p53 and E2f: partners in life and death

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., & Bradley, A. (1992) · Nature · doi:10.1038/356215a0 · Cited by 4,649

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki, M., & Reed, J. C. (1995) · Cell · doi:10.1016/0092-8674(95)90412-3 · Cited by 4,063

Network motifs: theory and experimental approaches

Alon, U. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2102 · Cited by 3,279

Live or let die: the cell's response to p53

Vousden, K. H., & Lü, X. (2002) · Nature reviews. Cancer · doi:10.1038/nrc864 · Cited by 3,231

A microRNA component of the p53 tumour suppressor network

He, L., He, X., Lim, L. P., de Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D., et al. (2007) · Nature · doi:10.1038/nature05939 · Cited by 2,692

PUMA, a Novel Proapoptotic Gene, Is Induced by p53

Nakano, K., & Vousden, K. H. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00214-3 · Cited by 2,315

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., & Tanaka, †. N. (2000) · Science · doi:10.1126/science.288.5468.1053 · Cited by 2,112

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Luo, J., Nikolaev, A. Y., Imai, S.-I., Chen, D., Su, F., Shiloh, A., Guarente, L., & Gu, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00524-4 · Cited by 2,081

Tumor spectrum analysis in p53-mutant mice

Jacks, T., Remington, L., Williams, B. O., Schmitt, E. M., Halachmi, S., Bronson, R. T., & Weinberg, R. A. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00002-6 · Cited by 2,051

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Canman, C. E., Lim, D.-S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., & Siliciano, J. D. (1998) · Science · doi:10.1126/science.281.5383.1677 · Cited by 2,042

Arabidopsis nucleoporin CPR5 controls trichome cell death through the core cell cycle regulator CKI

Peng, S., Sun, K., Guo, Y., Liu, Y., & Wang, S. (2019) · Plant Biology · doi:10.1111/plb.13068 · Cited by 15

Dysregulation of AKT3 along with a small panel of mRNAs stratifies high-grade serous ovarian cancer from both normal epithelia and benign tumor tissues

Yeganeh, P. N., Richardson, C. A., Bahrani-Mostafavi, Z., Tait, D. L., & Mostafavi, M. T. (2017) · Genes & Cancer · doi:10.18632/genesandcancer.164 · Cited by 15

miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma

Qin, H., Gui, Y., Ma, R., Zhang, H., Guo, Y., Ye, Y., Li, J., Zhao, L., & Wang, Y. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.671144 · Cited by 15

Actinomycin D Arrests Cell Cycle of Hepatocellular Carcinoma Cell Lines and Induces p53-Dependent Cell Death: A Study of the Molecular Mechanism Involved in the Protective Effect of IRS-4

Guijarro, L. G., Sanmartín-Salinas, P., Cuevas, E. P., Toledo-Lobo, M. V., Monserrat, J., Zoullas, S., Sáez, M. A., Álvarez-Mon, M. Á., Buján, J., Noguerales-Fraguas, F., et al. (2021) · Pharmaceuticals · doi:10.3390/ph14090845 · Cited by 15

Retinoblastoma-E2F Transcription Factor Interplay Is Essential for Testicular Development and Male Fertility

Mäkelä, J., & Toppari, J. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.903684 · Cited by 16

Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors

Lindström, L., Villoutreix, B. O., Lehn, S., Hellsten, R., Nilsson, E., Crneta, E., Olsson, R., & Alvarado-Kristensson, M. (2015) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-15-0063-t · Cited by 15

Post-translational Down-regulation of Melanoma Antigen-A11 (MAGE-A11) by Human p14-ARF Tumor Suppressor

Minges, J. T., Grossman, G., Zhang, P., Kafri, T., & Wilson, E. M. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.663641 · Cited by 15

Murine Double Minute Clone 2 309T/G and 285G/C Promoter Single Nucleotide Polymorphism as a Risk Factor for Breast Cancer: A Polish Experience

Piotrowski, P., Lianeri, M., Rubiś, B., Knuła, H., Rybczyńska, M., Grodecka-Gazdecka, S., & Jagodziński, P. P. (2012) · The International Journal of Biological Markers · doi:10.5301/jbm.2012.9140 · Cited by 14

