The first 30 years of p53: growing ever more complex.

WAF1, a potential mediator of p53 tumor suppression

El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., & Vogelstein, B. (1993) · Cell · doi:10.1016/0092-8674(93)90500-p · Cited by 8,321

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., & Lowe, S. W. (1997) · Cell · doi:10.1016/s0092-8674(00)81902-9 · Cited by 5,218 · cited 1×

p53, guardian of the genome

Lane, D. P. (1992) · Nature · doi:10.1038/358015a0 · Cited by 5,138

The retinoblastoma protein and cell cycle control

Weinberg, R. A. (1995) · Cell · doi:10.1016/0092-8674(95)90385-2 · Cited by 4,862

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., et al. (2004) · Science · doi:10.1126/science.1092472 · Cited by 4,661

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., & Bradley, A. (1992) · Nature · doi:10.1038/356215a0 · Cited by 4,649

Mdm2 promotes the rapid degradation of p53

Haupt, Y., Maya, R., Kazaz, A., & Oren, M. (1997) · Nature · doi:10.1038/387296a0 · Cited by 4,506

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki, M., & Reed, J. C. (1995) · Cell · doi:10.1016/0092-8674(95)90412-3 · Cited by 4,063

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., & Howley, P. M. (1990) · Cell · doi:10.1016/0092-8674(90)90409-8 · Cited by 3,995

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

Malkin, D., Li, F. P., Strong, L. C., Fraumeni, J. F., Nelson, C. E., Kim, D. H., Kassel, J., Gryka, M. A., Bischoff, F. Z., Tainsky, M. A., et al. (1990) · Science · doi:10.1126/science.1978757 · Cited by 3,765

Apoptosis-mediated testicular alteration in Japanese quail (Coturnix coturnix japonica) in response to temporal phase relation of serotonergic and dopaminergic oscillations

Banerjee, S., Tsutsui, K., & Chaturvedi, C. M. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.129155 · Cited by 23

VOLIN and KJON—Two novel hyperdiploid myeloma cell lines

Våtsveen, T. K., Børset, M., Dikic, A., Tian, E., Micci, F., Lid, A. H. B., Meza‐Zepeda, L. A., Coward, E., Waage, A., Sundan, A., et al. (2016) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22388 · Cited by 23

Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancer

Hashemi, M. M., Amininia, S., Ebrahimi, M., Simforoosh, N., Basiri, A., Ziaee, S. A. M., Narouie, B., Sotoudeh, M., Mollakouchekian, M. J., Maleki, E. R., et al. (2017) · Oncology Letters · doi:10.3892/ol.2017.5739 · Cited by 23

An integrated method for the identification of novel genes related to oral cancer

Chen, L., Yang, J., Xing, Z., Yuan, F., Shu, Y., Zhang, Y., Kong, X., Huang, T., Li, H., & Cai, Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175185 · Cited by 23

Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence

Sabatino, M. E., Castellaro, A., Racca, A. C., Carbajosa González, S., Pansa, M. F., Soria, G., & Bocco, J. L. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00297 · Cited by 23

Review of Disease-Specific microRNAs by Strategically Bridging Genetics and Epigenetics in Oral Squamous Cell Carcinoma

Gintoni, I., Vassiliou, S., Chrousos, G. P., & Yapijakis, C. (2023) · Genes · doi:10.3390/genes14081578 · Cited by 23

Structural basis of how stress-induced MDMX phosphorylation activates p53

Chen, X., Gohain, N., Zhan, C., Lu, W.-Y., Pazgier, M., & Lu, W. (2015) · Oncogene · doi:10.1038/onc.2015.255 · Cited by 22

Lymphocytes of Patients with Alzheimer’s Disease Display Different DNA Damage Repair Kinetics and Expression Profiles of DNA Repair and Stress Response Genes

Leandro, G. D. S., Lôbo, R. R., Oliveira, D. V. N. P., Moriguti, J. C., & Sakamoto‐Hojo, E. T. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140612380 · Cited by 23

Cell Context Dependent p53 Genome-Wide Binding Patterns and Enrichment at Repeats

Botcheva, K., & McCorkle, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113492 · Cited by 23

Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

Yang, M., Yuan, F., Li, P., Chen, Z., Chen, A., Li, S., & Hu, C. (2012) · Molecular Cancer · doi:10.1186/1476-4598-11-54 · Cited by 23

