellite Instability Versus KRASG12V Induction of Senescence Markers in Human Colon Cancer Cells
    Eftychia Oikonomou, Eleni Makrodouli, Maria Evagelidou, Tobias Joyce, Lesley Probert, Alexander Pintzas · 2009 · Neoplasia
  34. Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation
    Mathiasen, D P, Egebjerg, C, Andersen, S H, Rafn, B, Puustinen, P, Khanna, A, Daugaard, M, Valo, E, Tuomela, S, Bøttzauw, T et al. · 2012 · Oncogene
  35. More to the RAS Story: KRAS G12C Inhibition, Resistance Mechanisms, and Moving Beyond KRAS G12C
    Lietman, Caressa D., Johnson, Melissa L., McCormick, Frank, Lindsay, Colin R. · 2022 · American Society of Clinical Oncology Educational Book
  36. Role of RAS signaling in ovarian cancer
    Lubna Therachiyil, Anjana Anand, Abdullah Azmi, Ajaz Ahmad Bhat, Hesham Mohamed Korashy, Shahab Uddin M.S. · 2022 · F1000Research
  37. p27 kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability
    Linda Fabris, Stefania Berton, Ilenia Pellizzari, Ilenia Segatto, Sara D’Andrea, Joshua Armenia, Riccardo Bomben, Mónica Schiappacassi, Valter Gattei, Mark R. Philips et al. · 2015 · Proceedings of the National Academy of Sciences
  38. EGFR, HER-2 and KRAS in Canine Gastric Epithelial Tumors: A Potential Human Model?
    Rossella Terragni, Andrea Casadei Gardini, Silvia Sabattini, Giuliano Bettini, Dino Amadori, Chiara Talamonti, Massimo Vignoli, Laura Capelli, Jimmy H. Saunders, Marianna Ricci et al. · 2014 · PLoS ONE
  39. A Systems Perspective of Ras Signaling in Cancer
    Edward C. Stites, Kodi S. Ravichandran · 2009 · Clinical Cancer Research
  40. Differential Oncogenic Ras Signaling and Senescence in Tumor Cells
    Teeru Bihani, Douglas X. Mason, Tonya J. Jackson, Shang Chiung Chen, Benjamin Boettner, Athena W. Lin · 2004 · Cell Cycle
  41. Synthesis and Application of Fluorescence‐Labeled Ras‐Proteins for Live‐Cell Imaging
    Reinhard Reents, Melanie Wagner, Jürgen Kuhlmann, Herbert Waldmann · 2004 · Angewandte Chemie International Edition
  42. Clinical impact of STK11 mutation in advanced-stage non-small cell lung cancer
    Rosellini, Pietro, Amintas, Samuel, Caumont, Charline, Veillon, Rémi, Galland-Girodet, Sigolène, Cuguillière, Alain, Nguyen, Laurent, Domblides, Charlotte, Gouverneur, Amandine, Merlio, Jean-Philippe et al. · 2022 · European Journal of Cancer
  43. Somatic HRAS p.G12S Mutation Causes Woolly Hair and Epidermal Nevi
    Jonathan L. Levinsohn, Joyce M. C. Teng, Brittany G. Craiglow, Erin C. Loring, T Andrew Burrow, Shrikant Mane, John D. Overton, Richard P. Lifton, Jennifer Madison McNiff, Anne W. Lucky et al. · 2013 · Journal of Investigative Dermatology
  44. Herpesviruses: Hijacking the Ras signaling pathway
    Harilaos Filippakis, Demetrios A. Spandidos, George Sourvinos · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  45. Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation
    Lothar Gremer, Alessandro De Luca, Torsten Merbitz-Zahradnik, Bruno Dallapiccola, Susanne Morlot, Marco Tartaglia, Kerstin Kutsche, Mohammad Reza Ahmadian, Georg Rosenberger · 2009 · Human Molecular Genetics
  46. Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer
    Reo Maruyama, Kimishige Akino, Minoru Toyota, Hiromu Suzuki, Takashi Imai, Mutsumi Ohe-Toyota, Eiichiro Yamamoto, Masanori Nojima, Tomoko Fujikane, Yasushi Sasaki et al. · 2008 · Carcinogenesis
  47. Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoforms
    Saeideh Nakhaei‐Rad, Fereshteh Haghighi, Parivash Nouri, Soheila Rezaei Adariani, Jana Lissy, Neda S. Kazemein Jasemi, Radovan Dvorský, Mohammad Reza Ahmadian · 2018 · Critical Reviews in Biochemistry and Molecular Biology
  48. Inflammatory signaling in genomically instable cancers
    Francien Talens, Marcel A.T.M. van Vugt · 2019 · Cell Cycle