Molecular connections of obesity and aging: a focus on adipose protein 53 and retinoblastoma protein

Chu, D., & Tao, Y. (2017) · Biogerontology · doi:10.1007/s10522-017-9698-4 · Cited by 14

System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia

Li, R., Wang, Y., Cheng, H., Liu, G., Cheng, T., Liu, Y., & Liu, L. (2017) · BMC Systems Biology · doi:10.1186/s12918-017-0467-4 · Cited by 14

Evaluation of the Cytotoxicity and Apoptotic Induction in Human Liver Cell Lines Exposed to Three Food Additives

El-Hefny, I. M., Al-Senosy, N. K., Hozayen, W. G., Ahmed, A. E., Diab, A. A., & Basal, W. T. (2020) · Recent Patents on Food Nutrition & Agriculture · doi:10.2174/2212798411666200217124630 · Cited by 14

Regulation of p53 and NF-κB transactivation activities by DGKζ in catalytic activity-dependent and -independent manners

Tanaka, T., Nakano, T., Hozumi, Y., Martelli, A. M., & Goto, K. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2021.118953 · Cited by 15

Human herpesvirus 6 (HHV-6) alters E2F1/Rb pathways and utilizes the E2F1 transcription factor to express viral genes

Sharon, E., Volchek, L., & Frenkel, N. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1308854110 · Cited by 14

Characterizing Genetic Transitions of Copy Number Alterations and Allelic Imbalances in Oral Tongue Carcinoma Metastasis

Morita, T., Uzawa, N., Mogushi, K., Sumino, J., Michikawa, C., Takahashi, K., Myo, K., Izumo, T., & Harada, K. (2016) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22395 · Cited by 14

Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex

Carrà, G., Crivellaro, S., Taulli, R., Guerrasio, A., Saglio, G. N., & Morotti, A. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17121997 · Cited by 14

Ameliorating Effect of Osteopontin on H2O2-Induced Apoptosis of Human Oligodendrocyte Progenitor Cells

Mazaheri, N., Peymani, M., Galehdari, H., Ghaedi, K., Ghoochani, A., Kiani‐Esfahani, A., & Nasr‐Esfahani, M. H. (2017) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-017-0563-4 · Cited by 14

E2F1 interacts with BCL‐xL and regulates its subcellular localization dynamics to trigger cell death

Vuillier, C., Lohard, S., Fétiveau, A., Allègre, J., Kayaci, C., King, L. E., Braun, F., Barillé‐Nion, S., Gautier, F., Dubrez, L., et al. (2017) · EMBO Reports · doi:10.15252/embr.201744046 · Cited by 14

Loss of circadian protein TIMELESS accelerates the progression of cellular senescence

Shen, X., Li, M., Mao, Z., & Yu, W. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.08.040 · Cited by 14

Expression and prognosis analyses of CASP1 in acute myeloid leukemia

Liu, J. L., Zhao, M., Feng, X., Zeng, Y., & Lin, D. (2021) · Aging · doi:10.18632/aging.203028 · Cited by 14

Regulation of neural stem cell proliferation and survival by protein arginine methyltransferase 1

Hashimoto, M., Takeichi, K., Murata, K., Kozakai, A., Yagi, A., Ishikawa, K., Suzuki-Nakagawa, C., Kasuya, Y., Fukamizu, A., & Nakagawa, T. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.948517 · Cited by 13

Simultaneous aberrations of single CDKN2A network components and a high Rb phosphorylation status can differentiate subgroups of primary cutaneous B-cell lymphomas

Kaune, K. M., Neumann, C. R., Hallermann, C., Haller, F., Schön, M. P., & Middel, P. (2011) · Experimental Dermatology · doi:10.1111/j.1600-0625.2010.01226.x · Cited by 13

Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence

Bainor, A. J., Deng, F., Wang, Y., Lee, P., Cantor, D. J., Logan, S. K., & David, G. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-3410 · Cited by 13

Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation

Shi, X., Yang, J., Mao, N., Wu, J., Ren, L., Yang, Y., Yin, X.-L., Wei, L., Li, M., & Wang, B. (2014) · Acta Pharmacologica Sinica · doi:10.1038/aps.2014.106 · Cited by 13

Pattern of Expression of p53, Its Family Members, and Regulators during Early Ocular Development and in the Post-Mitotic Retina

Vuong, L., Brobst, D. E., Saadi, A., Ivanovic, I., & Al‐Ubaidi, M. R. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-8681 · Cited by 13

A systematic approach to prioritize drug targets using machine learning, a molecular descriptor-based classification model, and high-throughput screening of plant derived molecules: a case study in oral cancer

Randhawa, V., Singh, A. K., & Acharya, V. (2015) · Molecular BioSystems · doi:10.1039/c5mb00468c · Cited by 13

Characterization of the 5’-flanking region of the humanTP53gene and its response to the natural compound, Resveratrol

Uchiumi, F., Shoji, K., Sasaki, Y., Sasaki, M., Sasaki, Y., Oyama, T., Sugisawa, K., & Tanuma, S.-I. (2015) · The Journal of Biochemistry · doi:10.1093/jb/mvv126 · Cited by 13

Loss of ENT1 increases cell proliferation in the annulus fibrosus of the intervertebral disc

Veras, M. A., Tenn, N. A., Kuljanin, M., Lajoie, G., Hammond, J. R., Dixon, S. J., & Séguin, C. A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28051 · Cited by 13

Rapamycin Attenuates H2O2-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts

Tang, Y., Yang, S., Qiu, Z., Guan, L., Wang, Y., Li, G., Tu, Y., & Guo, L. (2024) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-024-00660-2 · Cited by 12

E2F1 activates p53 transcription through its distal site and participates in apoptosis induction in HPV‐positive cells

Massip, A., Arcondéguy, T., Touriol, C., Basset, C., Prats, H., & Lacazette, É. (2013) · FEBS Letters · doi:10.1016/j.febslet.2013.08.009 · Cited by 12

Identification of a Low-Frequency Missense Variant in E2F Transcription Factor 7 Associated with Colorectal Cancer Risk In A Chinese Population

Guo, A.-Y., Zhai, K., Xu, J., Hu, J. L., & Gao, L. (2017) · Europe PMC (PubMed Central) · doi:10.22034/apjcp.2017.18.1.271 · Cited by 12

E2F1 promotes Warburg effect and cancer progression via upregulating ENO2 expression in Ewing sarcoma

Jiang, X., Chen, Z., Zhu, J., Han, J., You, G., Li, Y., Liu, T., & Ye, H. (2022) · Molecular Medicine Reports · doi:10.3892/mmr.2022.12753 · Cited by 13

Encoding and Decoding of p53 Dynamics in Cellular Response to Stresses

Wang, P., Wang, H., Gao, X., Zhu, H.-X., Zhang, X., Liu, F., & Wang, W. (2023) · Cells · doi:10.3390/cells12030490 · Cited by 13

p53/E2F7 axis promotes temozolomide chemoresistance in glioblastoma multiforme

Jiao, M., Qian, W., Yang, Z., Gong, L., Xu, D., Huang, H., Jiang, X., Pu, Z., Yin, Y., & Zou, J. (2024) · BMC Cancer · doi:10.1186/s12885-024-12017-y · Cited by 14

Next-Generation Sequencing of Colorectal Cancers in Chinese: Identification of a Recurrent Frame-Shift and Gain-of-Function Indel Mutation in the TFDP1 Gene

Chen, C., Liu, J., Zhou, F., Sun, J., Li, L., Jin, C., Shao, J., Jiang, H., Zhao, N., Zheng, S. S., et al. (2014) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2014.0058 · Cited by 12

E2F1 Expression and Apoptosis Initiation in Crayfish and Rat Peripheral Neurons and Glial Cells after Axonal Injury

Dzreyan, V., Eid, M., Rodkin, S., Pitinova, M., & Demyanenko, S. V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084451 · Cited by 11

Prognostic value and gene regulatory network of CMSS1 in hepatocellular carcinoma