The mutational status of p53 can influence its recognition by human T-cells

Shamalov, K., Levy, S. N., Horovitz‐Fried, M., & Cohen, C. J. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1285990 · Cited by 23

Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells

Srdić‐Rajić, T., Santibanez, J. F., Kanjer, K., Miletić, N. T., Cavic, M. R., Galun, D., Jevric, M., Kardum, N., Konić‐Ristić, A., & Zoranovic, T. (2017) · Scientific Reports · doi:10.1038/s41598-017-03898-0 · Cited by 23

Long noncoding RNA s: A new player in the prevention and treatment of diabetic cardiomyopathy?

Ma, C., Luo, H., Liu, B., Li, F., Tschöpe, C., & Fa, X. (2018) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3056 · Cited by 22

Characterizing Cancer Drug Response and Biological Correlates: A Geometric Network Approach

Pouryahya, M., Oh, J. H., Mathews, J. C., Deasy, J. O., & Tannenbaum, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-24679-3 · Cited by 23

p53: An Attractive Therapeutic Target for Cancer

Patel, K. R., & Patel, H. D. (2019) · Current Medicinal Chemistry · doi:10.2174/1573406415666190621094704 · Cited by 24

Toxic effects of 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal on the maturation and subsequent development of murine oocyte

Liu, H., Liu, Z., Lu, T., Zhang, L., Cheng, J., Fu, X., & Hou, Y. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.06.006 · Cited by 23

Theaflavin Induces Apoptosis of A375 Human Melanoma Cells and Inhibits Tumor Growth in Xenograft Zebrafishes Through P53- and JNK-Related Mechanism

Zhang, L., Yan, B., Meng, S., Zhou, L., Xu, Y., Du, W., & Shan, L. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01317 · Cited by 23

Crosstalk Between Vitamin D and p53 Signaling in Cancer: An Update

Reichrath, J., Reichrath, S., VOGT, T. M., & Römer, K. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-46227-7_15 · Cited by 23

Viral Infections: Negative Regulators of Apoptosis and Oncogenic Factors

Zamaraev, A. V., Zhivotovsky, B., & Kopeina, G. S. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920100077 · Cited by 22

The can and can’t dos of p53 RNA

Candeias, M. M. (2011) · Biochimie · doi:10.1016/j.biochi.2011.06.010 · Cited by 23

Transcription factor-pathway coexpression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma

Wang, X., Yan, Z., Fulciniti, M., Li, Y., Gkotzamanidou, M. A., Amin, S. B., Shah, P. K., Zhang, Y., Munshi, N. C., & Li, C. (2013) · Leukemia · doi:10.1038/leu.2013.233 · Cited by 24

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage

Velalopoulou, A., Chatterjee, S., Pietrofesa, R., Koziol-White, C., Panettieri, R., Lin, L., Tuttle, S., Berman, A., Koumenis, C., & Christofidou-Solomidou, M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18122525 · Cited by 22

APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based radiotherapy

Michaeli, O., Luz, I., Vatarescu, M., Manko, T., Weizman, N., Korotinsky, Y., Tsitrina, A. A., Braiman, A., Arazi, L., & Cooks, T. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06830-3 · Cited by 23

Flavonoids and Tannins from Smilax china L. Rhizome Induce Apoptosis Via Mitochondrial Pathway and MDM2-p53 Signaling in Human Lung Adenocarcinoma Cells

Fu, S., Yang, Y., Liu, D., Luo, Y., Ye, X., Liu, Y., Chen, X., Wang, S., Wu, H., Wang, Y., et al. (2017) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x17500239 · Cited by 22

Urokinase plasminogen activator protects cardiac myocytes from oxidative damage and apoptosis via hOGG1 induction

Hohensinner, P. J., Takács, N. M., Kaun, C., Thaler, B., Krychtiuk, K. A., Pfaffenberger, S., Aliabadi, A. Z., Zuckermann, A. O., Huber, K., & Wojta, J. (2017) · APOPTOSIS · doi:10.1007/s10495-017-1388-9 · Cited by 22

Viral Carcinogenesis

Smith, A. J., & Smith, L. A. (2016) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2016.09.007 · Cited by 23

PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer

Li, Q., Hao, Q., Cao, W., Li, J., Wu, K., Elshimali, Y., Zhu, D., Chen, Q., Chen, G., Pollack, J. R., et al. (2019) · Science Advances · doi:10.1126/sciadv.aaw8417 · Cited by 23

Exposure to Dimethyl Selenide (DMSe)-Derived Secondary Organic Aerosol Alters Transcriptomic Profiles in Human Airway Epithelial Cells

Ahmed, C. M. S., Cui, Y., Frie, A. L., Burr, A. C., Kamath, R., Chen, J. Y., Rahman, A., Nordgren, T. M., Lin, Y., & Bahreini, R. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b04376 · Cited by 22

Coding and noncoding somatic mutations in candidate genes in basal cell carcinoma

Maturo, M. G., Rachakonda, P. S., Heidenreich, B., Pellegrini, C., Srinivas, N., Requena, C., Serra-Guillén, C., Llombart, B., Sanmartín, O., Guillén, C., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-65057-2 · Cited by 22

Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association

Santos, J., Pallarès, I., Iglesias, V., & Ventura, S. (2021) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2021.07.019 · Cited by 22

Developmental Acquisition of p53 Functions

Jaiswal, S. K., Raj, S., & Depamphilis, M. (2021) · Genes · doi:10.3390/genes12111675 · Cited by 23

Disruption of the mevalonate pathway induces dNTP depletion and DNA damage

Martín-Sánchez, C., Martín, J. M. P., Jin, J., Dávalos, A., Zhang, W., de la Peña, G., Martı́nez-Botas, J., Rodríguez‐Acebes, S., Suárez, Y., Hazen, M. J., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2015.06.001 · Cited by 22

PDCD5 functions as a regulator of p53 dynamics in the DNA damage response

Zhuge, C., Sun, X., Chen, Y., & Lei, J. (2015) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2015.09.025 · Cited by 23

The emerging role of Mule and ARF in the regulation of base excision repair

Khoronenkova, S. V., & Dianov, G. L. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.06.015 · Cited by 23

p53 restoration kills primitive leukemia cells in vivo and increases survival of leukemic mice

Velasco-Hernández, T., Vicente‐Dueñas, C., Sánchez-Garcı́a, I., & Martı́n-Zanca, D. (2012) · Cell Cycle · doi:10.4161/cc.23031 · Cited by 23

p53 immunohistochemical expression and patient prognosis in esophageal squamous cell carcinoma

Murata, A., Baba, Y., Watanabe, M., Shigaki, H., Miyake, K., Karashima, R., Imamura, Y., Ida, S., Ishimoto, T., Iwagami, S., et al. (2013) · Medical Oncology · doi:10.1007/s12032-013-0728-z · Cited by 22

Oleiferasaponin C 6 from the seeds of Camellia oleifera Abel.: a novel compound inhibits proliferation through inducing cell-cycle arrest and apoptosis on human cancer cell lines in vitro

Zong, J.-F., Wang, D., Jiao, W., Zhang, L., Bao, G., Ho, C., Hou, R., & Wan, X. (2016) · RSC Advances · doi:10.1039/c6ra14467e · Cited by 22

Proteasome inhibitor MG132 induces thyroid cancer cell apoptosis by modulating the activity of transcription factor FOXO3a

Qiang, W., Sui, F., Ma, J., Li, X., Ren, X., Shao, Y., Liu, J., Guan, H., Shi, B., & Hou, P. (2017) · Endocrine · doi:10.1007/s12020-017-1256-y · Cited by 23

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization

Cubillos‐Rojas, M., Schneider, T., Bartrons, R., Ventura, F., & Rosa, J. L. (2017) · Oncotarget · doi:10.18632/oncotarget.18699 · Cited by 22

A role for caspase‐2 in sphingosine kinase 1 proteolysis in response to doxorubicin in breast cancer cells – implications for the CHK 1‐suppressed pathway

Carroll, B. L., Bonica, J., Shamseddine, A. A., Hannun, Y. A., & Obeid, L. M. (2017) · FEBS Open Bio · doi:10.1002/2211-5463.12344 · Cited by 22

TP53 alterations and colorectal cancer predisposition in south Indian population: A case-control study

