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The Pfam Protein Families Database

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PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

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A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

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A cell cycle regulator potentially involved in genesis of many tumor types

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PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors

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Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

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5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

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A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

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The complexity of prostate cancer: genomic alterations and heterogeneity

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Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome

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Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential

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Cancer stem cells and human malignant melanoma

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Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array

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High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization

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Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

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PVT1: A Rising Star among Oncogenic Long Noncoding RNAs

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PTMD: A Database of Human Disease-Associated Post-Translational Modifications

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4E-Binding Protein 1, A Cell Signaling Hallmark in Breast Cancer that Correlates with Pathologic Grade and Prognosis

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Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants

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Genomic Landscape of Copy Number Aberrations Enables the Identification of Oncogenic Drivers in Hepatocellular Carcinoma

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CancerMine: a literature-mined resource for drivers, oncogenes and tumor suppressors in cancer

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Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers

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Oncolytic Virotherapy and Immunogenic Cancer Cell Death: Sharpening the Sword for Improved Cancer Treatment Strategies

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DDX3, a DEAD Box RNA Helicase with Tumor Growth–Suppressive Property and Transcriptional Regulation Activity of the p21waf1/cip1 Promoter, Is a Candidate Tumor Suppressor

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SVDetect: a tool to identify genomic structural variations from paired-end and mate-pair sequencing data

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Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing eventsPreprint

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A mathematical model of breast cancer development, local treatment and recurrence

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Centrosomes and cancer: revisiting a long-standing relationship

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Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes

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Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases

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Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles

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Role of selection in fixation of gene duplications

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Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis

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Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolutionPreprint

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Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

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Chromosome Translocation, B Cell Lymphoma, and Activation-Induced Cytidine Deaminase

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Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts

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Precision Oncology: The Road Ahead

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Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell linePreprint

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Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

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Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancerPreprint

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Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis

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FOXM1 (Forkhead box M1) in Tumorigenesis

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Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present

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Application of Active and Kinase-Deficient Kinome Collection for Identification of Kinases Regulating Hedgehog Signaling

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Darwinian medicine: a case for cancer

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Models for prevention and treatment of cancer: Problems vs promises

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Large-Scale Mutagenesis in p19ARF- and p53-Deficient Mice Identifies Cancer Genes and Their Collaborative Networks

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CancerGenes: a gene selection resource for cancer genome projects

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Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

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Phosphorylated 4E binding protein 1: A hallmark of cell signaling that correlates with survival in ovarian cancer

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What does physics have to do with cancer?

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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

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Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project

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Genomic rearrangements in inherited disease and cancer

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Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling

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Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences

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First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol

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From human genome to cancer genome: The first decadePreprint

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The Transcription Factor FOXM1 (Forkhead box M1)

Wierstra, I. (2013) · Advances in cancer research · doi:10.1016/b978-0-12-407173-5.00004-2 · Cited by 180

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

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Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer

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A biobank of patient-derived pediatric brain tumor models

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In-depth characterization of the microRNA transcriptome in a leukemia progression modelPreprint

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Minireview: RET: Normal and Abnormal Functions

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Computational approaches to identify functional genetic variants in cancer genomes

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A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

Brooks, A. N., Choi, P. S., de Waal, L. M., Sharifnia, T., Imielinski, M. B., Saksena, G., Pedamallu, C. S., Sivachenko, A., Rosenberg, M. W., Chmielecki, J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087361 · Cited by 173

New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome

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High-Resolution Single Nucleotide Polymorphism Array Analysis of Epithelial Ovarian Cancer Reveals Numerous Microdeletions and Amplifications

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Systematic genome instability screens in yeast and their potential relevance to cancer

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Functional Copy-Number Alterations in Cancer

Taylor, B. S., Barretina, J., Socci, N. D., DeCarolis, P., Ladanyi, M., Meyerson, M., Singer, S., & Sander, C. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003179 · Cited by 170

A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening

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Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing

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Clonal evolution in hematological malignancies and therapeutic implications

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Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct

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Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis

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The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components

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Chronotherapy and the molecular clock: Clinical implications in oncology☆

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Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences

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Somatic alterations in the human cancer genome

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Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer

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