Chen, C., Wang, C., Liu, W., Chen, J., Chen, L., Luo, X., & Wu, J. (2023) · Cancer Biomarkers · doi:10.3233/cbm-230209 · Cited by 11

Different Mechanisms in Doxorubicin-Induced Cardiomyopathy: Impact of BRCA1 and BRCA2 Mutations

Nguyen, H. C., Frisbee, J. C., & Singh, K. K. (2024) · Hearts · doi:10.3390/hearts5010005 · Cited by 11

Astroglial U87 Cells Protect Neuronal SH-SY5Y Cells from Indirect Effect of Radiation by Reducing DNA Damage and Inhibiting Fas Mediated Apoptotic Pathway in Coculture System

Saeed, Y., Rehman, A., Xie, B., Xu, J., Ma, H., Hong, Q., & Deng, Y. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1642-x · Cited by 11

To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage

Kollárovič, G., Studencka‐Turski, M., Ivanova, L., Lauenstein, C., Heinze, K., Lapytsko, A., Talemi, S. R., Figueiredo, A. S., & Schaber, J. (2016) · Aging · doi:10.18632/aging.100883 · Cited by 11

Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer

Munro, S., Oppermann, U. C. T., & Thangue, N. B. L. (2013) · Oncogene · doi:10.1038/onc.2013.316 · Cited by 11

E2F‐1‐ and E2Ftr‐mediated apoptosis: the role of DREAM and HRK

Hao, H., Chen, C., Rao, X., Gómez-Gutiérrez, J. G., Zhou, H. S., & McMasters, K. M. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01338.x · Cited by 13

Requirement for phosphorylation of P53 at Ser312 in suppression of chemical carcinogenesis

Slee, E. A., & Lü, X. (2013) · Scientific Reports · doi:10.1038/srep03105 · Cited by 10

Opportunities and Challenges for Nutritional Proteomics in Cancer Prevention,

Romagnolo, D. F., & Milner, J. A. (2012) · Journal of Nutrition · doi:10.3945/jn.111.151803 · Cited by 10

Validation of a Multiplexed Gene Signature Assay for Diagnosis of Canine Cancers from Formalin-Fixed Paraffin-Embedded Tissues

Davis, B. J., Schwartz, M., Duchemin, D., Barrett, J. C., & Post, G. S. (2017) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.14686 · Cited by 10

Cell cycle regulatory molecular profiles of pediatric T-cell lymphoblastic leukemia and lymphoma

Bonn, B. R., Krieger, D., & Burkhardt, B. (2011) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2011.616614 · Cited by 10

Deciphering TGF-β1's role in drug resistance and leveraging plant bioactives for cancer therapy

Deb, V. K., Chauhan, N., & Jain, U. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.177218 · Cited by 10

E2F1‐dependent pathways are involved in amonafide analogue 7‐d‐induced DNA damage, G2/M arrest, and apoptosis in p53‐deficient K562 cells

Li, Y., Shao, J., Shen, K., Xu, Y. F., Liu, J., & Qian, X. H. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24194 · Cited by 9

A subset of microRNAs potentially acts as a convergent hub for upstream transcription factors in cancer cells

Yoshida (2010) · Oncology Reports · doi:10.3892/or_00000995 · Cited by 9

DGKζ ablation engenders upregulation of p53 level in the spleen upon whole-body ionizing radiation

Tanaka, T., Iseki, K., Tanaka, K., Nakano, T., Iino, M., & Goto, K. (2017) · Advances in Biological Regulation · doi:10.1016/j.jbior.2017.09.010 · Cited by 10

CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma

Xiong, Y., Lei, J., Wen, M., Ma, Y., Zhao, J., Tian, Y., Wan, Z., Li, X., Zhu, J., Wang, W., et al. (2025) · Oncogenesis · doi:10.1038/s41389-025-00546-5 · Cited by 8

The role of epigenetic modifications, long-range contacts, enhancers and topologically associating domains in the regulation of glioma grade-specific genes

Grabowicz, I. E., Wilczyński, B., Kamińska, B., Roura, A.-J., Wojtaś, B., & Dąbrowski, M. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-95009-3 · Cited by 8