  49. RAS as a positive predictive biomarker: focus on lung and colorectal cancer patients
    Umberto Malapelle, Francesco Passiglia, Chiara Cremolini, Maria Lucia Reale, Francesco Pepe, Pasquale Pisapia, Antonio Avallone, Diego Luigi Cortinovis, Alfonso De Stefano, Matteo Fassan et al. · 2021 · European Journal of Cancer
  50. Current Perspectives and Novel Strategies of NRAS-Mutant Melanoma
    Alejandro García‐Álvarez, Carolina Ortiz, Eva Muñoz‐Couselo · 2021 · OncoTargets and Therapy
  51. B-Raf and Ha-ras mutations in chemically induced mouse liver tumors
    Maike Jaworski, Albrecht Buchmann, Peter O. Bauer, Olaf Rieß, Michael Schwarz · 2004 · Oncogene
  52. Upregulation of the PI3K/Akt Pathway in the Tumorigenesis of Canine Thyroid Carcinoma
    Miguel A. Lorenzo Campos, M.M.J. Kool, Sylvie Daminet, Richard Ducatelle, Gerard R. Rutteman, H.S. Kooistra, Sara Galac, Jan A. Mol · 2014 · Journal of Veterinary Internal Medicine
  53. Neurofibroma development in NF1 – insights into tumour initiation
    Simona Parrinello, Alison C. Lloyd · 2009 · Trends in Cell Biology
  54. The small G-protein RalA stimulates metastasis of transformed cells
    Elena M. Tchevkina, Larissa S. Agapova, Natalia A. Dyakova, A. Martinjuk, Andrei V. Komelkov, Alexander G. Tatosyan · 2004 · Oncogene
  55. Discovery of Raf Family Is a Milestone in Deciphering the Ras-Mediated Intracellular Signaling Pathway
    Jingtong Zhao, Zhijun Luo · 2022 · International Journal of Molecular Sciences
  56. Hedgehog Signaling and Pancreatic Tumor Development
    Matthias Lauth, Rune Toftgård · 2011 · Advances in cancer research
  57. Molecular Predictors of Response to Chemotherapy in Colorectal Cancer
    Rodrigo Dienstmann, Eduardo Vilar, Josep M. Tabernero · 2011 · The Cancer Journal
  58. Signaling pathways in follicular cell-derived thyroid carcinomas
    Mírian Romitti, Lucieli Ceolin, Débora Rodrigues Siqueira, Carla Vaz Ferreira, Simone Magagnin Wajner, Ana Luiza Maia · 2012 · International Journal of Oncology
  59. Proteins kinase Cɛ is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes
    M. Cecilia Caino, Cynthia López‐Haber, Jeewon Kim, Daria Mochly‐Rosen, Marcelo G. Kazanietz · 2011 · Oncogene
  60. Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells
    Vanessa González‐Pérez, David J. Reiner, Jamie K. Alan, Cicely E. Mitchell, Lloyd J. Edwards, Vladimir Khazak, Channing J. Der, Adrienne D. Cox · 2010 · Journal of Molecular Signaling
  61. New Strategies in Colorectal Cancer: Biomarkers of Response to Epidermal Growth Factor Receptor Monoclonal Antibodies and Potential Therapeutic Targets in Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Pathways
    Arvind N. Dasari, Wells A. Messersmith · 2010 · Clinical Cancer Research
  62. Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial
    Chih‐Jian Lih, David J. Sims, Robin D. Harrington, Eric C. Polley, Yingdong Zhao, Michele G. Mehaffey, Thomas D. Forbes, Biswajit Das, William D. Walsh, Vivekananda Datta et al. · 2015 · Journal of Molecular Diagnostics
  63. Role of estrogen and RAS signaling in repeated implantation failure
    Kwonho Hong, Youngsok Choi · 2018 · BMB Reports
  64. MicroRNA-1301 inhibits proliferation of human glioma cells by directly targeting N-Ras.
    Tongle Zhi, Kuan Jiang, Chuanzhuo Zhang, Xiupeng Xu, Weining Wu, Er Nie, Tianfu Yu, Xu Zhou, Zhongyuan Bao, Xin Jin et al. · 2017 · PubMed Central
  65. A Phase I Study of Dinaciclib in Combination With MK‐2206 in Patients With Advanced Pancreatic Cancer
    Adrian Gerard Murphy, MARIANNA L. ZAHURAK, Mirat Shah, Colin D. Weekes, Aaron Richard Hansen, Lillian L. Siu, Anna Spreafico, Noelle K. LoConte, Nicole M. Anders, T. Miles et al. · 2020 · Clinical and Translational Science
  66. synMuv verité—Myb comes into focus: Figure 1.