Singamsetty, G. K., Malempati, S., Bhogadhi, S., Kondreddy, R., Govatati, S., Tangudu, N. K., Govatati, S., kuraganti, A. K., Bhanoori, M., & Kassetty, K. (2013) · Tumor Biology · doi:10.1007/s13277-013-1305-y · Cited by 22

Human pancreatic cancer progression: an anarchy among CCN-siblings

Banerjee, S. K., Maity, G., Haque, I., Ghosh, A., Sarkar, S., Gupta, V. G., Campbell, D. R., Hoff, D. D. V., & Banerjee, S. (2016) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-016-0343-9 · Cited by 21

Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3

Yang, P., Chen, W., Li, X., Eilers, G., He, Q., Liu, L., Wu, Y., Wu, Y., Yu, W., Fletcher, J. A., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.8999 · Cited by 21

Strategies for p53 Activation and Targeted Inhibitors of the p53-Mdm2/MdmX Interaction

Huang, Y., Wang, L., Zhou, Y., Bai, J., Li, N., Su, Z., & Cheng, X. (2025) · Cells · doi:10.3390/cells14080583 · Cited by 25

Neurodegeneration rewires the tumor microenvironment via the neuro–immune–cancer axis

Bautista, J., Coral-Riofrio, E. C., Urresta, S. S., Palacios-Zavala, D., Echeverría, C. E., Araujo‐Abad, S., & López‐Cortés, A. (2025) · iScience · doi:10.1016/j.isci.2025.113550 · Cited by 22

Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation

Charni, M., Molchadsky, A., Goldstein, I., Solomon, H., Tal, P., Goldfinger, N., Yang, P., Porat, Z., Lozano, G., & Rotter, V. (2015) · Cell Death and Differentiation · doi:10.1038/cdd.2015.119 · Cited by 21

Molecular Pathogenesis and Current Therapy in Intrahepatic Cholangiocarcinoma

Høgdall, D., O’Rourke, C. J., Taranta, A., Oliveira, D. V. N. P., & Andersen, J. B. (2016) · Digestive Diseases · doi:10.1159/000444562 · Cited by 21

Y-box Binding Protein 1: Looking Back to the Future

Evdokimova, V. E. (2022) · Biochemistry (Moscow) · doi:10.1134/s0006297922140024 · Cited by 22

Analyzing aberrant DNA methylation in colorectal cancer uncovered intangible heterogeneity of gene effects in the survival time of patients

Khaniki, S. H., Shokoohi, F., Esmaily, H., & Kerachian, M. A. (2023) · Scientific Reports · doi:10.1038/s41598-023-47377-1 · Cited by 23

The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress

Jansen, J., Bohnsack, K. E., Böhlken-Fascher, S., Bohnsack, M. T., & Dobbelstein, M. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114610 · Cited by 21

RNF125 is a Ubiquitin-Protein Ligase that Promotes p53 Degradation

Yang, L., Zhou, B., Li, X., Lu, Z., Li, W., Huo, X., & Miao, Z. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000369691 · Cited by 21

ETME, a novel β-elemene derivative, synergizes with arsenic trioxide in inducing apoptosis and cell cycle arrest in hepatocarcinoma cells via a p53-dependent pathway

Yu, Z., Wu, F., Chen, L., Li, Q., Wang, C., Dong, J., & Xie, S. (2014) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2014.10.001 · Cited by 21

Cell fate conversion: Direct induction of hepatocyte‐like cells from fibroblasts

Ji, S., Zhang, L., & Hui, L. (2012) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24380 · Cited by 21

Magnetic Fe3O4 nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells

Chen, B., Wang, J., & Xia, G. (2010) · International Journal of Nanomedicine · doi:10.2147/ijn.s14957 · Cited by 21

Synergistic Interaction of Rnf8 and p53 in the Protection against Genomic Instability and Tumorigenesis

Halaby, M., Hakem, A., Li, L., Ghamrasni, S. E., Venkatesan, S., Hande, M. P., Sanchez, O. H., & Hakem, R. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003259 · Cited by 21

The tumor suppressor p53 induces expression of the pregnancy-supporting human chorionic gonadotropin (hCG) CGB7 gene

Sohr, S., & Engeland, K. (2011) · Cell Cycle · doi:10.4161/cc.10.21.17946 · Cited by 22