Tumor Microenvironment CD8 T and Treg Cells–related Genes Signature Distinguishes Distinct Prognosis and Targeted Therapies Response in Endometrial Cancer

Liu, X., Dingqing, F., Wang, W., Liang, J., Yu, H., & Ling, B. (2023) · Journal of Immunotherapy · doi:10.1097/cji.0000000000000463 · Cited by 8

To Grow, Stop or Die? – Novel Tumor-Suppressive Mechanism Regulated by the Transcription Factor E2F

Ozono, E., Yamaoka, S., & Ohtani, K. (2013) · InTech eBooks · doi:10.5772/54510 · Cited by 9

An epigenomic role of Fe65 in the cellular response to DNA damage

Ryu, S., Teles, F., Minopoli, G., Russo, T., Rosenfeld, M. G., & Suh, Y. (2015) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2015.01.006 · Cited by 8

E2F1 enhances 8-Chloro-adenosine-induced G2/M arrest and apoptosis in A549 and H1299 lung cancer cells

Duan, H.-Y., Cao, J., Qi, J.-J., Wu, G., Li, S., An, G., Jia, H., Cai, W., & Ni, J. (2012) · Biochemistry (Moscow) · doi:10.1134/s0006297912030042 · Cited by 8

Functional variants at the miRNA binding sites of the E2F1 gene and its mRNA expression

Zhao, Y., Tang, L., Nie, W., Wang, Z., & Guan, X. (2012) · Oncology Letters · doi:10.3892/ol.2012.999 · Cited by 8

Lack of association between p53 SNP and FISS in a cat population from Germany

Mucha, D., Laberke, S., Meyer, S., & Hirschberger, J. (2012) · Veterinary and Comparative Oncology · doi:10.1111/j.1476-5829.2012.00344.x · Cited by 8

Future Aspects of Tumor Suppressor Gene

Cheng, Y. (2013) · InTech eBooks · doi:10.5772/56471 · Cited by 8

Chitosan Treatment Delays the Induction of Senescence in Human Foreskin Fibroblast Strains

Tsai, C.-W., Kao, Y.-T., Chiang, I., Wang, J., & Young, T. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140747 · Cited by 8

Distinct and Coordinated Regulation of Small Non-coding RNAs by E2f1 and p53 During Drosophila Development and in Response to DNA Damage

Li, D., Ge, Y., Zhao, Z., Zhu, R., Wang, X., & Bi, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.695311 · Cited by 8

Cariporide Enhances the DNA Damage and Apoptosis in Acid-tolerable Malignant Mesothelioma H-2452 Cells

Lee, Y., Bae, J.-H., Kim, S., Kim, S., Woo, K.-M., Nam, H.-S., Cho, M. K., & Lee, S.-H. (2017) · Molecules and Cells · doi:10.14348/molcells.2017.0059 · Cited by 8

A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma

Yamaguchi, T., Ikehara, S. K., Nakanishi, H., & Ikehara, Y. (2014) · The Journal of Pathology · doi:10.1002/path.4402 · Cited by 7

Loss of E2F1 Extends Survival and Accelerates Oral Tumor Growth in HPV-Positive Mice

Zhong, R., Bechill, J., & Spiotto, M. T. (2015) · Cancers · doi:10.3390/cancers7040895 · Cited by 7

JAZ mediates G1cell cycle arrest by interacting with and inhibiting E2F1

Yang, M., Wu, S., Jia, J., & May, W. S. (2011) · Cell Cycle · doi:10.4161/cc.10.14.16587 · Cited by 7

Dysregulation of the Cyclin D/E2F activity as a core mechanism driving cancer stem cell plasticity and cell cycle dynamics

Ahmadi, Y., Mohammed, T., Abolhasani, S., Hamad, S. A., & Faiq, T. (2025) · Cell Cycle · doi:10.1080/15384101.2025.2599081 · Cited by 6

MDMX elevation by a novel Mdmx–p53 interaction inhibitor mitigates neuronal damage after ischemic stroke