    Joseph S. Lipsick · 2004 · Genes & Development
  67. PD-1/PD-L1 Axis as a Potential Therapeutic Target for Multiple Sclerosis: A T Cell Perspective
    Haixia Li, Chao Zheng, Jinming Han, Jie Zhu, Shan Liu, Tao Jin · 2021 · Frontiers in Cellular Neuroscience
  68. An ERK1/2‐driven RNA‐binding switch in nucleolin drives ribosome biogenesis and pancreatic tumorigenesis downstream of RAS oncogene
    Muhammad S. Azman, Emilie L. Alard, Martin Dodel, Federica Capraro, Rupert Faraway, Maria Dermit, Wanling Fan, Alina Chakraborty, Jernej Ule, Faraz K. Mardakheh · 2023 · The EMBO Journal
  69. Small molecular inhibitors for KRAS-mutant cancers
    Xuan Wu, Wenping Song, Cheng Cheng, Ziyang Liu, Xiang Li, Yu Cui, Yao Gao, Li Ding · 2023 · Frontiers in Immunology
  70. G-quadruplexes in cancer-related gene promoters: from identification to therapeutic targeting
    Francesca Romano, Anna Di Porzio, Nunzia Iaccarino, Gelsomina Riccardi, Ritamaria Di Lorenzo, Sonia Laneri, Bruno Pagano, Jussara Amato, Antonio Randazzo · 2023 · Expert Opinion on Therapeutic Patents
  71. Properties of FDA-approved small molecule protein kinase inhibitors: A 2026 update
    Robert Jr. Roskoski · 2026 · Pharmacological Research
  72. Down-Regulation of miR-4500 Promoted Non-Small Cell Lung Cancer Growth
    Lei Zhang, Jianjun Qian, Yong Qiang, Hairong Huang, Changtian Wang, Demin Li, Biao Xu · 2014 · Cellular Physiology and Biochemistry
  73. Papillary mucinous metaplasia of the endometrium as a possible precursor of endometrial mucinous adenocarcinoma
    Su Hyun Yoo, Bong Hee Park, Jene Choi, Jin Young Yoo, Shin‐Wha Lee, Yong‐Man Kim, Kyu-Rae Kim · 2012 · Modern Pathology
  74. The cation‐dependent G‐proteins: In a class of their own
    Miriam-Rose Ash, Megan J. Maher, Jules Mitchell Guss, Mika Jormakka · 2012 · FEBS Letters
  75. Small Molecules Which Improve Pathogenesis of Myotonic Dystrophy Type 1
    Marta López-Morató, J. David Brook, Marzena Wojciechowska · 2018 · Frontiers in Neurology
  76. Detection of KRAS Mutations in Colorectal Carcinoma Patients with an Integrated PCR/Sequencing and Real-Time PCR Approach
    Pietro Carotenuto, Cristin Roma, Anna Maria Rachiglio, Fabiana Tatangelo, Carmine Pinto, Fortunato Ciardiello, Oscar Nappi, Vincenzo Rosario Iaffaioli, Gerardo Botti, Nicola Normanno · 2010 · Pharmacogenomics
  77. State of Melanoma
    Vikram C. Gorantla, John M. Kirkwood · 2014 · Hematology/Oncology Clinics of North America
  78. KRAS Mutations and Susceptibility to Cetuximab and Panitumumab in Colorectal Cancer
    Antonio Jimeno, Wells A. Messersmith, Fred R. Hirsch, Wilbur A. Franklin, S. Gail Eckhardt · 2009 · The Cancer Journal
  79. Statins augment efficacy of EGFR-TKIs in patients with advanced-stage non-small cell lung cancer harbouring KRAS mutation
    Ondřej Fiala, Miloš Pešek, Jindřich Fínek, Marek Minárik, Lucie Benešová, Zbyněk Bortlíček, Ondřej Topolčan · 2015 · Tumor Biology
  80. Tumour-related microRNAs functions in Caenorhabditis elegans
    Guillaume Jannot, Martin J. Simard · 2006 · Oncogene
  81. Cyclopentenediones, inhibitors of farnesyl protein transferase and anti-tumor compounds, isolated from the fruit of Lindera erythrocarpa Makino
    Hyun-Mi Oh, Sung-Kyu Choi, Ji Min Lee, Su Kyung Lee, Hak-Yung Kim, Dong Cho Han, Hwan-Mook Kim, Kwang‐Hee Son, Byoung‐Mog Kwon · 2005 · Bioorganic & Medicinal Chemistry
  82. From Concepts to Inhibitors: A Blueprint for Targeting Protein–Protein Interactions
    Seong Ho Hong, Thu Trang Nguyễn, Joseph F. Ongkingco, Alex Nazzaro, Paramjit S. Arora · 2025 · Chemical Reviews
  83. Oncogenic Ras and B-Raf Proteins Positively Regulate Death Receptor 5 Expression through Co-activation of ERK and JNK Signaling
    You-Take Oh, Ping Yue, Wei Zhou, Justin Micah Balko, Esther P. Black, Taofeek Kunle Owonikoko, Fadlo Raja Khuri, Shi‐Yong Sun · 2011 · Journal of Biological Chemistry