Impact of Cellular Senescence in Aging and Cancer

Provinciali, M., Cardelli, M., Marchegiani, F., & Pierpaoli, E. (2013) · Current Pharmaceutical Design · doi:10.2174/138161213805219739 · Cited by 21

Lessons from interconnected ubiquitylation and acetylation of p53: think metastable networks

Benkirane, M., Sardet, C., & Coux, O. (2010) · Biochemical Society Transactions · doi:10.1042/bst0380098 · Cited by 24

Solution structure and binding specificity of the p63 DNA binding domain

Enthart, A., Klein, C., Dehner, A., Coles, M. P., Gemmecker, G., Kessler, H., & Hagn, F. (2016) · Scientific Reports · doi:10.1038/srep26707 · Cited by 21

Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells

Xu, W., Wang, B., Yang, M., Zhang, Y., Xu, Z., Yang, Y., Cao, H., & Tao, L. (2016) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2016.12.002 · Cited by 21

Correlation between epidermal growth factor receptor mutations and the expression of estrogen receptor-β in advanced non-small cell lung cancer

Deng, F., Li, M., Shan, W., Qian, L.-T., Meng, S.-P., Zhang, X., & Wang, B. (2017) · Oncology Letters · doi:10.3892/ol.2017.5711 · Cited by 21

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high‐throughput screening approach to measure p53 activation

Witt, K. L., Hsieh, J., Smith‐Roe, S. L., Xia, M., Huang, R., Zhao, J., Auerbach, S. S., Hur, J., & Tice, R. R. (2017) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22112 · Cited by 21

NFAT5 is Regulated by p53/miR-27a Signal Axis and Promotes Mouse Ovarian Granulosa Cells Proliferation

Tao, H., Xiong, Q., Ji, Z., Zhang, F., Liu, Y., & Chen, M. (2019) · International Journal of Biological Sciences · doi:10.7150/ijbs.29273 · Cited by 21

P53 and Apoptosis in the Drosophila Model

Zhou, L. J. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-23629-8_6 · Cited by 20

Crataegus Extract WS®1442 Stimulates Cardiomyogenesis and Angiogenesis From Stem Cells: A Possible New Pharmacology for Hawthorn?

Halver, J., Wenzel, K., Sendker, J., García, C. C., Erdelmeier, C. A. J., Willems, E., Mercola, M. A., Symma, N., Könemann, S., Koch, E., et al. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01357 · Cited by 21

The foundational framework of tumors: Gametogenesis, p53, and cancer

Liu, C., Moten, A., Ma, Z., & Lin, H. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.04.018 · Cited by 21

The p53 transcriptional response across tumor types reveals core and senescence-specific signatures modulated by long noncoding RNAs

Tesfaye, E., Martínez‐Terroba, E., Bendor, J., Winkler, L., Olivero, C. E., Chen, K., Feldser, D. M., Zamudio, J. R., & Dimitrova, N. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2025539118 · Cited by 21

The tissue dependent interactions between p53 and Bcl-2 in vivo

Li, X., Miao, X., Wang, H., Xu, Z., & Ли, Б. (2015) · Oncotarget · doi:10.18632/oncotarget.5372 · Cited by 20

Connections between 3′ end processing and DNA damage response: Ten years later

Murphy, M. R., & Kleiman, F. E. (2019) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1571 · Cited by 21

Protecting the genome from mdm2 and mdmx

Melo, A. N., & Eischen, C. M. (2012) · Genes & Cancer · doi:10.1177/1947601912454139 · Cited by 20

Characterization and Clinical Implications of p53 Dysfunction in Patients With Myelodysplastic Syndromes

Zampini, M., Riva, E., Lanino, L., Sauta, E., Reis, R. A. D., Ejarque, R. A., Maggioni, G., Termanini, A., Merlotti, A., Campagna, A., et al. (2025) · Journal of Clinical Oncology · doi:10.1200/jco-24-02394 · Cited by 21

The structure formed by inverted repeats in p53 response elements determines the transactivation activity of p53 protein

Brázda, V., Čechová, J., Battistin, M., Coufal, J., Jagelská, E. B., Raimondi, I., & Inga, A. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.12.113 · Cited by 20

Light‐emitting diode irradiation induces AKT/mTOR‐mediated apoptosis in human pancreatic cancer cells and xenograft mouse model