Yan, H., Sasaki, T., Kanki, H., Hirata, Y., Nishiyama, K., Hisada, S., Matsumura, S., Nagaoka, Y., Sumiyoshi, T., Nagano, S., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-25427-4 · Cited by 6

The E2F family: a ray of dawn in cardiomyopathy

Wei, J., Gao, C., Lu, C., Wang, L., Dong, D., & Sun, M. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05063-4 · Cited by 6

NEK2 inhibition alleviates lipopolysaccharide-induced endothelial injury

Fakir, S., Sarker, M. M. R., Sigdel, M., & Barabutis, N. (2025) · ASPET Discovery · doi:10.1016/j.aspetd.2025.100002 · Cited by 6

Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice

Chinnam, M., Wang, X., Zhang, X., & Goodrich, D. W. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.01003-15 · Cited by 6

Modeling osteosarcoma progression by measuring the connectivity dynamics using an inference of multiple differential modules algorithm

Liu, B., Zhang, Z., Dai, E., Tian, J.-X., Xin, J.-Z., & Xu, L. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.6703 · Cited by 6

A CpG island promoter drives the CXXC5 gene expression

Yaşar, P., Kars, G., Yavuz, K., Ayaz, G., Oğuztüzün, Ç., Bilgen, E., Suvacı, Z., Çetinkol, Ö. P., Can, T., & Muyan, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-95165-6 · Cited by 6

The Role of p53-Dependent Signaling Pathways in Survival and Death of Neurons and Glial Cells after Peripheral Nerve Injury

Rodkin, S., Dzreyan, V., Demyanenko, S. V., & Uzdensky, A. B. (2021) · Biochemistry (Moscow) Supplement Series A Membrane and Cell Biology · doi:10.1134/s199074782106009x · Cited by 6

What makes the engine hum

Enserink, J. M., & Kolodner, R. D. (2012) · Cell Cycle · doi:10.4161/cc.11.2.19023 · Cited by 6

Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression

Assawarachan, S. N., Toussaint, M. J. M., Youssef, S. A., Tooten, P. C. J., & de Bruin, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150064 · Cited by 7

Acute loss of DP1, but not DP2, induces p53 mRNA and augments p21Waf1/Cip1 and senescence

Ohdaira, H., Sekiguchi, M., Miyata, K., Sasaki, T., & Yoshida, K. (2012) · Cell Biochemistry and Function · doi:10.1002/cbf.1818 · Cited by 5

MUC1-C auto-regulatory complex with EBNA1 is responsible for latent Epstein-Barr virus-associated gastric cancer progression

Ozawa, H., Wang, Y., Withers, H. G., Haratake, N., Nakashoji, A., Bhattacharya, A., Fushimi, A., Kikutake, C., Yamanoi, K., White, S., et al. (2025) · Oncogene · doi:10.1038/s41388-025-03519-5 · Cited by 5

A testis-specific lncRNA functions as a post-transcriptional regulator of MDM2 and stimulates apoptosis of testicular germ cell tumor cells

Ito, S., Ueno, A., Ueda, T., Ogura, R., Sako, S., Gabata, Y., Murashita, J., Takahashi, H., & Ukimura, O. (2024) · Cell Death Discovery · doi:10.1038/s41420-024-02119-8 · Cited by 5

Chromodomain Helicase DNA‐Binding Protein 5 Inhibits Renal Cell Carcinoma Tumorigenesis by Activation of the p53 and RB Pathways

Huang, S., Yan, Q., Xiong, S., Peng, Y., Zhao, R., & Liu, C. (2020) · BioMed Research International · doi:10.1155/2020/5425612 · Cited by 5

A novel function of HRP‐3 in regulating cell cycle progression via the HDAC–E2F1–Cyclin E pathway in lung cancer

Yun, H. S., Lee, J. S., Kim, J., Sim, Y., Lee, C., Park, J. K., Kim, J., Ahn, J., Song, J. Y., Baek, J., et al. (2021) · Cancer Science · doi:10.1111/cas.15183 · Cited by 5

Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase‐3β in the striatum of rats treated with 3‐nitropropionic acid

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