  84. Effects of sulfur dioxide derivatives on expression of oncogenes and tumor suppressor genes in human bronchial epithelial cells
    Guohua Qin, Ziqiang Meng · 2009 · Food and Chemical Toxicology
  85. Tnk1/Kos1 Knockout Mice Develop Spontaneous Tumors
    Sarasija Hoare, Kishalay Hoare, Mary K. Reinhard, Young Jae Lee, Sang-Churl Oh, William Stratford May · 2008 · Cancer Research
  86. KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer
    Marta Herreros‐Villanueva, Maximiliano Rodrigo, Manuel Claver, Pilar Múñiz, Enrique Lastra, Carlos García Girón, María Jesús Coma del Corral · 2010 · Molecular Biology Reports
  87. RASSF1A Deficiency Enhances RAS-Driven Lung Tumorigenesis
    Marianne Schmidt, Katharine R. Hobbing, Howard Donninger, Geoffrey J. Clark · 2018 · Cancer Research
  88. Design, Synthesis, and Evaluation of Novel p-(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex
    Wang Peng, Sun Zhi-yin, Qi Zhang, Sui-Qi Cheng, Shi‐Ke Wang, Xiaona Wang, Guotao Kuang, Xiaoxuan Su, Jia‐Heng Tan, Zhi‐Shu Huang et al. · 2018 · Journal of Medicinal Chemistry
  89. PTEN loss and KRAS activation cooperate in murine biliary tract malignancies
    Victoria L. Marsh, Emma Jane Davies, Geraint T. Williams, Alan Richard Clarke · 2013 · The Journal of Pathology
  90. Advances in the Treatment of Metastatic Colorectal Cancer
    Carla D. Kurkjian, Shivaani Kummar · 2009 · American Journal of Therapeutics
  91. Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes
    Begoña Sot, Elmar Behrmann, Stefan Raunser, Alfred Wittinghofer · 2012 · Proceedings of the National Academy of Sciences
  92. Regulation of H-ras Splice Variant Expression by Cross Talk between the p53 and Nonsense-Mediated mRNA Decay Pathways
    Jérôme Barbier, Martin Dutertre, Danielle Bittencourt, Gabriel Sanchez, Lise Gratadou, Pierre de la Grange, Didier Auboeuf · 2007 · Molecular and Cellular Biology
  93. Chromosome instability and deregulated proliferation: an unavoidable duo
    Courtney H. Coschi, Frederick A. Dick · 2012 · Cellular and Molecular Life Sciences
  94. The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling
    Marco Biancucci, G. Minasov, Avik Banerjee, Alfa Herrera, Patrick J. Woida, Matthew B. Kieffer, Lakshman K. Bindu, Maria Teresa Abreu‐Blanco, W.F. Anderson, Vadim Gaponenko et al. · 2018 · Science Signaling
  95. Drug library screen reveals benzimidazole derivatives as selective cytotoxic agents for KRAS-mutant lung cancer
    Iwao Shimomura, Akira Yokoi, Isaku Kohama, Minami Kumazaki, Yuji Tada, Koichiro Tatsumi, Takahiro Ochiya, Yusuke Yamamoto · 2019 · Cancer Letters
  96. A Review on Dietary Intervention in Obesity Associated Colon Cancer
    Nur Hazirah Roslan, Suzana Makpol, Yasmin Anum Mohd Yusof · 2019 · Asian Pacific Journal of Cancer Prevention
  97. Expression of Nras Q61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice
    Zhi Hong Wen, Adhithi Rajagopalan, Evan Flietner, Grant Yun, Marta Chesi, Quinlan Furumo, Robert T. Burns, Athanasios Papadas, Erik A. Ranheim, Adam C. Pagenkopf et al. · 2020 · Blood
  98. MicroRNA-377: A therapeutic and diagnostic tumor marker
    Iman Akhlaghipour, Negin Taghehchian, Amir Sadra Zangouei, Amirhosein Maharati, Reihaneh Alsadat Mahmoudian, Ehsan Saburi, Meysam Moghbeli · 2022 · International Journal of Biological Macromolecules
  99. The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis
    Mirco Menigatti, Elisa Cattaneo, Jacob Sabates–Bellver, Valery Vladimirovich Ilinsky, Philip Went, Federico Buffoli, Víctor E. Márquez, Josef Jiricny, Giancarlo Marra · 2009 · Molecular Cancer
  100. Reduction of Mouse Egg Surface Integrin Alpha9 Subunit (ITGA9) Reduces the Egg's Ability to Support Sperm-Egg Binding and Fusion1
    Ulyana Vjugina, Xiaoling Zhu, Eugene Oh, Nabal Jose Bracero, Janice P. Evans · 2009 · Biology of Reproduction