Kim, Y. M., Ko, S., Shin, Y., Kim, Y., Kim, T. P., Jung, J., Lee, S., Kim, N. G., Park, K., & Ryu, J. H. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29943 · Cited by 20

Centromere protein N may be a novel malignant prognostic biomarker for hepatocellular carcinoma

Wang, Q., Yu, X., Zheng, Z., Chen, F., Yang, N., & Zhou, Y. (2021) · PeerJ · doi:10.7717/peerj.11342 · Cited by 20

GET4 is a novel driver gene in colorectal cancer that regulates the localization of BAG6, a nucleocytoplasmic shuttling protein

Koike, K., Masuda, T., Sato, K., Fujii, A., Wakiyama, H., Tobo, T., Takahashi, J., Motomura, Y., Nakano, T., Saito, H., et al. (2021) · Cancer Science · doi:10.1111/cas.15174 · Cited by 18

Biomarkers in the Occurrence and Development of Pterygium

He, S., & Wu, Z. (2022) · Ophthalmic Research · doi:10.1159/000523878 · Cited by 23

Safety and Efficacy of Humanized Versus Murinized CD19 and CD22 CAR T-Cell Cocktail Therapy for Refractory/Relapsed B-Cell Lymphoma

Huang, L., Li, J., Yang, J., Zhang, X., Zhang, X., He, J., Zhang, G., Li, W., Wang, H., Li, J., et al. (2022) · Cells · doi:10.3390/cells11244085 · Cited by 20

NAD+ Metabolism in Age-Related Hearing Loss

Kim, H. (2014) · Aging and Disease · doi:10.14336/ad.2014.0500150 · Cited by 20

ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair

Polonio-Vallon, T., Krüger, D., & Hofmann, T. G. (2014) · Frontiers in Oncology · doi:10.3389/fonc.2014.00148 · Cited by 23

Association of p53 Arg72Pro Polymorphism with Esophageal Cancer: A Meta-Analysis Based on 14 Case-Control Studies

Zhao, L., Zhao, X., Wu, X., & Tang, W. (2013) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2013.0103 · Cited by 20

Interplay between Parkin and p53 Governs a Physiological Homeostasis That Is Disrupted in Parkinson's Disease and Cerebral Cancer

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LincRNAs and base modifications of p53 induced by arsenic methylation in workers

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Improvement of gemcitabine sensitivity of p53-mutated pancreatic cancer MiaPaCa-2 cells by RUNX2 depletion-mediated augmentation of TAp73-dependent cell death

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Identification and characterization of a metastatic suppressor BRMS 1L as a target gene of p53

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Genome‐scale analysis to identify prognostic markers and predict the survival of lung adenocarcinoma

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p53-TP53-Induced Glycolysis Regulator Mediated Glycolytic Suppression Attenuates DNA Damage and Genomic Instability in Fanconi Anemia Hematopoietic Stem Cells

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Identification and validation of microRNAs that synergize with miR-34a – a basis for combinatorial microRNA therapeutics

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p53 dynamics in single cells are temperature-sensitive

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Network hub-node prioritization of gene regulation with intra-network association

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p53 Activation in Genetic Disorders: Different Routes to the Same Destination

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Testosterone modulates FoxO3a and p53-related genes to protect C2C12 skeletal muscle cells against apoptosis

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Genomics of aggressive B-cell lymphoma

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Notch and the p53 Clan of Transcription Factors

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Myelodysplasia Syndrome, Clonal Hematopoiesis and Cardiovascular Disease

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Differences in the Relative Abundance of ProBDNF and Mature BDNF in A549 and H1299 Human Lung Cancer Cell Media

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Circular RNA circNIPBL promotes NNK-induced DNA damage in bronchial epithelial cells via the base excision repair pathway

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Circular RNAs play roles in regulatory networks of cell signaling pathways in human cancers

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Phosphorylation of IGFBP-3 by Casein Kinase 2 Blocks Its Interaction with Hyaluronan, Enabling HA-CD44 Signaling Leading to Increased NSCLC Cell Survival and Cisplatin Resistance

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Gain-of-function mutant p53: history and speculation

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A comprehensive study of p53 protein

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p53 Tumor Suppressor Protein

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Introduction: p53 – the first twenty years

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A History of Cancer Research: The P53 Pathway.Preprint

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